6883 results
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Endocrine connections,
Volume 9, Issue 1, 1 1 2020, Pages 55-62
The kidney, subclinical thyroid disease and cardiovascular outcomes in older patients.
Zijlstra LE, van Velzen DM, Simsek S, Mooijaart SP, van Buren M, Stott DJ, Ford I, Jukema JW, Trompet S
Objective: Thyroid hormones have been implicated to play a role in cardiovascular disease, along with studies linking thyroid hormone to kidney function. The aim of this study is to investigate whether kidney function modifies the association of subclinical thyroid dysfunction and the risk of cardiovascular outcomes. Methods: In total, 5804 patients were included in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). For the current analysis, 426 were excluded because of overt...
Abstract
Journal of the American College of Cardiology,
Volume 75, Issue 2, 1 1 2020, Pages 241
Reply: Alirocumab in Polyvascular Atherosclerotic Disease.
Zijlstra LE, Schwartz GG, Steg PG, Jukema JW
Abstract
Cited 155 times since 2020 (29.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 75, Issue 2, 1 1 2020, Pages 133-144
Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome.
Bittner VA, Szarek M, Aylward PE, Bhatt DL, Diaz R, Edelberg JM, Fras Z, Goodman SG, Halvorsen S, Hanotin C, Harrington RA, Jukema JW, Loizeau V, Moriarty PM, Moryusef A, Pordy R, Roe MT, Sinnaeve P, Tsimikas S, Vogel R, White HD, Zahger D, Zeiher AM, Steg PG, Schwartz GG, ODYSSEY OUTCOMES Committees and Investigators
Background: Lipoprotein(a) concentration is associated with cardiovascular events. Alirocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, lowers lipoprotein(a) and low-density lipoprotein cholesterol (LDL-C). Objectives: A pre-specified analysis of the placebo-controlled ODYSSEY Outcomes trial in patients with recent acute coronary syndrome (ACS) determined whether alirocumab-induced changes in lipoprotein(a) and LDL-C independently predicted major adverse cardiovascular events (...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 28, Issue 1, 1 1 2020, Pages 59
Correction to: Guidelines for the management of myocardial infarction/injury with non-obstructive coronary arteries (MINOCA): a position paper from the Dutch ACS working group.
Pustjens TFS, Appelman Y, Damman P, Ten Berg JM, Jukema JW, de Winter RJ, Agema WRP, van der Wielen MLJ, Arslan F, Rasoul S, van 't Hof AWJ
Correction to: Neth Heart J 2019 https://doi.org/10.1007/s12471-019-01344-6 The reference to the term acute coronary syndrome with normal or near-normal (non-obstructive) coronary arteries (ACSNNOCA) from Manolis et al. (2018) was inadvertently omitted to the original published article. Therefore, ….
Abstract
Cited 5 times since 2019 (1 per year)
source: Scopus
The American journal of cardiology,
Volume 125, Issue 6, 27 4 2019, Pages 948-955
Prognostic Influence of Feature Tracking Multidetector Row Computed Tomography-Derived Left Ventricular Global Longitudinal Strain in Patients with Aortic Stenosis Treated With Transcatheter Aortic Valve Implantation.
Gegenava T, van der Bijl P, Vollema EM, van der Kley F, de Weger A, Hautemann D, Reiber JHC, Ajmone Marsan N, Bax JJ, Delgado V
Computed tomography plays a central role in the evaluation of patients with severe aortic stenosis who underwent transcatheter aortic valve implantation (TAVI). Advances in left ventricular (LV) analysis with multidetector row computed tomography (MDCT) permit measurement of LV global longitudinal strain (GLS). The present study aimed at evaluating the association between feature tracking (FT) MDCT derived LV GLS and all-cause mortality in patients treated with TAVI. A total of 214 patients with...
Abstract
Cited 14 times since 2019 (2.7 per year)
source: EuropePMC
European journal of heart failure,
Volume 22, Issue 2, 20 3 2019, Pages 330-337
Impact of aspirin on takotsubo syndrome: a propensity score-based analysis of the InterTAK Registry.
D'Ascenzo F, Gili S, Bertaina M, Iannaccone M, Cammann VL, Di Vece D, Kato K, Saglietto A, Szawan KA, Frangieh AH, Boffini B, Annaratone M, Sarcon A, Levinson RA, Franke J, Napp LC, Jaguszewski M, Noutsias M, Münzel T, Knorr M, Heiner S, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Pieske BM, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Hasenfuß G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Franz WM, Empen K, Felix SB, Delmas C, Lairez O, El-Battrawy I, Akin I, Borggrefe M, Horowitz JD, Kozel M, Tousek P, Widimský P, Gilyarova E, Shilova A, Gilyarov M, Biondi-Zoccai G, Winchester DE, Ukena C, Neuhaus M, Bax JJ, Prasad A, Di Mario C, Böhm M, Gasparini M, Ruschitzka F, Bossone E, Citro R, Rinaldi M, De Ferrari GM, Lüscher T, Ghadri JR, Templin C
Aims: The aim of the present study was to investigate the impact of aspirin on prognosis in takotsubo syndrome (TTS). Methods and results: Patients from the International Takotsubo (InterTAK) Registry were categorized into two groups based on aspirin prescription at discharge. A comparison of clinical outcomes between groups was performed using an adjusted analysis with propensity score (PS) stratification; results from the unadjusted analysis were also reported to note the effect of the PS adju...
Abstract
Cited 27 times since 2019 (5.2 per year)
source: EuropePMC
Medical education,
Volume 54, Issue 3, 20 3 2019, Pages 205-216
Conceptualising spaced learning in health professions education: A scoping review.
Versteeg M, Hendriks RA, Thomas A, Ommering BWC, Steendijk P
Objectives: To investigate the definitions and applications of 'spaced learning' and to propose future directions for advancing its study and practice in health professions education. Method: The authors searched five online databases for articles published on spaced learning in health professions education prior to February 2018. Two researchers independently screened articles for eligibility with set inclusion criteria. They extracted and analysed key data using both quantitative and...
Abstract
Cited 4 times since 2019 (0.8 per year)
source: EuropePMC
Forensic science international,
Volume 307, 19 3 2019, Pages 110102
Chemical attribution of the home-made explosive ETN - Part I: Liquid chromatography-mass spectrometry analysis of partially nitrated erythritol impurities.
Bezemer K, McLennan L, van Duin L, Kuijpers CJ, Koeberg M, van den Elshout J, van der Heijden A, Busby T, Yevdokimov A, Schoenmakers P, Smith J, Oxley J, van Asten A
Erythritol tetranitrate (ETN) was prepared independently by two research groups from the USA and the Netherlands. The partially nitrated impurities present in ETN were studied using liquid chromatography-mass spectrometry to address the ultimate challenge in forensic explosives investigations, i.e., providing chemical and tactical information on the production and origin of the explosive material found at a crime scene. Accurate quantification of the tri-nitrated byproduct erythritol trinitrate...
Abstract
Cited 2 times since 2019 (0.4 per year)
source: EuropePMC
Clinical case reports,
Volume 8, Issue 1, 17 3 2019, Pages 215-216
Caseous calcification of the mitral annulus assessed by multimodality imaging.
Sala ML, van Dijkman PRM, Kuijpers D
Physicians may not be familiar with caseous calcification of the mitral annulus. It can therefore easily be mistaken for other conditions including tumors. In the appropriate clinical context, by using multimodality imaging, a correct diagnosis can be made, and patient concern or even unnecessary surgery can be avoided.
Abstract
Cited 3 times since 2019 (0.6 per year)
source: EuropePMC
The Canadian journal of cardiology,
Volume 36, Issue 9, 17 3 2019, Pages 1525-1533
Myocardial Deformation in the Systemic Right Ventricle: Strain Imaging Improves Prediction of the Failing Heart.
Woudstra OI, van Dissel AC, van der Bom T, de Bruin-Bon RHACM, van Melle JP, van Dijk APJ, Vliegen HW, Mulder BJM, Tanck MWT, Meijboom FJ, Bouma BJ
Background: Predicting heart failure events in patients with a systemic right ventricle (sRV) due to transposition of the great arteries (TGA) is important for timely intensification of follow-up. This study assessed the value of strain compared with currently used parameters as predictor for heart failure-free survival in patients with sRV. Methods: In participants of a multicentre trial, speckle-tracking echocardiography (STE) was performed to assess global longitudinal strain (GLS), mechanica...
Abstract
Cited 30 times since 2019 (5.7 per year)
source: EuropePMC
Journal of lipid research,
Volume 61, Issue 3, 16 3 2019, Pages 365-375
Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice.
Pouwer MG, Pieterman EJ, Worms N, Keijzer N, Jukema JW, Gromada J, Gusarova V, Princen HMG
Atherosclerosis-related CVD causes nearly 20 million deaths annually. Most patients are treated after plaques develop, so therapies must regress existing lesions. Current therapies reduce plaque volume, but targeting all apoB-containing lipoproteins with intensive combinations that include alirocumab or evinacumab, monoclonal antibodies against cholesterol-regulating proprotein convertase subtilisin/kexin type 9 and angiopoietin-like protein 3, may provide more benefit. We investigated the effec...
Abstract
Cited 49 times since 2019 (9.3 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 40, Issue 2, 12 2 2019, Pages 350-364
Shear Stress Regulation of Endothelial Glycocalyx Structure Is Determined by Glucobiosynthesis.
Wang G, Kostidis S, Tiemeier GL, Sol WMPJ, de Vries MR, Giera M, Carmeliet P, van den Berg BM, Rabelink TJ
Objective: Endothelial cells exposed to laminar shear stress express a thick glycocalyx on their surface that plays an important role in reducing vascular permeability and endothelial anti-inflammatory, antithrombotic, and antiangiogenic properties. Production and maintenance of this glycocalyx layer is dependent on cellular carbohydrate synthesis, but its regulation is still unknown. Approach and Results: Here, we show that biosynthesis of the major structural component of the endothelial glyco...
Abstract
Cited 52 times since 2019 (9.9 per year)
source: EuropePMC
JACC. Heart failure,
Volume 8, Issue 2, 11 2 2019, Pages 131-140
Left Ventricular Post-Infarct Remodeling: Implications for Systolic Function Improvement and Outcomes in the Modern Era.
van der Bijl P, Abou R, Goedemans L, Gersh BJ, Holmes DR, Ajmone Marsan N, Delgado V, Bax JJ
Objectives: This study sought to investigate the impact of post-infarct left ventricular (LV) remodeling on outcomes in the contemporary era. Background: LV remodeling after ST-segment elevation myocardial infarction (STEMI) is associated with heart failure and increased mortality. Pivotal studies have mostly been performed in the era of thrombolysis, whereas the long-term prognostic impact of LV remodeling has not been reinvestigated in the current era of primary percutaneous coronary intervent...
Abstract
Cited 1 times since 2019 (0.2 per year)
source: EuropePMC
Aging,
Volume 11, Issue 23, 11 2 2019, Pages 10791-10792
PCSK9 inhibition in high-risk patients.
Zijlstra LE, Mooijaart SP, Jukema JW
Abstract
Cited 69 times since 2019 (13.1 per year)
source: EuropePMC
Nature reviews. Cardiology,
Volume 17, Issue 5, 9 2 2019, Pages 298-312
Assessment of mitral valve regurgitation by cardiovascular magnetic resonance imaging.
Garg P, Swift AJ, Zhong L, Carlhäll CJ, Ebbers T, Westenberg J, Hope MD, Bucciarelli-Ducci C, Bax JJ, Myerson SG
Mitral regurgitation (MR) is a common valvular heart disease and is the second most frequent indication for heart valve surgery in Western countries. Echocardiography is the recommended first-line test for the assessment of valvular heart disease, but cardiovascular magnetic resonance imaging (CMR) provides complementary information, especially for assessing MR severity and to plan the timing of intervention. As new CMR techniques for the assessment of MR have arisen, standardizing CMR protocols...
Abstract
Cited 3 times since 2019 (0.6 per year)
source: EuropePMC
The pharmacogenomics journal,
Volume 20, Issue 3, 6 1 2019, Pages 482-493
Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry.
de las Fuentes L, Sung YJ, Sitlani CM, Avery CL, Bartz TM, Keyser C, Evans DS, Li X, Musani SK, Ruiter R, Smith AV, Sun F, Trompet S, Xu H, Arnett DK, Bis JC, Broeckel U, Busch EL, Chen YI, Correa A, Cummings SR, Floyd JS, Ford I, Guo X, Harris TB, Ikram MA, Lange L, Launer LJ, Reiner AP, Schwander K, Smith NL, Sotoodehnia N, Stewart JD, Stott DJ, Stürmer T, Taylor KD, Uitterlinden A, Vasan RS, Wiggins KL, Cupples LA, Gudnason V, Heckbert SR, Jukema JW, Liu Y, Psaty BM, Rao DC, Rotter JI, Stricker B, Wilson JG, Whitsel EA
Hypertension (HTN) is a significant risk factor for cardiovascular morbidity and mortality. Metabolic abnormalities, including adverse cholesterol and triglycerides (TG) profiles, are frequent comorbid findings with HTN and contribute to cardiovascular disease. Diuretics, which are used to treat HTN and heart failure, have been associated with worsening of fasting lipid concentrations. Genome-wide meta-analyses with 39,710 European-ancestry (EA) individuals and 9925 African-ancestry (AA) individ...
Abstract
Cited 10 times since 2019 (1.9 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 14, Issue 3, 5 1 2019, Pages 251-257
Coronary atherosclerosis scoring with semiquantitative CCTA risk scores for prediction of major adverse cardiac events: Propensity score-based analysis of diabetic and non-diabetic patients.
van den Hoogen IJ, van Rosendael AR, Lin FY, Lu Y, Dimitriu-Leen AC, Smit JM, Scholte AJHA, Achenbach S, Al-Mallah MH, Andreini D, Berman DS, Budoff MJ, Cademartiri F, Callister TQ, Chang HJ, Chinnaiyan K, Chow BJW, Cury RC, DeLago A, Feuchtner G, Hadamitzky M, Hausleiter J, Kaufmann PA, Kim YJ, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Raff GL, Rubinshtein R, Villines TC, Gransar H, Jones EC, Peña JM, Shaw LJ, Min JK, Bax JJ
Aims: We aimed to compare semiquantitative coronary computed tomography angiography (CCTA) risk scores - which score presence, extent, composition, stenosis and/or location of coronary artery disease (CAD) - and their prognostic value between patients with and without diabetes mellitus (DM). Risk scores derived from general chest-pain populations are often challenging to apply in DM patients, because of numerous confounders. Methods: Out of a combined cohort from the Leiden University Medical Ce...
Abstract
Cited 14 times since 2019 (2.7 per year)
source: EuropePMC
The pharmacogenomics journal,
Volume 20, Issue 3, 5 1 2019, Pages 462-470
Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study.
Smit RAJ, Trompet S, Leong A, Goodarzi MO, Postmus I, Warren H, Theusch E, Barnes MR, Arsenault BJ, Li X, Feng Q, Chasman DI, Cupples LA, Hitman GA, Krauss RM, Psaty BM, Rotter JI, Cessie SL, Stein CM, Jukema JW, GIST consortium
It remains unclear whether the increased risk of new-onset type 2 diabetes (T2D) seen in statin users is due to low LDL-C concentrations, or due to the statin-induced proportional change in LDL-C. In addition, genetic instruments have not been proposed before to examine whether liability to T2D might cause greater proportional statin-induced LDL-C lowering. Using summary-level statistics from the Genomic Investigation of Statin Therapy (GIST, nmax = 40,914) and DIAGRAM (nmax = 159,208) consortia...
Abstract
Cited 5 times since 2019 (0.9 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 20, Issue 12, 1 1 2019, Pages 1332-1336
EACVI survey on multimodality training in ESC countries.
Cameli M, Marsan NA, D'Andrea A, Dweck MR, Fontes-Carvalho R, Manka R, Michalski B, Podlesnikar T, Sitges M, Popescu BA, Edvardsen T, Fox KF, Haugaa KH
One of the missions of the European Association of Cardiovascular Imaging (EACVI) is 'to promote excellence in clinical diagnosis, research, technical development, and education in cardiovascular imaging'. The future of imaging involves multimodality so each imager should have the incentive and the possibility to improve its knowledge in other cardiovascular techniques. This article presents the results of a 20 questions survey carried out in cardiovascular imaging (CVI) centres across...
Abstract
Cited 9 times since 2019 (1.7 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 12, Issue 12, 1 1 2019, Pages 2560-2570
Core Competencies in Echocardiography for Imaging Structural Heart Disease Interventions: An Expert Consensus Statement.
Hahn RT, Mahmood F, Kodali S, Lang R, Monaghan M, Gillam LD, Swaminathan M, Bonow RO, von Bardeleben RS, Bax JJ, Grayburn P, Zoghbi WA, Sengupta PP, Chandrashekhar Y, Little SH
Abstract
