8684 results
Cited 20 times since 2022 (6.1 per year)
source: EuropePMC
JAMA cardiology,
Volume 7, Issue 3, 1 1 2022, Pages 309-319
Association of Plaque Location and Vessel Geometry Determined by Coronary Computed Tomographic Angiography With Future Acute Coronary Syndrome-Causing Culprit Lesions.
Han D, Lin A, Kuronuma K, Tzolos E, Kwan AC, Klein E, Andreini D, Bax JJ, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, Hadamitzky M, Kim YJ, Leipsic JA, Maffei E, Marques H, Plank F, Pontone G, Villines TC, Al-Mallah MH, de Araújo Gonçalves P, Danad I, Gransar H, Lu Y, Lee JH, Lee SE, Baskaran L, Al'Aref SJ, Yoon YE, Van Rosendael A, Budoff MJ, Samady H, Stone PH, Virmani R, Achenbach S, Narula J, Chang HJ, Min JK, Lin FY, Shaw LJ, Slomka PJ, Dey D, Berman DS
Importance: Distinct plaque locations and vessel geometric features predispose to altered coronary flow hemodynamics. The association between these lesion-level characteristics assessed by coronary computed tomographic angiography (CCTA) and risk of future acute coronary syndrome (ACS) is unknown. Objective: To examine whether CCTA-derived adverse geometric characteristics (AGCs) of coronary lesions describing location and vessel geometry add to plaque morphology and burden for identifying culpr...
Abstract
Cited 14 times since 2022 (4.3 per year)
source: EuropePMC
Human molecular genetics,
Volume 31, Issue 7, 1 1 2022, Pages 1051-1066
C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2'O-ribose methylation.
van Ingen E, van den Homberg DAL, van der Bent ML, Mei H, Papac-Milicevic N, Kremer V, Boon RA, Quax PHA, Wojta J, Nossent AY
We have previously shown that C/D box small nucleolar RNAs (snoRNAs) transcribed from the DLK1-DIO3 locus on human chromosome 14 (14q32) are associated with cardiovascular disease. DLK1-DIO3 snoRNAs are 'orphan snoRNAs' that have no known targets. We aimed to identify RNA targets and elucidate the mechanism-of-action of human SNORD113-6 (AF357425 in mice). As AF357425-knockout cells were non-viable, we induced overexpression or inhibition of AF357425 in primary murine fibroblasts and p...
Abstract
Cited 7 times since 2022 (2.1 per year)
source: EuropePMC
European journal of anaesthesiology,
Volume 39, Issue 3, 1 1 2022, Pages 210-218
Association between benzodiazepine premedication and 30-day mortality rate: A propensity-score weighted analysis of the Peri-interventional Outcome Study in the Elderly (POSE).
Kowark A, Berger M, Rossaint R, Schmid M, Coburn M, POSE-Study group
Background: Recent guidelines suggest that benzodiazepine premedication should be avoided in elderly patients, though with limited supporting evidence. Objective: We conducted a secondary analysis of the POSE data to explore the association of premedication in patients aged 80 years or older with 30-day mortality. Design: We used propensity score methods to perform a confounder-adjusted time-to-event analysis of the association between benzodiazepine premedication and 30-day mortality of the POS...
Abstract
Cited 10 times since 2022 (3.1 per year)
source: EuropePMC
British journal of nursing (Mark Allen Publishing),
Volume 31, Issue 6, 1 1 2022, Pages 322-330
Evidence-informed practice: simplifying and applying the concept for nursing students and academics.
Kumah EA, McSherry R, Bettany-Saltikov J, van Schaik P
Background: Nurses' ability to apply evidence effectively in practice is a critical factor in delivering high-quality patient care. Evidence-based practice (EBP) is recognised as the gold standard for the delivery of safe and effective person-centred care. However, decades following its inception, nurses continue to encounter difficulties in implementing EBP and, although models for its implementation offer stepwise approaches, factors, such as the context of care and its mechanistic nature...
Abstract
Cited 28 times since 2022 (8.6 per year)
source: EuropePMC
Journal of hypertension,
Volume 40, Issue 3, 1 1 2022, Pages 606-614
A low aldosterone/renin ratio and high soluble ACE2 associate with COVID-19 severity.
Akin S, Schriek P, van Nieuwkoop C, Neuman RI, Meynaar I, van Helden EJ, Bouazzaoui HE, Baak R, Veuger M, Mairuhu RATA, van den Berg L, van Driel V, Visser LE, de Jonge E, Garrelds IM, Duynstee JFAB, van Rooden JK, Ludikhuize J, Verdonk K, Caliskan K, Jansen T, van Schaik RHN, Danser AHJ
Background: The severity of COVID-19 after SARS-CoV-2 infection is unpredictable. Angiotensin-converting enzyme-2 (ACE2) is the receptor responsible for coronavirus binding, while subsequent cell entry relies on priming by the serine protease TMPRSS2 (transmembrane protease, serine 2). Although renin-angiotensin-aldosterone-system (RAAS) blockers have been suggested to upregulate ACE2, their use in COVID-19 patients is now considered well tolerated. The aim of our study was to investigate parame...
Abstract
Cited 16 times since 2022 (4.9 per year)
source: EuropePMC
European journal of anaesthesiology,
Volume 39, Issue 3, 1 1 2022, Pages 198-209
Peri-interventional outcome study in the elderly in Europe: A 30-day prospective cohort study.
POSE-Study group
Objectives: The aim of this study was to describe the 30-day mortality rate of patients aged 80 years and older undergoing surgical and nonsurgical procedures under anaesthesia in Europe and to identify risk factors associated with mortality. Design: A prospective cohort study. Setting: European multicentre study, performed from October 2017 to December 2018. Centres committed to a 30-day recruitment period within the study period. Patients: Nine thousand four hundred and ninety-seven consecutiv...
Abstract
Cited 3 times since 2022 (0.9 per year)
source: EuropePMC
European heart journal,
Volume 43, Issue 13, 1 1 2022, Pages 1288-1295
The year in cardiovascular medicine 2021: imaging.
Bucciarelli-Ducci C, Ajmone-Marsan N, Di Carli M, Nicol E
This article reviews the most relevant literature published in 2021 on the role of cardiovascular imaging in cardiovascular medicine. Coronavirus disease 2019 (COVID-19) continued to impact the healthcare landscape, resulting in reduced access to hospital-based cardiovascular care including reduced routine diagnostic cardiovascular testing. However, imaging has also facilitated the understanding of the presence and extent of myocardial damage caused by the coronavirus infection. What has dominat...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Biomedicines,
Volume 10, Issue 3, 28 4 2022, Pages 565
Blood M2-like Monocyte Polarization Is Associated with Calcific Plaque Phenotype in Stable Coronary Artery Disease: A Sub-Study of SMARTool Clinical Trial.
Sbrana S, Cecchettini A, Bastiani L, Di Giorgi N, Mazzone A, Ceccherini E, Vozzi F, Caselli C, Neglia D, Clemente A, Scholte AJHA, Parodi O, Pelosi G, Rocchiccioli S
Background: Atherosclerosis is a chronic inflammatory disease. The balance between pro- and anti-inflammatory factors, acting on the arterial wall, promotes less or more coronary plaque macro-calcification, respectively. We investigated the association between monocyte phenotypic polarization and CTCA-assessed plaque dense-calcium volume (DCV) in patients with stable coronary artery disease (CAD). Methods: In 55 patients, individual DCV component was assessed by quantitative CTCA and normalized...
Abstract
Cited 8 times since 2022 (2.5 per year)
source: EuropePMC
The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland,
Volume 21, Issue 1, 28 4 2022, Pages 1-7
Exploring the surgical personality.
Sier VQ, Schmitz RF, Schepers A, van der Vorst JR
Surgery is a demanding field, requiring determination and emotional stability. This review explores the surgical personality, addressing international personality differences between surgical and non-surgical specialties. Across the globe, surgically-interested individuals (i.e., medical students, residents, surgeons) generally scored higher on conscientiousness, open mindedness, and extraversion, and lower on neuroticism compared to non-surgically-interested contemporaries. Extraversion was inv...
Abstract
Cited 13 times since 2022 (4 per year)
source: EuropePMC
Microbiology spectrum,
Volume 10, Issue 2, 28 4 2022, Pages e0213421
Phenotypic and Genotypic Characterization of a Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae ST17-KL38 Clinical Isolate Harboring the Carbapenemase IMP-4.
He J, Du X, Zeng X, Moran RA, van Schaik W, Zou Q, Yu Y, Zhang J, Hua X
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) is a threat to global public health. We characterized a sequence type 17 (ST17) K. pneumoniae clinical isolate that was resistant to carbapenems and belonged to serotype KL38/O2. Its complete genome is comprised of a 5.1-Mb chromosome and two conjugative plasmids. The 52,578-bp N-type plasmid pXH210-IMP contains the blaIMP-4 carbapenemase gene and the quinolone resistance gene qnrS1. The 272,742-bp FII(K)-9:FIB(K)-10 plasmid pXH2...
Abstract
The international journal of cardiovascular imaging,
Volume 38, Issue 5, 26 4 2022, Pages 927-929
Patterns of cardiac involvement characterized by strain echocardiography in amyloidosis.
Tjahjadi C, Fortuni F, Stassen J, Marsan NA, Delgado V, Bax JJ
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 30, Issue 6, 24 4 2022, Pages 338-339
Multiple culprit lesions in ST-segment elevation myocardial infarction with cardiogenic shock: a case of simultaneous thrombosis of two infarct-related arteries.
Caliskan R, Ince H, Arslan F
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
British journal of pharmacology,
Volume 179, Issue 13, 23 4 2022, Pages 3382-3402
In vivo and cellular antiarrhythmic and cardiac electrophysiological effects of desethylamiodarone in dog cardiac preparations.
Kohajda Z, Virág L, Hornyik T, Husti Z, Sztojkov-Ivanov A, Nagy N, Horváth A, Varga R, Prorok J, Szlovák J, Tóth N, Gazdag P, Topal L, Naveed M, Árpádffy-Lovas T, Pászti B, Magyar T, Koncz I, Déri S, Demeter-Haludka V, Aigner Z, Ördög B, Patfalusi M, Tálosi L, Tiszlavicz L, Földesi I, Jost N, Baczkó I, Varró A
Background and purpose: The aim of the present study was to study the antiarrhythmic effects and cellular mechanisms of desethylamiodarone (DEA), the main metabolite of amiodarone (AMIO), following acute and chronic 4-week oral treatments (25-50 mg·kg-1 ·day-1 ). Experimental approach: The antiarrhythmic effects of acute iv. (10 mg·kg-1 ) and chronic oral (4 weeks, 25 mg·kg-1 ·day-1 ) administration of DEA were assessed in carbachol and tachypacing-induced dog atrial fibrillation models. Action...
Abstract
Cited 11 times since 2022 (3.4 per year)
source: EuropePMC
JMIR cardio,
Volume 6, Issue 1, 22 4 2022, Pages e29473
A Preoperative Virtual Reality App for Patients Scheduled for Cardiac Catheterization: Pre-Post Questionnaire Study Examining Feasibility, Usability, and Acceptability.
Aardoom JJ, Hilt AD, Woudenberg T, Chavannes NH, Atsma DE
Background: Pre- and postoperative anxiety is a common phenomenon associated with negative postoperative outcomes. Symptoms of posttraumatic stress disorder, such as fear, nightmares, and sleep deprivation, are prevalent in approximately 30% to 50% of patients following discharge from intensive care units after cardiac surgery. Preliminary evidence suggests a promising role of virtual reality (VR) in preventing stress-related reactions using stress inoculation training. Such training enables cog...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
Frontiers in psychiatry,
Volume 13, 22 4 2022, Pages 774251
Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies.
Syrogiannouli L, Wildisen L, Meuwese C, Bauer DC, Cappola AR, Gussekloo J, den Elzen WPJ, Trompet S, Westendorp RGJ, Jukema JW, Ferrucci L, Ceresini G, Åsvold BO, Chaker L, Peeters RP, Imaizumi M, Ohishi W, Vaes B, Völzke H, Sgarbi JA, Walsh JP, Dullaart RPF, Bakker SJL, Iacoviello M, Rodondi N, Del Giovane C
Background: In non-randomized studies (NRSs) where a continuous outcome variable (e.g., depressive symptoms) is assessed at baseline and follow-up, it is common to observe imbalance of the baseline values between the treatment/exposure group and control group. This may bias the study and consequently a meta-analysis (MA) estimate. These estimates may differ across statistical methods used to deal with this issue. Analysis of individual participant data (IPD) allows standardization of methods acr...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
The American journal of cardiology,
Volume 170, 21 3 2022, Pages 1-9
Prognostic Relevance of Right Ventricular Remodeling after ST-Segment Elevation Myocardial Infarction in Patients Treated With Primary Percutaneous Coronary Intervention.
Chimed S, van der Bijl P, Lustosa RP, Hirasawa K, Yedidya I, Fortuni F, van der Velde E, Montero-Cabezas JM, Marsan NA, Gersh BJ, Delgado V, Bax JJ
ST-segment elevation myocardial infarction (STEMI) often leads to changes in right ventricular (RV) function and size over time. The prognostic implications of RV remodeling after STEMI, however, are unknown. RV remodeling in patients who underwent STEMI with primary percutaneous coronary intervention (PCI) was defined by RV end-systolic area (RV ESA) change at 6 months after STEMI compared with baseline. The optimal threshold of RV ESA change (≥40%) to define RV remodeling was derived from spli...
Abstract
Cited 5 times since 2022 (1.5 per year)
source: EuropePMC
Evolutionary human sciences,
Volume 4, 21 3 2022, Pages e11
Four levers of reciprocity across human societies: concepts, analysis and predictions.
Lehmann L, Powers ST, van Schaik CP
This paper surveys five human societal types - mobile foragers, horticulturalists, pre-state agriculturalists, state-based agriculturalists and liberal democracies - from the perspective of three core social problems faced by interacting individuals: coordination problems, social dilemmas and contest problems. We characterise the occurrence of these problems in the different societal types and enquire into the main force keeping societies together given the prevalence of these. To address this,...
Abstract
Cited 4 times since 2022 (1.2 per year)
source: EuropePMC
International journal of cardiology,
Volume 355, 18 3 2022, Pages 65-71
Prognostic implications of staging cardiac remodeling in patients undergoing cardiac resynchronization therapy.
Stassen J, Khidir M, Galloo X, Hirasawa K, Knuuti J, Marsan NA, Delgado V, van der Bijl P, Bax JJ
Background: Cardiac resynchronization therapy (CRT) candidates often present with significant mitral and tricuspid regurgitation, pulmonary hypertension and right ventricular dysfunction when referred for device implantation. This study investigated the prognostic value of a novel cardiac staging system, based on the extent of cardiac remodeling prior to implantation. Methods: Data were collected from an ongoing registry of CRT recipients. Patients were divided into 4 groups according to the ext...
Abstract
Cited 7 times since 2022 (2.1 per year)
source: EuropePMC
Heart rhythm,
Volume 19, Issue 6, 18 3 2022, Pages 927-936
Impact of baseline left ventricular volume on left ventricular reverse remodeling after cardiac resynchronization therapy.
Galloo X, Stassen J, Hirasawa K, Chimed S, Cosyns B, Ajmone Marsan N, Delgado V, van der Bijl P, Bax JJ
Background: Left ventricular (LV) dilatation may limit LV reverse remodeling after cardiac resynchronization therapy (CRT). Objective: The purpose of this study was to evaluate the impact of baseline LV volumes on LV reverse remodeling after CRT and whether this is associated with improved survival. Methods: Patients were stratified into quintiles according to baseline LV end-diastolic volume indexed for body surface area (LVEDVi). LV reverse remodeling was defined as ≥15% reduction in LV end-sy...
Abstract
European heart journal. Case reports,
Volume 6, Issue 3, 17 3 2022, Pages ytac087
Successful hybrid cardiac resynchronization therapy in a patient with failing systemic right ventricle and significant tricuspid regurgitation in transposition of the great arteries after atrial switch procedure according to Mustard.
Nederend M, Zeppenfeld K, Jongbloed MRM, Egorova AD
Background: Patients with a systemic right ventricle (sRV) in the context of transposition of the great arteries (TGA) late after atrial switch are prone to heart failure. Complications like tricuspid valve regurgitation (TR) can further aggravate sRV dysfunction. Tricuspid valve regurgitation is usually secondary to annular dilatation and restriction. Criteria for cardiac resynchronization therapy (CRT) in this patient group are not well defined and should be considered on a case-by-case basis....
Abstract
