Cited 39 times since 2020 (7.9 per year) source: EuropePMC Frontiers in pharmacology, Volume 11, 11 2 2020, Pages 575540 Pharmacogenetics in Psychiatry: An Update on Clinical Usability. van Schaik RHN, Müller DJ, Serretti A, Ingelman-Sundberg M
Using pharmacogenetics in guiding drug therapy experiences a steady increase in uptake, although still leads to discussions as to its clinical use. Psychiatry constitutes a field where pharmacogenomic testing might help in guiding drug therapy. To address current challenges, this minireview provides an update regarding genotyping (SNP analysis/arrays/NGS), structural variant detection (star-alleles/CNVs/hybrid alleles), genotype-to-phenotype translations, cost-effectiveness, and actionability of results (FDA/CPIC/PharmGKB) regarding clinical importance of pre-emptive pharmacogenomic testing for prescription of antidepressants and antipsychotics.
