6555 results
Cited 41 times since 2007 (2.4 per year)
source: EuropePMC
Journal of clinical pharmacology,
Volume 47, Issue 12, 1 1 2007, Pages 1555-1569
A randomized, placebo-controlled trial to evaluate the efficacy, safety, and pharmacodynamic interaction of coadministered amlodipine and atorvastatin in 1660 patients with concomitant hypertension and dyslipidemia: the respond trial.
Preston RA, Harvey P, Herfert O, Dykstra G, Jukema JW, Sun F, Gillen D
Guidelines stress the importance of the simultaneous management of multiple cardiovascular risk factors. This can in part be achieved by coadministration of lipid-lowering and antihypertensive treatments. Potential pharmacodynamic interaction between drugs should be investigated as part of developing single-pill combinations. The Respond trial assessed whether combining amlodipine to treat hypertension and atorvastatin to treat dyslipidemia affected the action of either monotherapy. A total of 1...
Abstract
Cited 21 times since 2007 (1.2 per year)
source: EuropePMC
Journal of hypertension,
Volume 25, Issue 12, 1 1 2007, Pages 2454-2462
Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice.
van der Hoorn JW, Kleemann R, Havekes LM, Kooistra T, Princen HM, Jukema JW
Aim: This study was designed to investigate the effect of the angiotensin II receptor blocker olmesartan alone, or in combination with standard treatment with a statin, pravastatin, on atherosclerosis development in APOE*3Leiden transgenic mice. Methods and results: Four groups of 15 mice received an atherogenic diet alone (plasma cholesterol 17.4 +/- 2.7 mmol/l) or supplemented with either 0.008% (w/w) olmesartan (9.3 mg/kg per day) (plasma cholesterol 16.4 +/- 3.9 mmol/l), 0.03% (w/w) pravasta...
Abstract
Clinical nuclear medicine,
Volume 32, Issue 12, 1 1 2007, Pages 927-929
Intermittent ST-segment depressions during adenosine stress test.
van der Hiel B, Scholte AJ, Stokkel MP
ST-segment depression during adenosine stress testing is usually a 1-time event during or after the test and is often related to ischemia due to severe 3-vessel disease. In this case report we describe a patient with severe 3-vessel disease who had intermittent ST-segment depression on the electrocardiogram during a myocardial perfusion stress test with adenosine. These intermittent ST depressions could be explained by possible adenosine-induced coronary spasm.
Abstract
Cited 24 times since 2007 (1.4 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 48, Issue 12, 1 1 2007, Pages 2001-2010
Nuclear imaging in cardiac resynchronization therapy.
Henneman MM, van der Wall EE, Ypenburg C, Bleeker GB, van de Veire NR, Marsan NA, Chen J, Garcia EV, Westenberg JJ, Schalij MJ, Bax JJ
Recently, cardiac resynchronization therapy (CRT) has become implemented in the treatment of patients with severe heart failure. Although the improvement in systolic function after CRT implantation can be considerable, 20%-30% of patients do not respond to CRT. Evidence is accumulating that the presence of left ventricular (LV) dyssynchrony is mandatory for a response to CRT. Since the early 1980s attempts have been made to assess cardiac dyssynchrony with nuclear imaging, and it has been report...
Abstract
Cited 6 times since 2007 (0.3 per year)
source: EuropePMC
Thrombosis and haemostasis,
Volume 98, Issue 6, 1 1 2007, Pages 1323-1328
The influence of established genetic variation in the haemostatic system on clinical restenosis after percutaneous coronary interventions.
Pons D, Monraats PS, de Maat MP, Pires NM, Quax PH, van Vlijmen BJ, Rosendaal FR, Zwinderman AH, Doevendans PA, Waltenberger J, de Winter RJ, Tio RA, Frants RR, van der Laarse A, van der Wall EE, Jukema JW
Since activation of the haemostatic system is an important feature of the wound healing response triggered by arterial injury, variations in genes involved in thrombus formation may play a role in restenosis after percutaneous coronary interventions (PCI). Therefore, our aim was to examine the relationship between polymorphisms that are known to play a role in the haemostatic system and the risk of clinical restenosis in the GENetic DEterminants of Restenosis (GENDER) study, a multicenter prospe...
Abstract
Journal of the American College of Cardiology,
Volume 50, Issue 24, 26 4 2007, Pages 2336-2343
Highlights of the 2007 scientific sessions of the American Society of Nuclear Cardiology San Diego, California, September 6-9, 2007.
Russell RR, Abbott BG, Arrighi JA, Bengel FM, Cohen MC, Garcia EV, Hendel RC, Holly TA, Mieres JH, Shaw LJ, Thomas GS, Thompson RC, Wackers FJ, Bax JJ
Abstract
Cited 38 times since 2007 (2.2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 101, Issue 1, 26 4 2007, Pages 40-45
Anatomic correlates of a normal perfusion scan using 64-slice computed tomographic coronary angiography.
van Werkhoven JM, Schuijf JD, Jukema JW, Kroft LJ, Stokkel MP, Dibbets-Schneider P, Pundziute G, Scholte AJ, van der Wall EE, Bax JJ
Both myocardial perfusion imaging (MPI) and multislice computed tomography (MSCT) are currently used to detect coronary artery disease (CAD). However, MSCT permits early detection of atherosclerosis while myocardial perfusion is still normal. In addition, MPI results can be normal despite the presence of high-risk CAD (left main and balanced 3-vessel CAD). In this study, the range of anatomic findings using MSCT in patients with normal MPI results was evaluated. In 180 patients presenting with c...
Abstract
Journal of cardiovascular electrophysiology,
Volume 19, Issue 2, 20 3 2007, Pages 133-135
The role of positron emission tomography in evaluation of alterations in cardiac efficiency after cardiac resynchronization therapy.
Ypenburg C, Bax JJ
Abstract
Cited 230 times since 2007 (13.3 per year)
source: EuropePMC
Circulation research,
Volume 102, Issue 2, 15 3 2007, Pages 257-264
Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction.
Timmers L, Sluijter JP, van Keulen JK, Hoefer IE, Nederhoff MG, Goumans MJ, Doevendans PA, van Echteld CJ, Joles JA, Quax PH, Piek JJ, Pasterkamp G, de Kleijn DP
Left ventricular (LV) remodeling leads to congestive heart failure and is a main determinant of morbidity and mortality following myocardial infarction. Therapeutic options to prevent LV remodeling are limited, which necessitates the exploration of alternative therapeutic targets. Toll-like receptors (TLRs) serve as pattern recognition receptors within the innate immune system. Activation of TLR4 results in an inflammatory response and is involved in extracellular matrix degradation, both key pr...
Abstract
Cited 10 times since 2007 (0.6 per year)
source: EuropePMC
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
Volume 23, Issue 2, 14 2 2007, Pages 601-607
Prognostic significance of renal function in patients undergoing dobutamine stress echocardiography.
Karagiannis SE, Feringa HH, Elhendy A, van Domburg R, Chonchol M, Vidakovic R, Bax JJ, Karatasakis G, Athanasopoulos G, Cokkinos DV, Poldermans D
Background: Dobutamine stress echocardiography (DSE) is used for risk stratification of patients with suspected coronary artery disease (CAD). However, the prognostic value of DSE among the entire strata of renal function has yet to be determined. We assessed the prognostic value of renal function relative to DSE findings. Methods: We studied 2292 patients, divided into 729 (32%) patients with normal renal function [creatinine clearance (CrCl) >90 ml/min] and 1563 (68%) with renal dysfunction...
Abstract
Cited 87 times since 2007 (5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 50, Issue 21, 7 1 2007, Pages 2071-2077
Acute effects of initiation and withdrawal of cardiac resynchronization therapy on papillary muscle dyssynchrony and mitral regurgitation.
Ypenburg C, Lancellotti P, Tops LF, Bleeker GB, Holman ER, Piérard LA, Schalij MJ, Bax JJ
Objectives: The purpose of this study was to evaluate the relationship between dyssynchrony involving the mitral valve apparatus and the acute improvement in mitral regurgitation (MR) after cardiac resynchronization therapy (CRT). The effect of interruption of CRT at 6 months' follow-up on dyssynchrony and MR was also evaluated. Background: Mitral regurgitation may improve acutely after CRT, but the precise mechanism is not fully understood. Methods: Out of 63 consecutive patients with base...
Abstract
Cited 19 times since 2007 (1.1 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 94, Issue 3, 5 1 2007, Pages e9
Triplane tissue Doppler imaging: a novel three-dimensional imaging modality that predicts reverse left ventricular remodelling after cardiac resynchronisation therapy.
Van de Veire NR, Yu CM, Ajmone-Marsan N, Bleeker GB, Ypenburg C, De Sutter J, Zhang Q, Fung JW, Chan JY, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
Background: Several two-dimensional (2-D) tissue Doppler imaging (TDI) echocardiographic techniques have proved useful to identify responders to cardiac resynchronisation therapy (CRT). Recently a 3-D probe allowing simultaneous acquisition of TDI data in three imaging planes became available. Objective: To evaluate the value of triplane TDI to predict reverse left ventricular (LV) remodelling after CRT. Methods: Sixty patients with heart failure, scheduled for CRT, underwent triplane echocardio...
Abstract
Cited 10 times since 2007 (0.6 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 21, Issue 5, 1 1 2007, Pages 512.e5-7
Iatrogenic perforation of the posterior mitral valve leaflet: a rare complication of pacemaker lead placement.
Konings TC, Koolbergen DR, Bouma BJ, Groenink M, Mulder BJ
An inadvertently placed pacing lead in the left ventricle (LV) is a rare and often underdiagnosed complication of pacemaker implantation. We present a case of a 73-year-old woman who was evaluated for dyspnea, 10 years after transvenous pacemaker implantation. Transthoracic and transesophageal echocardiography revealed a secundum atrial septal defect through which the ventricular pacing lead was placed into the LV. Whereas percutaneous extraction of the lead seemed too full of risk, the patient...
Abstract
Cited 1 times since 2007 (0.1 per year)
source: EuropePMC
Clinical nuclear medicine,
Volume 32, Issue 11, 1 1 2007, Pages 835-838
Reliability of bone scintigraphy for suspected scaphoid fractures.
Beeres FJ, Hogervorst M, Rhemrev SJ, Le Cessie S, Arndt JW, Stokkel MP, Bartlema KA, Hamming JF
Purpose: To examine the observer variation for bone scintigraphy in the detection of occult scaphoid fractures in daily practice, using only the early bone scanning images. Methods: One hundred bone scans of patients with a suspected scaphoid fracture but negative initial radiographs were prospectively included to calculate the inter- and intraobserver variation. Three nuclear medicine physicians independently evaluated all bone scans at 2 different points in time with a 3-month interval. The ob...
Abstract
Cited 7 times since 2007 (0.4 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 21, Issue 6, 1 1 2007, Pages 780-789
Glycemic control, lipid-lowering treatment, and prognosis in diabetic patients with peripheral atherosclerotic disease.
Feringa HH, Karagiannis SE, Vidakovic R, Elhendy A, Schouten O, Boersma E, Bax JJ, Poldermans D
Glycemic control may be an underestimated risk factor in diabetic patients with peripheral arterial disease (PAD). Chronic statin therapy may improve glycemic control and outcome in these patients. In an observational cohort study of 425 consecutive diabetic patients with PAD, chronic statin therapy was noted, the ankle-brachial index was measured, and serial glycemic hemoglobin (HbA(1c)) measurements were obtained. During follow-up (median 7 years), all-cause mortality and cardiac death occurre...
Abstract
Cited 14 times since 2007 (0.8 per year)
source: EuropePMC
American heart journal,
Volume 154, Issue 5, 1 1 2007, Pages 954-961
Statin therapy is associated with improved outcomes in vascular surgery patients with renal impairment.
Welten GM, Chonchol M, Hoeks SE, Schouten O, Dunkelgrün M, van Gestel YR, Goei D, Bax JJ, van Domburg RT, Poldermans D
Background: Little is known about the association between baseline kidney function, statin therapy, and outcome after vascular surgery in patients with and without chronic kidney disease. Methods: A total of 2126 patients underwent elective major vascular surgery and were divided into 2 categories based on baseline creatinine clearance (CrCl), calculated using the Cockcroft-Gault equation: CrCl > or = 60 mL/min (n = 1358, reference) and CrCl < 60 mL/min (n = 768). Outcome measures were 30-...
Abstract
Cited 19 times since 2007 (1.1 per year)
source: EuropePMC
Coronary artery disease,
Volume 18, Issue 7, 1 1 2007, Pages 571-576
The prevalence and prognosis of unrecognized myocardial infarction and silent myocardial ischemia in patients undergoing major vascular surgery.
Feringa HH, Karagiannis SE, Vidakovic R, Elhendy A, ten Cate FJ, Noordzij PG, van Domburg RT, Bax JJ, Poldermans D
Objective: The aim of this study is to determine the prevalence and prognosis of unrecognized myocardial infarction (MI) and silent myocardial ischemia in vascular surgery patients. Methods: In a cohort of 1092 patients undergoing preoperative dobutamine stress echocardiography and noncardiac vascular surgery, unrecognized MI was determined by rest wall motion abnormalities in the absence of a history of MI. Silent myocardial ischemia was determined by stress-induced wall motion abnormalities in...
Abstract
Cited 359 times since 2007 (20.7 per year)
source: EuropePMC
Stem cell research,
Volume 1, Issue 2, 1 1 2007, Pages 129-137
Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium.
Timmers L, Lim SK, Arslan F, Armstrong JS, Hoefer IE, Doevendans PA, Piek JJ, El Oakley RM, Choo A, Lee CN, Pasterkamp G, de Kleijn DP
Although paracrine effects of mesenchymal stem cells (MSCs) have been suggested previously, cardioprotection by human MSC secretions has never been demonstrated. Human MSC-conditioned medium (CM) was collected by following a clinically compliant protocol. In a porcine model of ischemia and reperfusion injury, intravenous and intracoronary MSC-CM treatment significantly reduced myocardial nuclear oxidative stress as determined by immunostaining for 8-hydroxy-2'-deoxyguanosine. In addition, e...
Abstract
Cited 83 times since 2007 (4.8 per year)
source: EuropePMC
Journal of the American Geriatrics Society,
Volume 55, Issue 11, 1 1 2007, Pages 1777-1785
Association between apolipoprotein E4 and cognitive decline in elderly adults.
Packard CJ, Westendorp RG, Stott DJ, Caslake MJ, Murray HM, Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Cobbe SM, Ford I, Gaw A, Hyland M, Jukema JW, Kamper AM, Macfarlane PW, Jolles J, Perry IJ, Sweeney BJ, Twomey C, Prospective Study of Pravastatin in the Elderly at Risk Group
Objective: To determine the influence of apolipoprotein E on cognitive decline in a cohort of elderly men and women. Design: Prospective study. Setting: Scotland, Ireland, and the Netherlands. Participants: Five thousand eight hundred four subjects aged 70 to 82 from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Measurements: Subjects were assessed at baseline and over a mean 3.2-year (range 0.7-4.2) follow-up for memory (Picture-Word Recall), speed of information proces...
Abstract
Cited 23 times since 2007 (1.3 per year)
source: EuropePMC
International journal of cardiology,
Volume 131, Issue 2, 1 1 2007, Pages 285-287
Effect of EPO administration on myocardial infarct size in patients with non-STE acute coronary syndromes; results from a pilot study.
Liem A, van de Woestijne AP, Bruijns E, Roeters van Lennep HW, de Boo JA, van Halteren HK, van Es TP, Jukema JW, van der Laarse A, Zwinderman AH, van Veldhuisen DJ
A pilot study was performed to determine the effect of 40,000 IU Epo on myocardial damage in 51 patients with non-ST segment elevation acute coronary syndrome (non-STE ACS). No significant difference in myocardial damage was found, but an increased systolic blood pressure was noticed.
Abstract
