7971 results
Cited 5032 times since 2021 (1162.6 per year)
source: EuropePMC
European heart journal,
Volume 42, Issue 5, 1 1 2021, Pages 373-498
2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC.
Hindricks G, Potpara T, Dagres N, Arbelo E, Bax JJ, Blomström-Lundqvist C, Boriani G, Castella M, Dan GA, Dilaveris PE, Fauchier L, Filippatos G, Kalman JM, La Meir M, Lane DA, Lebeau JP, Lettino M, Lip GYH, Pinto FJ, Thomas GN, Valgimigli M, Van Gelder IC, Van Putte BP, Watkins CL, ESC Scientific Document Group
Abstract
Cited 86 times since 2021 (19.9 per year)
source: EuropePMC
The Journal of infectious diseases,
Volume 223, Issue 2, 1 1 2021, Pages 214-224
Complement Activation in the Disease Course of Coronavirus Disease 2019 and Its Effects on Clinical Outcomes.
de Nooijer AH, Grondman I, Janssen NAF, Netea MG, Willems L, van de Veerdonk FL, Giamarellos-Bourboulis EJ, Toonen EJM, Joosten LAB, RCI-COVID-19 study group
Background: Excessive activation of immune responses in coronavirus disease 2019 (COVID-19) is considered to be related to disease severity, complications, and mortality rate. The complement system is an important component of innate immunity and can stimulate inflammation, but its role in COVID-19 is unknown. Methods: A prospective, longitudinal, single center study was performed in hospitalized patients with COVID-19. Plasma concentrations of complement factors C3a, C3c, and terminal complemen...
Abstract
Cited 10 times since 2021 (2.3 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 28, Issue 3, 31 5 2021, Pages 1105-1116
Assessing myocardial perfusion in suspected coronary artery disease: rationale and design of the second phase 3, open-label multi-center study of flurpiridaz (F-18) injection for positron emission tomography (PET) imaging.
Bourque JM, Hanson CA, Agostini D, Bateman TM, Bax JJ, Beanlands RSB, Berman DS, Garcia EV, Heller GV, Knuuti J, Tamaki N, Udelson JE, Maddahi J
Background: Positron emission tomography (PET) myocardial perfusion imaging (MPI) with the novel radiopharmaceutical Fluorine-18 Flurpiridaz has been shown in Phase 1, 2, and first Phase 3 clinical studies to be safe and effective in diagnosing coronary artery disease (CAD). We describe the methodology of the second FDA-mandated phase 3 prospective, open-label, international, multi-center trial of F-18 Flurpiridaz PET MPI. Methods: The primary study end point is to assess the diagnostic efficacy...
Abstract
Animals : an open access journal from MDPI,
Volume 11, Issue 2, 29 5 2021, Pages 347
Observational Study on Variation of Longitudinal Platelet Counts in Calves over the First 14 Days of Life and Reference Intervals from Cross-Sectional Platelet and Leukocyte Counts in Dairy Calves up to Two Months of Age.
Strous E, Vanhoudt A, Smolenaars A, van Schaik G, Schouten M, de Pater H, Roelofs B, Nielen M
Platelet and leukocyte count reference intervals (RIs) for cattle differ by age and while adult RIs are known, RIs for calves are studied less. The aims of this observational study are to evaluate variation of platelet counts of Holstein Friesian calves over the first 14 days of life and to propose RIs for platelet and leukocyte counts of Holstein Friesian calves aged 0-60 days. In a longitudinal study, 19 calves were blood sampled 17 times, in the first 14 days of their lives. Blood was collect...
Abstract
Cited 13 times since 2021 (3 per year)
source: EuropePMC
Evolutionary applications,
Volume 14, Issue 4, 29 5 2021, Pages 1124-1144
The ghosts of propagation past: haplotype information clarifies the relative influence of stocking history and phylogeographic processes on contemporary population structure of walleye (<i>Sander vitreus</i>).
Bootsma ML, Miller L, Sass GG, Euclide PT, Larson WA
Stocking of fish is an important tool for maintaining fisheries but can also significantly alter population genetic structure and erode the portfolio of within-species diversity that is important for promoting resilience and adaptability. Walleye (Sander vitreus) are a highly valued sportfish in the midwestern United States, a region characterized by postglacial recolonization from multiple lineages and an extensive history of stocking. We leveraged genomic data and recently developed analytical...
Abstract
Cited 33 times since 2021 (7.6 per year)
source: Scopus
EClinicalMedicine,
Volume 32, 28 4 2021, Pages 100731
Short-term outpatient follow-up of COVID-19 patients: A multidisciplinary approach.
de Graaf MA, Antoni ML, Ter Kuile MM, Arbous MS, Duinisveld AJF, Feltkamp MCW, Groeneveld GH, Hinnen SCH, Janssen VR, Lijfering WM, Omara S, Postmus PE, Ramai SRS, Rius-Ottenheim N, Schalij MJ, Schiemanck SK, Smid L, Stöger JL, Visser LG, de Vries JJC, Wijngaarden MA, Geelhoed JJM, Roukens AHE
Background: Short-term follow-up of COVID-19 patients reveals pulmonary dysfunction, myocardial damage and severe psychological distress. Little is known of the burden of these sequelae, and there are no clear recommendations for follow-up of COVID-19 patients.In this multi-disciplinary evaluation, cardiopulmonary function and psychological impairment after hospitalization for COVID-19 are mapped. Methods: We evaluated patients at our outpatient clinic 6 weeks after discharge. Cardiopulmonary fu...
Abstract
Cited 12 times since 2021 (2.8 per year)
source: EuropePMC
Journal of medical microbiology,
Volume 70, Issue 3, 28 4 2021
Emergence of carbapenem-resistant <i>Klebsiella pneumoniae</i> harbouring <i>bla</i> <sub>OXA-48</sub>-like genes in China.
Chen Y, Fang L, Yang Y, Yan R, Fu Y, Shen P, Zhao D, Chen Y, Hua X, Jiang Y, Moran RA, van Schaik W, Yu Y
Klebsiella pneumoniae strains carrying OXA-48-like carbapenemases are increasingly prevalent across the globe. There is thus an urgent need to better understand the mechanisms that underpin the dissemination of bla OXA-48-like carbapenemases. To this end, four ertapenem-resistant K. pneumoniae isolates producing OXA-48-like carbapenemases were isolated from two patients. Genome sequencing revealed that one sequence type (ST) 17 isolate carried bla OXA-181, whilst three isolates from a single pat...
Abstract
Cited 1 times since 2021 (0.2 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 37, Issue 5, 27 4 2021, Pages 1563-1565
Pacemaker lead-induced tricuspid regurgitation: consider leaflet remodeling.
Fortuni F, van der Kley F, Delgado V, Ajmone Marsan N
Abstract
Cited 16 times since 2021 (3.7 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 8, Issue 2, 27 4 2021, Pages 12
A Systematic Histopathologic Evaluation of Type-A Aortic Dissections Implies a Uniform Multiple-Hit Causation.
Grewal N, Velders BJJ, Gittenberger-de Groot AC, Poelmann R, Klautz RJM, Van Brakel TJ, Lindeman JHN
(1) Background: The pathophysiologic basis of an acute type A aortic dissection (TAAD) is largely unknown. In an effort to evaluate vessel wall defects, we systematically studied aortic specimens in TAAD patients. (2) Methods: Ascending aortic wall specimens (n = 58, mean age 63 years) with TAAD were collected. Autopsy tissues (n = 17, mean age 63 years) served as controls. All sections were studied histopathologically. (3) Results: Pathomorphology in TAAD showed predominantly moderate elastic f...
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
Pediatric pulmonology,
Volume 56, Issue 5, 26 4 2021, Pages 1053-1059
Point of care diaphragm ultrasound in acute bronchiolitis: A measurable tool to predict the clinical, sonographic severity of the disease, and outcomes.
Şık N, Çitlenbik H, Öztürk A, Yılmaz D, Duman M
Background: The aim of this study was to evaluate diaphragmatic parameters in bronchiolitis patients and identify correlations between clinical and sonographic severity scores and outcomes to develop a more objective and useful tool in the emergency department. Methods: Children aged between 1 and 24 months and diagnosed with acute bronchiolitis were included in the study. The Modified Respiratory Distress Assessment Instrument (mRDAI) score was used to quantify the clinical severity of the dise...
Abstract
Cited 30 times since 2021 (6.9 per year)
source: EuropePMC
International journal of obesity (2005),
Volume 45, Issue 3, 25 4 2021, Pages 687-694
A higher BMI is not associated with a different immune response and disease course in critically ill COVID-19 patients.
Kooistra EJ, de Nooijer AH, Claassen WJ, Grondman I, Janssen NAF, Netea MG, van de Veerdonk FL, van der Hoeven JG, Kox M, Pickkers P, RCI-COVID-19 study group
Background/objectives: Obesity appears to be an independent risk factor for ICU admission and a severe disease course in COVID-19 patients. An aberrant inflammatory response and impaired respiratory function have been suggested as underlying mechanisms. We investigated whether obesity is associated with differences in inflammatory, respiratory, and clinical outcome parameters in critically ill COVID-19 patients. Subjects/methods: Sixty-seven COVID-19 ICU patients were divided into obese (BMI ≥ 3...
Abstract
Cited 3 times since 2021 (0.7 per year)
source: EuropePMC
Cureus,
Volume 13, Issue 1, 23 4 2021, Pages e12877
Relationship Between Pituitary Siderosis and Endocrinological Disorders in Pediatric Patients with Beta-Thalassemia.
Yılmaz K, Kan A, Çetincakmak MG, Uzel VH, Yılmaz D, Deniz MA, Hattapoglu S
Introduction Excess iron accumulation occurs mainly in organs such as reticuloendothelial cells, the pituitary gland, and the pancreas in beta-thalassemia because of blood transfusions. In the present study, it was aimed to investigate the relationship between T2* values on magnetic resonance imaging (MRI) and clinically diagnosed pituitary endocrinological disorders in children with thalassemia major. Methods This study enrolled patients diagnosed with beta-thalassemia at pediatric hematology o...
Abstract
Cited 12 times since 2021 (2.8 per year)
source: EuropePMC
Diabetes, obesity & metabolism,
Volume 23, Issue 5, 22 4 2021, Pages 1084-1091
Prediction of mortality and major cardiovascular complications in type 2 diabetes: External validation of UK Prospective Diabetes Study outcomes model version 2 in two European observational cohorts.
Pagano E, Konings SRA, Di Cuonzo D, Rosato R, Bruno G, van der Heijden AA, Beulens J, Slieker R, Leal J, Feenstra TL
Aim: To externally validate the UK Prospective Diabetes Study Outcomes Model version 2 (UKPDS-OM2) by comparing the predicted and observed outcomes in two European population-based cohorts of people with type 2 diabetes. Materials and methods: We used data from the Casale Monferrato Survey (CMS; n = 1931) and a subgroup of the Hoorn Diabetes Care System (DCS) cohort (n = 5188). The following outcomes were analysed: all-cause mortality, myocardial infarction (MI), ischaemic heart disease (IHD), s...
Abstract
Cited 18 times since 2021 (4.1 per year)
source: EuropePMC
Appetite,
Volume 161, 22 4 2021, Pages 105135
Healthy eating beliefs and the meaning of food in populations with a low socioeconomic position: A scoping review.
van der Heijden A, Te Molder H, Jager G, Mulder BC
Profound understanding of healthy eating beliefs in populations with a low socioeconomic position (SEP) can benefit attempts to improve diet quality in this population, but literature on this subject is fragmented. The purpose of this scoping review was to systematically map healthy eating beliefs and the meaning of food and eating in populations with a low SEP. Systematic search of electronic databases yielded 35 relevant publications that were included in a qualitative synthesis. Populations w...
Abstract
Cited 126 times since 2021 (28.9 per year)
source: EuropePMC
Lancet (London, England),
Volume 397, Issue 10272, 21 3 2021, Pages 387-397
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries.
GlobalSurg Collaborative and National Institute for Health Research Global Health Research Unit on Global Surgery
Background: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for...
Abstract
Cited 1 times since 2021 (0.2 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 29, Issue 4, 20 3 2021, Pages 1534-1536
Diastolic dyssynchrony by SPECT: A novel parameter to predict post-infarct adverse remodeling.
van der Bijl P, Delgado V, Bax JJ
Abstract
Cited 10 times since 2021 (2.3 per year)
source: EuropePMC
Cancers,
Volume 13, Issue 3, 20 3 2021, Pages 377
Long-Term Experience with Radiofrequency-Induced Hyperthermia Combined with Intravesical Chemotherapy for Non-Muscle Invasive Bladder Cancer.
Brummelhuis ISG, Wimper Y, Witjes-van Os HGJM, Arends TJH, van der Heijden AG, Witjes JA
Background: The recurrence rate of non-muscle invasive bladder cancer (NMIBC) is high, despite intravesical treatments. Importantly, patients are frequently unfit or unwilling to undergo a recommended radical cystectomy when standard intravesical treatments fail, due to the substantial risk of morbidity and mortality. For these patients, radiofrequency-induced hyperthermia combined with intravesical chemotherapy (RF-CHT) has shown promising results. We aim to determine treatment outcomes and ass...
Abstract
Cited 27 times since 2021 (6.2 per year)
source: EuropePMC
Gastroenterology,
Volume 160, Issue 6, 19 3 2021, Pages 1970-1985
Healthy Cotwins Share Gut Microbiome Signatures With Their Inflammatory Bowel Disease Twins and Unrelated Patients.
Brand EC, Klaassen MAY, Gacesa R, Vich Vila A, Ghosh H, de Zoete MR, Boomsma DI, Hoentjen F, Horjus Talabur Horje CS, van de Meeberg PC, Willemsen G, Fu J, Wijmenga C, van Wijk F, Zhernakova A, Oldenburg B, Weersma RK, Dutch TWIN-IBD consortium and the Dutch Initiative on Crohn and Colitis
Background & aims: It is currently unclear whether reported changes in the gut microbiome are cause or consequence of inflammatory bowel disease (IBD). Therefore, we studied the gut microbiome of IBD-discordant and -concordant twin pairs, which offers the unique opportunity to assess individuals at increased risk of developing IBD, namely healthy cotwins from IBD-discordant twin pairs. Methods: Fecal samples were obtained from 99 twins (belonging to 51 twin pairs), 495 healthy age-, sex-, an...
Abstract
Cited 20 times since 2021 (4.6 per year)
source: EuropePMC
Circulation,
Volume 143, Issue 3, 19 3 2021, Pages 209-211
Changing the Paradigm in the Management of Valvular Heart Disease: In Addition to Left Ventricular Ejection Fraction, Focus on the Myocardium.
Fortuni F, Bax JJ, Delgado V
Abstract
Cited 14 times since 2021 (3.2 per year)
source: EuropePMC
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology,
Volume 32, Issue 4, 18 3 2021, Pages 720-726
Safety and effectiveness of omalizumab for the treatment of chronic urticaria in pediatric patients.
Dekkers C, Alizadeh Aghdam M, de Graaf M, Knulst AC, Meijer Y, van den Reek JMPA, Stadermann MB, Röckmann H
Background: Evidence on safety and effectiveness of omalizumab for treatment of chronic urticaria in pediatric patients is scarce and limited to case reports. In particular, drug survival of omalizumab has not yet been investigated, which is a key element in the evaluation of its clinical performance. The aim of this study was to investigate safety, effectiveness, and drug survival rates of omalizumab in a daily practice cohort of pediatric patients with chronic urticaria (CU). Methods: This is...
Abstract
