6128 results
Cited 27 times since 2009 (1.8 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 30, Issue 3, 23 4 2009, Pages 605-611
Activation of hemostasis and decline in cognitive function in older people.
Stott DJ, Robertson M, Rumley A, Welsh P, Sattar N, Packard CJ, Shepherd J, Trompet S, Westendorp RG, de Craen AJ, Jukema JW, Buckley B, Ford I, Lowe GD
Objective: To determine whether activation of hemostatic function (thrombosis and fibrinolysis) is associated with cognitive decline in older people. Methods and results: We studied 5804 people (age, 70-82 years) in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Mean follow-up was 3.2 years, including annual measurement of speed of information processing (letter, digit coding, and Stroop), verbal memory (picture-word naming), and basic and instrumental activities of daily...
Abstract
Cited 6 times since 2009 (0.4 per year)
source: EuropePMC
Brain & development,
Volume 32, Issue 6, 23 4 2009, Pages 467-471
Tau proteins in the cerebrospinal fluid of patients with subacute sclerosing panencephalitis.
Yuksel D, Yilmaz D, Uyar NY, Senbil N, Gurer Y, Anlar B
Neurodegenerative diseases characterized by cytoskeletal deformation and neurofibrillary tangles are associated with altered levels of tau and related proteins in cerebrospinal fluid (CSF). Neuronal or glial fibrillary tangles have been shown in 20% of subacute sclerosing panencephalitis (SSPE) patients. We therefore investigated CSF samples from 60 newly diagnosed SSPE and 31 neurological control patients for total tau (t-tau), phosphorylated tau (p-tau), and S100-B levels by ELISA. There was n...
Abstract
Cited 18 times since 2009 (1.2 per year)
source: EuropePMC
Atherosclerosis,
Volume 210, Issue 2, 22 4 2009, Pages 596-601
Metabolic syndrome is an independent predictor of cardiovascular events in high-risk patients with occlusive and aneurysmatic peripheral arterial disease.
van Kuijk JP, Flu WJ, Chonchol M, Bax JJ, Verhagen HJ, Poldermans D
Objective: Metabolic syndrome (MetSyn) is a well-known risk factor for cardiovascular (CV) disease in the general population; however, the additional predictive value for CV events in high-risk patients with peripheral arterial disease (PAD) is unknown. The aims of the current study were to assess and compare: (1) prevalence of MetSyn, and (2) predictive value of MetSyn for CV events, in patients with either occlusive or aneurysmatic PAD. Methods: We screened 2069 patients scheduled for lower oc...
Abstract
Cited 12 times since 2009 (0.8 per year)
source: EuropePMC
The American journal of cardiology,
Volume 105, Issue 3, 21 3 2009, Pages 302-305
Diagnostic accuracy of 64-slice multislice computed tomographic coronary angiography in patients with an intermediate pretest likelihood for coronary artery disease.
van Werkhoven JM, Heijenbrok MW, Schuijf JD, Jukema JW, Boogers MM, van der Wall EE, Schreur JH, Bax JJ
Data on the diagnostic accuracy of multislice computed tomographic coronary angiography (CTA) have been mostly derived from patients with a high pretest likelihood of coronary artery disease. Systematic comparisons with invasive angiography in patients with an intermediate pretest likelihood are scarce. The purpose of the present study was to determine the diagnostic accuracy of CTA in patients without known coronary artery disease with an intermediate pretest likelihood. A total of 61 patients...
Abstract
Cited 224 times since 2009 (14.7 per year)
source: EuropePMC
Circulation,
Volume 121, Issue 1, 21 3 2009, Pages 80-90
Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody.
Arslan F, Smeets MB, O'Neill LA, Keogh B, McGuirk P, Timmers L, Tersteeg C, Hoefer IE, Doevendans PA, Pasterkamp G, de Kleijn DP
Background: Reperfusion therapy for myocardial infarction is hampered by detrimental inflammatory responses partly via Toll-like receptor (TLR) activation. Targeting TLR signaling may optimize reperfusion therapy and enhance cell survival and heart function after myocardial infarction. Here, we evaluated the role of TLR2 as a therapeutic target using a novel monoclonal anti-TLR2 antibody. Method and results: Mice underwent 30 minutes of ischemia followed by reperfusion. Compounds were administer...
Abstract
Cited 23 times since 2009 (1.5 per year)
source: EuropePMC
The American journal of cardiology,
Volume 105, Issue 3, 21 3 2009, Pages 306-311
Impact of left ventricular dyssynchrony early on left ventricular function after first acute myocardial infarction.
Nucifora G, Bertini M, Marsan NA, Delgado V, Scholte AJ, Ng AC, van Werkhoven JM, Siebelink HM, Holman ER, Schalij MJ, van der Wall EE, Bax JJ
The impact of left ventricular (LV) dyssynchrony after acute myocardial infarction (AMI) on LV ejection fraction (EF) is unknown. One hundred twenty-nine patients with a first ST-elevation AMI (58 + or - 11 years, 78% men) and QRS duration
Abstract
Cited 44 times since 2009 (2.9 per year)
source: EuropePMC
European heart journal,
Volume 31, Issue 7, 16 3 2009, Pages 842-848
The yield of risk stratification for sudden cardiac death in hypertrophic cardiomyopathy myosin-binding protein C gene mutation carriers: focus on predictive screening.
Christiaans I, Birnie E, van Langen IM, van Spaendonck-Zwarts KY, van Tintelen JP, van den Berg MP, Atsma DE, Helderman-van den Enden AT, Pinto YM, Hermans-van Ast JF, Bonsel GJ, Wilde AA
Aims: We investigated the presence of a clinical diagnosis of hypertrophic cardiomyopathy (HCM) and of risk factors for sudden cardiac death (SCD) at the first cardiological evaluation after predictive genetic testing in asymptomatic carriers of an MYBPC3 gene mutation. Methods and results: Two hundred and thirty-five mutation carriers were cardiologically evaluated on the presence of HCM and risk factors. A clinical diagnosis of HCM was made in 53 carriers (22.6%). Disease penetrance at 65 year...
Abstract
Cited 11 times since 2009 (0.7 per year)
source: EuropePMC
Respiratory medicine,
Volume 104, Issue 5, 14 2 2009, Pages 690-696
Co-existence of COPD and left ventricular dysfunction in vascular surgery patients.
Flu WJ, van Gestel YR, van Kuijk JP, Hoeks SE, Kuiper R, Verhagen HJ, Bax JJ, Sin DD, Poldermans D
Background: The co-existence between chronic obstructive pulmonary disease (COPD) and heart failure has been previously described. However, the co-existence between COPD and subclinical left ventricular (LV) dysfunction, without the presence of heart failure symptoms, is less well understood. This study determined the relationship and clinical relevance of COPD and subclinical LV dysfunction in vascular surgery patients. Methods: 1005 consecutive vascular surgery patients were included in which...
Abstract
Cited 4 times since 2009 (0.3 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 26, Issue 2, 12 2 2009, Pages 249-252
Fingertip digital thermal monitoring: a fingerprint for cardiovascular disease?
van der Wall EE, Schuijf JD, Bax JJ, Jukema JW, Schalij MJ
Abstract
Cited 78 times since 2009 (5.1 per year)
source: EuropePMC
American journal of respiratory and critical care medicine,
Volume 181, Issue 5, 3 1 2009, Pages 501-506
Patient outcomes after acute pulmonary embolism. A pooled survival analysis of different adverse events.
Klok FA, Zondag W, van Kralingen KW, van Dijk AP, Tamsma JT, Heyning FH, Vliegen HW, Huisman MV
Rationale: There is a lack of information on the long-term prognosis of patients with acute pulmonary embolism (PE). Objectives: To assess the long-term risk for adverse events after PE. Methods: Consecutive patients diagnosed with PE between January 2001 and July 2007, and patients in whom PE was ruled out from a previous study were followed until July 2008 for the occurrence of adverse clinical events: mortality, symptomatic recurrent venous thromboembolism, cancer, arterial cardiovascular eve...
Abstract
Cited 25 times since 2009 (1.6 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 17, Issue 2, 1 1 2009, Pages 225-231
Assessment of global left ventricular function and volumes with 320-row multidetector computed tomography: A comparison with 2D-echocardiography.
de Graaf FR, Schuijf JD, van Velzen JE, Nucifora G, Kroft LJ, de Roos A, Schalij MJ, Jukema JW, van der Wall EE, Bax JJ
Background: Multidetector computed tomography (MDCT) has been demonstrated as a feasible imaging modality for noninvasive assessment of coronary artery disease and left ventricular (LV) function. Recently, 320-row systems have become available with 16 cm anatomical coverage allowing image acquisition of the entire heart within a single heartbeat. The purpose of this study was to evaluate the accuracy of 320-row MDCT in the assessment of global LV function compared to two-dimensional (2D) echocar...
Abstract
Cited 2 times since 2009 (0.1 per year)
source: EuropePMC
Endocrine reviews,
Volume 30, Issue 7, 1 1 2009, Pages 927-928
Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach.
Welsh P, Polisecki E, Robertson M, Jahn S, Buckley BM, de Craen AJ, Ford I, Jukema JW, Macfarlane PW, Packard CJ, Stott DJ, Westendorp RG, Shepherd J, Hingorani AD, Smith GD, Schaefer E, Sattar N
Abstract
Cited 13 times since 2009 (0.9 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 33, Issue 4, 1 1 2009, Pages 431-436
Implementation of lead safety recommendations.
VAN Rees JB, Borleffs CJ, Bax JJ, Nagtegaal EM, VAN DER Velde ET, VAN Erven L, Schalij MJ
Background: The Medtronic Sprint Fidelis (SF) implantable cardioverter defibrillator (ICD; Medtronic Inc., Minneapolis, MN, USA) lead has a higher than expected failure rate. Because of patient safety, Medtronic announced two advisories consisting of (1) adjustments in device settings (October 2007) and (2) installation of a lead integrity algorithm (May 2008). The objective of this study was to evaluate the effect of Medtronic's announcements on patient safety. Methods: To comply with the...
Abstract
Cited 32 times since 2009 (2.1 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 2, Issue 12, 1 1 2009, Pages 1425-1435
Role of left ventricular twist mechanics in the assessment of cardiac dyssynchrony in heart failure.
Bertini M, Sengupta PP, Nucifora G, Delgado V, Ng AC, Marsan NA, Shanks M, van Bommel RJ, Schalij MJ, Narula J, Bax JJ
The authors discuss an incremental value of assessing left ventricular (LV) twist mechanics in patients with heart failure (HF) and its potential usefulness in characterizing response to cardiac resynchronization therapy (CRT) and reversal of LV remodeling at 6 months follow-up. They also underscore a critical relationship between LV lead position and changes in LV twist after CRT, and suggest that the reversal of LV remodeling in HF patients following CRT primarily results from restoration of t...
Abstract
Cited 4 times since 2009 (0.3 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 54, Issue 25, 1 1 2009, Pages 2447-2458
Highlights of the 2009 scientific sessions of the European Society of Cardiology.
Bax JJ, Casadei B, Di Mario C, Fagard R, Filippatos G, Fox KA, Metra M, Nihoyannopoulos P, Perk J, Rademakers F, Rosenhek R, Vardas PE, Pinto FJ, Ferrari R
Abstract
Cited 73 times since 2009 (4.8 per year)
source: EuropePMC
European heart journal,
Volume 30, Issue 24, 1 1 2009, Pages 3027-3036
Blunted frequency-dependent upregulation of cardiac output is related to impaired relaxation in diastolic heart failure.
Wachter R, Schmidt-Schweda S, Westermann D, Post H, Edelmann F, Kasner M, Lüers C, Steendijk P, Hasenfuss G, Tschöpe C, Pieske B
Aims: We tested the hypothesis that, in heart failure with normal ejection fraction (HFNEF), diastolic dysfunction is accentuated at increasing heart rates, and this contributes to impaired frequency-dependent augmentation of cardiac output. Methods and results: In 17 patients with HFNEF (median age 69 years, 13 female) and seven age-matched control patients, systolic and diastolic function was analysed by pressure-volume loops at baseline heart rate and during atrial pacing to 100 and 120 min(-...
Abstract
Cited 1 times since 2009 (0.1 per year)
source: EuropePMC
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists,
Volume 16, Issue 6, 1 1 2009, Pages 690-693
Remote ischemic preconditioning in vascular surgery patients: the additional value to medical treatment.
van Kuijk JP, Flu WJ, Verhagen HJ, Bax JJ, Poldermans D
Abstract
Cited 13 times since 2009 (0.9 per year)
source: EuropePMC
The American journal of cardiology,
Volume 104, Issue 11, 1 1 2009, Pages 1490-1493
Prognostic significance of QRS duration in patients with suspected coronary artery disease referred for noninvasive evaluation of myocardial ischemia.
Schinkel AF, Elhendy A, van Domburg RT, Biagini E, Rizzello V, Veltman CE, Ten Kate GL, Sijbrands EJ, Akkerhuis KM, Geleijnse ML, Ten Cate FJ, Simoons ML, Bax JJ, Poldermans D
The purpose of this study was to evaluate the prognostic significance of QRS duration in patients with suspected coronary artery disease (CAD) referred for noninvasive evaluation of myocardial ischemia by dobutamine stress echocardiography. QRS duration is a prognostic marker in patients with previous myocardial infarction and/or heart failure. The relation between QRS duration and outcome of patients without known heart disease has not been evaluated. A total of 1,227 patients (707 men, mean ag...
Abstract
Cited 144 times since 2009 (9.4 per year)
source: EuropePMC
European heart journal,
Volume 30, Issue 24, 1 1 2009, Pages 3037-3047
Strain analysis in patients with severe aortic stenosis and preserved left ventricular ejection fraction undergoing surgical valve replacement.
Delgado V, Tops LF, van Bommel RJ, van der Kley F, Marsan NA, Klautz RJ, Versteegh MI, Holman ER, Schalij MJ, Bax JJ
Aims: To evaluate myocardial multidirectional strain and strain rate (S-and-SR) in severe aortic stenosis (AS) patients with preserved left ventricular (LV) ejection fraction (EF), using two-dimensional speckle-tracking strain imaging (2D-STI). The long-term effect of aortic valve replacement (AVR) on S-and-SR was also evaluated. Methods and results: Changes in LV radial, circumferential, and longitudinal S-and-SR were evaluated in 73 severe AS patients (65 +/- 13 years; aortic valve area 0.8 +/...
Abstract
Cited 18 times since 2009 (1.2 per year)
source: EuropePMC
Respiratory medicine,
Volume 104, Issue 5, 25 4 2009, Pages 712-716
Association of COPD with carotid wall intima-media thickness in vascular surgery patients.
van Gestel YR, Flu WJ, van Kuijk JP, Hoeks SE, Bax JJ, Sin DD, Poldermans D
Introduction: There is increasing evidence that non-invasive imaging modalities such as ultrasonography may be able to detect subclinical atherosclerotic lesions, and as such may be useful tools for risk-stratification. However, the clinical relevance of these observations remains unknown in patients with COPD. Therefore we investigated the association between COPD and carotid wall intima-media thickness (IMT) in patients undergoing vascular surgery and its relationship with mortality in these p...
Abstract
