9618 results
Cited 73 times since 2020 (15.5 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 14, Issue 1, 9 2 2020, Pages e008509
Sudden Cardiac Death Prediction in Arrhythmogenic Right Ventricular Cardiomyopathy: A Multinational Collaboration.
Cadrin-Tourigny J, Bosman LP, Wang W, Tadros R, Bhonsale A, Bourfiss M, Lie ØH, Saguner AM, Svensson A, Andorin A, Tichnell C, Murray B, Zeppenfeld K, van den Berg MP, Asselbergs FW, Wilde AAM, Krahn AD, Talajic M, Rivard L, Chelko S, Zimmerman SL, Kamel IR, Crosson JE, Judge DP, Yap SC, Van der Heijden JF, Tandri H, Jongbloed JDH, van Tintelen JP, Platonov PG, Duru F, Haugaa KH, Khairy P, Hauer RNW, Calkins H, Te Riele ASJM, James CA
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with ventricular arrhythmias (VA) and sudden cardiac death (SCD). A model was recently developed to predict incident sustained VA in patients with ARVC. However, since this outcome may overestimate the risk for SCD, we aimed to specifically predict life-threatening VA (LTVA) as a closer surrogate for SCD. Methods: We assembled a retrospective cohort of definite ARVC cases from 15 centers in North America and Europe....
Abstract
Cited 125 times since 2020 (26.6 per year)
source: EuropePMC
Nature communications,
Volume 11, Issue 1, 8 2 2020, Pages 6285
Cerebral small vessel disease genomics and its implications across the lifespan.
Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Akker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL, Beaudet G, Petit L, Tsuchida A, Zago L, Schilling S, Sigurdsson S, Gottesman RF, Lewis CE, Aggarwal NT, Lopez OL, Smith JA, Valdés Hernández MC, van der Grond J, Wright MJ, Knol MJ, Dörr M, Thomson RJ, Bordes C, Le Grand Q, Duperron MG, Smith AV, Knopman DS, Schreiner PJ, Evans DA, Rotter JI, Beiser AS, Maniega SM, Beekman M, Trollor J, Stott DJ, Vernooij MW, Wittfeld K, Niessen WJ, Soumaré A, Boerwinkle E, Sidney S, Turner ST, Davies G, Thalamuthu A, Völker U, van Buchem MA, Bryan RN, Dupuis J, Bastin ME, Ames D, Teumer A, Amouyel P, Kwok JB, Bülow R, Deary IJ, Schofield PR, Brodaty H, Jiang J, Tabara Y, Setoh K, Miyamoto S, Yoshida K, Nagata M, Kamatani Y, Matsuda F, Psaty BM, Bennett DA, De Jager PL, Mosley TH, Sachdev PS, Schmidt R, Warren HR, Evangelou E
White matter hyperintensities (WMH) are the most common brain-imaging feature of cerebral small vessel disease (SVD), hypertension being the main known risk factor. Here, we identify 27 genome-wide loci for WMH-volume in a cohort of 50,970 older individuals, accounting for modification/confounding by hypertension. Aggregated WMH risk variants were associated with altered white matter integrity (p = 2.5×10-7) in brain images from 1,738 young healthy adults, providing insight into the lifetime imp...
Abstract
Cited 17 times since 2020 (3.6 per year)
source: EuropePMC
Cancer treatment and research communications,
Volume 25, 8 2 2020, Pages 100266
Utilization of systemic treatment for metastatic bladder cancer in everyday practice: Results of a nation-wide population-based cohort study.
Richters A, Mehra N, Meijer RP, Boormans JL, van der Heijden AG, Smilde TJ, van der Heijden MS, Kiemeney LA, Aben KK
Background: With the introduction of new therapeutic options, the landscape of metastatic bladder cancer (mBC) management is shifting. We describe current clinical practice and outcomes of mBC patients as a benchmark for translation of developments into clinical practice in the near future. Patients and methods: Nation-wide population-based cohort study including all patients diagnosed with synchronous metastatic bladder cancer in the Netherlands in 2016-2017, identified through the Netherlands...
Abstract
ATS scholar,
Volume 2, Issue 2, 7 1 2020, Pages 168-171
Gender Representation in Medical Emergency Training Videos. Perpetuating Bias.
Ju M, Andler C, Robinson M, van Schaik SM
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
European heart journal. Case reports,
Volume 4, Issue 6, 7 1 2020, Pages 1-5
To treat or not to treat: left ventricular thrombus in a patient with cerebral amyloid angiopathy: a case report.
Hilt AD, Rasing I, Schalij MJ, Wermer MJH
Background: Cerebral amyloid angiopathy (CAA) is an important cause of cognitive impairment and spontaneous lobar intracerebral haemorrhage in older individuals. When necessary, anticoagulant treatment in these patients comes with two dilemmas; significant intracerebral bleeding risk with treatment vs. high risk of embolic stroke with no treatment. Case summary: A 66-year-old female patient presented to the emergency clinic with a ST-elevation myocardial infarction. Her past medical history reve...
Abstract
American journal of physiology. Heart and circulatory physiology,
Volume 320, Issue 1, 4 1 2020, Pages H245-H247
A shock-free approach for ambulatory cardioversion in atrial fibrillation.
De Coster T
Atrial fibrillation (AF), the most common persistent arrhythmia, is terminated most effectively by electrical cardioversion. This therapy requires in-hospital sedation to relieve the pain caused by electric shocks. Recently, our research group showed how the heart itself could be enabled to detect and terminate arrhythmias, including AF, thereby revealing the discovery of fully biological, shock-free cardioversion. Because of its biological nature, neither electric shocks nor hardware/software i...
Abstract
Cited 13 times since 2020 (2.8 per year)
source: EuropePMC
Cancer treatment and research communications,
Volume 25, 4 1 2020, Pages 100264
Survival after radical cystectomy: Progressive versus De novo muscle invasive bladder cancer.
Vlaming M, Kiemeney LALM, van der Heijden AG
Background: Despite treatment with radical cystectomy, patients with muscle invasive bladder cancer (MIBC) have a poor survival. It has been reported that survival is worse in NMIBC patients who progressed to MIBC in comparison to patients with de novo MIBC. The objective of this study was to compare survival of progressive versus de novo MIBC. Secondary objective was to explain this difference in survival by clinicopathological factors. Methods: 431 patients with MIBC who underwent radical cyst...
Abstract
Cited 6 times since 2020 (1.3 per year)
source: EuropePMC
CVIR endovascular,
Volume 3, Issue 1, 4 1 2020, Pages 91
Embolization of the false lumen using IMPEDE-FX embolization plugs as part of treatment of an infrarenal post-dissection aneurysm: a case report.
Jansen AS, van Schaik PM, Martens JM, Reijnen MMPJ
Background: This case report demonstrates the value of IMPEDE-FX plugs in an embolization procedure of a false lumen of an infrarenal post-dissection aneurysm. Case presentation: A 69-year-old patient was treated with mitral valve replacement, complicated by a Stanford type-A dissection. After 9 years he presented with an enlarging infrarenal post-dissection aneurysm. The false lumen was embolized using multiple IMPEDE-FX plugs as part of the treatment in addition to embolization of the inferior...
Abstract
Cited 7 times since 2020 (1.5 per year)
source: EuropePMC
Veterinary journal (London, England : 1997),
Volume 268, 3 1 2020, Pages 105576
Emergence of fatal Mannheimia haemolytica infections in cattle in the Netherlands.
Biesheuvel MM, van Schaik G, Meertens NM, Peperkamp NH, van Engelen E, van Garderen E
In the Dutch national surveillance system, outbreaks of fatal infections by Mannheimia haemolytica (M. haemolytica) in dairy cows and veal calves have become apparent in recent years. These observations prompted an in-depth analysis of available pathology data over the period 2004-2018 to investigate changes in the occurrence and/or expression of M. haemolytica-associated cattle disease. With multilevel logistic regression models, time trends were identified and corrected for farm, season, patho...
Abstract
Cited 5 times since 2020 (1.1 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 21, Issue 23, 3 1 2020, Pages E9244
Assessment of Microvessel Permeability in Murine Atherosclerotic Vein Grafts Using Two-Photon Intravital Microscopy.
Baganha F, Ritsma L, Quax PHA, de Vries MR
Plaque angiogenesis and plaque hemorrhage are major players in the destabilization and rupture of atherosclerotic lesions. As these are dynamic processes, imaging of plaque angiogenesis, especially the integrity or leakiness of angiogenic vessels, can be an extremely useful tool in the studies on atherosclerosis pathophysiology. Visualizing plaque microvessels in 3D would enable us to study the architecture and permeability of adventitial and intimal plaque microvessels in advanced atherosclerot...
Abstract
Cited 18 times since 2020 (3.8 per year)
source: EuropePMC
European journal of pediatrics,
Volume 180, Issue 2, 2 1 2020, Pages 617-625
Predictive factors for surgical treatment in preterm neonates with necrotizing enterocolitis: a multicenter case-control study.
El Manouni El Hassani S, Niemarkt HJ, Derikx JPM, Berkhout DJC, Ballón AE, de Graaf M, de Boode WP, Cossey V, Hulzebos CV, van Kaam AH, Kramer BW, van Lingen RA, Vijlbrief DC, van Weissenbruch MM, Benninga MA, de Boer NKH, de Meij TGJ
Necrotizing enterocolitis (NEC) is one of the most common and lethal gastrointestinal diseases in preterm infants. Early recognition of infants in need for surgical intervention might enable early intervention. In this multicenter case-control study, performed in nine neonatal intensive care units, preterm born infants (< 30 weeks of gestation) diagnosed with NEC (stage ≥ IIA) between October 2014 and August 2017 were divided into two groups: (1) medical (conservative treatment) and (2) surgi...
Abstract
Cited 7 times since 2020 (1.5 per year)
source: EuropePMC
JACC. Basic to translational science,
Volume 5, Issue 12, 2 1 2020, Pages 1228-1239
Phosphorylcholine Antibodies Preserve Cardiac Function and Reduce Infarct Size by Attenuating the Post-Ischemic Inflammatory Response.
Pluijmert NJ, de Jong RCM, de Vries MR, Pettersson K, Atsma DE, Jukema JW, Quax PHA
Phosphorylcholine monoclonal immunoglobulin G antibody attenuates the immediate post-ischemic inflammatory response by reducing the proinflammatory chemokine (C-C motif) ligand 2 chemokine and circulating Ly-6Chi monocytes. This subsequently enhances the post-ischemic repair process, resulting in limited adverse cardiac remodeling and preservation of cardiac function. Therefore, phosphorylcholine monoclonal immunoglobulin G antibody therapy may be a valid therapeutic approach against myocardial...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Chaos (Woodbury, N.Y.),
Volume 30, Issue 12, 1 1 2020, Pages 121107
Universal mechanisms for self-termination of rapid cardiac rhythm.
Biasci V, Sacconi L, Cytrynbaum EN, Pijnappels DA, De Coster T, Shrier A, Glass L, Bub G
Excitable media sustain circulating waves. In the heart, sustained circulating waves can lead to serious impairment or even death. To investigate factors affecting the stability of such waves, we have used optogenetic techniques to stimulate a region at the apex of a mouse heart at a fixed delay after the detection of excitation at the base of the heart. For long delays, rapid circulating rhythms can be sustained, whereas for shorter delays, there are paroxysmal bursts of activity that start and...
Abstract
Cited 3 times since 2020 (0.6 per year)
source: EuropePMC
Atherosclerosis. Supplements,
Volume 42, 1 1 2020, Pages e65-e71
Improving lipid management in patients with acute coronary syndrome: The ACS Lipid EuroPath tool.
Sionis A, Catapano AL, De Ferrari GM, Dudek D, Jukema JW, Landmesser U, Pirillo A, Schiele F, Zaman A, Zamorano JL
Post-acute coronary syndrome (ACS) patients are at very high risk for recurrent events and mortality, despite the availability of effective pharmacological approaches. In 2018, the ACS EuroPath Survey, performed in collaboration with 555 European cardiologists, identified a sub-optimal LDL-C management in post-ACS patients. Based on these premises, the ACS EuroPath II project led to the development of a self-assessment tool to improve lipid management in these very high risk patients, taking int...
Abstract
Cited 21 times since 2020 (4.5 per year)
source: EuropePMC
Atherosclerosis. Supplements,
Volume 42, 1 1 2020, Pages e49-e58
Lipid-lowering therapy and low-density lipoprotein cholesterol goal achievement in patients with acute coronary syndromes: The ACS patient pathway project.
Landmesser U, Pirillo A, Farnier M, Jukema JW, Laufs U, Mach F, Masana L, Pedersen TR, Schiele F, Steg G, Tubaro M, Zaman A, Zamorano P, Catapano AL
Background and aims: Post-acute coronary syndrome (ACS) patients are at very high risk for recurrent events and mortality, despite the availability of effective pharmacological approaches. Aim of this survey was to evaluate the compliance to ESC/EAS guidelines during the management of ACS patients and the effectiveness of secondary prevention in seven European countries. Methods: By means of an online questionnaire, data on 2775 ACS patients (either acute case or follow-up patients) were collect...
Abstract
Cited 36 times since 2020 (7.6 per year)
source: EuropePMC
Emerging microbes & infections,
Volume 9, Issue 1, 1 1 2020, Pages 1206-1218
Cointegration as a mechanism for the evolution of a KPC-producing multidrug resistance plasmid in <i>Proteus mirabilis</i>.
Hua X, Zhang L, Moran RA, Xu Q, Sun L, van Schaik W, Yu Y
The incidence and transmission of Klebsiella pneumoniae carbapenemase (KPC) producing plasmids have been well documented. However, the evolutionary dynamics of KPC plasmids and their fitness costs are not well characterized. Here, two carbapenemase-producing plasmids from Proteus mirabilis, pT18 and pT211 (both carrying bla KPC-2), were characterized through whole genome sequencing. pT211 is a 24.2 kbp N-type plasmid that contains bla KPC-2 and a single copy of the IS6-family insertion sequence...
Abstract
Cited 9 times since 2020 (1.9 per year)
source: EuropePMC
Pituitary,
Volume 23, Issue 6, 1 1 2020, Pages 613-621
The importance of specialized sleep investigations in children with a suprasellar tumor.
van Schaik J, Pillen S, van Litsenburg RRL, Vandenbussche NLE, de Bont JM, Schouten-van Meeteren AYN, van Santen HM
Purpose: Disruption of sleep has great impact on quality of life. In children with a suprasellar tumor and hypothalamic-pituitary dysfunction, the circadian rhythm may be disturbed causing sleep problems. However, also other factors may influence sleep. Awareness of these different etiologies and careful history taking with appropriate additional diagnostics will aid in restoring sleep quality. Methods: We present the workup of 4 cases with a suprasellar tumor and disturbances of sleep initiatio...
Abstract
Cited 11 times since 2020 (2.3 per year)
source: EuropePMC
The Journal of nutrition,
Volume 150, Issue 12, 1 1 2020, Pages 3171-3179
The Association of Vitamin D and Vitamin K Status with Subclinical Measures of Cardiovascular Health and All-Cause Mortality in Older Adults: The Hoorn Study.
Dal Canto E, Beulens JWJ, Elders P, Rutters F, Stehouwer CDA, van der Heijden AA, van Ballegooijen AJ
Background: A low vitamin D and K status has been associated with increased cardiovascular disease (CVD) risk but the evidence of their combined effect on cardiovascular health is limited. Objectives: Our study aimed to investigate the prospective association of vitamin D and K status with subclinical measures of cardiovascular health and all-cause mortality among a population of Dutch Caucasians. Methods: We performed an observational prospective study on 601 participants of the Hoorn Study (me...
Abstract
Cited 41 times since 2020 (8.7 per year)
source: EuropePMC
JAMA cardiology,
Volume 5, Issue 12, 1 1 2020, Pages 1338-1348
Stress Myocardial Perfusion Imaging vs Coronary Computed Tomographic Angiography for Diagnosis of Invasive Vessel-Specific Coronary Physiology: Predictive Modeling Results From the Computed Tomographic Evaluation of Atherosclerotic Determinants of Myocardial Ischemia (CREDENCE) Trial.
Stuijfzand WJ, van Rosendael AR, Lin FY, Chang HJ, van den Hoogen IJ, Gianni U, Choi JH, Doh JH, Her AY, Koo BK, Nam CW, Park HB, Shin SH, Cole J, Gimelli A, Khan MA, Lu B, Gao Y, Nabi F, Nakazato R, Schoepf UJ, Driessen RS, Bom MJ, Thompson R, Jang JJ, Ridner M, Rowan C, Avelar E, Généreux P, Knaapen P, de Waard GA, Pontone G, Andreini D, Al-Mallah MH, Lu Y, Berman DS, Narula J, Min JK, Bax JJ, Shaw LJ, CREDENCE Investigators
Importance: Stress imaging has been the standard for diagnosing functionally significant coronary artery disease. It is unknown whether novel, atherosclerotic plaque measures improve accuracy beyond coronary stenosis for diagnosing invasive fractional flow reserve (FFR) measurement. Objective: To compare the diagnostic accuracy of comprehensive anatomic (obstructive and nonobstructive atherosclerotic plaque) vs functional imaging measures for estimating vessel-specific FFR. Design, setting, and...
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 45, 1 1 2020, Pages 4318-4320
The difficult decision of when and in whom to perform isolated tricuspid valve surgery.
Delgado V, Ajmone Marsan N, Bax JJ
Abstract
