Nederlands tijdschrift voor geneeskunde, Volume 150, Issue 27, 1 1 2006, Pages 1523-1527 [Intramyocardial injection of autologous bone-marrow stem cells in a 74-year-old man with untreatable angina pectoris and demonstrated myocardial ischaemia]. Beeres SL, Bax JJ, Stokkel MP, Fibbe WE, van der Wall EE, Schalij MJ, Atsma DE
For a 74-year-old man with angina pectoris and demonstrated myocardial ischaemia, optimal medical treatment was insufficient. He was ineligible for coronary revascularization. To improve myocardial perfusion, autologous bone-marrow stem cells were injected into the ischaemic myocardium. During the months following the injection, the frequency of angina attacks decreased and myocardial perfusion and cardiac function improved.