Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6143 results
Cited 52 times since 2019 (9.9 per year) source: EuropePMC
JACC. Heart failure, Volume 8, Issue 2, 11 2 2019, Pages 131-140 Left Ventricular Post-Infarct Remodeling: Implications for Systolic Function Improvement and Outcomes in the Modern Era. van der Bijl P, Abou R, Goedemans L, Gersh BJ, Holmes DR, Ajmone Marsan N, Delgado V, Bax JJ
Objectives: This study sought to investigate the impact of post-infarct left ventricular (LV) remodeling on outcomes in the contemporary era. Background: LV remodeling after ST-segment elevation myocardial infarction (STEMI) is associated with heart failure and increased mortality. Pivotal studies have mostly been performed in the era of thrombolysis, whereas the long-term prognostic impact of LV remodeling has not been reinvestigated in the current era of primary percutaneous coronary intervent... Abstract
Cited 1 times since 2019 (0.2 per year) source: EuropePMC
Aging, Volume 11, Issue 23, 11 2 2019, Pages 10791-10792 PCSK9 inhibition in high-risk patients. Zijlstra LE, Mooijaart SP, Jukema JW
Cited 69 times since 2019 (13.1 per year) source: EuropePMC
Nature reviews. Cardiology, Volume 17, Issue 5, 9 2 2019, Pages 298-312 Assessment of mitral valve regurgitation by cardiovascular magnetic resonance imaging. Garg P, Swift AJ, Zhong L, Carlhäll CJ, Ebbers T, Westenberg J, Hope MD, Bucciarelli-Ducci C, Bax JJ, Myerson SG
Mitral regurgitation (MR) is a common valvular heart disease and is the second most frequent indication for heart valve surgery in Western countries. Echocardiography is the recommended first-line test for the assessment of valvular heart disease, but cardiovascular magnetic resonance imaging (CMR) provides complementary information, especially for assessing MR severity and to plan the timing of intervention. As new CMR techniques for the assessment of MR have arisen, standardizing CMR protocols... Abstract
Cited 3 times since 2019 (0.6 per year) source: EuropePMC
The pharmacogenomics journal, Volume 20, Issue 3, 6 1 2019, Pages 482-493 Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. de las Fuentes L, Sung YJ, Sitlani CM, Avery CL, Bartz TM, Keyser C, Evans DS, Li X, Musani SK, Ruiter R, Smith AV, Sun F, Trompet S, Xu H, Arnett DK, Bis JC, Broeckel U, Busch EL, Chen YI, Correa A, Cummings SR, Floyd JS, Ford I, Guo X, Harris TB, Ikram MA, Lange L, Launer LJ, Reiner AP, Schwander K, Smith NL, Sotoodehnia N, Stewart JD, Stott DJ, Stürmer T, Taylor KD, Uitterlinden A, Vasan RS, Wiggins KL, Cupples LA, Gudnason V, Heckbert SR, Jukema JW, Liu Y, Psaty BM, Rao DC, Rotter JI, Stricker B, Wilson JG, Whitsel EA
Hypertension (HTN) is a significant risk factor for cardiovascular morbidity and mortality. Metabolic abnormalities, including adverse cholesterol and triglycerides (TG) profiles, are frequent comorbid findings with HTN and contribute to cardiovascular disease. Diuretics, which are used to treat HTN and heart failure, have been associated with worsening of fasting lipid concentrations. Genome-wide meta-analyses with 39,710 European-ancestry (EA) individuals and 9925 African-ancestry (AA) individ... Abstract
Cited 10 times since 2019 (1.9 per year) source: EuropePMC
Journal of cardiovascular computed tomography, Volume 14, Issue 3, 5 1 2019, Pages 251-257 Coronary atherosclerosis scoring with semiquantitative CCTA risk scores for prediction of major adverse cardiac events: Propensity score-based analysis of diabetic and non-diabetic patients. van den Hoogen IJ, van Rosendael AR, Lin FY, Lu Y, Dimitriu-Leen AC, Smit JM, Scholte AJHA, Achenbach S, Al-Mallah MH, Andreini D, Berman DS, Budoff MJ, Cademartiri F, Callister TQ, Chang HJ, Chinnaiyan K, Chow BJW, Cury RC, DeLago A, Feuchtner G, Hadamitzky M, Hausleiter J, Kaufmann PA, Kim YJ, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Raff GL, Rubinshtein R, Villines TC, Gransar H, Jones EC, Peña JM, Shaw LJ, Min JK, Bax JJ
Aims: We aimed to compare semiquantitative coronary computed tomography angiography (CCTA) risk scores - which score presence, extent, composition, stenosis and/or location of coronary artery disease (CAD) - and their prognostic value between patients with and without diabetes mellitus (DM). Risk scores derived from general chest-pain populations are often challenging to apply in DM patients, because of numerous confounders. Methods: Out of a combined cohort from the Leiden University Medical Ce... Abstract
Cited 14 times since 2019 (2.6 per year) source: EuropePMC
The pharmacogenomics journal, Volume 20, Issue 3, 5 1 2019, Pages 462-470 Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study. Smit RAJ, Trompet S, Leong A, Goodarzi MO, Postmus I, Warren H, Theusch E, Barnes MR, Arsenault BJ, Li X, Feng Q, Chasman DI, Cupples LA, Hitman GA, Krauss RM, Psaty BM, Rotter JI, Cessie SL, Stein CM, Jukema JW, GIST consortium
It remains unclear whether the increased risk of new-onset type 2 diabetes (T2D) seen in statin users is due to low LDL-C concentrations, or due to the statin-induced proportional change in LDL-C. In addition, genetic instruments have not been proposed before to examine whether liability to T2D might cause greater proportional statin-induced LDL-C lowering. Using summary-level statistics from the Genomic Investigation of Statin Therapy (GIST, nmax = 40,914) and DIAGRAM (nmax = 159,208) consortia... Abstract
Cited 5 times since 2019 (0.9 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 20, Issue 12, 1 1 2019, Pages 1332-1336 EACVI survey on multimodality training in ESC countries. Cameli M, Marsan NA, D'Andrea A, Dweck MR, Fontes-Carvalho R, Manka R, Michalski B, Podlesnikar T, Sitges M, Popescu BA, Edvardsen T, Fox KF, Haugaa KH
One of the missions of the European Association of Cardiovascular Imaging (EACVI) is 'to promote excellence in clinical diagnosis, research, technical development, and education in cardiovascular imaging'. The future of imaging involves multimodality so each imager should have the incentive and the possibility to improve its knowledge in other cardiovascular techniques. This article presents the results of a 20 questions survey carried out in cardiovascular imaging (CVI) centres across... Abstract
Cited 9 times since 2019 (1.7 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 12, Issue 12, 1 1 2019, Pages 2560-2570 Core Competencies in Echocardiography for Imaging Structural Heart Disease Interventions: An Expert Consensus Statement. Hahn RT, Mahmood F, Kodali S, Lang R, Monaghan M, Gillam LD, Swaminathan M, Bonow RO, von Bardeleben RS, Bax JJ, Grayburn P, Zoghbi WA, Sengupta PP, Chandrashekhar Y, Little SH
Journal of the American College of Cardiology, Volume 74, Issue 22, 1 1 2019, Pages 2826 Reply: Staging Cardiac Damage in Aortic Stenosis. Delgado V, Vollema EM, Tastet L, Pibarot P, Bax JJ
Cited 7 times since 2019 (1.3 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 27, Issue 12, 1 1 2019, Pages 590-593 Ventricular assist device implantation in patients with a failing systemic right ventricle: a call to expand current practice. Zandstra TE, Palmen M, Hazekamp MG, Meyns B, Beeres SLMA, Holman ER, Kiès P, Jongbloed MRM, Vliegen HW, Egorova AD, Schalij MJ, Tops LF
Ventricular assist device (VAD) implantation is an established treatment modality for patients with end-stage heart failure, and improves symptoms and survival. In the Netherlands, it is not yet routinely considered in patients with congenital heart disease and failing systemic right ventricle (SRV). Recently, a VAD was implanted in 2 SRV patients, one who underwent a Mustard procedure during infancy for transposition of the great arteries (male, 47 years old) and one with a congenitally correct... Abstract
Cited 8 times since 2019 (1.5 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 12, Issue 12, 1 1 2019, Pages 2555-2559 Core Competencies in Cardiac CT for Imaging Structural Heart Disease Interventions: An Expert Consensus Statement. Leipsic J, Nørgaard BL, Khalique O, Cavalcante JL, Wang DD, Jilaihawi H, Delgado V, Bax JJ, Blanke P
Cited 18 times since 2019 (3.4 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 12, Issue 1, 1 1 2019, Pages e008122 Interobserver Variability in Applying American Society of Echocardiography/European Association of Cardiovascular Imaging 2016 Guidelines for Estimation of Left Ventricular Filling Pressure. Nagueh SF, Abraham TP, Aurigemma GP, Bax JJ, Beladan C, Browning A, Chamsi-Pasha MA, Delgado V, Derumeaux G, Dolci G, Donal E, Edvardsen T, El Tallawi KC, Ernande L, Esposito R, Flachskampf FA, Galderisi M, Gentry J, Goldstein SA, Harb SC, Hubert A, Hung J, Klein AL, Lancellotti P, Mahmood RZ, Marino P, Popescu BA, Previato M, Sanghai SR, Smiseth OA, Xu J, for Diastolic Function Assessment Collaborators
Background: Assessment of left ventricular (LV) filling pressure is among the important components of a comprehensive echocardiographic report. Previous studies noted wide limits of agreement using 2009 American Society of Echocardiography/European Association of Echocardiography guidelines, but reproducibility of 2016 guidelines update in estimating LV filling pressure is unknown. Methods: Echocardiographic and hemodynamic data were obtained from 50 patients undergoing cardiac catheterization f... Abstract
JACC. Cardiovascular interventions, Volume 12, Issue 24, 1 1 2019, Pages 2473-2475 Mitral Annular Dilation Relative to the Length of the Leaflets and Outcome of MitraClip Implantation. Delgado V, Ajmone Marsan N, Bax JJ
Cited 33 times since 2019 (6.2 per year) source: EuropePMC
European heart journal, Volume 40, Issue 48, 1 1 2019, Pages 3901-3909 The relation between systemic inflammation and incident cancer in patients with stable cardiovascular disease: a cohort study. Van't Klooster CC, Ridker PM, Hjortnaes J, van der Graaf Y, Asselbergs FW, Westerink J, Aerts JGJV, Visseren FLJ
Aims: Low-grade inflammation, measured by elevated plasma concentrations of high-sensitive C-reactive protein (CRP), is a risk factor for cardiovascular disease (CVD). There is evidence that low-grade inflammation is also related to a higher risk of cancer. The present prospective cohort study evaluates the relation between low-grade systemic inflammation and risk of cancer in patients with stable CVD. Methods and results: In total, 7178 patients with stable CVD and plasma CRP levels ≤10 mg/L we... Abstract
Cited 22 times since 2019 (4.1 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 20, Issue 12, 1 1 2019, Pages 1388-1394 Prognostic implications of global, left ventricular myocardial work efficiency before cardiac resynchronization therapy. van der Bijl P, Vo NM, Kostyukevich MV, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ
Aims: Cardiac resynchronization therapy (CRT) restores mechanical efficiency to the failing left ventricular (LV) by resynchronization of contraction. Global, LV myocardial work efficiency (GLVMWE) can be quantified non-invasively with echocardiography. The prognostic implication of GLVMWE remains unexplored, and we therefore related GLVMWE before CRT to long-term prognosis. Methods and results: Data were analysed from an ongoing registry of patients with Class I indications for CRT. GLVMWE was... Abstract
Cited 7 times since 2019 (1.3 per year) source: Scopus
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 56, Issue 6, 1 1 2019, Pages 1117-1123 Reinterventions after freestyle stentless aortic valve replacement: an assessment of procedural risks. Schneider AW, Hazekamp MG, Versteegh MIM, de Weger A, Holman ER, Klautz RJM, Bruggemans EF, Braun J
Objectives: Repeat aortic valve interventions after previous stentless aortic valve replacement (AVR) are considered technically challenging with an increased perioperative risk, especially after full-root replacement. We analysed our experience with reinterventions after stentless AVR. Methods: A total of 75 patients with previous AVR using a Freestyle stentless bioprosthesis (31 subcoronary, 15 root-inclusion and 29 full-root replacement) underwent reintervention in our centre from 1993 until... Abstract
Cited 8 times since 2019 (1.5 per year) source: Scopus
Journal of cardiovascular computed tomography, Volume 14, Issue 3, 1 1 2019, Pages 240-245 Feature tracking computed tomography-derived left ventricular global longitudinal strain in patients with aortic stenosis: a comparative analysis with echocardiographic measurements. Gegenava T, van der Bijl P, Hirasawa K, Vollema EM, van Rosendael A, van der Kley F, de Weger A, Hautemann DJ, Reiber JHC, Ajmone Marsan N, Bax JJ, Delgado V
Background: Left ventricular (LV) systolic function is a prognostic factor in patients with severe aortic stenosis (AS). Multi-detector row computed tomography (MDCT) data are key in the evaluation of patients undergoing transcatheter aortic valve implantation (TAVI) and when acquired retrospectively, LV systolic function can be assessed. Novel software permits assessment of LV global longitudinal strain (GLS) from MDCT data. Objectives: The present study investigated the feasibility of feature... Abstract
European journal of hybrid imaging, Volume 3, Issue 1, 28 4 2019, Pages 19 Correction to: Characterization of the left ventricular arrhythmogenic substrate with multimodality imaging: role of innervation imaging and left ventricular global longitudinal strain. El Mahdiui M, Smit JM, van Rosendael AR, Delgado V, Marsan NA, Jukema JW, Scholte AJHA, Bax JJ
Cited 26 times since 2019 (4.9 per year) source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology, Volume 40, Issue 1, 26 4 2019, Pages 279-287 Intraventricular Thrombus Formation and Embolism in Takotsubo Syndrome: Insights From the International Takotsubo Registry. Ding KJ, Cammann VL, Szawan KA, Stähli BE, Wischnewsky M, Di Vece D, Citro R, Jaguszewski M, Seifert B, Sarcon A, Knorr M, Heiner S, Gili S, D'Ascenzo F, Neuhaus M, Napp LC, Franke J, Noutsias M, Burgdorf C, Koenig W, Kherad B, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Pott A, Meyer P, Arroja JD, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Paolini C, Bilato C, Carrilho-Ferreira P, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Dichtl W, Chan C, Bridgman P, Delmas C, Lairez O, El-Battrawy I, Akin I, Gilyarova E, Shilova A, Gilyarov M, Kozel M, Tousek P, Widimský P, Winchester DE, Galuszka J, Ukena C, Horowitz JD, Di Mario C, Prasad A, Rihal CS, Pinto FJ, Crea F, Borggrefe M, Braun-Dullaeus RC, Rottbauer W, Bauersachs J, Katus HA, Hasenfuß G, Tschöpe C, Pieske BM, Thiele H, Schunkert H, Böhm M, Felix SB, Münzel T, Bax JJ, Lüscher TF, Ruschitzka F, Ghadri JR, Bossone E, Templin C
Objective: Takotsubo syndrome (TTS) is characterized by acute left ventricular dysfunction, which can contribute to intraventricular thrombus and embolism. Still, prevalence and clinical impact of thrombus formation and embolic events on outcome of TTS patients remain unclear. This study aimed to investigate clinical features and outcomes of patients with and without intraventricular thrombus or embolism. Additionally, factors associated with thrombus formation or embolism, as well as predictors... Abstract
Journal of cardiothoracic surgery, Volume 14, Issue 1, 21 3 2019, Pages 200 Vasoresponsiveness in patients with heart failure (VASOR): protocol for a prospective observational study. van Vessem ME, Beeres SLMA, de Wilde RBP, de Vries R, Berendsen RR, de Jonge E, Danser AHJ, Klautz RJM, Schalij MJ, Palmen M
Background: Vasoplegia is a severe complication which may occur after cardiac surgery, particularly in patients with heart failure. It is a result of activation of vasodilator pathways, inactivation of vasoconstrictor pathways and the resistance to vasopressors. However, the precise etiology remains unclear. The aim of the Vasoresponsiveness in patients with heart failure (VASOR) study is to objectify and characterize the altered vasoresponsiveness in patients with heart failure, before, during... Abstract