6790 results
Cited 1 times since 2024 (1.4 per year)
source: EuropePMC
International journal of cardiology. Congenital heart disease,
Volume 19, 20 3 2024, Pages 100560
Using machine learning analysis to describe patterns in tissue Doppler and speckle tracking echocardiography in patients with transposition of the great arteries after arterial switch operation.
Terol Espinosa de Los Monteros C, van der Palen RLF, Van den Eynde J, Rammeloo L, Hazekamp MG, Blom NA, Kuipers IM, Ten Harkel ADJ
Background: Advanced echocardiographic techniques such as Tissue Doppler imaging (TDI) and speckle tracking echocardiography (STE) can detect more subtle changes in ventricular performance. We aimed to study the ventricular performance in patients with transposition of the great arteries (TGA) at mid-term follow-up after the arterial switch operation (ASO) with advanced echocardiographic techniques. In addition, we sought to discover new clinical phenotypes using unsupervised machine learning. M...
Abstract
BMJ open,
Volume 14, Issue 12, 20 3 2024, Pages e086629
DIAMACC: protocol of a prospective diagnostic accuracy study of the maximal systolic acceleration to detect peripheral arterial disease in patients with diabetes-related foot ulceration in the Netherlands.
Willems S, Schepers A, Hamming J, Brouwers JJWM
Introduction: Foot ulcers are one of the most serious complications of diabetes, leading to significant risks on amputation and mortality. Peripheral arterial disease (PAD) is an important factor for the development and the outcome of diabetic foot ulcers (DFU). Although prompt and accurate detection of PAD is critical to reduce complications, its diagnosis can be challenging with currently used bedside tests (such as ankle-brachial index and toe pressure) due to medial arterial calcification. A...
Abstract
Journal of pediatric nursing,
Volume 80, 19 3 2024, Pages e170-e179
Development and validation of the social determinants of health screening scale-parent form.
Yılmaz D, Güney R
Background: The American Academy of Pediatrics recommends screening children for social determinants of health (SDOH). Purpose: This study aimed to develop a valid and reliable tool for screening SDOH in children and adolescents aged 0-18 through their parents. Design and methods: This methodological research was conducted with parents of 748 children admitted to a hospital in Turkey. An item pool was created from a literature review and interviews with 30 healthcare professionals. The scale...
Abstract
Cited 1 times since 2024 (1.4 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 14, Issue 1, 18 3 2024, Pages e036206
Prognostic Implications of Right Ventricular Dysfunction in Severe Degenerative Mitral Regurgitation.
Bohbot Y, Essayagh B, Benfari G, Bax JJ, Le Tourneau T, Topilsky Y, Antoine C, Rusinaru D, Grigioni F, Ajmone Marsan N, van Wijngaarden A, Hochstadt A, Roussel JC, Diouf M, Thapa P, Michelena HI, Enriquez-Sarano M, Tribouilloy C
Background: The prevalence and impact of right ventricular dysfunction (RVD) in degenerative mitral regurgitation (DMR) is unknown. We aimed to determine whether RVD assessed by echocardiography in routine clinical practice is independently associated with mortality in patients with DMR. Methods and results: We used data from the MIDA-Q (Mitral Regurgitation International DAtabase-Quantitative) registry, which included patients with isolated DMR due to mitral valve prolapse from January 2003 to...
Abstract
Cited 1 times since 2024 (1.4 per year)
source: EuropePMC
The Lancet. Microbe,
Volume 6, Issue 2, 18 3 2024, Pages 100942
Immune responses to SARS-CoV-2 in sub-Saharan Africa and western Europe: a retrospective, population-based, cross-sectional study.
Mbow M, Hoving D, Cisse M, Diallo I, Honkpehedji YJ, Huisman W, Pothast CR, Jongsma MLM, König MH, de Kroon AC, Linh LTK, Azimi S, Tak T, Kruize YCM, Kurniawan F, Dia YA, Zhang JLH, Prins C, Roukens AHE, de Vries JJC, Wammes LJ, Smits HH, Adegnika AA, Zlei M, Kuijpers TW, Wieske L, Dieye A, Mboup S, Kremsner PG, Eftimov F, Velavan TP, Berlin I, Heemskerk MHM, Yazdanbakhsh M, Jochems SP, BEAT-COVID consortium, COVID-19 Leiden University Medical Center study team
Background: SARS-CoV-2 has been associated with a higher proportion of asymptomatic infections and lower mortality in sub-Saharan Africa than high-income countries. However, there is currently a lack of data on cellular immune responses to SARS-CoV-2 in people living in Africa compared with people in high-income regions of the world. We aimed to assess geographical variation in peripheral and mucosal immune responses. Methods: In this retrospective, population-based, cross-sectional study, we an...
Abstract
BMC infectious diseases,
Volume 24, Issue 1, 18 3 2024, Pages 1444
The frequency of serious bacterial infection in febrile infants less than 90 days infected with SARS-CoV-2 and other respiratory viral pathogens.
Yigit H, Ulusoy E, Guneysu ST, Colak O, Gultekingil A, Guleryuz OD, Yilmaz D, Duman M, Teksam O
Background: The primary aim of this study was to compare the groups, SARS-CoV-2-positive and -negative patients, in terms of the frequency of SBI. The SARS-CoV-2-positive group was compared with the other-RVPs-positive group as a secondary evaluation in terms of serious bacterial infection (SBI). Methods: This retrospective multicenter cohort study was conducted at four university hospitals from March 2020 to December 2021. Patients under 90 days old, with a measured fever of ≥ 38 °C, who were t...
Abstract
Tijdschrift voor gerontologie en geriatrie,
Volume 55, Issue 3, 17 3 2024, Pages 2-16
[Clinical ethics support with CURA. Acceptability and feasibility among medical practitioners in geriatric and palliative medicine].
Swart LM, van Schaik MV, Garstman CCS, Sizoo EM, Metselaar S
Introduction: Moral conflicts are common within geriatric and palliative care and can lead to moral distress. Clinical ethics support helps healthcare providers in managing moral conflicts and moral distress. CURA is a low-threshold clinical ethics support instrument. The feasibility for nurses and nurse-assistants in palliative care has already been investigated. However, the acceptability and feasibility of CURA within medical practitioners is unclear. Methods: Prospective cohort study, using...
Abstract
Journal of dairy science,
Volume 108, Issue 3, 17 3 2024, Pages 2780-2794
Dutch bovine viral diarrhea virus control program: Evaluation 2018-2023.
Strous EEC, Bisschop PIH, van Schaik G, Mars MH, Waldeck HWF, Scherpenzeel CGM, de Roo B, Wever P, Santman-Berends IMGA
Since 2018, Dutch dairy farmers have been obliged to opt for 1 of 4 routes to achieve bovine viral diarrhea virus (BVDV) freedom in the national BVDV eradication program. This observational study evaluated efficacy of the total BVDV program using indicators such as the number of persistently infected (PI) cattle, the percentage of dairy herds with a BVDV-free status, and the percentage of BVDV-free dairy herds with evidence of introduction of BVDV, as well as a cost calculation per route. The Du...
Abstract
Cited 1 times since 2024 (1.4 per year)
source: EuropePMC
European journal of human genetics : EJHG,
Volume 33, Issue 4, 15 3 2024, Pages 413-420
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between SLCO1B1 and statins and CYP2C9 and sulfonylureas.
Wolthuis DFGJ, Nijenhuis M, Soree B, de Boer-Veger NJ, Buunk AM, Guchelaar HJ, Risselada A, Rongen GAPJM, van Schaik RHN, Swen JJ, Touw DJ, van Westrhenen R, Deneer VHM, Houwink EJF
Aligned with the mission of the Dutch Pharmacogenetics Working Group (DPWG) to promote the implementation of pharmacogenetics (PGx), this guideline is specifically designed to optimize pharmacotherapy of cholesterol lowering medication (statins) and glucose lowering medication (sulfonylureas). The SLCO1B1 c.521 T > C variant reduces the activity of the SLCO1B1 transporter involved in statin transport out of the blood into the liver. High blood concentrations of statins increase the risk of se...
Abstract
Multiple sclerosis and related disorders,
Volume 93, 15 3 2024, Pages 106205
Children with MOG-IgG positive bilateral optic neuritis misdiagnosed as fulminant idiopathic intracranial hypertension.
Wendel EM, Tibussek D, Barisic N, Bertolini A, Panzer A, Chang P, Geis T, Knierim E, Nikolaus M, Nosadini M, Sartori S, Schoene-Bake JC, Yilmaz D, Reindl M, Pakeerathan T, Ayzenberg I, Rostásy K
Background: Fulminant idiopathic intracranial hypertension (IIH) is characterized by headache, rapid decrease of vision and elevated CSF-opening pressure. Objective: To delineate a subgroup of MOGAD mimicking fulminant IIH. Methods: In this case series children with MOGAD with vision loss, optic disc swelling and elevated CSF opening pressure, initially diagnosed with fulminant IIH, were included. Results: 8 MOGAD patients (median age 12.5y, f:m = 7:1) with an initial diagnosis of fulminant IIH...
Abstract
Allergy,
Volume 80, Issue 4, 14 2 2024, Pages 1060-1073
Tralokinumab Treatment in Adult Atopic Dermatitis Patients: 28-Week Evaluation of Clinical Effectiveness, Safety, Serum Proteins and Total IgE Levels.
Dekkers C, Zuithoff N, Bakker D, Knol E, Wevers A, Touwslager W, Christoffers W, Prosje P, van Lynden-van Nes A, van Lümig P, Kamsteeg M, Oosting AJ, Schuttelaar MLA, Haeck I, de Graaf M, van Wijk F, de Bruin-Weller M
Introduction and objectives: Tralokinumab-a biological that specifically targets interleukin-13-is one of the newer advanced systemic treatments for patients with moderate-to-severe atopic dermatitis (AD). Although safety and efficacy have been shown in phase-III clinical trials, daily practice data are needed. Therefore, the aim of this study was to evaluate 28-week safety and effectiveness, serum proteins and total IgE levels in adult AD patients treated with tralokinumab in daily practice. Ma...
Abstract
Heart (British Cardiac Society),
Volume 111, Issue 1, 13 2 2024, Pages 35-42
Clinical and echocardiographic parameters associated with outcomes in patients with moderate secondary mitral regurgitation.
Sarrazyn C, Fortuni F, Laenens D, Chua AP, Lopez Santi MP, Myagmardorj R, Nabeta T, Meucci MC, Singh GK, Velders BJJ, Galloo X, Bax JJ, Ajmone Marsan N
Background: Significant secondary mitral regurgitation (SMR) is known to be associated with worse prognosis. However, data focusing specifically on moderate SMR and associated risk factors are lacking. In the present study, clinical and echocardiographic parameters associated with outcomes were evaluated in a large cohort of patients with moderate SMR. Methods: Patients with moderate SMR were retrospectively included and stratified by New York Heart Association (NYHA) class and specific aetiolog...
Abstract
The Pediatric infectious disease journal,
10 2 2024
Petechial and Purpuric Rashes During a Parvovirus B19 Outbreak: Are Skin Symptoms Differentiated?
Kus S, Elvan-Tuz A, Aslan-Saritas U, Yilmaz D
Human parvovirus B19 typically causes erythema infectiosum, but unusual exanthems and hemorrhagic manifestations, such as purpuric-petechial rashes, have also been reported. PVB19-associated purpuric-petechial eruption (PAPPE) should be recognized as a distinct clinical feature of primary parvovirus B19 infection and considered in the differential diagnosis of patients with febrile purpura. This report aims to highlight several scenarios of B19V-associated petechial and purpuric rashes, which ma...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 33, Issue 1, 10 2 2024, Pages 2-4
Career perspectives of early-career cardiologists in the Netherlands.
Kalkman DN, Baggen VJM, Beusekamp JC, Kleinnibbelink G, Meijers WC, Peeters FECM, van der Wall SJ, Yilmaz D, Minneboo M, Bosch L
Abstract
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 38, Issue 3, 9 2 2024, Pages 236-238
Are New Thresholds Required for the Assessment of Right Ventricular Function in Patients With and Without Tricuspid Regurgitation?
Galloo X, Ajmone Marsan N
Abstract
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists,
7 1 2024, Pages 15266028241301278
Ultrasound-Guided vs Non-Ultrasound-Guided Angio-Seal Vascular Hemosasis After Endovascular Treatment for Peripheral Artery Disease: An Observational Study.
Groenewegen FA, Charehbili A, Panfilov IA, Engels C, De Jong WJ, Burgmans M, Van der Bogt KEA, Eefting D, Van der Steenhoven TJ, Van der Linden E, Urlings T
Clinical impact: Ultrasound visualization of vascular closure devices during endovascular access closure leads to a significant decrease in overall and major post interventional access site complications. This non-invasive and often readily available imaging technique could therefore lead to an important decrease in morbidity and subsequent overall health care costs when added to the standard intervention protocol. With the increasing use of endovascular techniques to treat peripheral artery dis...
Abstract
The Lancet regional health. Europe,
Volume 49, 5 1 2024, Pages 101163
Development and validation of artificial intelligence models for early detection of postoperative infections (PERISCOPE): a multicentre study using electronic health record data.
van der Meijden SL, van Boekel AM, Schinkelshoek LJ, van Goor H, Steyerberg EW, Nelissen RGHH, Mesotten D, Geerts BF, de Boer MGJ, Arbous MS, PERISCOPE Group
Background: Postoperative infections significantly impact patient outcomes and costs, exacerbated by late diagnoses, yet early reliable predictors are scarce. Existing artificial intelligence (AI) models for postoperative infection prediction often lack external validation or perform poorly in local settings when validated. We aimed to develop locally valid models as part of the PERISCOPE AI system to enable early detection, safer discharge, and more timely treatment of patients. Methods: We dev...
Abstract
Cited 1 times since 2024 (1.3 per year)
source: EuropePMC
European journal of clinical investigation,
Volume 55, Issue 3, 5 1 2024, Pages e14368
Risk of cardiovascular disease in elderly subjects with obesity and liver fibrosis and the potential benefit of statin treatment.
Theel WB, de Jong VD, Castro Cabezas M, Grobbee DE, Jukema JW, Trompet S
Background: Liver fibrosis progression is influenced by older age and cardiometabolic risk factors such as obesity and is associated with an increased risk of cardiovascular events. While statins may protect against cardiovascular complications, their effects in elderly individuals with obesity and liver fibrosis are unclear. Method: The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) database was used to evaluate the effect of pravastatin on major adverse cardiovascular events...
Abstract
Stem cell reports,
Volume 20, Issue 1, 5 1 2024, Pages 102371
Glycogen synthase kinase-3 inhibition and insulin enhance proliferation and inhibit maturation of human iPSC-derived cardiomyocytes via TCF and FOXO signaling.
Yuan Q, Verbueken D, Dinani R, Kim R, Schoger E, Morsink CD, Simkooei SA, Kemna LJM, Hjortnaes J, Kuster DWD, Boon RA, Zelarayan LC, van der Velden J, Buikema JW
Embryonic signaling pathways exert stage-specific effects during cardiac development, yet the precise signals for proliferation or maturation remain elusive. To uncover the cues for proliferation, we performed a combinatory cell-cycle screen for insulin and glycogen synthase kinase-3 (GSK3) inhibition in spontaneously beating human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Our analysis for proliferation, and subsequential downstream sarcomere development, gene expression...
Abstract
BJU international,
Volume 135, Issue 5, 4 1 2024, Pages 766-774
The impact of positive surgical margins after cystectomy on oncological outcomes: a nationwide study.
Bosveld J, Nguyen TQ, Boormans JL, Witjes JA, van der Heijden AG, Mehra N, Kiemeney LA, Aben KKH, ProBCI Study Group, Meijer RP, Richters A
Objective: To evaluate whether surgical margin status, alongside existing postoperative risk indicators, improves the identification of bladder cancer patients who may benefit from adjuvant therapy following radical cystectomy (RC). Methods: In this nationwide cohort study, patients aged ≥18 years diagnosed with muscle-invasive bladder cancer (MIBC) without nodal or distant metastasis (cT2-4aN0/xM0) between November 2017 and December 2020 who underwent RC were selected from the Netherlands Cance...
Abstract
