Cited 11 times since 1994 (0.3 per year) source: EuropePMC Mayo Clinic proceedings, Volume 69, Issue 2, 1 1 1994, Pages 166-168 Fluoxetine abuse. Tinsley JA, Olsen MW, Laroche RR, Palmen MA

Objective

In this report, we describe the abuse of fluoxetine (an antidepressant) in two patients who had histories of substance abuse.

Material and methods

Specific details of the stimulant effects of fluoxetine, used in excessive dosages and in conjunction with other drugs, are discussed.

Results

After hospitalization, our two patients were able to discontinue use of fluoxetine and had improved mentation.

Conclusion

Although the mechanism for this phenomenon is unknown, we postulate that drug craving and behavioral factors are involved.

Mayo Clin Proc. 1994 2;69(2):166-168