6196 results
Cited 10 times since 2009 (0.6 per year)
source: EuropePMC
Atherosclerosis,
Volume 206, Issue 2, 19 3 2009, Pages 444-450
Mannose binding lectin deficiency and triglyceride-rich lipoprotein metabolism in normolipidemic subjects.
Alipour A, van Oostrom AJ, Van Wijk JP, Verseyden C, Plokker HW, Jukema JW, Rabelink AJ, Castro Cabezas M
Mannose binding lectin (MBL) is one of the three initiators of complement activation and is therefore closely linked to inflammation. MBL deficiency has been associated with the generation of atherosclerosis. Since atherosclerosis, the complement system and postprandial lipemia are linked to inflammation, we studied postprandial lipoprotein metabolism in MBL deficiency. An observational study was carried out in 107 volunteers (21% MBL deficient). Classical cardiovascular risk factors were not di...
Abstract
Cited 98 times since 2009 (6.1 per year)
source: EuropePMC
American journal of human genetics,
Volume 84, Issue 4, 12 2 2009, Pages 468-476
Haplotype-sharing analysis implicates chromosome 7q36 harboring DPP6 in familial idiopathic ventricular fibrillation.
Alders M, Koopmann TT, Christiaans I, Postema PG, Beekman L, Tanck MW, Zeppenfeld K, Loh P, Koch KT, Demolombe S, Mannens MM, Bezzina CR, Wilde AA
Idiopathic Ventricular Fibrillation (IVF) is defined as spontaneous VF without any known structural or electrical heart disease. A family history is present in up to 20% of probands with the disorder, suggesting that at least a subset of IVF is hereditary. A genome-wide haplotype-sharing analysis was performed for identification of the responsible gene in three distantly related families in which multiple individuals died suddenly or were successfully resuscitated at young age. We identified a h...
Abstract
Cited 26 times since 2009 (1.6 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 35, Issue 5, 9 2 2009, Pages 847-52; discussion 852-3
Wall motion score index predicts mortality and functional result after surgical ventricular restoration for advanced ischemic heart failure.
Klein P, Holman ER, Versteegh MI, Boersma E, Verwey HF, Bax JJ, Dion RA, Klautz RJ
Objective: Advanced ischemic heart failure can be treated with surgical ventricular restoration (SVR). While numerous risk factors for mortality and recurrent heart failure have been identified, no plain predictor for identifying SVR patients with left ventricular damage beyond recovery is yet available. We tested echocardiographic wall motion score index (WMSI) as a predictor for mortality or poor functional result. Methods: One hundred and one patients electively operated between April 2002 an...
Abstract
Cited 52 times since 2009 (3.2 per year)
source: EuropePMC
Circulation,
Volume 119, Issue 11, 9 2 2009, Pages 1467-1472
Tricuspid valve surgery in adults with a dysfunctional systemic right ventricle: repair or replace?
Scherptong RW, Vliegen HW, Winter MM, Holman ER, Mulder BJ, van der Wall EE, Hazekamp MG
Background: In patients with a right ventricle (RV) in the systemic position, tricuspid valve surgery for regurgitation beyond adolescence is a subject of debate. The aim of the present study was to evaluate the complications, survival, and benefit of tricuspid surgery in adult patients with an atrium-level correction for transposition of the great arteries or congenitally corrected transposition of the great arteries. Methods and results: All adult patients (n=16; 7 men, 9 women; age 35+/-11 ye...
Abstract
Cited 7 times since 2009 (0.4 per year)
source: EuropePMC
European journal of pediatrics,
Volume 168, Issue 12, 5 1 2009, Pages 1479-1481
Double aortic arch with double aneuploidy--rare anomaly in combined Down and Klinefelter syndrome.
Gerretsen MF, Peelen W, Rammeloo LA, Koolbergen DR, Hruda J
A 14-month-old boy with double aneuploidy and a double aortic arch suffered from frequently recurrent severe feeding and respiratory problems. Chromosomal analysis showed a 48,XXY + 21 karyotype: a double aneuploidy of Down syndrome (DS) and Klinefelter syndrome (KS). Only four cases of double aneuploidy (DS + KS) associated with congenital heart defects have been published of which none had a double aortic arch. Our case report should draw attention to the possibility of a double aortic arch in...
Abstract
Cited 18 times since 2009 (1.1 per year)
source: EuropePMC
The Journal of general virology,
Volume 90, Issue Pt 6, 4 1 2009, Pages 1408-1416
Fusion protein is the main determinant of metapneumovirus host tropism.
de Graaf M, Schrauwen EJA, Herfst S, van Amerongen G, Osterhaus ADME, Fouchier RAM
Human metapneumovirus (HMPV) and avian metapneumovirus subgroup C (AMPV-C) infect humans and birds, respectively. This study confirmed the difference in host range in turkey poults, and analysed the contribution of the individual metapneumovirus genes to host range in an in vitro cell-culture model. Mammalian Vero-118 cells supported replication of both HMPV and AMPV-C in contrast to avian quail fibroblast (QT6) cells in which only AMPV-C replicated to high titres. Inoculation of Vero-118 and QT...
Abstract
Cited 13 times since 2009 (0.8 per year)
source: EuropePMC
Echocardiography (Mount Kisco, N.Y.),
Volume 26, Issue 3, 1 1 2009, Pages 315-323
The role of speckle tracking strain imaging in cardiac pacing.
Tops LF, Delgado V, Bax JJ
In recent years, concerns have been raised about possible harmful effects of long-term right ventricular (RV) apical pacing. These detrimental effects may be related to changes in left ventricular (LV) mechanics during RV apical pacing. As a consequence, alternative RV pacing sites have been proposed, and in selected patients an upgrade from RV to biventricular pacing may be considered. Novel two-dimensional (2D) speckle tracking strain imaging allows detailed evaluation of LV mechanics, includi...
Abstract
Critical care medicine,
Volume 37, Issue 3, 1 1 2009, Pages 1130-1131
The fate and role of mesenchymal stem cells engrafted in the heart after a myocardial infarction during a second ischemic event.
Steendijk P
Abstract
Cited 8 times since 2009 (0.5 per year)
source: EuropePMC
European journal of anaesthesiology,
Volume 26, Issue 3, 1 1 2009, Pages 253-259
Impact of calcium-channel blockers on right heart function in a controlled model of chronic pulmonary hypertension.
Zierer A, Voeller RK, Melby SJ, Steendijk P, Moon MR
Background and objective: Patients with chronic pulmonary hypertension (CPH) who demonstrate pulmonary vasodilation following calcium-channel blocker (CCB) administration are defined as 'responders'. In contrast, 'nonresponders' are patients who do not show such pulmonary vasodilation with CCB therapy. The purpose of this investigation was to study the effects of CCB therapy on right heart mechanics in experimental CCB responders versus CCB nonresponders. Methods: In 12 dogs,...
Abstract
Cited 34 times since 2009 (2.1 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 2, Issue 2, 1 1 2009, Pages e12-3
Successful deployment of a transcatheter aortic valve in bicuspid aortic stenosis: role of imaging with multislice computed tomography.
Delgado V, Tops LF, Schuijf JD, van der Kley F, van de Veire NR, Schalij MJ, Bax JJ
Abstract
Cited 12 times since 2009 (0.7 per year)
source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology,
Volume 4, Issue 5, 1 1 2009, Pages 662-668
Incidence, patient characteristics and predictors of aborted myocardial infarction in patients undergoing primary PCI: prospective study comparing pre- and in-hospital abciximab pretreatment.
Hassan AK, Jukema JW, van der Laarse A, Hasan-Ali H, Wolterbeek R, van der Kley F, Spano F, Atsma DE, Schalij MJ
Aims: This study was performed to assess the incidence, patient characteristics and predictors of aborted myocardial infarction (MI) in patients with ST-segment elevation MI (STEMI) undergoing primary percutaneous coronary intervention (PPCI). Methods and results: We enrolled 179 consecutive patients with STEMI within a fixed protocol for PPCI (Leiden MISSION! project); 90 patients received abciximab bolus in the hospital (in-hospital group) and 89 patients received abciximab bolus in the ambula...
Abstract
Cited 2 times since 2009 (0.1 per year)
source: EuropePMC
The Turkish journal of pediatrics,
Volume 51, Issue 2, 1 1 2009, Pages 187-189
A rare cause of mental motor retardation: recessive congenital methemoglobinemia type II.
Yüksel D, Senbil N, Yilmaz D, Yarali N, Gürer YK
Recessive congenital methemoglobinemia (RCM) is a very rare disorder caused by NADH- cytochrome b5 reductase (cytb5r) deficiency. It has been classified into four types. Type I presents with mild cyanosis due to a significant deficiency of cytb5r in erythrocytes only. In type II, the deficiency occurs in all tissues and causes growth and mental retardation and other neurological impairments. RCM types I and II are caused by a defect in a single gene, which is located on chromosome 22 (locus DIA...
Abstract
Cited 63 times since 2009 (3.9 per year)
source: EuropePMC
Journal of the American College of Surgeons,
Volume 208, Issue 3, 1 1 2009, Pages 434-441
Improving diagnosis of acute appendicitis: results of a diagnostic pathway with standard use of ultrasonography followed by selective use of CT.
Poortman P, Oostvogel HJ, Bosma E, Lohle PN, Cuesta MA, de Lange-de Klerk ES, Hamming JF
Background: Preoperative imaging has been demonstrated to improve diagnostic accuracy in appendicitis. This prospective study assessed the accuracy of a diagnostic pathway in acute appendicitis using ultrasonography (US) and complementary contrast-enhanced multidetector CT in a general community teaching hospital. Study design: One hundred fifty-one patients with clinically suspected appendicitis followed the designed protocol: patients underwent operations after a primary performed positive US...
Abstract
Annals of vascular surgery,
Volume 23, Issue 2, 1 1 2009, Pages 288-289
Comment on "Carotid chemodectomas: long-term results of subadventitial resection with deliberate external carotid resection".
van der Bogt KE, van Baalen JM, Hamming JF
Abstract
Cited 36 times since 2009 (2.2 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 36, Issue 2, 27 4 2009, Pages 322-329
Tranexamic acid and aprotinin in low- and intermediate-risk cardiac surgery: a non-sponsored, double-blind, randomised, placebo-controlled trial.
Later AF, Maas JJ, Engbers FH, Versteegh MI, Bruggemans EF, Dion RA, Klautz RJ
Objective: Tranexamic acid has been suggested to be as effective as aprotinin in reducing blood loss and transfusion requirements after cardiac surgery. Previous studies directly comparing both antifibrinolytics focus on high-risk cardiac surgery patients only or suffer from methodological problems. We wanted to compare the effectiveness of tranexamic acid versus aprotinin in reducing postoperative blood loss and transfusion requirements in the patient group representing the majority of cardiac...
Abstract
Cited 15 times since 2009 (0.9 per year)
source: EuropePMC
The American journal of cardiology,
Volume 103, Issue 8, 25 4 2009, Pages 1045-1050
Usefulness of echocardiographic assessment of cardiac and ascending aorta calcific deposits to predict coronary artery calcium and presence and severity of obstructive coronary artery disease.
Nucifora G, Schuijf JD, van Werkhoven JM, Jukema JW, Marsan NA, Holman ER, van der Wall EE, Bax JJ
The presence of cardiac and aortic calcific deposits has been related to coronary artery disease (CAD) and cardiovascular events. The present study aimed to evaluate whether comprehensive echocardiographic assessment of cardiac and ascending aorta calcific deposits could predict coronary calcium and obstructive CAD. A total of 140 outpatients (age 61 +/- 11 years; 90 men) without a history of CAD were studied. Aortic valve sclerosis and mitral annular, papillary muscle, and ascending aorta calci...
Abstract
Cited 28 times since 2009 (1.7 per year)
source: EuropePMC
Lung cancer (Amsterdam, Netherlands),
Volume 66, Issue 2, 20 3 2009, Pages 198-204
Comparison of EUS-guided fine needle aspiration and integrated PET-CT in restaging after treatment for locally advanced non-small cell lung cancer.
Stigt JA, Oostdijk AH, Timmer PR, Shahin GM, Boers JE, Groen HJ
Background: After induction treatment restaging of mediastinal disease in patients with stage III non-small cell lung cancer (NSCLC) may lead to selection of candidates for further surgical treatment. Nodal down-staging is the best predictive characteristic for proceeding with surgery. We report our experience in restaging with endoscopic ultrasound-guided fine needle aspirations (EUS-FNA) and with repeated integrated positron emission tomography and computed tomography (PET-CT). Methods: Twenty...
Abstract
Cited 24 times since 2009 (1.5 per year)
source: EuropePMC
Diabetes care,
Volume 32, Issue 5, 19 3 2009, Pages 839-844
PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients.
Regieli JJ, Jukema JW, Doevendans PA, Zwinderman AH, van der Graaf Y, Kastelein JJ, Grobbee DE
Objective: Activation of peroxisome proliferator-activated receptor (PPAR)-gamma signaling influences metabolic profiles and the propensity toward inflammation. Small-molecule stimulation of PPARgamma is investigated for secondary prevention of cardiovascular disease. The common PPARgamma Pro12Ala variant has functional and prognostic consequences. A protective effect of the 12Ala-allele carriership on diabetes and myocardial infarction in healthy populations has been suggested. The relevance of...
Abstract
Cited 15 times since 2009 (0.9 per year)
source: EuropePMC
Neonatology,
Volume 96, Issue 2, 19 3 2009, Pages 86-92
Inverse relationship between birth weight and blood pressure in growth-retarded but not in appropriate for gestational age infants during the first week of life.
Smal JC, Uiterwaal CS, Bruinse HW, Steendijk P, van Bel F
Background: Various studies have shown an association between low birth weight and the prevalence of elevated blood pressure later in life. However, a relationship between birth weight and blood pressure in the neonatal period has not been investigated yet. Objective: To study the relationship between birth weight and blood pressure during the first week of life. Methods: Systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial blood pressure (MBP) were measured every 8 h...
Abstract
Cited 89 times since 2009 (5.5 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 2, Issue 2, 18 3 2009, Pages 135-145
Acute effects of right ventricular apical pacing on left ventricular synchrony and mechanics.
Delgado V, Tops LF, Trines SA, Zeppenfeld K, Marsan NA, Bertini M, Holman ER, Schalij MJ, Bax JJ
Background: Chronic right ventricular (RV) apical pacing has a detrimental effect on left ventricular (LV) function. However, the acute effects of RV apical pacing on LV mechanics remain unclear. The purpose of the study was to assess the acute impact of RV apical pacing on global LV function, evaluating LV contraction synchrony and LV shortening and twist, using 2D speckle-tracking strain imaging. Methods and results: A group of 25 patients with structural normal hearts referred for electrophys...
Abstract
