Research

Publications

Below you can find a list of our published research.

6128 results

Cited 89 times since 2009 (5.8 per year) source: EuropePMC

Investigative radiology, Volume 44, Issue 10, 1 1 2009, Pages 669-675 Flow assessment through four heart valves simultaneously using 3-dimensional 3-directional velocity-encoded magnetic resonance imaging with retrospective valve tracking in healthy volunteers and patients with valvular regurgitation. Roes SD, Hammer S, van der Geest RJ, Marsan NA, Bax JJ, Lamb HJ, Reiber JH, de Roos A, Westenberg JJ

Objectives: To validate 3-dimensional (3D) 3-directional velocity-encoded (VE) magnetic resonance imaging (MRI) for flow assessment through all 4 heart valves simultaneously with retrospective valve-tracking during off-line analysis in healthy volunteers and in patients with valvular regurgitation. Material and methods: Three-dimensional 3-directional VE MRI was performed in 22 healthy volunteers and in 29 patients with ischemic cardiomyopathy who were suspected of valvular regurgitation and net... Abstract

Cited 98 times since 2009 (6.4 per year) source: EuropePMC

European journal of heart failure, Volume 11, Issue 10, 1 1 2009, Pages 929-936 Independent relationship of left atrial size and mortality in patients with heart failure: an individual patient meta-analysis of longitudinal data (MeRGE Heart Failure). Rossi A, Temporelli PL, Quintana M, Dini FL, Ghio S, Hillis GS, Klein AL, Marsan NA, Prior DL, Yu CM, Poppe KK, Doughty RN, Whalley GA, MeRGE Heart Failure Collaborators

Aims: Left atrial (LA) size is considered a marker of poor prognosis in heart failure (HF) patients. Prior studies have recruited relatively few subjects limiting their power to adequately analyse the interaction between LA size, left ventricular (LV) systolic and diastolic function, and prognosis. Method and results: The MeRGE collaboration combines prospective data from 18 studies in HF patients. In this analysis of data from 1157 patients, the primary endpoint was death or hospitalization for... Abstract

Cited 18 times since 2009 (1.2 per year) source: EuropePMC

The American journal of cardiology, Volume 104, Issue 8, 1 1 2009, Pages 1041-1046 Usefulness of carotid intima-media thickness in patients with diabetes mellitus as a predictor of coronary artery disease. Djaberi R, Schuijf JD, de Koning EJ, Rabelink TJ, Smit JW, Kroft LJ, Pereira AM, Scholte AJ, Spaans M, Romijn JA, de Roos A, van der Wall EE, Jukema JW, Bax JJ

Identification of asymptomatic patients with diabetes mellitus (DM) at increased risk for coronary artery disease (CAD) remains a challenge. Carotid intima-media thickness (CIMT) has been proposed as a surrogate marker for CAD but only limited data are available. The purpose of the study was to evaluate the potential of CIMT for prediction of CAD in asymptomatic patients with DM. Prospectively, CIMT of the left and right common carotid arteries was assessed by B-mode ultrasound in 150 asymptomat... Abstract

Cited 34 times since 2009 (2.2 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 88, Issue 4, 1 1 2009, Pages 1131-1136 Open window thoracostomy treatment of empyema is accelerated by vacuum-assisted closure. Palmen M, van Breugel HN, Geskes GG, van Belle A, Swennen JM, Drijkoningen AH, van der Hulst RR, Maessen JG

Background: Recurrent thoracic empyema in the presence of residual lung tissue can be treated with an open window thoracostomy (OWT). Vacuum-assisted closure (VAC) of these large thoracic defects is a novel option. Methods: Nineteen patients with residual lung tissue received an OWT for treatment of recurrent thoracic empyema. In this retrospective case series, 8 patients (aged 58 +/- 20 years, all male) were treated conventionally, and 11 patients (aged 53 +/- 17 years, 8 male) were treated wit... Abstract

Cited 16 times since 2009 (1 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 88, Issue 4, 1 1 2009, Pages 1300-1305 The outflow tract in transposition of the great arteries: an anatomic and morphologic study. Lalezari S, Mahtab EA, Bartelings MM, Wisse LJ, Hazekamp MG, Gittenberger-de Groot AC

Background: Neoaortic root dilatation is observed after the arterial switch operation for transposition of the great arteries. Although structural differences in the vessel wall of these patients may be of influence, we hypothesize that a histomorphologic difference in composition and embedding of the fibrous annulus in transposition of the great arteries may play a role in neoaortic root dilatation. Methods: Two normal human hearts and two unoperated human hearts with transposition of the great... Abstract

Cited 14 times since 2009 (0.9 per year) source: EuropePMC

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 11, Issue 10, 1 1 2009, Pages 1255-1256 Left atrial size as a predictor of successful radiofrequency catheter ablation for atrial fibrillation. den Uijl DW, Bax JJ

Abstract

Cited 1 times since 2009 (0.1 per year) source: EuropePMC

Acta cardiologica, Volume 64, Issue 5, 1 1 2009, Pages 611-616 Post-intervention IVUS is not predictive for very late in-stent thrombosis in drug-eluting stents. Bergheanu SC, Van der Hoeven BL, Hassan AK, Dijkstra J, Rosendaal FR, Liem SS, Schalij MJ, Van der Bom JG, Jukema JW

Objectives: Stent thrombosis is a life-threatening complication associated with sudden death and acute myocardial infarction. Histopathologic studies have linked the occurrence of very late stent thrombosis in drug-eluting stents (DES) with delayed endothealisation and stent malapposition. Our aim was to investigate if late stent malapposition in DES could be predicted by immediate postintervention intra-vascular ultrasonography (IVUS). Methods and results: From our MISSION! database of 184 cons... Abstract

Cited 5 times since 2009 (0.3 per year) source: EuropePMC

Circulation. Arrhythmia and electrophysiology, Volume 2, Issue 5, 1 1 2009, Pages e28-30 Real-time integration of intracardiac echocardiography to facilitate atrial tachycardia ablation in a patient with a Senning baffle. den Uijl DW, Blom NA, Wijnmaalen AP, Bax JJ, Schalij MJ, Zeppenfeld K

Abstract

Cited 166 times since 2009 (10.8 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 54, Issue 16, 1 1 2009, Pages 1524-1532 Altered myocardial substrate metabolism and decreased diastolic function in nonischemic human diabetic cardiomyopathy: studies with cardiac positron emission tomography and magnetic resonance imaging. Rijzewijk LJ, van der Meer RW, Lamb HJ, de Jong HW, Lubberink M, Romijn JA, Bax JJ, de Roos A, Twisk JW, Heine RJ, Lammertsma AA, Smit JW, Diamant M

Objectives: This study was designed to evaluate myocardial substrate and high-energy phosphate (HEP) metabolism in asymptomatic men with well-controlled, uncomplicated type 2 diabetes with verified absence of cardiac ischemia, and age-matched control subjects, and to assess the association with myocardial function. Background: Metabolic abnormalities, particularly an excessive exposure of the heart to circulating nonesterified fatty acids and myocardial insulin resistance are considered importan... Abstract

The Journal of thoracic and cardiovascular surgery, Volume 140, Issue 1, 26 4 2009, Pages 240-241 Balloon sizing in surgical ventricular restoration: what volume are we targeting? ten Brinke EA, Klautz RJ, Steendijk P

Abstract

Cited 51 times since 2009 (3.3 per year) source: EuropePMC

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, Volume 12, Issue 9, 26 4 2009, Pages 862-867 Laparoscopic peritoneal lavage for perforated colonic diverticulitis: a systematic review. Toorenvliet BR, Swank H, Schoones JW, Hamming JF, Bemelman WA

Aim: This systematic review aimed to evaluate the efficacy, morbidity and mortality of laparoscopic peritoneal lavage for patients with perforated diverticulitis. Method: We searched PubMed, EMBASE, Web of Science, the Cochrane Library and CINAHL databases, Google Scholar and five major publisher websites without language restriction. All articles which reported the use of laparoscopic peritoneal lavage for patients with perforated diverticulitis were included. Results: Two prospective cohort st... Abstract

Cited 184 times since 2009 (11.9 per year) source: EuropePMC

The American journal of cardiology, Volume 104, Issue 10, 26 4 2009, Pages 1398-1401 Findings from left ventricular strain and strain rate imaging in asymptomatic patients with type 2 diabetes mellitus. Ng AC, Delgado V, Bertini M, van der Meer RW, Rijzewijk LJ, Shanks M, Nucifora G, Smit JW, Diamant M, Romijn JA, de Roos A, Leung DY, Lamb HJ, Bax JJ

Regional left ventricular (LV) myocardial functional changes in early diabetic cardiomyopathy have not been well documented. LV multidirectional strain and strain rate analyses by 2-dimensional speckle tracking were used to detect subtle myocardial dysfunction in 47 asymptomatic, male patients (age 57 +/- 6 years) with type 2 diabetes mellitus. The results were compared to those from 53 male controls matched by age, body mass index, and body surface area. No differences were found in the LV end-... Abstract

Cited 68 times since 2009 (4.4 per year) source: EuropePMC

American journal of physiology. Heart and circulatory physiology, Volume 297, Issue 5, 25 4 2009, Pages H1606-16 Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension. Umar S, de Visser YP, Steendijk P, Schutte CI, Laghmani el H, Wagenaar GT, Bax WH, Mantikou E, Pijnappels DA, Atsma DE, Schalij MJ, van der Wall EE, van der Laarse A

Pulmonary arterial hypertension (PAH) is a chronic lung disease that leads to right ventricular (RV) hypertrophy (RVH), remodeling, and failure. We tested treatment with bone marrow-derived mesenchymal stem cells (MSCs) obtained from donor rats with monocrotaline (MCT)-induced PAH to recipient rats with MCT-induced PAH on pulmonary artery pressure, lung pathology, and RV function. This model was chosen to mimic autologous MSC therapy. On day 1, PAH was induced by MCT (60 mg/kg) in 20 female Wist... Abstract

Cited 71 times since 2009 (4.6 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 26, Issue 1, 16 3 2009, Pages 57-64 Intra-observer and interobserver variability of biventricular function, volumes and mass in patients with congenital heart disease measured by CMR imaging. Luijnenburg SE, Robbers-Visser D, Moelker A, Vliegen HW, Mulder BJ, Helbing WA

Cardiovascular magnetic resonance (CMR) imaging provides highly accurate measurements of biventricular volumes and mass and is frequently used in the follow-up of patients with acquired and congenital heart disease (CHD). Data on reproducibility are limited in patients with CHD, while measurements should be reproducible, since CMR imaging has a main contribution to decision making and timing of (re)interventions. The aim of this study was to assess intra-observer and interobserver variability of... Abstract

Cited 6 times since 2009 (0.4 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 26, Issue 1, 16 3 2009, Pages 19-25 Limited value of digital subtraction angiography in the evaluation of cell-based therapy in patients with limb ischemia. van Tongeren RB, Hamming JF, le Cessie S, van Erkel AR, van Bockel JH

Cell-based therapy has been proposed as a novel strategy for patients with severe peripheral arterial disease by stimulating vascular growth. In clinical studies of this therapy, the emphasis has been on demonstrating recovery of clinical parameters, rather than on evaluation of blood flow recovery. Angiography is still the gold standard for the assessment of lower leg arteries. Therefore, we studied the usefulness of angiography in the evaluation of cell-based therapy. Sixteen patients with cri... Abstract

Cited 9 times since 2009 (0.6 per year) source: EuropePMC

Lung cancer (Amsterdam, Netherlands), Volume 69, Issue 1, 15 3 2009, Pages 60-65 EUS-FNA in the preoperative staging of non-small cell lung cancer. Talebian M, von Bartheld MB, Braun J, Versteegh MI, Dekkers OM, Rabe KF, Annema JT

Background: According to current guidelines, transesophageal ultrasound-guided fine needle aspiration (EUS-FNA) can be performed as an alternative for surgical staging to confirm mediastinal metastases in patients with non-small cell lung cancer (NSCLC). To date however, data regarding the routine use of EUS-FNA in the preoperative staging of unselected patients with NSCLC are limited. Aims and objectives: (1) To evaluate the diagnostic value of EUS-FNA in consecutive, patients with NSCLC regard... Abstract

Cited 32 times since 2009 (2.1 per year) source: EuropePMC

Journal of lipid research, Volume 51, Issue 5, 14 2 2009, Pages 1201-1207 Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly. Polisecki E, Peter I, Simon JS, Hegele RA, Robertson M, Ford I, Shepherd J, Packard C, Jukema JW, de Craen AJ, Westendorp RG, Buckley BM, Schaefer EJ, Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Investigators

Niemann-Pick C1-like 1 protein (NPC1L1) plays a critical role in intestinal cholesterol absorption. Our objective was to examine whether five variants (-133A>G, -18A>C, L272L, V1296V, and U3_28650A>G) at the NPC1L1 gene have effects on lipid levels, prevalence, and incidence of coronary heart disease (CHD) and lipid-lowering response to pravastatin. We studied 5,804 elderly participants from the PROSPER study, who were randomized to prava-statin 40 mg/day or placebo and were followed on... Abstract

Cited 265 times since 2009 (17.1 per year) source: EuropePMC

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 27, Issue 31, 14 2 2009, Pages 5195-5201 Real-time quantitative polymerase chain reaction detection of minimal residual disease by standardized WT1 assay to enhance risk stratification in acute myeloid leukemia: a European LeukemiaNet study. Cilloni D, Renneville A, Hermitte F, Hills RK, Daly S, Jovanovic JV, Gottardi E, Fava M, Schnittger S, Weiss T, Izzo B, Nomdedeu J, van der Heijden A, van der Reijden BA, Jansen JH, van der Velden VH, Ommen H, Preudhomme C, Saglio G, Grimwade D

Purpose: Risk stratification in acute myeloid leukemia (AML) is currently based on pretreatment characteristics. It remains to be established whether relapse risk can be better predicted through assessment of minimal residual disease (MRD). One proposed marker is the Wilms tumor gene WT1, which is overexpressed in most patients with AML, thus providing a putative target for immunotherapy, although in the absence of a standardized assay, its utility for MRD monitoring remains controversial. Patie... Abstract

Cited 8 times since 2009 (0.5 per year) source: EuropePMC

Pacing and clinical electrophysiology : PACE, Volume 32, Issue 11, 10 2 2009, Pages e18-20 Different mechanisms underlying consecutive, postoperative atrial tachyarrhythmias in a Fontan patient. De Groot NM, Blom N, Vd Wall EE, Schalij MJ

Introduction: Atrial tachyarrhythmias (AT) frequently develop later after a Fontan operation and can be successfully treated by ablative therapy. However, new arrhythmias often develop. Methods and results: Consecutive AT emerging in a Fontan patient were ablated using three-dimensional electro-anatomical mapping. During a 6-year period, nine different AT were ablated, including intraatrial reentrant AT (N=5), focal AT (N=3), and focal atrial fibrillation (N=1) originating from distinct right at... Abstract

Cited 25 times since 2009 (1.6 per year) source: EuropePMC

Acta physiologica (Oxford, England), Volume 198, Issue 1, 6 1 2009, Pages 37-46 Single-beat estimation of the left ventricular end-systolic pressure-volume relationship in patients with heart failure. ten Brinke EA, Klautz RJ, Verwey HF, van der Wall EE, Dion RA, Steendijk P

Aim: The end-systolic pressure-volume relationship (ESPVR) constructed from multiple pressure-volume (PV) loops acquired during load intervention is an established method to asses left ventricular (LV) contractility. We tested the accuracy of simplified single-beat (SB) ESPVR estimation in patients with severe heart failure. Methods: Nineteen heart failure patients (NYHA III-IV) scheduled for surgical ventricular restoration and/or restrictive mitral annuloplasty and 12 patients with normal LV f... Abstract