Cited 2 times since 2023 (1.1 per year) source: EuropePMC Microbiology spectrum, Volume 11, Issue 6, 16 3 2023, Pages e0309323 False aminoglycoside resistance in Enterobacterales and non-fermenters by an automated testing system: a descriptive study. Klein Klouwenberg PMC, Altorf-van der Kuil W, van Griethuysen AJ, Hendriks M, Kuijper EJ, Notermans DW, Schoffelen AF, ISIS-AR study group
Importance
Antimicrobial sensitivity data are important to guide antimicrobial therapy. In microbiological laboratories, routine sensitivity measurements are typically performed with automated testing systems such as VITEK2 and Phoenix. Using data from the Dutch national surveillance system for antimicrobial resistance over a 6-year period, we found that the measured minimum inhibitory concentrations for aminoglycosides in Enterobacterales and non-fermenters were too high for the Phoenix system. In addition, we observed a yearly increase in resistance for several species measured by Phoenix. These findings might have consequences for clinical treatment of patients with sepsis.
