8953 results
Cited 27 times since 2020 (5.4 per year)
source: EuropePMC
Arthritis & rheumatology (Hoboken, N.J.),
Volume 72, Issue 11, 29 5 2020, Pages 1897-1904
Association of Anti-Topoisomerase I Antibodies of the IgM Isotype With Disease Progression in Anti-Topoisomerase I-Positive Systemic Sclerosis.
Boonstra M, Bakker JA, Grummels A, Ninaber MK, Ajmone Marsan N, Wortel CM, Huizinga TWJ, Jordan S, Hoffman-Vold AM, Distler O, Toes REM, Scherer HU, de Vries-Bouwstra JK
Objective: Anti-topoisomerase I (anti-topo I) autoantibodies in systemic sclerosis (SSc) are associated with diffuse skin involvement and interstitial lung fibrosis. Thus far, however, the relationship between anti-topo I antibody response and disease course has not yet been fully evaluated. This study was undertaken to gain insight into the association between characteristics of the anti-topo I antibody response and clinical disease course in SSc patients positive for anti-topo I antibodies. Me...
Abstract
Cited 16 times since 2020 (3.2 per year)
source: EuropePMC
Scientific reports,
Volume 10, Issue 1, 29 5 2020, Pages 15968
bFGF blockade reduces intraplaque angiogenesis and macrophage infiltration in atherosclerotic vein graft lesions in ApoE3*Leiden mice.
Parma L, Peters HAB, Sluiter TJ, Simons KH, Lazzari P, de Vries MR, Quax PHA
Intraplaque angiogenesis increases the chance of unstable atherosclerotic plaque rupture and thrombus formation leading to myocardial infarction. Basic Fibroblast Growth Factor (bFGF) plays a key role in angiogenesis and inflammation and is involved in the pathogenesis of atherosclerosis. Therefore, we aim to test K5, a small molecule bFGF-inhibitor, on remodelling of accelerated atherosclerotic vein grafts lesions in ApoE3*Leiden mice. K5-mediated bFGF-signalling blockade strongly decreased int...
Abstract
Cited 11 times since 2020 (2.2 per year)
source: EuropePMC
Disease models & mechanisms,
Volume 13, Issue 9, 28 4 2020, Pages dmm044990
Disturbed nitric oxide signalling gives rise to congenital bicuspid aortic valve and aortopathy.
Peterson JC, Wisse LJ, Wirokromo V, van Herwaarden T, Smits AM, Gittenberger-de Groot AC, Goumans MTH, VanMunsteren JC, Jongbloed MRM, DeRuiter MC
Patients with a congenital bicuspid aortic valve (BAV), a valve with two instead of three aortic leaflets, have an increased risk of developing thoracic aneurysms and aortic dissection. The mechanisms underlying BAV-associated aortopathy are poorly understood. This study examined BAV-associated aortopathy in Nos3-/- mice, a model with congenital BAV formation. A combination of histological examination and in vivo ultrasound imaging was used to investigate aortic dilation and dissections in Nos3-...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Journal of vascular surgery cases and innovative techniques,
Volume 6, Issue 4, 25 4 2020, Pages 633-636
Giant true hepatic aneurysm mimicking Mirizzi syndrome.
Corion CLS, Vriens PWHE, Alwayn IPJ, Hamming JF, van Schaik J
Giant true aneurysms of the hepatic arteries are rare. Pseudoaneurysms of the hepatic arteries are more common and are mostly caused by intra-abdominal infection, iatrogenic injury, or trauma. Hepatic or cystic pseudoaneurysms are often successfully treated by embolization owing to their saccular nature as opposed to true aneurysms. We present a case of a patient with a giant true aneurysm of the proper hepatic artery, mimicking Mirizzi syndrome. Open reconstruction was successfully preformed, a...
Abstract
Cited 70 times since 2020 (14.1 per year)
source: EuropePMC
Journal of medical Internet research,
Volume 22, Issue 9, 25 4 2020, Pages e17831
Internet and Computer-Based Cognitive Behavioral Therapy for Anxiety and Depression in Adolescents and Young Adults: Systematic Review and Meta-Analysis.
Christ C, Schouten MJ, Blankers M, van Schaik DJ, Beekman AT, Wisman MA, Stikkelbroek YA, Dekker JJ
Background: Anxiety and depressive disorders are prevalent in adolescents and young adults. However, most young people with mental health problems do not receive treatment. Computerized cognitive behavior therapy (cCBT) may provide an accessible alternative to face-to-face treatment, but the evidence base in young people is limited. Objective: The objective was to perform an up-to-date comprehensive systematic review and meta-analysis of the effectiveness of cCBT in treating anxiety and depressi...
Abstract
Cited 25 times since 2020 (5 per year)
source: EuropePMC
Cells,
Volume 9, Issue 10, 24 4 2020, Pages E2164
Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits.
Heuschkel MA, Skenteris NT, Hutcheson JD, van der Valk DD, Bremer J, Goody P, Hjortnaes J, Jansen F, Bouten CVC, van den Bogaerdt A, Matic L, Marx N, Goettsch C
Calcific aortic valve disease (CAVD) is the most prevalent valvular heart disease in the developed world, yet no pharmacological therapy exists. Here, we hypothesize that the integration of multiple omic data represents an approach towards unveiling novel molecular networks in CAVD. Databases were searched for CAVD omic studies. Differentially expressed molecules from calcified and control samples were retrieved, identifying 32 micro RNAs (miRNA), 596 mRNAs and 80 proteins. Over-representation p...
Abstract
Cited 82 times since 2020 (16.5 per year)
source: EuropePMC
Surgery,
Volume 169, Issue 2, 24 4 2020, Pages 264-274
Perioperative SARS-CoV-2 infections increase mortality, pulmonary complications, and thromboembolic events: A Dutch, multicenter, matched-cohort clinical study.
Jonker PKC, van der Plas WY, Steinkamp PJ, Poelstra R, Emous M, van der Meij W, Thunnissen F, Bierman WFW, Struys MMRF, de Reuver PR, de Vries JPM, Kruijff S, Dutch Surgical COVID-19 Research Collaborative
Background: A direct comparison of severe acute respiratory syndrome coronavirus 2 positive patients with a severe acute respiratory syndrome coronavirus 2 negative control group undergoing an operative intervention during the current pandemic is lacking, and a reliable estimate of the assumed difference in morbidity and mortality between both patient categories remains unknown. Methods: We included all consecutive patients with a confirmed pre- or postoperative severe acute respiratory syndrome...
Abstract
Cited 17 times since 2020 (3.4 per year)
source: EuropePMC
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists,
Volume 28, Issue 1, 23 4 2020, Pages 78-92
Image Fusion During Standard and Complex Endovascular Aortic Repair, to Fuse or Not to Fuse? A Meta-analysis and Additional Data From a Single-Center Retrospective Cohort.
Doelare SAN, Smorenburg SPM, van Schaik TG, Blankensteijn JD, Wisselink W, Nederhoed JH, Lely RJ, Hoksbergen AWJ, Yeung KK
Purpose: To determine if image fusion will reduce contrast volume, radiation dose, and fluoroscopy and procedure times in standard and complex (fenestrated/branched) endovascular aneurysm repair (EVAR). Materials and methods: A search of the PubMed, Embase, and Cochrane databases was performed in December 2019 to identify articles describing results of standard and complex EVAR procedures using image fusion compared with a control group. Study selection, data extraction, and assessment of the me...
Abstract
Cited 5 times since 2020 (1 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 15, Issue 2, 23 4 2020, Pages 121-128
The clinical utility of FFR<sub>CT</sub> stratified by age.
Anastasius M, Maggiore P, Huang A, Blanke P, Patel MR, Nørgaard BL, Fairbairn TA, Nieman K, Akasaka T, Berman DS, Raff GL, Hurwitz Koweek LM, Pontone G, Kawasaki T, Rønnow Sand NP, Jensen JM, Amano T, Poon M, Øvrehus KA, Sonck J, Rabbat MG, Mullen S, De Bruyne B, Rogers C, Matsuo H, Bax JJ, Leipsic J
Background: CT coronary angiography (CTA) with Fractional Flow Reserve as determined by CT (FFRCT) is a safe alternative to invasive coronary angiography. A negative FFRCT has been shown to have low cardiac event rates compared to those with a positive FFRCT. However, the clinical utility of FFRCT according to age is not known. Methods: Patients' in the ADVANCE (Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care) registry, were stratified into those ≥65 or
Abstract
Cited 32 times since 2020 (6.4 per year)
source: EuropePMC
Cancers,
Volume 12, Issue 9, 21 3 2020, Pages E2692
Prognostic and Predictive Value of Tumor-Infiltrating Immune Cells in Urothelial Cancer of the Bladder.
van Wilpe S, Gerretsen ECF, van der Heijden AG, de Vries IJM, Gerritsen WR, Mehra N
The prognosis and responsiveness to chemotherapy and checkpoint inhibitors differs substantially among patients with bladder cancer (BC). There is an unmet need for biomarkers that can accurately predict prognosis and treatment outcome. Here, we describe the available literature on the prognostic and predictive value of tumor-infiltrating immune cells in BC. Current evidence indicates that a high density of tumor-infiltrating CD8+ T cells is a favorable prognostic factor, whereas PD-L1 expressio...
Abstract
Cited 7 times since 2020 (1.4 per year)
source: EuropePMC
Communications biology,
Volume 3, Issue 1, 21 3 2020, Pages 522
Large male proboscis monkeys have larger noses but smaller canines.
Matsuda I, Stark DJ, Saldivar DAR, Tuuga A, Nathan SKSS, Goossens B, van Schaik CP, Koda H
The uniquely enlarged noses of male proboscis monkeys are prominent adornments, and a sexually selected male trait. A recent study showed significant correlations among nose, body, and testis sizes and clear associations between nose size and the number of females in a male's harem. However, to date, the analyses of other common male traits, i.e., canines, are lacking. Whereas male nose size had a positive correlation with body size, we unexpectedly found a negative correlation between body...
Abstract
Cited 72 times since 2020 (14.4 per year)
source: EuropePMC
Gynecologic oncology,
Volume 159, Issue 3, 21 3 2020, Pages 649-656
Vulvar cancer subclassification by HPV and p53 status results in three clinically distinct subtypes.
Kortekaas KE, Bastiaannet E, van Doorn HC, de Vos van Steenwijk PJ, Ewing-Graham PC, Creutzberg CL, Akdeniz K, Nooij LS, van der Burg SH, Bosse T, van Poelgeest MIE
Objective: There is great need for better risk stratification in vulvar squamous cell carcinoma (VSCC). Our aim was to define the prognostic significance of stratifying VSCC based on p16 and p53 immunohistochemistry (IHC) as surrogate markers for HPV and TP53 mutations. Methods: A large retrospective cohort of surgically treated women with primary VSCC was used. VSCC were classified into three subtypes: HPV-positive (HPVpos), HPV-negative/p53 mutant (HPVneg/p53mut), and HPV-negative/p53 wildtype...
Abstract
Cited 8 times since 2020 (1.6 per year)
source: EuropePMC
Nature communications,
Volume 11, Issue 1, 21 3 2020, Pages 4760
Straightforward preparation of supramolecular Janus nanorods by hydrogen bonding of end-functionalized polymers.
Han S, Pensec S, Yilmaz D, Lorthioir C, Jestin J, Guigner JM, Niepceron F, Rieger J, Stoffelbach F, Nicol E, Colombani O, Bouteiller L
Janus cylinders are one-dimensional colloids that have two faces with different compositions and functionalities, and are useful as building blocks for advanced functional materials. Such anisotropic objects are difficult to prepare with nanometric dimensions. Here we describe a robust and versatile strategy to form micrometer long Janus nanorods with diameters in the 10-nanometer range, by self-assembly in water of end-functionalized polymers. The Janus topology is not a result of the phase seg...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
European journal of applied physiology,
Volume 120, Issue 12, 20 3 2020, Pages 2761-2772
Two isothermal challenges yield comparable physiological and subjective responses.
Klous L, Psikuta A, Gijsbertse K, Mol D, van Schaik M, Daanen HAM, Kingma BRM
Purpose: Ventilated vests are developed to reduce thermal stress by enhancing convective and evaporative cooling from skin tissue underneath the vest. The purpose of this study is to investigate whether thermal stress is equal when a ventilated vest is worn compared to a no-vest situation with similar dry thermal resistance. Methods: Nine healthy males walked on a treadmill (7 km h-1) for 45 min in a desert climate (34 °C, 20% relative humidity) with and without ventilated vest. Gastrointestinal...
Abstract
Cited 18 times since 2020 (3.6 per year)
source: EuropePMC
The Journal of arthroplasty,
Volume 36, Issue 3, 18 3 2020, Pages 863-878
Rates and Causes of 90-day Complications and Readmissions Following Outpatient Hip and Knee Arthroplasty: A Retrospective Analysis of 525 Patients in a Single Institution.
Keulen MHF, Schotanus MGM, van Haaren EH, van Hemert WLW, Heyligers IC, Boonen B
Background: Outpatient joint arthroplasty (OJA) has gained increasing popularity and success in a well-defined population. Safety concerns, in terms of complications and readmissions, however still exist. Patients and methods: This retrospective study included 525 patients (90 primary THAs, 277 primary TKAs, and 158 primary UKAs), initially planned for OJA. All complications and readmissions were evaluated for timing and cause (surgical vs medical) within a 90-day followup. Complications and rea...
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
Infection and immunity,
Volume 88, Issue 10, 18 3 2020, Pages e00204-20
Intratracheal Inoculation with Brucella melitensis in the Pregnant Guinea Pig Is an Improved Model for Reproductive Pathogenesis and Vaccine Studies.
Hensel ME, Chaki SP, Stranahan L, Gregory AE, van Schaik EJ, Garcia-Gonzalez DG, Khalaf O, Samuel JE, Arenas-Gamboa AM
Reproductive failure is the hallmark of brucellosis in animals. An uncommon but important complication in pregnant women who become acutely infected with Brucella melitensis is spontaneous pregnancy loss or vertical transmission to the fetus. Unfortunately, the mechanism behind reproductive failure is still obscure, partially due to the lack of a proper study model. Recently, it was demonstrated that intratracheal (IT) inoculation of nonpregnant guinea pigs would replicate features of clinical d...
Abstract
Cited 6 times since 2020 (1.2 per year)
source: EuropePMC
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland,
Volume 22, Issue 12, 18 3 2020, Pages 2288-2297
Timing of nasogastric tube insertion and the risk of postoperative pneumonia: an international, prospective cohort study.
EuroSurg Collaborative
Aim: Aspiration is a common cause of pneumonia in patients with postoperative ileus. Insertion of a nasogastric tube (NGT) is often performed, but this can be distressing. The aim of this study was to determine whether the timing of NGT insertion after surgery (before versus after vomiting) was associated with reduced rates of pneumonia in patients undergoing elective colorectal surgery. Method: This was a preplanned secondary analysis of a multicentre, prospective cohort study. Patients undergo...
Abstract
Cited 6 times since 2020 (1.2 per year)
source: EuropePMC
International journal of nursing education scholarship,
Volume 17, Issue 1, 18 3 2020, Pages /j/ijnes.2020.17.issue-1/ijnes-2020-0011/ijnes-202
The effectiveness of scenario-based learning to develop patient safety behavior in first year nursing students.
Yilmaz DU, Palandoken EA, Ceylan B, Akbiyik A
The aim of this study was to examine the effect of scenario-based learning (SBL) compared to traditional demonstration method on the development of patient safety behavior in first year nursing students. During the 2016-2017 academic year, the Fundamentals of Nursing course curriculum contained the teaching of demonstration method (n=168). In the academic year 2017-2018 was performed with SBL method in the same context (n=183). Objective Structured Clinical Examination (OSCE) that assesses the s...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Clinical chemistry and laboratory medicine,
Volume 59, Issue 1, 18 3 2020, Pages e13-e17
Successfully meeting analytical expectations for the fast 0/1-h algorithm for NSTEMI by internal control procedures for cardiac troponin T.
Endlich W, Mensink WJ, den Elzen WPJ, Tops LF, Cobbaert CM
Abstract
Cited 27 times since 2020 (5.4 per year)
source: EuropePMC
Biological reviews of the Cambridge Philosophical Society,
Volume 96, Issue 1, 16 3 2020, Pages 66-88
Reproductive seasonality in primates: patterns, concepts and unsolved questions.
Heldstab SA, van Schaik CP, Müller DWH, Rensch E, Lackey LB, Zerbe P, Hatt JM, Clauss M, Matsuda I
Primates, like other mammals, exhibit an annual reproductive pattern that ranges from strictly seasonal breeding to giving birth in all months of the year, but factors mediating this variation are not fully understood. We applied both a categorical description and quantitative measures of the birth peak breadth based on daily observations in zoos to characterise reproductive seasonality in 141 primate species with an average of 941 birth events per species. Absolute day length at the beginning o...
Abstract
