6190 results
Cited 1 times since 2016 (0.1 per year)
source: EuropePMC
Journal of electrocardiology,
Volume 50, Issue 1, 28 4 2016, Pages 82-89
Position of ST-deviation measurements relative to the J-point: Impact for ischemia detection.
Man S, Ter Haar CC, de Jongh MC, Maan AC, Schalij MJ, Swenne CA
Background: There is no consensus about the time instant relative to the J point where ST deviation has to be measured for detection of acute ischemia in the ECG. Methods: We analyzed 53 ECGs, recorded preceding emergency catheterization of acute coronary syndrome patients with a completely occluded culprit artery (cases), and 88 control ECGs recorded in the cardiology outpatient clinic. ECG-amplitude measurements were made every 10 ms, between 20 ms before till 80 ms after the J point. STEMI-de...
Abstract
Cited 9 times since 2016 (1.1 per year)
source: Scopus
Journal of cardiovascular computed tomography,
Volume 11, Issue 1, 25 4 2016, Pages 1-7
Prognostic implications of descending thoracic aorta dilation after surgery for aortic dissection.
Regeer MV, Martina B, Versteegh MI, de Weger A, Klautz RJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Background: The present study assessed whether descending thoracic aorta growth can be measured reliably by volumetric analysis using multi-detector row computed tomography (MDCT) and whether growth influences the need for future aortic interventions in survivors of acute type A aortic dissection. Methods: A total of 51 patients (58 ± 11 years, 61% male) who underwent surgery for type A aortic dissection with ≥2 postoperative MDCT scans ≥5 months apart were included. Volumetric analysis of the d...
Abstract
JACC. Cardiovascular imaging,
Volume 10, Issue 5, 12 2 2016, Pages 523-525
Implementing Quality Control of LV Longitudinal Strain Measurement.
Delgado V, Ajmone Marsan N
Abstract
Cited 1 times since 2016 (0.1 per year)
source: EuropePMC
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG,
Volume 33, Issue 3, 7 1 2016, Pages 253-257
GSTT1 and GSTM1 gene polymorphisims in sarcoidosis.
Coskun F, Karkucak M, Yilmaz D, Yakut T, Uzaslan E
Introduction: Sarcoidosis is a granulomatous disease of unknown cause, which affects all systems, especially the lungs and the lymphatic system. Genetic and environmental factors are held accountable for the etiology. Based on the general opinion, sarcoidosis develops after exposure to a specific environmental agent by genetically susceptible individuals. The present study aimed to evaluate the disease susceptibility of the GSTT1 and GSTM1 gene polymorphisms in the patients with sarcoidosis. Me...
Abstract
Cited 166 times since 2016 (19.3 per year)
source: EuropePMC
Nature neuroscience,
Volume 19, Issue 12, 3 1 2016, Pages 1569-1582
Novel genetic loci underlying human intracranial volume identified through genome-wide association.
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, Pütz B, Ra
Intracranial volume reflects the maximally attained brain size during development, and remains stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain largely undetermined. In a genome-wide association study of 32,438 adults, we discovered five previously unknown loci for intracranial volume and confirmed two known signals. Four of the loci were also associated with adult human stature, but these remained associated with intracranial volume after adjustin...
Abstract
Cited 46 times since 2016 (5.4 per year)
source: EuropePMC
Giornale italiano di cardiologia (2006),
Volume 17, Issue 10, 1 1 2016, Pages 831-872
[2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC)].
Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, Bax JJ, Borger MA, Brotons C, Chew DP, Gencer B, Hasenfuss G, Kjeldsen K, Lancellotti P, Landmesser U, Mehilli J, Mukherjee D, Storey RF, Windecker S
Abstract
Cited 66 times since 2016 (7.7 per year)
source: EuropePMC
Current opinion in lipidology,
Volume 27, Issue 5, 1 1 2016, Pages 499-506
Plaque angiogenesis and its relation to inflammation and atherosclerotic plaque destabilization.
de Vries MR, Quax PH
Purpose of review: The review discusses the recent literature on plaque angiogenesis and its relation to inflammation and plaque destabilization. Furthermore, it discusses how plaque angiogenesis can be used to monitor atherosclerosis and serve as a therapeutic target. Recent findings: Histopathologic studies have shown a clear relationship between plaque angiogenesis, intraplaque hemorrhage (IPH), plaque vulnerability, and cardiovascular events. Hypoxia is a main driver of plaque angiogenesis a...
Abstract
Cited 38 times since 2016 (4.4 per year)
source: EuropePMC
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin,
Volume 21, Issue 42, 1 1 2016
Prolonged colonisation with Escherichia coli O25:ST131 versus other extended-spectrum beta-lactamase-producing E. coli in a long-term care facility with high endemic level of rectal colonisation, the Netherlands, 2013 to 2014.
Overdevest I, Haverkate M, Veenemans J, Hendriks Y, Verhulst C, Mulders A, Couprie W, Bootsma M, Johnson J, Kluytmans J
The extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli clone ST131 (ESBL-ST131) has spread in healthcare settings worldwide. The reasons for its successful spread are unknown, but might include more effective transmission and/or longer persistence. We evaluated the colonisation dynamics of ESBL-producing E. coli (ESBL-EC), including ESBL-ST131, in a long-term care facility (LTCF) with an unusually high prevalence of rectal ESBL-EC colonisation. During a 14-month period, rectal or...
Abstract
Cited 11 times since 2016 (1.3 per year)
source: EuropePMC
The American journal of cardiology,
Volume 119, Issue 1, 30 5 2016, Pages 1-6
Influence of Myocardial Ischemia Extent on Left Ventricular Global Longitudinal Strain in Patients After ST-Segment Elevation Myocardial Infarction.
Dimitriu-Leen AC, Scholte AJ, Katsanos S, Hoogslag GE, van Rosendael AR, van Zwet EW, Bax JJ, Delgado V
Two-dimensional echocardiographic left ventricular (LV) global longitudinal strain (GLS) after ST-segment elevation myocardial infarction (STEMI) is moderately correlated with infarct size and reflects the residual LV systolic function. This correlation may be influenced by the presence of myocardial ischemia. The present study investigated how myocardial ischemia modulates the correlation between LV GLS and infarct size determined with single-photon emission computed tomography (SPECT) myocardi...
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 24, Issue 1, 26 4 2016, Pages 174-179
Multimodality Imaging: Bird's-Eye View from the 65th Annual Scientific Sessions of the American College of Cardiology, Chicago, Ill, April 2-4, 2016.
VanDecker WA, Bax JJ, Lloyd SG, Garcia MJ, Chaudhry FA, Blankstein R
Abstract
Cited 14 times since 2016 (1.6 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 153, Issue 4, 23 4 2016, Pages 845-852
Right ventricular dysfunction affects survival after surgical left ventricular restoration.
Couperus LE, Delgado V, Palmen M, van Vessem ME, Braun J, Fiocco M, Tops LF, Verwey HF, Klautz RJ, Schalij MJ, Beeres SL
Objective: Several clinical and left ventricular parameters have been associated with prognosis after surgical left ventricular restoration in patients with ischemic heart failure. The aim of this study was to determine the prognostic value of right ventricular function. Methods: A total of 139 patients with ischemic heart failure (62 ± 10 years; 79% were male; left ventricular ejection fraction 27% ± 7%) underwent surgical left ventricular restoration. Biventricular function was assessed with e...
Abstract
Cited 439 times since 2016 (51 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 50, Issue 5, 23 4 2016, Pages e1-e88
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS.
Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, Castella M, Diener HC, Heidbuchel H, Hendriks J, Hindricks G, Manolis AS, Oldgren J, Popescu BA, Schotten U, Van Putte B, Vardas P, Agewall S, Camm J, Baron Esquivias G, Budts W, Carerj S, Casselman F, Coca A, De Caterina R, Deftereos S, Dobrev D, Ferro JM, Filippatos G, Fitzsimons D, Gorenek B, Guenoun M, Hohnloser SH, Kolh P, Lip GY, Manolis A, McMurray J, Ponikowski P, Rosenhek R, Ruschitzka F, Savelieva I, Sharma S, Suwalski P, Tamargo JL, Taylor CJ, Van Gelder IC, Voors AA, Windecker S, Zamorano JL, Zeppenfeld K
Abstract
Cited 7 times since 2016 (0.8 per year)
source: EuropePMC
Pharmacogenomics,
Volume 17, Issue 15, 20 3 2016, Pages 1621-1628
Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment.
Smit RA, Postmus I, Trompet S, Barnes MR, Warren H, Arsenault BJ, Chasman DI, Cupples LA, Hitman GA, Krauss RM, Li X, Psaty BM, Stein CM, Rotter JI, Jukema JW
Aims: To utilize previously reported lead SNPs for low-density lipoprotein cholesterol (LDL-c) levels to find additional loci of importance to statin response, and examine whether genetic predisposition to LDL-c levels associates with differential statin response. Methods: We investigated effects on statin response of 59 LDL-c SNPs, by combining summary level statistics from the Global Lipids Genetics and Genomic Investigation of Statin Therapy consortia. Results: Lead SNPs for APOE, SORT1 and N...
Abstract
Cited 9 times since 2016 (1 per year)
source: EuropePMC
Developmental dynamics : an official publication of the American Association of Anatomists,
Volume 245, Issue 11, 18 3 2016, Pages 1107-1123
14-3-3epsilon controls multiple developmental processes in the mouse heart.
Gittenberger-de Groot AC, Hoppenbrouwers T, Miquerol L, Kosaka Y, Poelmann RE, Wisse LJ, Yost HJ, Jongbloed MR, Deruiter MC, Brunelli L
Background: 14-3-3ε plays an important role in the maturation of the compact ventricular myocardium by modulating the cardiomyocyte cell cycle via p27kip1 . However, additional cardiac defects are possible given the ubiquitous expression pattern of this protein. Results: Germ line deletion of 14-3-3ε led to malalignment of both the outflow tract (OFT) and atrioventricular (AV) cushions, with resulting tricuspid stenosis and atresia, mitral valve abnormalities, and perimembranous ventricular sept...
Abstract
Cited 11 times since 2016 (1.3 per year)
source: EuropePMC
International journal of cardiology,
Volume 224, 17 3 2016, Pages 328-334
Histological evaluation disqualifies IMT and calcification scores as surrogates for grading coronary and aortic atherosclerosis.
Meershoek A, van Dijk RA, Verhage S, Hamming JF, van den Bogaerdt AJ, Bogers AJ, Schaapherder AF, Lindeman JH
Background/objectives: Carotid intimal media thickness (IMT) and coronary calcium scores (CCS) are thought to reflect atherosclerotic burden. The validity of this assumption for IMT is challenged by recent meta-analyses; for CCS by absence of a relationship between negative scores, and freedom of future events. As such, we considered evaluation of the relationship between tissue IMT and CCS, and extend of atherosclerotic disease relevant. Methods: Analyses were performed on donor aortas obtained...
Abstract
Cited 15 times since 2016 (1.7 per year)
source: EuropePMC
Circulation,
Volume 134, Issue 16, 14 2 2016, Pages 1163-1175
Thoracic Epidural Anesthesia Reduces Right Ventricular Systolic Function With Maintained Ventricular-Pulmonary Coupling.
Wink J, de Wilde RB, Wouters PF, van Dorp EL, Veering BT, Versteegh MI, Aarts LP, Steendijk P
Background: Blockade of cardiac sympathetic fibers by thoracic epidural anesthesia may affect right ventricular function and interfere with the coupling between right ventricular function and right ventricular afterload. Our main objectives were to study the effects of thoracic epidural anesthesia on right ventricular function and ventricular-pulmonary coupling. Methods: In 10 patients scheduled for lung resection, right ventricular function and its response to increased afterload, induced by te...
Abstract
Cited 210 times since 2016 (24.3 per year)
source: EuropePMC
Nature genetics,
Volume 48, Issue 10, 12 2 2016, Pages 1151-1161
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, Freitag DF, Ferreira T, Giannakopoulou O, Tinker A, Harakalova M, Mihailov E, Liu C, Kraja AT, Fallgaard Nielsen S, Rasheed A, Samuel M, Zhao W, Bonnycastle LL, Jackson AU, Narisu N, Swift AJ, Southam L, Marten J, Huyghe JR, Stančáková A, Fava C, Ohlsson T, Matchan A, Stirrups KE, Bork-Jensen J, Gjesing AP, Kontto J, Perola M, Shaw-Hawkins S, Havulinna AS, Zhang H, Donnelly LA, Groves CJ, Rayner NW, Neville MJ, Robertson NR, Yiorkas AM, Herzig KH, Kajantie E, Zhang W, Willems SM, Lannfelt L, Malerba G, Soranzo N, Trabetti E, Verweij N, Evangelou E, Moayyeri A, Vergnaud AC, Nelson CP, Poveda A, Varga TV, Caslake M, de Craen AJ, Trompet S, Luan J, Scott RA, Harris SE, Liewald DC, Marioni R, Menni C, Farmaki AE, Hallmans G, Renström F, Huffman JE, Hassinen M, Burgess S, Vasan RS, Felix JF, CHARGE-Heart Failure Consortium, Uria-Nickelsen M, Malarstig A,
High blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we genotyped 242,296 rare, low-frequency and common genetic variants in up to 192,763 individuals and used ∼155,063 samples for independent replication. We identified 30 new blood pressure- or hypertension-associated genetic regions in the general population, including 3 rare miss...
Abstract
Cited 9 times since 2016 (1 per year)
source: EuropePMC
American journal of physiology. Heart and circulatory physiology,
Volume 311, Issue 4, 9 2 2016, Pages H1014-H1023
Hyperaldosteronism induces left atrial systolic and diastolic dysfunction.
Reil JC, Tauchnitz M, Tian Q, Hohl M, Linz D, Oberhofer M, Kaestner L, Reil GH, Thiele H, Steendijk P, Böhm M, Neuberger HR, Lipp P
Patients with hypertension and hyperaldosteronism show an increased risk of stroke compared with patients with essential hypertension. Aim of the study was to assess the effects of aldosterone on left atrial function in rats as a potential contributor to thromboembolism. Osmotic mini-pumps delivering 1.5 μg aldosterone/h were implanted in rats subcutaneously (Aldo, n = 39; controls, n = 38). After 8 wk, left ventricular pressure-volume analysis of isolated working hearts was performed, and left...
Abstract
Journal of electrocardiology,
Volume 50, Issue 1, 8 2 2016, Pages 115-122
Detection of elevated pulmonary pressures by the ECG-derived ventricular gradient: A comparison of conversion matrices in patients with suspected pulmonary hypertension.
Haeck ML, Kapel GF, Scherptong RW, Swenne CA, Maan AC, Bax JJ, Schalij MJ, Vliegen HW
Background: The aim was to assess the diagnostic value of the Inverse Dower (INVD)-derived vectorcardiogram (VCG) and the Kors-derived VCG to detect elevated systolic pulmonary artery pressure (SPAP) in suspected pulmonary hypertension (PH). Methods: In 132 patients, morphologic variables were evaluated by comparing the VCG parameters synthesized by INVD and Kors matrix. Comparison of the diagnostic accuracy of detecting SPAP ≥50mmHg between the matrices was performed by ROC curve analysis and l...
Abstract
Cited 54 times since 2016 (6.2 per year)
source: EuropePMC
The Journal of clinical endocrinology and metabolism,
Volume 101, Issue 11, 7 1 2016, Pages 4270-4282
Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis.
Chaker L, Baumgartner C, den Elzen WP, Collet TH, Ikram MA, Blum MR, Dehghan A, Drechsler C, Luben RN, Portegies ML, Iervasi G, Medici M, Stott DJ, Dullaart RP, Ford I, Bremner A, Newman AB, Wanner C, Sgarbi JA, Dörr M, Longstreth WT, Psaty BM, Ferrucci L, Maciel RM, Westendorp RG, Jukema JW, Ceresini G, Imaizumi M, Hofman A, Bakker SJ, Franklyn JA, Khaw KT, Bauer DC, Walsh JP, Razvi S, Gussekloo J, Völzke H, Franco OH, Cappola AR, Rodondi N, Peeters RP, Thyroid Studies Collaboration
Context: The currently applied reference ranges for thyroid function are under debate. Despite evidence that thyroid function within the reference range is related with several cardiovascular disorders, its association with the risk of stroke has not been evaluated previously. Design and setting: We identified studies through a systematic literature search and the Thyroid Studies Collaboration, a collaboration of prospective cohort studies. Studies measuring baseline TSH, free T4, and stroke out...
Abstract
