6131 results
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
European biophysics journal : EBJ,
Volume 42, Issue 4, 23 4 2012, Pages 241-255
Depolarization-induced automaticity in rat ventricular cardiomyocytes is based on the gating properties of L-type calcium and slow Kv channels.
Ypey DL, van Meerwijk WP, Umar S, Pijnappels DA, Schalij MJ, van der Laarse A
Depolarization-induced automaticity (DIA) of cardiomyocytes is the property of those cells to generate pacemaker cell-like spontaneous electrical activity when subjected to a depolarizing current. This property provides a candidate mechanism for generation of pathogenic ectopy in cardiac tissue. The purpose of this study was to determine the biophysical mechanism of DIA in terms of the ion conductance properties of the cardiomyocyte membrane. First, we determined, by use of the conventional whol...
Abstract
Cited 4 times since 2012 (0.3 per year)
source: EuropePMC
Journal of plastic, reconstructive & aesthetic surgery : JPRAS,
Volume 66, Issue 1, 23 4 2012, Pages e26-8
Associated anomalies and diagnostic approach in lumbosacral and perineal haemangiomas: case report and review of the literature.
de Graaf M, Pasmans SG, van Drooge AM, Nievelstein RA, Gooskens RH, Raphael MF, Breugem CC
Abstract
Cited 30 times since 2012 (2.4 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 5, Issue 6, 22 4 2012, Pages 1059-1063
Prevalence and presentation of externalized conductors and electrical abnormalities in Riata defibrillator leads after fluoroscopic screening: report from the Netherlands Heart Rhythm Association Device Advisory Committee.
Theuns DA, Elvan A, de Voogt W, de Cock CC, van Erven L, Meine M
Background: The Riata family of implantable cardioverter-defibrillator (ICD) leads is prone to a specific insulation abrasion characterized by externalization of conductor cables. The objective of this study was to determine the prevalence of externalized conductors and electrical abnormalities in Riata ICD leads by fluoroscopic screening and standard ICD interrogation. Methods and results: All ICD implantation centers were contacted by the Netherlands Heart Rhythm Association Device Advisory Co...
Abstract
Cited 17 times since 2012 (1.4 per year)
source: EuropePMC
American heart journal,
Volume 164, Issue 5, 16 3 2012, Pages 771-778
Intramyocardial injection of bone marrow mononuclear cells in chronic myocardial ischemia patients after previous placebo injection improves myocardial perfusion and anginal symptoms: an intra-patient comparison.
Rodrigo SF, van Ramshorst J, Beeres SL, Al Younis I, Dibbets-Schneider P, de Roos A, Fibbe WE, Zwaginga JJ, Schalij MJ, Bax JJ, Atsma DE
Background: We recently demonstrated in a randomized, double-blind, placebo-controlled trial that intramyocardial bone marrow cell (BMC) injection is associated with improvements in myocardial perfusion and anginal symptoms in chronic myocardial ischemia patients. In the present study the results of the crossover phase of this trial, in which patients previously treated with placebo received autologous BMC injections are reported. This allows a unique intra-patient comparison on the effect of BM...
Abstract
Cited 2 times since 2012 (0.2 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 10, 16 3 2012, Pages e46356
Fractional flow reserve is not associated with inflammatory markers in patients with stable coronary artery disease.
Sels JW, Elsenberg EH, Hoefer IE, van Zonneveld AJ, Kuiper J, Jukema JW, Pijls NH, Pasterkamp G
Background: Atherosclerosis is an inflammatory condition and increased blood levels of inflammatory biomarkers have been observed in acute coronary syndromes. In addition, high expression of inflammatory markers is associated with worse prognosis of coronary artery disease. The presence and extent of inducible ischemia in patients with stable angina has previously been shown to have strong prognostic value. We hypothesized that evidence of inducible myocardial ischemia by local lesions, as measu...
Abstract
Cited 33 times since 2012 (2.7 per year)
source: EuropePMC
Cardiovascular research,
Volume 97, Issue 2, 14 2 2012, Pages 311-320
Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease.
de Vries MR, Wezel A, Schepers A, van Santbrink PJ, Woodruff TM, Niessen HW, Hamming JF, Kuiper J, Bot I, Quax PH
Aims: Failure of vein graft conduits due to vein graft thickening, accelerated atherosclerosis, and subsequent plaque rupture is applicable to 50% of all vein grafts within 10 years. New potential therapeutic targets to treat vein graft disease may be found in components of the innate immune system, such as mast cells and complement factors, which are known to be involved in atherosclerosis and plaque destabilization. Interestingly, mast cells can be activated by complement factor C5a and, there...
Abstract
Cited 51 times since 2012 (4.1 per year)
source: EuropePMC
Heart rhythm,
Volume 10, Issue 2, 13 2 2012, Pages 158-164
Electrophysiological characteristics of ventricular tachyarrhythmias in cardiac sarcoidosis versus arrhythmogenic right ventricular cardiomyopathy.
Dechering DG, Kochhäuser S, Wasmer K, Zellerhoff S, Pott C, Köbe J, Spieker T, Piers SR, Bittner A, Mönnig G, Breithardt G, Wichter T, Zeppenfeld K, Eckardt L
Background: Recent evidence suggests that cardiac sarcoidosis (CS) and arrhythmogenic right ventricular cardiomyopathy (ARVC) can manifest very similarly. Objective: To investigate whether there are significant demographic and electrophysiological differences between patients with CS and ARVC. Methods: We prospectively compared patients with proven CS or ARVC who underwent radiofrequency catheter ablation of ventricular tachycardias by using 3-dimensional electroanatomical mapping. Furthermore,...
Abstract
Cited 32 times since 2012 (2.6 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 10, 11 2 2012, Pages e46855
Risk of cardiovascular disease in a traditional African population with a high infectious load: a population-based study.
Koopman JJ, van Bodegom D, Jukema JW, Westendorp RG
Background: To test the inflammatory origin of cardiovascular disease, as opposed to its origin in western lifestyle. Population-based assessment of the prevalences of cardiovascular risk factors and cardiovascular disease in an inflammation-prone African population, including electrocardiography and ankle-arm index measurement. Comparison with known prevalences in American and European societies. Methodology/principal findings: Traditional population in rural Ghana, characterised by adverse env...
Abstract
Cited 34 times since 2012 (2.7 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 10, 11 2 2012, Pages e47134
Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression.
de Vries MR, Niessen HW, Löwik CW, Hamming JF, Jukema JW, Quax PH
The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that this model can be validated by overexpression of the MMP inhibitor TIMP-1. First we studied 47 vein grafts in hypercholesterolemic ApoE3*Leiden mice for the incidence of plaque complications. In 79% of these grafts, extensive lesions with plaque rup...
Abstract
Cited 11 times since 2012 (0.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 60, Issue 19, 10 2 2012, Pages 1991-1992
Does pregnancy influence the durability of human aortic valve substitutes?
Arabkhani B, Heuvelman HJ, Bogers AJ, Mokhles MM, Roos-Hesselink JW, Takkenberg JJ
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
Cardiology in the young,
Volume 23, Issue 4, 2 1 2012, Pages 540-545
Peri-operative care in adults with congenital heart disease: room for improvement in after care.
Schoormans D, Smets EM, Zwart R, Sprangers MA, Veelenturg TH, de Mol BA, Hazekamp MG, Koolbergen DR, Sojak V, Bouma BJ, Groenink M, Boekholdt MS, Backx AP, Mulder BJ
Background: Patient satisfaction with care has received little attention within the field of congenital heart disease. Our objective was to examine patient satisfaction with the care received when undergoing open-heart surgery in order to identify the best and worst aspects of peri-operative care. Moreover, we examined whether having contact with a specialised nurse in addition to usual care is associated with higher patient satisfaction levels. Methods: Patient satisfaction was measured by the...
Abstract
Expert review of cardiovascular therapy,
Volume 10, Issue 10, 1 1 2012, Pages 1197-1199
Primary prevention implantable cardioverter-defibrillator treatment: how to identify patients most likely to benefit?
Thijssen J, van Rees JB, Schalij MJ, Borleffs CJ
Abstract
Cited 8 times since 2012 (0.6 per year)
source: EuropePMC
Transplantation,
Volume 94, Issue 7, 1 1 2012, Pages 721-728
Late calcineurin inhibitor withdrawal prevents progressive left ventricular diastolic dysfunction in renal transplant recipients.
Mourer JS, Ewe SH, Mallat MJ, Ng AC, Rabelink TJ, Bax JJ, Delgado V, de Fijter JW
Background: Calcineurin inhibitor (CNI)-based therapy is associated with adverse cardiovascular effects. We examined the effects of late CNI or mycophenolate mofetil (MMF) withdrawal on echocardiographic parameters. Methods: This study was conducted as a substudy of a randomized trial in stable renal transplant recipients who were on a triple CNI-based regimen with prednisone and MMF that evaluated late concentration-controlled withdrawal of CNI or MMF on renal function. A total of 108 patients...
Abstract
Cited 6 times since 2012 (0.5 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 20, Issue 10, 1 1 2012, Pages 419-424
Prosthetic valves in adult patients with congenital heart disease: Rationale and design of the Dutch PROSTAVA study.
Freling HG, van Slooten YJ, van Melle JP, Mulder BJ, van Dijk AP, Hillege HL, Post MC, Sieswerda GT, Jongbloed MR, Willems TP, Pieper PG, PROSTAVA investigators
Background: Data on long-term complications in adult patients with congenital heart disease (ACHD) and a prosthetic valve are scarce. Moreover, the influence of prosthetic valves on quality of life (QoL) and functional outcome in ACHD patients with prosthetic valves has not been studied. Objectives: The primary objective of the PROSTAVA study is to investigate the relation between prosthetic valve characteristics (type, size and location) and functional outcome as well as QoL in ACHD patients. T...
Abstract
Cited 4 times since 2012 (0.3 per year)
source: EuropePMC
Journal of medical physics,
Volume 37, Issue 4, 1 1 2012, Pages 235-239
Radiotherapy pre-treatment dose validation: A second verification of monitor units (MU) with a commercial software.
Al Amri I, Ravichandran R, Sivakumar SS, Binukumar JP, Davis CA, Al Rahbi Z, Al Shukeili K, Al Kindi F
Inversely planned intensity-modulated radiotherapy (IMRT) and stereotactic small field radiotherapy should be verified before treatment execution. A second verification is carried out for planned treatments in IMRT and 3D conformal radiotherapy (3D-CRT) using a monitor verification commercial dose calculation management software (DCMS). For the same reference point the ion-chamber measured doses are compared for IMRT plans. DCMS (Diamond) computes dose based on modified Clarkson integration, acc...
Abstract
Cited 30 times since 2012 (2.4 per year)
source: EuropePMC
Journal of cellular and molecular medicine,
Volume 16, Issue 10, 1 1 2012, Pages 2440-2450
Shear induced collateral artery growth modulated by endoglin but not by ALK1.
Seghers L, de Vries MR, Pardali E, Hoefer IE, Hierck BP, ten Dijke P, Goumans MJ, Quax PH
Transforming growth factor-beta (TGF-β) stimulates both ischaemia induced angiogenesis and shear stress induced arteriogenesis by signalling through different receptors. How these receptors are involved in both these processes of blood flow recovery is not entirely clear. In this study the role of TGF-β receptors 1 and endoglin is assessed in neovascularization in mice. Unilateral femoral artery ligation was performed in mice heterozygous for either endoglin or ALK1 and in littermate controls. C...
Abstract
Cited 5 times since 2012 (0.4 per year)
source: EuropePMC
Lancet (London, England),
Volume 380, Issue 9852, 1 1 2012, Pages 1471-1472
Hypertension in developing countries.
Koopman JJ, van Bodegom D, Beenakker KG, Jukema JW, Westendorp RG
Abstract
Cited 16 times since 2012 (1.3 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 98, Issue 20, 1 1 2012, Pages 1529-1536
Late acquired stent malapposition: why, when and how to handle?
Karalis I, Ahmed TA, Jukema JW
Abstract
Cited 15 times since 2012 (1.2 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 29, Issue 3, 28 4 2012, Pages 609-616
Relationship between left ventricular diastolic function and arterial stiffness in asymptomatic patients with diabetes mellitus.
Roos CJ, Auger D, Djaberi R, de Koning EJ, Rabelink TJ, Pereira AM, Bax JJ, Delgado V, Jukema JW, Scholte AJ
Left ventricular (LV) diastolic dysfunction and increased arterial stiffness are common in patients with diabetes mellitus (DM). However, the relation between these two pathophysiological factors remains unclear. The aim of this study was to investigate the relationship between LV diastolic function and arterial stiffness as assessed with applanation tonometry. In 142 asymptomatic patients with DM (mean age 48 years, 75 (53 %) men, 72 (51 %) patients with type 2 DM) LV diastolic function was ass...
Abstract
Cited 148 times since 2012 (11.9 per year)
source: Scopus
European journal of preventive cardiology,
Volume 20, Issue 4, 28 4 2012, Pages 620-640
Lifestyle modification programmes for patients with coronary heart disease: a systematic review and meta-analysis of randomized controlled trials.
Janssen V, De Gucht V, Dusseldorp E, Maes S
Background: Lifestyle modification programmes for coronary heart disease patients have been shown to effectively improve risk factors and related health behaviours, quality of life, reincidence, and mortality. However, improvements in routine cardiac care over the recent years may offset the incremental benefit associated with older programmes. Purpose: To determine the efficacy of lifestyle modification programmes for coronary heart disease patients developed over the last decade (1999-2009) by...
Abstract
