Cited 3 times since 2009 (0.2 per year) source: EuropePMC Journal of child neurology, Volume 24, Issue 5, 23 4 2009, Pages 600-602 Paroxysmal tonic upgaze presenting as a clinical isolated syndrome. Senbil N, Yilmaz D, Yüksel D, Gürer Y
We report a 3.5-year-old boy with sudden onset of episodic upward deviation of the eyes that led to diagnosis of paroxysmal tonic upgaze. Cranial magnetic resonance imaging showed right-hand side dominant bilateral hyperintense lesions in the mesencephalon and the thalamus on T2-weighted images. These lesions suggested a demyelinating pathology. Corticosteroid treatment was started. The episodes of upward eye deviation and the lesions on magnetic resonance imaging completely resolved after 3 days and 3 months, respectively. After 2 years of follow-up, he was symptom-free. Our patient with an isolated brain stem syndrome and no mental status changes was diagnosed as having a clinical isolated syndrome.
