6125 results
Cited 20 times since 2002 (0.9 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 43, Issue 6, 1 1 2002, Pages 795-802
Sequential (201)Tl imaging and dobutamine echocardiography to enhance accuracy of predicting improved left ventricular ejection fraction after revascularization.
Bax JJ, Maddahi J, Poldermans D, Elhendy A, Cornel JH, Boersma E, Roelandt JR, Fioretti PM
Unlabelled: 201Tl imaging and dobutamine echocardiography (DE) can both identify viable myocardium. Prediction of functional outcome after revascularization remains suboptimal with either technique because of the relatively low specificity of (201)Tl and low sensitivity of DE. This study was undertaken to develop an optimal testing strategy for prediction of post-revascularization functional outcome. Methods: Seventy-three patients (mean [+/-SD] left ventricular ejection fraction [LVEF], 32% +/-...
Abstract
Cited 6 times since 2002 (0.3 per year)
source: EuropePMC
Critical care medicine,
Volume 30, Issue 6, 1 1 2002, Pages 1301-1305
Continuous on-line measurement of absolute left ventricular volume by transcardiac conductance: angiographic validation in sheep.
Staal EM, Steendijk P, Koning G, Dijkstra J, Jukema JW, Baan J
Objective: Validation of the transcardiac conductance method for continuous, on-line measurement of absolute left ventricular volume by comparison with biplane angiography. Design: Controlled, prospective animal study. Setting: Catheterization laboratory of the Leiden University Medical Center. Subjects: Six anesthetized sheep. Interventions: Subjects were studied at baseline, during infusion of dobutamine, and during volume loading and beta blockade. In a pilot experiment, a coronary artery was...
Abstract
Cited 21 times since 2002 (0.9 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 43, Issue 6, 1 1 2002, Pages 767-772
Prognostic value of dobutamine-atropine stress (99m)Tc-tetrofosmin myocardial perfusion SPECT in patients with known or suspected coronary artery disease.
Schinkel AF, Elhendy A, van Domburg RT, Bax JJ, Roelandt JR, Poldermans D
Unlabelled: 99mTc-Tetrofosmin is a recently introduced radioactive isotope for the assessment of myocardial perfusion. Data regarding the prognostic value of stress imaging using this isotope are scarce. The aim of this study was to assess the prognostic value of dobutamine-atropine (99m)Tc-tetrofosmin SPECT for the prediction of late cardiac events in patients with known or suspected coronary artery disease. Methods: A total of 721 consecutive patients with limited exercise capacity underwent d...
Abstract
Cited 9 times since 2002 (0.4 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 21, Issue 6, 1 1 2002, Pages 1123-1125
Repair of aorto-right ventricular tunnel with pulmonary stenosis and an anomalous origin of the left coronary artery.
Hruda J, Hazekamp MG, Sobotka-Plojhar MA, Ottenkamp J
A 5-month-old infant with aorto-right ventricular tunnel, pulmonary stenosis and a sole supply of the left coronary artery from the tunnel underwent closure of the ventricular end of the tunnel, subsequent to balloon pulmonary valvuloplasty. Care was taken not to obstruct the aortic end of the tunnel in order to maintain the left coronary artery perfusion.
Abstract
Cited 26 times since 2002 (1.1 per year)
source: EuropePMC
Current controlled trials in cardiovascular medicine,
Volume 3, Issue 1, 20 3 2002, Pages 8
A Prospective Study of Pravastatin in the Elderly at Risk (PROSPER): Screening Experience and Baseline Characteristics.
Ford I, Blauw GJ, Murphy MB, Shepherd J, Cobbe SM, Bollen EL, Buckley BM, Jukema JW, Hyland M, Gaw A, Lagaay AM, Perry IJ, Macfarlane P, Norrie J, Meinders AE, Sweeney BJ, Packard CJ, Westendorp RG, Twomey C, Stott DJ, The PROSPER Study Group
BACKGROUND: PROSPER was designed to investigate the benefits of treatment with pravastatin in elderly patients for whom a typical doctor might consider the prescription of statin therapy to be a realistic option. METHODS: The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) is a randomised, double blind, placebo-controlled trial to test the hypothesis that treatment with pravastatin (40 mg/day) will reduce the risk of coronary heart disease death, non-fatal myocardial infarction...
Abstract
Cited 9 times since 2002 (0.4 per year)
source: EuropePMC
European radiology,
Volume 12 Suppl 3, 14 2 2002, Pages S177-80
Detection of malignant right coronary artery anomaly by multi-slice CT coronary angiography.
Dirksen MS, Bax JJ, Blom NA, Schalij MJ, Jukema WJ, Vliegen HW, van der Wall EE, de Roos A, Lamb HJ
Coronary artery anomalies occur in 0.3-0.8% of the population and infer a high risk for sudden cardiac death in young adults. Diagnosis is usually established during coronary angiography, which is hampered by poor spatial visualization. Magnetic resonance imaging is an alternative, but it is not feasible in the presence of metal objects or claustrophobia. In this report, a 15-year-old boy experienced ventricular fibrillation and was successfully resuscitated. Cardiac catheterization was inconclu...
Abstract
Cited 66 times since 2002 (2.9 per year)
source: EuropePMC
Diabetes care,
Volume 25, Issue 5, 1 1 2002, Pages 906-911
Impact of simultaneous pancreas and kidney transplantation on progression of coronary atherosclerosis in patients with end-stage renal failure due to type 1 diabetes.
Jukema JW, Smets YF, van der Pijl JW, Zwinderman AH, Vliegen HW, Ringers J, Reiber JH, Lemkes HH, van der Wall EE, de Fijter JW
Objective: Mortality in type 1 diabetic patients with end-stage renal failure is high and dominated by coronary atherosclerotic events. With regard to prognosis, simultaneous transplantation of pancreas and kidney (SPK) may be superior to kidney transplantation alone (KTA) in type 1 diabetic patients, because normalization of blood glucose levels may reduce progression of coronary atherosclerosis and because it is well known that progression of coronary atherosclerosis is one of the major factor...
Abstract
Cited 13 times since 2002 (0.6 per year)
source: EuropePMC
The American journal of cardiology,
Volume 89, Issue 10, 1 1 2002, Pages 1171-1175
Assessment of viable tissue in Q-wave regions by metabolic imaging using single-photon emission computed tomography in ischemic cardiomyopathy.
Schinkel AF, Bax JJ, Elhendy A, Boersma E, Vourvouri EC, Sozzi FB, Valkema R, Roelandt JR, Poldermans D
Chronic electrocardiographic Q waves are often believed to reflect irreversibly scarred, transmurally infarcted myocardium. The aim of this study was to evaluate whether residual viable tissue persists in dysfunctional myocardial regions related to chronic Q waves on the surface electrocardiogram. A total of 148 patients with healed myocardial infarction and impaired left ventricular (LV) function with heart failure symptoms underwent electrocardiography and metabolic imaging using technetium (T...
Abstract
Cited 13 times since 2002 (0.6 per year)
source: EuropePMC
Cardiology in the young,
Volume 12, Issue 3, 1 1 2002, Pages 266-271
Disease-related difficulties and satisfaction with level of knowledge in adults with mild or complex congenital heart disease.
Kamphuis M, Verloove-Vanhorick SP, Vogels T, Ottenkamp J, Vliegen HW
Objectives: To evaluate difficulties in daily life, and satisfaction with level of knowledge about their disease, in patients with congenital cardiac disease in order to improve counselling. Methods: A self-administered questionnaire was completed by 80 patients with mild, and 76 with complex, congenital cardiac disease. They were aged from 17 to 32 years. Results: Even patients with only mild malformations experienced difficulties related to their disease, but being found in only 11%, these wer...
Abstract
Cited 13 times since 2002 (0.6 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 23, Issue 5, 1 1 2002, Pages 393-397
The additional value of angiography after colour-coded duplex on decision making in patients with critical limb ischaemia. A prospective study.
Avenarius JK, Breek JC, Lampmann LE, van Berge Henegouwen DP, Hamming JF
Objective: to investigate prospectively the additional value of intra arterial digital subtraction arteriography (IADSA) for decision making in patients with critical limb ischemia (CLI). Treatment plans based on colour-duplex imaging (CDI) were compared with treatment plans based on IADSA. Methods: ninety-eight consecutive patients with 112 legs with CLI were investigated by CDI and IADSA. Treatment plans based on CDI and IADSA were made separately during a multidisciplinary meeting. Both plans...
Abstract
Cited 116 times since 2002 (5.1 per year)
source: EuropePMC
Journal of virology,
Volume 76, Issue 9, 1 1 2002, Pages 4612-4620
Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease.
Havenga MJ, Lemckert AA, Ophorst OJ, van Meijer M, Germeraad WT, Grimbergen J, van Den Doel MA, Vogels R, van Deutekom J, Janson AA, de Bruijn JD, Uytdehaag F, Quax PH, Logtenberg T, Mehtali M, Bout A
Since targeting of recombinant adenovirus vectors to defined cell types in vivo is a major challenge in gene therapy and vaccinology, we explored the natural diversity in human adenovirus tissue tropism. Hereto, we constructed a library of Ad5 vectors carrying fibers from other human serotypes. From this library, we identified vectors that efficiently infect human cells that are important for diverse gene therapy approaches and for induction of immunity. For several medical applications (prenata...
Abstract
Cited 54 times since 2002 (2.4 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 13, Issue 5, 1 1 2002, Pages 417-423
Long-term follow-up after radiofrequency catheter ablation of ventricular tachycardia: a successful approach?
Borger van der Burg AE, de Groot NM, van Erven L, Bootsma M, van der Wall EE, Schalij MJ
Introduction: Radiofrequency ablation (RFCA) of ventricular tachycardia (VT) is a potential curative treatment modality. We evaluated the results of RFCA in patients with VT. Methods and results: One hundred fifty-one consecutive patients (122 men and 29 women; age 57 +/- 16 years) with drug-refractory VT were treated. Underlying heart disease was ischemic heart disease in 89 (59%), arrhythmogenic right ventricular cardiomyopathy (ARVC) in 32 (21%), and idiopathic VT in 30 (20%; left ventricle i...
Abstract
Cited 20 times since 2002 (0.9 per year)
source: EuropePMC
Atherosclerosis,
Volume 162, Issue 1, 1 1 2002, Pages 103-110
VLDL receptor deficiency enhances intimal thickening after vascular injury but does not affect atherosclerotic lesion area.
Tacken PJ, Delsing DJ, Gijbels MJ, Quax PH, Havekes LM, Hofker MH, van Dijk KW
The very low density lipoprotein receptor (VLDLR) has been shown to modulate cell migration and foam cell formation in vitro. This suggests a role for the VLDLR in vascular pathology associated with intimal thickening and atherogenesis. In the present paper both intimal thickening and atherosclerosis were studied using VLDLR knockout and transgenic mouse models. The role of the VLDLR in intimal thickening was established in an in vivo model for vascular injury. A non-restrictive cuff was placed...
Abstract
Cited 22 times since 2002 (1 per year)
source: EuropePMC
Circulation research,
Volume 90, Issue 10, 1 1 2002, Pages 1128-1134
Adenoviral activin a expression prevents intimal hyperplasia in human and murine blood vessels by maintaining the contractile smooth muscle cell phenotype.
Engelse MA, Lardenoye JH, Neele JM, Grimbergen JM, De Vries MR, Lamfers ML, Pannekoek H, Quax PH, De Vries CJ
Activin A alters the characteristics of human arterial smooth muscle cells (SMCs) toward a contractile, quiescent phenotype. We hypothesize that activin A may prevent SMC-rich neointimal hyperplasia. Here, we study the effect of adenovirus-mediated expression of activin A on neointima formation in vitro and in vivo. Human saphenous vein organ cultures, in which a neointima is formed spontaneously, were infected either with activin A- or lacZ-adenovirus. Activin A-overexpression reduces neointima...
Abstract
Cited 15 times since 2002 (0.7 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 29, Issue 6, 10 2 2002, Pages 721-727
Accuracy of PET in predicting functional recovery after revascularisation in patients with chronic ischaemic dysfunction: head-to-head comparison between blood flow, glucose utilisation and water-perfusable tissue fraction.
Bax JJ, Fath-Ordoubadi F, Boersma E, Wijns W, Camici PG
Accurate prediction of improvement in left ventricular ejection fraction (LVEF) after revascularisation is critical in the therapeutic decision-making process in patients with chronic ischaemic dysfunction. Positron emission tomography (PET) allows non-invasive evaluation of myocardial blood flow (MBF), metabolic rate of glucose (MRG, absolute and relative) and the water-perfusable tissue fraction (PTF). Each of these indices has been proposed for the prediction of functional recovery. Their rel...
Abstract
Cited 26 times since 2002 (1.1 per year)
source: EuropePMC
The American journal of cardiology,
Volume 89, Issue 8, 1 1 2002, Pages 964-968
Prediction of mortality in heart transplant recipients by stress technetium-99m tetrofosmin myocardial perfusion imaging.
Elhendy A, van Domburg RT, Vantrimpont P, Poldermans D, Bax JJ, van Gelder T, Baan CC, Schinkel A, Roelandt JR, Balk AH
Cardiac allograft vasculopathy is a major cause of mortality in heart transplant recipients. The aim of this study was to assess the prognostic value of stress myocardial perfusion imaging in heart transplant recipients. We studied 166 patients (age 54 +/- 10 years, 140 men) by symptom-limited bicycle exercise or dobutamine (up to 40 microg/kg/min) stress myocardial perfusion imaging 7.4 +/- 2.5 years after heart transplantation. An intravenous dose of 370 MBq of technetium-99m tetrofosmin was i...
Abstract
Cited 11 times since 2002 (0.5 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 123, Issue 4, 1 1 2002, Pages 826-828
Carotid artery patch plasty as a last resort repair for long-segment congenital tracheal stenosis.
Dodge-Khatami A, Nijdam NC, Broekhuis E, Von Rosenstiel IA, Dahlem PG, Hazekamp MG
Abstract
Cited 97 times since 2002 (4.2 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 87, Issue 4, 1 1 2002, Pages 356-362
Health related quality of life and health status in adult survivors with previously operated complex congenital heart disease.
Kamphuis M, Ottenkamp J, Vliegen HW, Vogels T, Zwinderman KH, Kamphuis RP, Verloove-Vanhorick SP
Objective: To examine the impact of previously operated complex congenital heart disease on health related quality of life and subjective health status and to determine the relation between these parameters and physical status. Design: Cross sectional; information on medical follow up was sought retrospectively. Setting: Patients were randomly selected from the archives of the paediatric cardiology department, Leiden University Medical Centre, Leiden, The Netherlands, and approached irrespective...
Abstract
Cited 69 times since 2002 (3 per year)
source: EuropePMC
Radiology,
Volume 223, Issue 1, 1 1 2002, Pages 204-211
Exercise MR imaging in the assessment of pulmonary regurgitation and biventricular function in patients after tetralogy of fallot repair.
Roest AA, Helbing WA, Kunz P, van den Aardweg JG, Lamb HJ, Vliegen HW, van der Wall EE, de Roos A
Purpose: To assess the responses of pulmonary regurgitation (PR) and biventricular function to submaximal exercise by using a magnetic resonance (MR) imaging exercise protocol with young adult patients who underwent tetralogy of Fallot repair at a young age. Materials and methods: Fifteen patients with corrected tetralogy of Fallot (mean age, 17.5 years +/- 2.5 [SD]) underwent MR imaging at rest and during exercise for the evaluation of PR and biventricular function. Results were compared with f...
Abstract
Cited 70 times since 2002 (3.1 per year)
source: EuropePMC
American journal of physiology. Heart and circulatory physiology,
Volume 282, Issue 4, 1 1 2002, Pages H1350-8
Indexes of diastolic RV function: load dependence and changes after chronic RV pressure overload in lambs.
Leeuwenburgh BP, Steendijk P, Helbing WA, Baan J
Diastolic function is a major determinant of ventricular performance, especially when loading conditions are altered. We evaluated biventricular diastolic function in lambs and studied possible load dependence of diastolic parameters [minimum first derivative of pressure vs. time (dP/dt(min)) and time constant of isovolumic relaxation (tau)] in normal (n = 5) and chronic right ventricular (RV) pressure-overloaded (n = 5) hearts by using an adjustable band on the pulmonary artery (PAB). Pressure-...
Abstract
