Publications
Below you can find a list of our published research.
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Below you can find a list of our published research.
7144 results
Cited 3 times since 2023 (1.3 per year) source: EuropePMC
Prenatal diagnosis, Volume 43, Issue 5, 17 3 2023, Pages 629-638 Short-term outcome after the prenatal diagnosis of right aortic arch. Bet BB, Snoep MC, van Leeuwen E, Linskens IH, Haak MC, Rozendaal L, Knobbe I, van Schuppen J, Hoekstra CEL, Koolbergen DR, Clur SA, Pajkrt E
Objectives: To determine the proportion of children that require surgery in the first year of life and thereafter in order to improve the counseling of parents with a fetus with a right aortic arch (RAA). Methods: Fetuses diagnosed with isolated RAA, defined as the absence of intra- or extracardiac anomalies, between 2007 and 2021 were extracted from the prospective registry PRECOR. Results: In total, 110 fetuses were included, 92 with a prenatal diagnosis of RAA and 18 with double aortic arch (... Abstract
The Behavioral and brain sciences, Volume 46, 17 3 2023, Pages e5 Putting the cart before the horse? The origin of information donation. Burkart JM, Sehner S, Brügger RK, Adriaense JEC, van Schaik CP
Heintz & Scott-Phillips propose that the partner choice ecology of our ancestors required Gricean cognitive pragmatics for reputation management, which caused a tendency toward showing and expecting prosociality that subsequently scaffolded language evolution. Here, we suggest a cognitively leaner explanation that is more consistent with comparative data and posits that prosociality and eventually language evolved along with cooperative breeding. Abstract
Cited 5 times since 2023 (2.1 per year) source: EuropePMC
Clinical cardiology, Volume 46, Issue 4, 17 3 2023, Pages 407-415 Addressing current challenges in optimization of lipid management following an ACS event: Outcomes of the ACS EuroPath III initiative. Catapano AL, De Caterina R, Jukema JW, Klempfner R, Landmesser U, Schiele F, Sionis A
Background: Low-density lipoprotein cholesterol (LDL-C) lowering is key to reduce atherosclerotic disease progression and recurrent events for patients after acute coronary syndrome (ACS). However, LDL-C management for post-ACS patients remains challenging in clinical practice. Hypothesis: The ACS EuroPath III project was designed to optimize LDL-C management in post-ACS patients by promoting guideline implementation and translating existing evidence into effective actions. Methods: Three survey... Abstract
Annals of medicine and surgery (2012), Volume 85, Issue 2, 17 3 2023, Pages 130-135 Evaluation of the coexistence of pilonidal sinus disease and hirsutism in female patients: a retrospective cross-sectional study. Akbulut S, Caliskan A, Yilmaz D, Atay A, Garzali IU, Yagmur Y
This study aimed to investigate the coexistence of pilonidal sinus disease (PSD) and hirsutism in female patients. Materials and methods: The demographic and clinical data of 164 female patients who underwent surgery for PSD between January 2007 and May 2014 were evaluated for this retrospective cross-sectional study. Data collected for this study were age, BMI, the modified Ferriman and Gallwey scale (mFGS) for hirsutism, main symptoms, type of surgery, early postoperative complications (wound... Abstract
Cited 10 times since 2023 (4.3 per year) source: EuropePMC
Acta dermato-venereologica, Volume 103, 16 3 2023, Pages adv00872 Effectiveness of Upadacitinib in Patients with Atopic Dermatitis including those with Inadequate Response to Dupilumab and/or Baricitinib: Results from the BioDay Registry. Boesjes CM, Van der Gang LF, Zuithoff NPA, Bakker DS, Spekhorst LS, Haeck I, Kamsteeg M, De Graaf M, De Bruin-Weller MS
Clinical trials showed that upadacitinib, a selective Janus kinase-1 inhibitor, is effective for treatment of moderate-to-severe atopic dermatitis. However, daily practice studies are limited. This multicentre prospective study evaluated the effectiveness of 16 weeks of upadacitinib treatment for moderate-to-severe atopic dermatitis in adult patients, including those with previous inadequate response to dupilumab and/or baricitinib, in daily practice. A total of 47 patients from the Dutch BioDay... Abstract
Cited 3 times since 2023 (1.3 per year) source: EuropePMC
Journal of clinical research in pediatric endocrinology, Volume 15, Issue 2, 16 3 2023, Pages 190-198 Can Serum 25-Hydroxy Vitamin D Levels Predict the Severity of Multisystem Inflammatory Syndrome in Children and COVID-19? Ekemen Keleş Y, Yılmaz D, Taşar S, Üstündağ G, Şahin A, Tuz AE, Arslan Maden A, Kara Aksay A, Çolak A, Karadağ Öncel E
Objective: To determine the clinical significance of serum 25-hydroxy (OH) vitamin D levels in pediatric patients with multisystem inflammatory syndrome in children (MIS-C) and compare the vitamin D levels of these patients with those patients with Coronavirus disease-2019 (COVID-19) and healthy controls. Methods: This study was designed for pediatric patients aged 1 month to 18 years and conducted between July 14 and December 25, 2021. Fifty-one patients with MIS-C, 57 who were hospitalized wit... Abstract
Cited 7 times since 2023 (3 per year) source: EuropePMC
BMJ medicine, Volume 2, Issue 1, 14 2 2023, Pages e000245 Sex differences in cardiovascular complications and mortality in hospital patients with covid-19: registry based observational study. Hockham C, Linschoten M, Asselbergs FW, Ghossein C, Woodward M, Peters SAE, CAPACITY-COVID Collaborative Consortium
Objective: To assess whether the risk of cardiovascular complications of covid-19 differ between the sexes and to determine whether any sex differences in risk are reduced in individuals with pre-existing cardiovascular disease. Design: Registry based observational study. Setting: 74 hospitals across 13 countries (eight European) participating in CAPACITY-COVID (Cardiac complicAtions in Patients With SARS Corona vIrus 2 regisTrY), from March 2020 to May 2021. Participants: All adults (aged ≥18 y... Abstract
Cited 2 times since 2023 (0.9 per year) source: EuropePMC
Journal of the peripheral nervous system : JPNS, Volume 28, Issue 1, 14 2 2023, Pages 69-78 B-cell and T-cell receptor repertoire in chronic inflammatory demyelinating polyneuropathy, a prospective cohort study. van Lieverloo GGA, Al-Soudi A, Wieske L, Klarenbeek PL, Anang DC, Adrichem ME, Niewold I, van Schaik BDC, van Kampen AHC, van Schaik IN, de Vries N, Eftimov F
The immunopathophysiological mechanisms underlying chronic inflammatory demyelinating polyneuropathy (CIDP) in an individual patient are largely unknown. Better understanding of these mechanisms may aid development of biomarkers and targeted therapies. Both B- and T-cell dominant mechanisms have been implicated. We therefore investigated whether B-cell and T-cell receptor (BCR/TCR) repertoires might function as immunological biomarkers in CIDP. In this prospective cohort study, we longitudinally... Abstract
Cited 9 times since 2023 (3.8 per year) source: EuropePMC
The Science of the total environment, Volume 873, 14 2 2023, Pages 162209 Rise and fall of SARS-CoV-2 variants in Rotterdam: Comparison of wastewater and clinical surveillance. Izquierdo-Lara RW, Heijnen L, Oude Munnink BB, Schapendonk CME, Elsinga G, Langeveld J, Post J, Prasad DK, Carrizosa C, Been F, van Beek J, Schilperoort R, Vriend R, Fanoy E, de Schepper EIT, Sikkema RS, Molenkamp R, Aarestrup FM, Medema G, Koopmans MPG, de Graaf M
Monitoring of SARS-CoV-2 in wastewater (WW) is a promising tool for epidemiological surveillance, correlating not only viral RNA levels with the infection dynamics within the population, but also to viral diversity. However, the complex mixture of viral lineages in WW samples makes tracking of specific variants or lineages circulating in the population a challenging task. We sequenced sewage samples of 9 WW-catchment areas within the city of Rotterdam, used specific signature mutations from indi... Abstract
Cited 1 times since 2023 (0.4 per year) source: EuropePMC
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Volume 53, Issue 5, 13 2 2023, Pages 582-585 Muscle and joint pain during dupilumab treatment for atopic dermatitis: Lack of association with antinuclear antibodies. Boesjes CM, van Emst M, Bakker DS, Spekhorst LS, van Wijk F, de Graaf M, de Bruin-Weller MS
Cited 2 times since 2023 (0.9 per year) source: EuropePMC
Annals of vascular surgery, Volume 93, 10 2 2023, Pages 308-318 Learning Curve Analysis of Complex Endovascular Aortic Repair. Warmerdam BWCM, Stevens M, van Rijswijk CSP, Eefting D, van der Meer RW, Putter H, Hamming JF, van der Vorst JR, van Schaik J
Background: When introducing new techniques, attention must be paid to learning curve. Besides quantitative outcomes, qualitative factors of influence should be taken into consideration. This retrospective cohort study describes the quantitative learning curve of complex endovascular aortic repair (EVAR) in a nonhigh-volume academic center and provides qualitative factors that were perceived as contributors to this learning curve. With these factors, we aim to aid in future implementation of new... Abstract
Cited 4 times since 2023 (1.7 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 10, 9 2 2023, Pages 1018167 Thoracic aortopathy in Marfan syndrome overlaps with mechanisms seen in bicuspid aortic valve disease. Grewal N, Dolmaci O, Jansen E, Klautz R, Driessen A, Poelmann RE
Background: Thoracic aortopathy is a serious complication which is more often seen in patients with Marfan syndrome (MFS) and patients with a bicuspid aortic valve (BAV) than in individuals with a tricuspid aortic valve (TAV). The identification of common pathological mechanisms leading to aortic complications in non-syndromic and syndromic diseases would significantly improve the field of personalized medicine. Objective: This study sought to compare thoracic aortopathy between MFS, BAV, and TA... Abstract
Cited 17 times since 2023 (7.2 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 16, Issue 6, 8 2 2023, Pages 837-855 Managing Patients With Moderate Aortic Stenosis. Stassen J, Ewe SH, Pio SM, Pibarot P, Redfors B, Leipsic J, Genereux P, Van Mieghem NM, Kuneman JH, Makkar R, Hahn RT, Playford D, Marsan NA, Delgado V, Ben-Yehuda O, Leon MB, Bax JJ
Current guidelines recommend that clinical surveillance for patients with moderate aortic stenosis (AS) and aortic valve replacement (AVR) may be considered if there is an indication for coronary revascularization. Recent observational studies, however, have shown that moderate AS is associated with an increased risk of cardiovascular events and mortality. Whether the increased risk of adverse events is caused by associated comorbidities, or to the underlying moderate AS itself, is incompletely... Abstract
Cited 5 times since 2023 (2.1 per year) source: EuropePMC
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, Volume 160, 6 1 2023, Pages 114369 Toward model-informed precision dosing for tamoxifen: A population-pharmacokinetic model with a continuous CYP2D6 activity scale. Agema BC, Buijs SM, Sassen SDT, Mürdter TE, Schwab M, Koch BCP, Jager A, van Schaik RHN, Mathijssen RHJ, Koolen SLW
Background: Tamoxifen is important in the adjuvant treatment of breast cancer. A plasma concentration of the active metabolite endoxifen of > 16 nM is associated with a lower risk of breast cancer-recurrence. Since inter-individual variability is high and > 20 % of patients do not reach endoxifen levels > 16 nM with the standard dose tamoxifen, therapeutic drug monitoring is advised. However, ideally, the correct tamoxifen dose should be known prior to start of therapy. Our aim is to de... Abstract
Cited 32 times since 2023 (13.5 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 16, Issue 2, 3 1 2023, Pages e014672 Pericoronary Adipose Tissue Attenuation in Patients With Acute Coronary Syndrome Versus Stable Coronary Artery Disease. Kuneman JH, van Rosendael SE, van der Bijl P, van Rosendael AR, Kitslaar PH, Reiber JHC, Jukema JW, Leon MB, Ajmone Marsan N, Knuuti J, Bax JJ
Background: Pericoronary adipose tissue (PCAT) attenuation has been associated with coronary inflammation and can be evaluated with coronary computed tomography angiography. The aims of this study were to compare the PCAT attenuation across precursors of culprit and nonculprit lesions of patients with acute coronary syndrome versus stable coronary artery disease (CAD). Methods: In this case-control study, patients with suspected CAD who underwent coronary computed tomography angiography were inc... Abstract
BMC cancer, Volume 23, Issue 1, 2 1 2023, Pages 115 Cardiac and obstetric outcomes of pregnancies for women after cardiotoxic therapy in childhood: a single center observational study. Heemelaar JC, Heemelaar S, Hertel SN, Jukema JW, Sueters M, Louwerens M, Antoni ML
Background: Childhood cancer survivors (CCS) are at increased risk of cardiomyopathy during pregnancy if they have prior cardiotoxic exposure. Currently, there is no consensus on the necessity, timing and modality of cardiac monitoring during and after pregnancy. Therefore, we examined cardiac function using contemporary echocardiographic parameters during pregnancy in CCS with cardiotoxic treatment exposure, and we observed obstetric outcomes in CCS, including in women without previous cardioto... Abstract
Cited 2 times since 2023 (0.8 per year) source: EuropePMC
Life (Basel, Switzerland), Volume 13, Issue 2, 2 1 2023, Pages 428 Association of Circulating Neutrophils with Relative Volume of Lipid-Rich Necrotic Core of Coronary Plaques in Stable Patients: A Substudy of SMARTool European Project. Sbrana S, Cecchettini A, Bastiani L, Mazzone A, Vozzi F, Caselli C, Neglia D, Clemente A, Scholte AJHA, Parodi O, Pelosi G, Rocchiccioli S
Background and aims: Coronary atherosclerosis is a chronic non-resolving inflammatory process wherein the interaction of innate immune cells and platelets plays a major role. Circulating neutrophils, in particular, adhere to the activated endothelium and migrate into the vascular wall, promoting monocyte recruitment and influencing plaque phenotype and stability at all stages of its evolution. We aimed to evaluate, by flow cytometry, if blood neutrophil number and phenotype-including their pheno... Abstract
Cited 1 times since 2023 (0.4 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 10, 2 1 2023, Pages 1097201 Commentary: Transforming growth factor serum concentrations in patients with proven non-syndromic aortopathy. Grewal N, Klautz R, Poelmann RE
Cited 37 times since 2023 (15.6 per year) source: EuropePMC
Nature medicine, Volume 29, Issue 3, 2 1 2023, Pages 588-592 High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial. van Dorp J, Pipinikas C, Suelmann BBM, Mehra N, van Dijk N, Marsico G, van Montfoort ML, Hackinger S, Braaf LM, Amarante T, van Steenis C, McLay K, Daletzakis A, van den Broek D, van de Kamp MW, Hendricksen K, de Feijter JM, Boellaard TN, Meijer RP, van der Heijden AG, Rosenfeld N, van Rhijn BWG, Jones G, van der Heijden MS
Cohort 1 of the phase 1B NABUCCO trial showed high pathological complete response (pCR) rates with preoperative ipilimumab plus nivolumab in stage III urothelial cancer (UC). In cohort 2, the aim was dose adjustment to optimize responses. Additionally, we report secondary endpoints, including efficacy and tolerability, in cohort 2 and the association of presurgical absence of circulating tumor DNA (ctDNA) in urine and plasma with clinical outcome in both cohorts. Thirty patients received two cyc... Abstract
Cited 7 times since 2023 (2.9 per year) source: EuropePMC
Nature communications, Volume 14, Issue 1, 1 1 2023, Pages 544 Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response. Dekkers KF, Slieker RC, Ioan-Facsinay A, van Iterson M, BIOS consortium, Ikram MA, van Greevenbroek MMJ, Veldink JH, Franke L, Boomsma DI, Slagboom PE, Jukema JW, Heijmans BT
Immune cell function can be altered by lipids in circulation, a process potentially relevant to lipid-associated inflammatory diseases including atherosclerosis and rheumatoid arthritis. To gain further insight in the molecular changes involved, we here perform a transcriptome-wide association analysis of blood triglycerides, HDL cholesterol, and LDL cholesterol in 3229 individuals, followed by a systematic bidirectional Mendelian randomization analysis to assess the direction of effects and con... Abstract