6190 results
Cited 140 times since 2003 (6.6 per year)
source: EuropePMC
Circulation,
Volume 109, Issue 3, 29 5 2004, Pages 393-398
Toll-like receptor 4 is involved in outward arterial remodeling.
Hollestelle SC, De Vries MR, Van Keulen JK, Schoneveld AH, Vink A, Strijder CF, Van Middelaar BJ, Pasterkamp G, Quax PH, De Kleijn DP
Background: Toll-like receptor 4 (Tlr4) is the receptor for exogenous lipopolysaccharides (LPS). Expression of endogenous Tlr4 ligands, heat shock protein 60 (Hsp60) and extra domain A of fibronectin, has been observed in arthritic and oncological specimens in which matrix turnover is an important feature. In atherosclerosis, outward remodeling is characterized by matrix turnover and a structural change in arterial circumference and is associated with a vulnerable plaque phenotype. Since Tlr4 li...
Abstract
Cited 2 times since 2003 (0.1 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 19, Issue 6, 1 1 2003, Pages 529-531
Viability assessment: nuclear imaging vs. dobutamine echocardiography.
Bax JJ, van der Wall EE
Abstract
Cited 41 times since 2003 (1.9 per year)
source: EuropePMC
European journal of heart failure,
Volume 5, Issue 6, 1 1 2003, Pages 767-774
Screening for left ventricular dysfunction using a hand-carried cardiac ultrasound device.
Vourvouri EC, Schinkel AF, Roelandt JR, Boomsma F, Sianos G, Bountioukos M, Sozzi FB, Rizzello V, Bax JJ, Karvounis HI, Poldermans D
Background: The hand-carried cardiac ultrasound (HCU) device is a recently introduced imaging device, which may be potentially useful in the primary care setting. Aim: To test the screening potential of a HCU for the detection of left ventricular (LV) dysfunction by evaluating LV ejection fraction (LVEF) and inferior vena cava (IVC) collapse. Standard echocardiographic system (SE) and plasma brain natriuretic peptide (BNP) measurements were used as a reference. Methods: Eighty-eight consecutive...
Abstract
Cited 11 times since 2003 (0.5 per year)
source: EuropePMC
Nuklearmedizin. Nuclear medicine,
Volume 42, Issue 6, 1 1 2003, Pages 240-243
Iodine excretion during stimulation with rhTSH in differentiated thyroid carcinoma.
Löffler M, Weckesser M, Franzius C, Kies P, Schober O
Aim: Elevated iodine intake is a serious problem in the diagnostic and therapeutic application of (131)iodine in patients with differentiated thyroid cancer. Therefore, iodine avoidance is necessary 3 months in advance. Additionally, endogenous stimulation requires withdrawal of thyroid hormone substitution for 4 weeks. Exogenous stimulation using recombinant human TSH (rhTSH) enables the continuous substitution of levothyroxine, which contains 65.4% of its molecular weight in iodine. Thus, a su...
Abstract
Cited 5 times since 2003 (0.2 per year)
source: EuropePMC
Lancet (London, England),
Volume 362, Issue 9401, 1 1 2003, Pages 2118-9; author reply 2119-20
Selective decontamination of digestive tract in intensive care.
Bonten MJ, Kluytmans J, de Smet AM, Bootsma M, Hoes A
Abstract
Cited 37 times since 2003 (1.7 per year)
source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions,
Volume 60, Issue 4, 1 1 2003, Pages 452-457
Randomized study to compare balloon angioplasty and elective stent implantation in venous bypass grafts: the Venestent study.
Hanekamp CE, Koolen JJ, Den Heijer P, Schalij MJ, Piek JJ, Bär FW, De Scheerder I, Bonnier HJ, Pijls NH, Venestent Study Group
The aim of the study was to compare acute and long-term angiographic and clinical outcome of balloon angioplasty and elective stenting in de novo lesions in the body of a saphenous vein graft (SVG). A total of 150 patients, with de novo lesions in SVG, were randomly assigned to balloon angioplasty or elective Wiktor I stent implantation. The angiographic restenosis rate at 6-month follow-up was 32.8% in the balloon group and 19.1% in the stent group (P = 0.069). At 1-year follow-up, target vesse...
Abstract
The international journal of cardiovascular imaging,
Volume 19, Issue 6, 1 1 2003, Pages 549-552
MR imaging in arrhythmogenic right ventricular dysplasia/cardiomyopathy.
van der Wall EE, Schalij MJ
Abstract
Cited 61 times since 2003 (2.8 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 126, Issue 6, 1 1 2003, Pages 2003-2010
Decellularization of rat aortic valve allografts reduces leaflet destruction and extracellular matrix remodeling.
Grauss RW, Hazekamp MG, van Vliet S, Gittenberger-de Groot AC, DeRuiter MC
Objectives: Decellularization of aortic valve allografts in advance of transplantation is a promising approach to overcome immune-induced early graft failure. In this study the effects of in vitro cell extraction on extracellular matrix molecules and in vivo remodeling of decellularized aortic valves were investigated in a heterotopic aortic valve rat implantation model. Methods: Rat aortic valve conduits were decellularized by a 2-step detergent-enzymatic extraction method involving sodium dode...
Abstract
Cited 29 times since 2003 (1.4 per year)
source: EuropePMC
Journal of virology,
Volume 77, Issue 24, 1 1 2003, Pages 12996-13004
Intra- and intermolecular disulfide bonds of the GP2b glycoprotein of equine arteritis virus: relevance for virus assembly and infectivity.
Wieringa R, De Vries AA, Post SM, Rottier PJ
Equine arteritis virus (EAV) is an enveloped, positive-strand RNA virus belonging to the family Arteriviridae of the order NIDOVIRALES: EAV virions contain six different envelope proteins. The glycoprotein GP(5) (previously named G(L)) and the unglycosylated membrane protein M are the major envelope proteins, while the glycoproteins GP(2b) (previously named G(S)), GP(3), and GP(4) are minor structural proteins. The unglycosylated small hydrophobic envelope protein E is present in virus particles...
Abstract
Minerva cardioangiologica,
Volume 51, Issue 6, 1 1 2003, Pages 667-676
Myocardial tissue Doppler echocardiography and cardiac resynchronization therapy.
Molhoek SG, Schalij MJ, Van Der Wall EE, Bax JJ
Cardiac resynchronization therapy (CRT) is a promising technique for patients with end-stage, drug-refractory heart failure. Still 20-30% of the patients treated with CRT do not respond. Accordingly, the current selection criteria need to be refined, and it appears that demonstration of left ventricular dyssynchrony may be mandatory for response to CRT. Novel echocardiographic methods are currently investigated to detect left ventricular dyssynchrony and thereby improve the selection of candidat...
Abstract
Cited 24 times since 2003 (1.1 per year)
source: EuropePMC
The American journal of cardiology,
Volume 92, Issue 11, 1 1 2003, Pages 1267-1270
Long-term prognosis after normal dobutamine stress echocardiography.
Sozzi FB, Elhendy A, Roelandt JR, van Domburg RT, Schinkel AF, Vourvouri EC, Bax JJ, Rizzello V, Poldermans D
Patients with normal dobutamine stress echocardiography (DSE) were shown to have a favorable outcome at an intermediate-term follow-up. However, there are scarce data regarding long-term survival after normal DSE. This study sought to assess the long-term outcome after normal DSE. We studied 401 patients (age 62 +/- 10 years, 264 men) who had a normal echocardiogram at rest and with high-dose dobutamine stress. End points during a mean follow-up of 5 +/- 1.7 years (minimum 3.5) were all-cause mo...
Abstract
Cited 4 times since 2003 (0.2 per year)
source: EuropePMC
Pediatric nephrology (Berlin, Germany),
Volume 19, Issue 2, 25 4 2003, Pages 237-239
Fulminant meningococcemia and acute renal failure in a 3-year-old boy.
Akil I, Yüksel H, Coskun S, Yilmaz D, Onag A
Acute renal failure is a common occurrence in sepsis, but is rarely reported in meningococcemia. We present a young child diagnosed with fulminant meningococcemia who had several poor prognostic factors, including hypotension, thrombocytopenia, purpura fulminans, seizures, the absence of meningitis with meningococcemia, and acute renal failure, which was successfully treated with peritoneal dialysis. Peritoneal dialysis was started on the 5th day because the patient had been anuric for 48 h. At...
Abstract
Cited 51 times since 2003 (2.4 per year)
source: EuropePMC
Molecular biology of the cell,
Volume 15, Issue 2, 14 2 2003, Pages 611-624
Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes.
Fouraux MA, Deneka M, Ivan V, van der Heijden A, Raymackers J, van Suylekom D, van Venrooij WJ, van der Sluijs P, Pruijn GJ
We describe the characterization of an 80-kDa protein cross-reacting with a monoclonal antibody against the human La autoantigen. The 80-kDa protein is a variant of rabip4 with an N-terminal extension of 108 amino acids and is expressed in the same cells. For this reason, we named it rabip4'. rabip4' is a peripheral membrane protein, which colocalized with internalized transferrin and EEA1 on early endosomes. Membrane association required the presence of the FYVE domain and was perturb...
Abstract
Cited 9 times since 2003 (0.4 per year)
source: EuropePMC
The American journal of cardiology,
Volume 92, Issue 10, 1 1 2003, Pages 1165-1170
Prognostic significance of fixed perfusion abnormalities on stress technetium-99m sestamibi single-photon emission computed tomography in patients without known coronary artery disease.
Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Poldermans D
Fixed perfusion abnormalities in patients with known coronary artery disease (CAD) are associated with myocardial damage and adverse outcomes. However, the significance of these abnormalities in patients without known CAD is unclear. The aim of this study was to assess the prognostic significance of fixed versus reversible perfusion abnormalities in patients without known CAD. We studied 327 patients (58 +/- 11 years of age; 215 men) with no history of myocardial infarction or revascularization,...
Abstract
Cited 1 times since 2003 (0 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 76, Issue 5, 1 1 2003, Pages 1748
Evaluation of rerouting surgery of a coronary artery anomaly by magnetic resonance angiography.
Salm LP, Bax JJ, Lamb HJ, Hazekamp MG, de Roos A, van der Wall EE, Vliegen HW
Abstract
Cited 61 times since 2003 (2.8 per year)
source: EuropePMC
AJR. American journal of roentgenology,
Volume 181, Issue 5, 1 1 2003, Pages 1355-1359
Comparison of CT and sonography in the diagnosis of acute appendicitis: a blinded prospective study.
Poortman P, Lohle PN, Schoemaker CM, Oostvogel HJ, Teepen HJ, Zwinderman KA, Hamming JF
Objective: Our objective was to compare the accuracy of CT and sonography in a general community teaching hospital for the diagnosis of acute appendicitis in patients with suspected acute appendicitis. SUBJECTS AND METHODS. In this prospective study, 199 consecutive patients with clinical signs and symptoms of acute appendicitis were examined with sonography (graded compression technique) and CT (focused unenhanced single-detector helical CT [5-mm section thickness]. CT was performed from the L2...
Abstract
Cited 1 times since 2003 (0 per year)
source: EuropePMC
Perfusion,
Volume 18, Issue 6, 1 1 2003, Pages 357-362
Increasing the antioxidative capacity of neonatal cardiopulmonary bypass prime solution: an in vitro study.
Draaisma AM, Molicki JS, Verbeet N, Munneke R, Huysmans HA, Berger HM, Hazekamp MG
Inflammation and oxidative damage are believed to play an important role in the postoperative complications after cardiopulmonary bypass (CPB) in neonates. During the preparation of the prime, red blood cells (RBCs) release non-protein-bound iron (NPBI) and free haemoglobin/haem (Hb/haem). The presence of these prooxidants in the prime solution may increase oxidative stress in neonates undergoing CPB. The solution used as the basis of the prime solution may influence the degree of this oxidative...
Abstract
Cited 60 times since 2003 (2.8 per year)
source: EuropePMC
Archives of otolaryngology--head & neck surgery,
Volume 129, Issue 11, 1 1 2003, Pages 1225-1229
Detection of Helicobacter pylori and its CagA gene in tonsil and adenoid tissues by PCR.
Cirak MY, Ozdek A, Yilmaz D, Bayiz U, Samim E, Turet S
Objective: To determine the presence of Helicobacter pylori and, if detected, the prevalence of the CagA gene in adenotonsillectomy specimens by polymerase chain reaction (PCR). Design: A prospective clinical trial. Setting: Tertiary referral center. Patients and methods: The study population comprised 23 patients who had undergone adenoidectomy, tonsillectomy, or adenotonsillectomy under local or general anesthesia. Helicobacter pylori DNA was extracted from 3-mm-diameter tissue samples obtaine...
Abstract
Cited 295 times since 2003 (13.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 92, Issue 10, 1 1 2003, Pages 1238-1240
Left ventricular dyssynchrony predicts benefit of cardiac resynchronization therapy in patients with end-stage heart failure before pacemaker implantation.
Bax JJ, Marwick TH, Molhoek SG, Bleeker GB, van Erven L, Boersma E, Steendijk P, van der Wall EE, Schalij MJ
We evaluated patients with end-stage heart failure who have a high likelihood of response to cardiac resynchronization therapy (biventricular pacing). It appears that 20% of patients do not respond to this expensive therapy despite the use of selection criteria (dilated cardiomyopathy, heart failure, New York Heart Association class II or IV, left ventricular ejection fraction 120 ms). The presence of left ventricular dyssynchrony is needed to result in improvement after cardiac resynchronizatio...
Abstract
Cited 13 times since 2003 (0.6 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 10, Issue 6, 1 1 2003, Pages 615-622
Risk stratification of patients after myocardial revascularization by stress Tc-99m tetrofosmin myocardial perfusion tomography.
Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Valkema R, Poldermans D
Background: The aim of this study was to assess the incremental prognostic value of stress technetium 99m tetrofosmin imaging after myocardial revascularization. Methods and results: We studied 381 patients (aged 60 +/- 10 years, 270 men), 4.5 +/- 3.2 years after myocardial revascularization (coronary artery bypass grafting in 201 patients and percutaneous coronary intervention in 180 patients), who underwent exercise or dobutamine stress tetrofosmin single photon emission computed tomography. E...
Abstract
