6128 results
Cited 28 times since 2008 (1.6 per year)
source: EuropePMC
Current medical research and opinion,
Volume 24, Issue 3, 25 4 2008, Pages 685-694
The efficacy of statin monotherapy uptitration versus switching to ezetimibe/simvastatin: results of the EASEGO study.
Roeters van Lennep HW, Liem AH, Dunselman PH, Dallinga-Thie GM, Zwinderman AH, Jukema JW
Objective: To assess the incremental low-density lipoprotein-cholesterol (LDL-C) lowering efficacy of doubling the statin dose or switching to the ezetimibe/simvastatin 10/20 mg combination tablet (EZE/SIMVA) in patients on simvastatin 20 mg or atorvastatin 10 mg not at LDL-C target < 2.5 mmol/L. Study design and methods: Patients with documented coronary heart disease (CHD) and/or type 2 diabetes (DM2) with LDL-C > or = 2.5 and < 5.0 mmol/L despite treatment with atorvastatin 10 mg or...
Abstract
Cited 10 times since 2008 (0.6 per year)
source: EuropePMC
BMC genetics,
Volume 9, 25 4 2008, Pages 9
Estimating effects of rare haplotypes on failure time using a penalized Cox proportional hazards regression model.
Souverein OW, Zwinderman AH, Jukema JW, Tanck MW
Background: This paper describes a likelihood approach to model the relation between failure time and haplotypes in studies with unrelated individuals where haplotype phase is unknown, while dealing with the problem of unstable estimates due to rare haplotypes by considering a penalized log-likelihood. Results: The Cox model presented here incorporates the uncertainty related to the unknown phase of multiple heterozygous individuals as weights. Estimation is performed with an EM algorithm. In th...
Abstract
Cited 2 times since 2008 (0.1 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 35, Issue 3, 22 4 2008, Pages 532-534
Can cardiac iodine-123 metaiodobenzylguanidine imaging contribute to risk stratification in heart failure patients?
Bax JJ, Boogers M, Henneman MM
Abstract
Cited 44 times since 2008 (2.6 per year)
source: EuropePMC
Stem cells (Dayton, Ohio),
Volume 26, Issue 4, 17 3 2008, Pages 1083-1093
Forced myocardin expression enhances the therapeutic effect of human mesenchymal stem cells after transplantation in ischemic mouse hearts.
Grauss RW, van Tuyn J, Steendijk P, Winter EM, Pijnappels DA, Hogers B, Gittenberger-De Groot AC, van der Geest R, van der Laarse A, de Vries AA, Schalij MJ, Atsma DE
Human mesenchymal stem cells (hMSCs) have only a limited differentiation potential toward cardiomyocytes. Forced expression of the cardiomyogenic transcription factor myocardin may stimulate hMSCs to acquire a cardiomyogenic phenotype, thereby improving their possible therapeutic potential. hMSCs were transduced with green fluorescent protein (GFP) and myocardin (hMSC(myoc)) or GFP and empty vector (hMSC). After coronary ligation in immune-compromised NOD/scid mice, hMSC(myoc) (n = 10), hMSC (n...
Abstract
Cited 67 times since 2008 (3.9 per year)
source: EuropePMC
European heart journal,
Volume 29, Issue 4, 17 3 2008, Pages 557-563
Clinical value, cost-effectiveness, and safety of myocardial perfusion scintigraphy: a position statement.
Marcassa C, Bax JJ, Bengel F, Hesse B, Petersen CL, Reyes E, Underwood R, European Council of Nuclear Cardiology (ECNC), European Society of Cardiology Working Group 5 (Nuclear Cardiology and Cardiac CT), European Association of Nuclear Medicine Cardiovascular Committee
Mortality rates due to coronary artery disease (CAD) have declined in recent years as result of improved prevention, diagnosis, and management. Nonetheless, CAD remains the leading cause of death worldwide with most casualties expected to occur in developing nations. Myocardial perfusion scintigraphy (MPS) provides a highly cost-effective tool for the early detection of obstructive CAD in symptomatic individuals and contributes substantially to stratification of patients according to their risk...
Abstract
Cited 30 times since 2008 (1.8 per year)
source: EuropePMC
Clinical and vaccine immunology : CVI,
Volume 15, Issue 3, 16 3 2008, Pages 522-533
Rational combination of peptides derived from different Mycobacterium leprae proteins improves sensitivity for immunodiagnosis of M. leprae infection.
Geluk A, van der Ploeg J, Teles RO, Franken KL, Prins C, Drijfhout JW, Sarno EN, Sampaio EP, Ottenhoff TH
The stable incidence of new leprosy cases suggests that transmission of infection is continuing despite the worldwide implementation of multidrug therapy programs. Highly specific tools are required to accurately diagnose asymptomatic and early stage Mycobacterium leprae infections which are the likely sources of transmission and cannot be identified by using the detection of antibodies against phenolic glycolipid I. One of the hurdles hampering T-cell-based diagnostic tests is that M. leprae an...
Abstract
Cited 15 times since 2008 (0.9 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 95, Issue 2, 15 3 2008, Pages 119-124
Effect of intramyocardial bone marrow cell injection on left ventricular dyssynchrony and global strain.
van Ramshorst J, Atsma DE, Beeres SL, Mollema SA, Ajmone Marsan N, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
Objective: To evaluate the effect of bone marrow cell injection on global strain and left ventricular (LV) dyssynchrony. Methods: In 14 patients with severe postinfarction heart failure, 93 (14) x 10(6) autologous bone marrow cells were percutaneously injected in the infarction border zone. LV ejection fraction (LVEF), LV dyssynchrony and echocardiographic global strain were assessed at baseline and 3 months in patients and in a non-randomised control group of 10 patients with a history of infar...
Abstract
Cited 16 times since 2008 (0.9 per year)
source: EuropePMC
Archives of gerontology and geriatrics,
Volume 48, Issue 1, 4 1 2008, Pages 116-120
Elderly patients undergoing major vascular surgery: risk factors and medication associated with risk reduction.
Feringa HH, Bax JJ, Karagiannis SE, Noordzij P, van Domburg R, Klein J, Poldermans D
This study assesses risk factors in elderly vascular surgery patients and to evaluate whether perioperative cardiac medication can reduce postoperative mortality rate. In a cohort study, 1693 consecutive patients > or =65 years undergoing major non-cardiac vascular surgery were preoperatively screened for cardiac risk factors and medication. During follow-up (median: 8.2 years), mortality was noted. Hospital mortality occurred in 8.1% and long-term mortality in 28.5%. In multivariate analysis...
Abstract
Cited 43 times since 2008 (2.5 per year)
source: EuropePMC
Current pharmaceutical design,
Volume 14, Issue 12, 1 1 2008, Pages 1205-1216
Bridging innate immunity and myocardial ischemia/reperfusion injury: the search for therapeutic targets.
Arslan F, de Kleijn DP, Timmers L, Doevendans PA, Pasterkamp G
Myocardial infarction necessitates new therapeutic interventions, since it still results in high morbidity and mortality worldwide. Reperfusion therapy itself results in (acceleration of) apoptosis, called myocardial ischemia/reperfusion (I/R) injury. For several decades it is known that the inflammatory response during reperfusion is the major cause of myocardial I/R injury. Therapeutic options are limited by lack of (detailed) understanding of intra- and intercellular mechanisms between inflam...
Abstract
Cited 1 times since 2008 (0.1 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 1, Issue 1, 1 1 2008, Pages 119-128
Imaging highlights from the European Society of Cardiology, American Society of Nuclear Cardiology, and Heart Failure Society of America.
Knuuti J, Poldermans D, Udelson JE, Wackers FJ, Bax JJ
Cardiac imaging has become an integrated part in the diagnostic and prognostic work-up of patients with cardiovascular disease. In this article, highlights of scientific abstracts on cardiac imaging presented at the European Society of Cardiology (ESC), the American Society of Nuclear Cardiology (ASNC), and the Heart Failure Society of America (HFSA) are summarized.
Abstract
Journal of the American College of Cardiology,
Volume 51, Issue 4, 1 1 2008, Pages 490-512
Highlights of the year in JACC 2007.
DeMaria AN, Bax JJ, Ben-Yehuda O, Clopton P, Feld GK, Ginsburg GS, Greenberg BH, Knoke JD, Lew WY, Lima JA, Maisel AS, Narayan SM, Narula J, Sahn DJ, Tsimikas S
Abstract
Cited 23 times since 2008 (1.3 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 16, Issue 3, 1 1 2008, Pages 79-87
Guidelines for heart transplantation.
de Jonge N, Kirkels JH, Klöpping C, Lahpor JR, Caliskan K, Maat AP, Brügemann J, Erasmus ME, Klautz RJ, Verwey HF, Oomen A, Peels CH, Golüke AE, Nicastia D, Koole MA, Balk AH
Based on the changes in the field of heart transplantation and the treatment and prognosis of patients with heart failure, these updated guidelines were composed by a committee under the supervision of both the Netherlands Society of Cardiology and the Netherlands Association for Cardiothoracic surgery (NVVC and NVT).THE INDICATION FOR HEART TRANSPLANTATION IS DEFINED AS: 'End-stage heart disease not remediable by more conservative measures'.CONTRAINDICATIONS ARE: irreversible pulmonar...
Abstract
Cited 17 times since 2008 (1 per year)
source: EuropePMC
The American journal of cardiology,
Volume 101, Issue 2, 1 1 2008, Pages 144-148
Comparison of multislice computed tomography to gated single-photon emission computed tomography for imaging of healed myocardial infarcts.
Henneman MM, Schuijf JD, Dibbets-Schneider P, Stokkel MP, van der Geest RJ, van der Wall EE, Bax JJ
The aim of the study was to evaluate the performance of multislice computed tomography (MSCT) for the detection and semiquantitative analysis of healed myocardial infarct in comparison to single-photon emission computed tomography (SPECT). Recently, MSCT was shown to allow detection of myocardial infarct by the presence of hypoenhanced areas. However, direct comparisons to other imaging modalities for infarct imaging were scarce. In 69 patients with healed myocardial infarct (>3 months), the...
Abstract
Cited 169 times since 2008 (9.8 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 51, Issue 1, 1 1 2008, Pages 37-45
Statins for secondary prevention in elderly patients: a hierarchical bayesian meta-analysis.
Afilalo J, Duque G, Steele R, Jukema JW, de Craen AJ, Eisenberg MJ
Objectives: This study was designed to determine whether statins reduce all-cause mortality in elderly patients with coronary heart disease. Background: Statins continue to be underutilized in elderly patients because evidence has not consistently shown that they reduce mortality. Methods: We searched 5 electronic databases, the Internet, and conference proceedings to identify relevant trials. In addition, we obtained unpublished data for the elderly patient subgroups from 4 trials and for the s...
Abstract
Cited 19 times since 2008 (1.1 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 1, Issue 1, 1 1 2008, Pages 94-106
Noncoronary applications of cardiac multidetector row computed tomography.
Tops LF, Krishnàn SC, Schuijf JD, Schalij MJ, Bax JJ
Multidetector row computed tomography (MDCT) has a high diagnostic accuracy to evaluate coronary artery stenoses. Additionally, the 4-dimensional aspect of cardiac MDCT allows a comprehensive evaluation of cardiac structure and function. Left ventricular volumes and systolic function can be accurately assessed with MDCT, and imaging of myocardial infarction is a promising application of cardiac MDCT. In addition, MDCT may provide anatomical visualization of heart valves. Also, evaluation of anat...
Abstract
Cited 6 times since 2008 (0.3 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 16, Issue 1, 1 1 2008, Pages 30-32
Epigenetic histone acetylation modifiers in vascular remodelling - new targets for therapy in cardiovascular disease.
Pons D, Jukema JW
Abstract
Cited 1 times since 2008 (0.1 per year)
source: EuropePMC
Multimedia manual of cardiothoracic surgery : MMCTS,
Volume 2008, Issue 915, 1 1 2008, Pages mmcts.2006.002329
Surgery for supravalvular aortic stenosis - the three-patch technique.
Arnáiz E, Koolbergen D, Adsuar A, Hazekamp MG
The objective of this paper is to describe the three-patch technique for repair of supravalvular aortic stenosis (SVAS). Supravalvular aortic stenosis is a rare malformation as a result of an abnormal thickening of the aortic wall. SVAS may present in two forms: a localized form (affecting only the aortic sinotubular junction) and a diffuse form, where the aortic arch and its side branches are also affected. Since 1960, multiple surgical techniques have been described with the aim of relieving t...
Abstract
Cited 3 times since 2008 (0.2 per year)
source: EuropePMC
Mayo Clinic proceedings,
Volume 83, Issue 1, 1 1 2008, Pages 10-12
Can coronary calcification define the warranty period of a normal myocardial perfusion study?
Bax JJ, Schuijf JD
Abstract
Cited 57 times since 2008 (3.3 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 15, Issue 1, 1 1 2008, Pages 127-136
Assessment of left ventricular mechanical dyssynchrony by phase analysis of ECG-gated SPECT myocardial perfusion imaging.
Chen J, Henneman MM, Trimble MA, Bax JJ, Borges-Neto S, Iskandrian AE, Nichols KJ, Garcia EV
Cardiac resynchronization therapy (CRT) has shown benefits in patients with severe heart failure. However, at least 30% of patients selected for CRT by use of traditional criteria (New York Heart Association class III or IV, depressed left ventricular [LV] ejection fraction, and prolonged QRS duration) do not respond to CRT. Recent studies with tissue Doppler imaging have shown that the presence of LV dyssynchrony is an important predictor of response to CRT. Phase analysis has been developed to...
Abstract
Cited 40 times since 2008 (2.3 per year)
source: EuropePMC
The American journal of cardiology,
Volume 101, Issue 1, 1 1 2008, Pages 122-126
Influence of renal function on the usefulness of N-terminal pro-B-type natriuretic peptide as a prognostic cardiac risk marker in patients undergoing noncardiac vascular surgery.
Goei D, Schouten O, Boersma E, Welten GM, Dunkelgrun M, Lindemans J, van Gestel YR, Hoeks SE, Bax JJ, Poldermans D
N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) is related to stress-induced myocardial ischemia and/or volume overload, both common in patients with renal dysfunction. This might compromise the prognostic usefulness of NT-pro-BNP in patients with renal impairment before vascular surgery. We assessed the prognostic value of NT-pro-BNP in the entire strata of renal function. In 356 patients (median age 69 years, 77% men), cardiac history, glomerular filtration rate (GFR, ml/min/1.73 m(2)),...
Abstract
