Below you will find a selection of our publications (now-2005)
Please use the following link for full access to our 2022 publication in Nature Biomedical Engineering by Harlaar et al (conditional immortalization of human atrial cardiomyocytes)
Please use the following link for full access to our 2022 publication in Nature Biomedical Engineering by Harlaar et al (conditional immortalization of human atrial cardiomyocytes)
43 results
Journal of internal medicine, Volume 294, Issue 3, 21 3 2023, Pages 347-357 Light transmittance in human atrial tissue and transthoracic illumination in rats support translatability of optogenetic cardioversion of atrial fibrillation. Nyns ECA, Portero V, Deng S, Jin T, Harlaar N, Bart CI, van Brakel TJ, Palmen M, Hjortnaes J, Ramkisoensing AA, Zhang GQ, Poelma RH, Ördög B, de Vries AAF, Pijnappels DA Abstract
Cardiovascular research, Volume 118, Issue 10, 1 1 2022, Pages 2293-2303 Optical ventricular cardioversion by local optogenetic targeting and LED implantation in a cardiomyopathic rat model. Nyns ECA, Jin T, Fontes MS, van den Heuvel T, Portero V, Ramsey C, Bart CI, Zeppenfeld K, Zeppenfeld K, Schalij MJ, van Brakel TJ, Ramkisoensing AA, Zhang G, Poelma RH, Ördög B, de Vries AAF, Pijnappels DA Abstract
Circulation research, Volume 131, Issue 1, 19 3 2022, Pages 24-41 Sbk2, a Newly Discovered Atrium-Enriched Regulator of Sarcomere Integrity. van Gorp PRR, Zhang J, Liu J, Tsonaka R, Mei H, Dekker SO, Bart CI, De Coster T, Post H, Heck AJR, Schalij MJ, Atsma DE, Pijnappels DA, de Vries AAF Abstract
Nature biomedical engineering, Volume 6, Issue 4, 6 1 2022, Pages 389-402 Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation. Harlaar N, Dekker SO, Zhang J, Snabel RR, Veldkamp MW, Verkerk AO, Fabres CC, Schwach V, Lerink LJS, Rivaud MR, Mulder AA, Corver WE, Goumans MJTH, Dobrev D, Klautz RJM, Schalij MJ, Veenstra GJC, Passier R, van Brakel TJ, Pijnappels DA, de Vries AAF Abstract
Frontiers in physiology, Volume 12, 23 4 2021, Pages 710020 The Effects of Repetitive Use and Pathological Remodeling on Channelrhodopsin Function in Cardiomyocytes. Ördög B, Teplenin A, De Coster T, Bart CI, Dekker SO, Zhang J, Ypey DL, de Vries AAF, Pijnappels DA Abstract
eLife, Volume 9, 8 2 2020, Pages e55921 Self-restoration of cardiac excitation rhythm by anti-arrhythmic ion channel gating. Majumder R, De Coster T, Kudryashova N, Verkerk AO, Kazbanov IV, Ördög B, Harlaar N, Wilders R, de Vries AA, Ypey DL, Panfilov AV, Pijnappels DA Abstract
Frontiers in cardiovascular medicine, Volume 7, 31 5 2020, Pages 43 Multicellular <i>In vitro</i> Models of Cardiac Arrhythmias: Focus on Atrial Fibrillation. van Gorp PRR, Trines SA, Pijnappels DA, de Vries AAF Abstract
Science translational medicine, Volume 11, Issue 481, 1 1 2019, Pages eaau6447 An automated hybrid bioelectronic system for autogenous restoration of sinus rhythm in atrial fibrillation. Nyns ECA, Poelma RH, Volkers L, Plomp JJ, Bart CI, Kip AM, van Brakel TJ, Zeppenfeld K, Schalij MJ, Zhang GQ, de Vries AAF, Pijnappels DA Abstract
Cardiovascular research, Volume 114, Issue 14, 1 1 2018, Pages 1848-1859 Generation and primary characterization of iAM-1, a versatile new line of conditionally immortalized atrial myocytes with preserved cardiomyogenic differentiation capacity. Liu J, Volkers L, Jangsangthong W, Bart CI, Engels MC, Zhou G, Schalij MJ, Ypey DL, Pijnappels DA, de Vries AAF Abstract
eLife, Volume 7, 27 4 2018, Pages e41076 Optogenetics enables real-time spatiotemporal control over spiral wave dynamics in an excitable cardiac system. Majumder R, Feola I, Teplenin AS, de Vries AA, Panfilov AV, Pijnappels DA Abstract
Circulation. Arrhythmia and electrophysiology, Volume 10, Issue 11, 1 1 2017, Pages e005591 Localized Optogenetic Targeting of Rotors in Atrial Cardiomyocyte Monolayers. Feola I, Volkers L, Majumder R, Teplenin A, Schalij MJ, Panfilov AV, de Vries AAF, Pijnappels DA Abstract
European heart journal, Volume 38, Issue 27, 1 1 2017, Pages 2132-2136 Optogenetic termination of ventricular arrhythmias in the whole heart: towards biological cardiac rhythm management. Nyns ECA, Kip A, Bart CI, Plomp JJ, Zeppenfeld K, Schalij MJ, de Vries AAF, Pijnappels DA Abstract
Cardiovascular research, Volume 113, Issue 3, 1 1 2017, Pages 354-366 Optogenetic manipulation of anatomical re-entry by light-guided generation of a reversible local conduction block. Watanabe M, Feola I, Majumder R, Jangsangthong W, Teplenin AS, Ypey DL, Schalij MJ, Zeppenfeld K, de Vries AA, Pijnappels DA Abstract
Scientific reports, Volume 6, 13 2 2016, Pages 24334 Islands of spatially discordant APD alternans underlie arrhythmogenesis by promoting electrotonic dyssynchrony in models of fibrotic rat ventricular myocardium. Majumder R, Engels MC, de Vries AA, Panfilov AV, Pijnappels DA Abstract
Circulation. Arrhythmia and electrophysiology, Volume 9, Issue 4, 1 1 2016, Pages e003439 Allosteric Modulation of Kv11.1 (hERG) Channels Protects Against Drug-Induced Ventricular Arrhythmias. Yu Z, Liu J, van Veldhoven JP, IJzerman AP, Schalij MJ, Pijnappels DA, Heitman LH, de Vries AA Abstract
Methods in molecular biology (Clifton, N.J.), Volume 1408, 1 1 2016, Pages 319-331 Optogenetic Engineering of Atrial Cardiomyocytes. Feola I, Teplenin A, de Vries AA, Pijnappels DA Abstract
Heart rhythm, Volume 13, Issue 4, 14 2 2015, Pages 860-869 QRS prolongation after premature stimulation is associated with polymorphic ventricular tachycardia in nonischemic cardiomyopathy: Results from the Leiden Nonischemic Cardiomyopathy Study. Piers SR, Askar SF, Venlet J, Androulakis AF, Kapel GF, de Riva Silva M, Jongbloed JJ, van Tintelen JP, Schalij MJ, Pijnappels DA, Zeppenfeld K Abstract
Scientific reports, Volume 5, 21 3 2015, Pages 15187 Constitutively Active Acetylcholine-Dependent Potassium Current Increases Atrial Defibrillation Threshold by Favoring Post-Shock Re-Initiation. Bingen BO, Askar SF, Neshati Z, Feola I, Panfilov AV, de Vries AA, Pijnappels DA Abstract
Cardiovascular research, Volume 107, Issue 4, 3 1 2015, Pages 601-612 Forced fusion of human ventricular scar cells with cardiomyocytes suppresses arrhythmogenicity in a co-culture model. Engels MC, Askar SF, Jangsangthong W, Bingen BO, Feola I, Liu J, Majumder R, Versteegh MI, Braun J, Klautz RJ, Ypey DL, De Vries AA, Pijnappels DA Abstract
Circulation research, Volume 115, Issue 4, 1 1 2014, Pages e6-7 Cardiac anisotropy, regeneration, and rhythm. Pijnappels DA, Schalij MJ, Atsma DE, de Vries AA Abstract