Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7971 results
Cited 16 times since 2022 (4.9 per year) source: EuropePMC
European journal of anaesthesiology, Volume 39, Issue 3, 1 1 2022, Pages 198-209 Peri-interventional outcome study in the elderly in Europe: A 30-day prospective cohort study. POSE-Study group
Objectives: The aim of this study was to describe the 30-day mortality rate of patients aged 80 years and older undergoing surgical and nonsurgical procedures under anaesthesia in Europe and to identify risk factors associated with mortality. Design: A prospective cohort study. Setting: European multicentre study, performed from October 2017 to December 2018. Centres committed to a 30-day recruitment period within the study period. Patients: Nine thousand four hundred and ninety-seven consecutiv... Abstract
Cited 3 times since 2022 (0.9 per year) source: EuropePMC
European heart journal, Volume 43, Issue 13, 1 1 2022, Pages 1288-1295 The year in cardiovascular medicine 2021: imaging. Bucciarelli-Ducci C, Ajmone-Marsan N, Di Carli M, Nicol E
This article reviews the most relevant literature published in 2021 on the role of cardiovascular imaging in cardiovascular medicine. Coronavirus disease 2019 (COVID-19) continued to impact the healthcare landscape, resulting in reduced access to hospital-based cardiovascular care including reduced routine diagnostic cardiovascular testing. However, imaging has also facilitated the understanding of the presence and extent of myocardial damage caused by the coronavirus infection. What has dominat... Abstract
Cited 2 times since 2022 (0.6 per year) source: EuropePMC
Biomedicines, Volume 10, Issue 3, 28 4 2022, Pages 565 Blood M2-like Monocyte Polarization Is Associated with Calcific Plaque Phenotype in Stable Coronary Artery Disease: A Sub-Study of SMARTool Clinical Trial. Sbrana S, Cecchettini A, Bastiani L, Di Giorgi N, Mazzone A, Ceccherini E, Vozzi F, Caselli C, Neglia D, Clemente A, Scholte AJHA, Parodi O, Pelosi G, Rocchiccioli S
Background: Atherosclerosis is a chronic inflammatory disease. The balance between pro- and anti-inflammatory factors, acting on the arterial wall, promotes less or more coronary plaque macro-calcification, respectively. We investigated the association between monocyte phenotypic polarization and CTCA-assessed plaque dense-calcium volume (DCV) in patients with stable coronary artery disease (CAD). Methods: In 55 patients, individual DCV component was assessed by quantitative CTCA and normalized... Abstract
Cited 8 times since 2022 (2.5 per year) source: EuropePMC
The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, Volume 21, Issue 1, 28 4 2022, Pages 1-7 Exploring the surgical personality. Sier VQ, Schmitz RF, Schepers A, van der Vorst JR
Surgery is a demanding field, requiring determination and emotional stability. This review explores the surgical personality, addressing international personality differences between surgical and non-surgical specialties. Across the globe, surgically-interested individuals (i.e., medical students, residents, surgeons) generally scored higher on conscientiousness, open mindedness, and extraversion, and lower on neuroticism compared to non-surgically-interested contemporaries. Extraversion was inv... Abstract
Cited 13 times since 2022 (4 per year) source: EuropePMC
Microbiology spectrum, Volume 10, Issue 2, 28 4 2022, Pages e0213421 Phenotypic and Genotypic Characterization of a Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae ST17-KL38 Clinical Isolate Harboring the Carbapenemase IMP-4. He J, Du X, Zeng X, Moran RA, van Schaik W, Zou Q, Yu Y, Zhang J, Hua X
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) is a threat to global public health. We characterized a sequence type 17 (ST17) K. pneumoniae clinical isolate that was resistant to carbapenems and belonged to serotype KL38/O2. Its complete genome is comprised of a 5.1-Mb chromosome and two conjugative plasmids. The 52,578-bp N-type plasmid pXH210-IMP contains the blaIMP-4 carbapenemase gene and the quinolone resistance gene qnrS1. The 272,742-bp FII(K)-9:FIB(K)-10 plasmid pXH2... Abstract
The international journal of cardiovascular imaging, Volume 38, Issue 5, 26 4 2022, Pages 927-929 Patterns of cardiac involvement characterized by strain echocardiography in amyloidosis. Tjahjadi C, Fortuni F, Stassen J, Marsan NA, Delgado V, Bax JJ
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 30, Issue 6, 24 4 2022, Pages 338-339 Multiple culprit lesions in ST-segment elevation myocardial infarction with cardiogenic shock: a case of simultaneous thrombosis of two infarct-related arteries. Caliskan R, Ince H, Arslan F
Cited 2 times since 2022 (0.6 per year) source: EuropePMC
British journal of pharmacology, Volume 179, Issue 13, 23 4 2022, Pages 3382-3402 In vivo and cellular antiarrhythmic and cardiac electrophysiological effects of desethylamiodarone in dog cardiac preparations. Kohajda Z, Virág L, Hornyik T, Husti Z, Sztojkov-Ivanov A, Nagy N, Horváth A, Varga R, Prorok J, Szlovák J, Tóth N, Gazdag P, Topal L, Naveed M, Árpádffy-Lovas T, Pászti B, Magyar T, Koncz I, Déri S, Demeter-Haludka V, Aigner Z, Ördög B, Patfalusi M, Tálosi L, Tiszlavicz L, Földesi I, Jost N, Baczkó I, Varró A
Background and purpose: The aim of the present study was to study the antiarrhythmic effects and cellular mechanisms of desethylamiodarone (DEA), the main metabolite of amiodarone (AMIO), following acute and chronic 4-week oral treatments (25-50 mg·kg-1 ·day-1 ). Experimental approach: The antiarrhythmic effects of acute iv. (10 mg·kg-1 ) and chronic oral (4 weeks, 25 mg·kg-1 ·day-1 ) administration of DEA were assessed in carbachol and tachypacing-induced dog atrial fibrillation models. Action... Abstract
Cited 11 times since 2022 (3.4 per year) source: EuropePMC
JMIR cardio, Volume 6, Issue 1, 22 4 2022, Pages e29473 A Preoperative Virtual Reality App for Patients Scheduled for Cardiac Catheterization: Pre-Post Questionnaire Study Examining Feasibility, Usability, and Acceptability. Aardoom JJ, Hilt AD, Woudenberg T, Chavannes NH, Atsma DE
Background: Pre- and postoperative anxiety is a common phenomenon associated with negative postoperative outcomes. Symptoms of posttraumatic stress disorder, such as fear, nightmares, and sleep deprivation, are prevalent in approximately 30% to 50% of patients following discharge from intensive care units after cardiac surgery. Preliminary evidence suggests a promising role of virtual reality (VR) in preventing stress-related reactions using stress inoculation training. Such training enables cog... Abstract
Cited 1 times since 2022 (0.3 per year) source: EuropePMC
Frontiers in psychiatry, Volume 13, 22 4 2022, Pages 774251 Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies. Syrogiannouli L, Wildisen L, Meuwese C, Bauer DC, Cappola AR, Gussekloo J, den Elzen WPJ, Trompet S, Westendorp RGJ, Jukema JW, Ferrucci L, Ceresini G, Åsvold BO, Chaker L, Peeters RP, Imaizumi M, Ohishi W, Vaes B, Völzke H, Sgarbi JA, Walsh JP, Dullaart RPF, Bakker SJL, Iacoviello M, Rodondi N, Del Giovane C
Background: In non-randomized studies (NRSs) where a continuous outcome variable (e.g., depressive symptoms) is assessed at baseline and follow-up, it is common to observe imbalance of the baseline values between the treatment/exposure group and control group. This may bias the study and consequently a meta-analysis (MA) estimate. These estimates may differ across statistical methods used to deal with this issue. Analysis of individual participant data (IPD) allows standardization of methods acr... Abstract
Cited 1 times since 2022 (0.3 per year) source: EuropePMC
The American journal of cardiology, Volume 170, 21 3 2022, Pages 1-9 Prognostic Relevance of Right Ventricular Remodeling after ST-Segment Elevation Myocardial Infarction in Patients Treated With Primary Percutaneous Coronary Intervention. Chimed S, van der Bijl P, Lustosa RP, Hirasawa K, Yedidya I, Fortuni F, van der Velde E, Montero-Cabezas JM, Marsan NA, Gersh BJ, Delgado V, Bax JJ
ST-segment elevation myocardial infarction (STEMI) often leads to changes in right ventricular (RV) function and size over time. The prognostic implications of RV remodeling after STEMI, however, are unknown. RV remodeling in patients who underwent STEMI with primary percutaneous coronary intervention (PCI) was defined by RV end-systolic area (RV ESA) change at 6 months after STEMI compared with baseline. The optimal threshold of RV ESA change (≥40%) to define RV remodeling was derived from spli... Abstract
Cited 5 times since 2022 (1.5 per year) source: EuropePMC
Evolutionary human sciences, Volume 4, 21 3 2022, Pages e11 Four levers of reciprocity across human societies: concepts, analysis and predictions. Lehmann L, Powers ST, van Schaik CP
This paper surveys five human societal types - mobile foragers, horticulturalists, pre-state agriculturalists, state-based agriculturalists and liberal democracies - from the perspective of three core social problems faced by interacting individuals: coordination problems, social dilemmas and contest problems. We characterise the occurrence of these problems in the different societal types and enquire into the main force keeping societies together given the prevalence of these. To address this,... Abstract
Cited 4 times since 2022 (1.2 per year) source: EuropePMC
International journal of cardiology, Volume 355, 18 3 2022, Pages 65-71 Prognostic implications of staging cardiac remodeling in patients undergoing cardiac resynchronization therapy. Stassen J, Khidir M, Galloo X, Hirasawa K, Knuuti J, Marsan NA, Delgado V, van der Bijl P, Bax JJ
Background: Cardiac resynchronization therapy (CRT) candidates often present with significant mitral and tricuspid regurgitation, pulmonary hypertension and right ventricular dysfunction when referred for device implantation. This study investigated the prognostic value of a novel cardiac staging system, based on the extent of cardiac remodeling prior to implantation. Methods: Data were collected from an ongoing registry of CRT recipients. Patients were divided into 4 groups according to the ext... Abstract
Cited 7 times since 2022 (2.1 per year) source: EuropePMC
Heart rhythm, Volume 19, Issue 6, 18 3 2022, Pages 927-936 Impact of baseline left ventricular volume on left ventricular reverse remodeling after cardiac resynchronization therapy. Galloo X, Stassen J, Hirasawa K, Chimed S, Cosyns B, Ajmone Marsan N, Delgado V, van der Bijl P, Bax JJ
Background: Left ventricular (LV) dilatation may limit LV reverse remodeling after cardiac resynchronization therapy (CRT). Objective: The purpose of this study was to evaluate the impact of baseline LV volumes on LV reverse remodeling after CRT and whether this is associated with improved survival. Methods: Patients were stratified into quintiles according to baseline LV end-diastolic volume indexed for body surface area (LVEDVi). LV reverse remodeling was defined as ≥15% reduction in LV end-sy... Abstract
European heart journal. Case reports, Volume 6, Issue 3, 17 3 2022, Pages ytac087 Successful hybrid cardiac resynchronization therapy in a patient with failing systemic right ventricle and significant tricuspid regurgitation in transposition of the great arteries after atrial switch procedure according to Mustard. Nederend M, Zeppenfeld K, Jongbloed MRM, Egorova AD
Background: Patients with a systemic right ventricle (sRV) in the context of transposition of the great arteries (TGA) late after atrial switch are prone to heart failure. Complications like tricuspid valve regurgitation (TR) can further aggravate sRV dysfunction. Tricuspid valve regurgitation is usually secondary to annular dilatation and restriction. Criteria for cardiac resynchronization therapy (CRT) in this patient group are not well defined and should be considered on a case-by-case basis.... Abstract
Cited 3 times since 2022 (0.9 per year) source: EuropePMC
European heart journal. Case reports, Volume 6, Issue 2, 16 3 2022, Pages ytac067 Case report of the broad spectrum of late complications in an adult patient with univentricular physiology palliated by the Fontan circulation. Nederend M, Egorova AD, Vliegen HW, Roest AAW, Ruijter BN, Korteweg T, Ninaber MK, Zeppenfeld K, Hazekamp MG, Kiès P, Jongbloed MRM
Background: At the most severe end of the spectrum of congenital heart disease are patients with an univentricular physiology. They comprise a heterogeneous group of congenital heart malformations that have the common characteristic that the cardiac morphology is not equipped for sustaining a biventricular circulation. Case summary: Here, we present a case of an adult patient after Fontan palliation, illustrative of the complex clinical course and the broad spectrum of complications that can be... Abstract
Cited 14 times since 2022 (4.3 per year) source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 63, Issue 3, 16 3 2022, Pages 390-399 Editor's Choice - Post-operative Surveillance and Long Term Outcome after Endovascular Aortic Aneurysm Repair in Patients with an Initial Post-operative Computed Tomography Angiogram Without Abnormalities: the Multicentre Retrospective ODYSSEUS Study. Geraedts ACM, Mulay S, Vahl AC, Verhagen HJM, Wisselink W, de Mik SML, van Dieren S, Koelemay MJW, Balm R, ODYSSEUS study group
Objective: Lifelong imaging surveillance is recommended following endovascular aneurysm repair (EVAR). This study aimed to examine the association between adherence to post-operative surveillance and survival and secondary interventions in patients with an initial post-operative computed tomography angiogram (CTA) without abnormalities. Methods: All consecutive patients undergoing EVAR for intact abdominal aortic aneurysm (AAA) in 16 hospitals between 2007 and 2012 were identified retrospectivel... Abstract
Cited 142 times since 2022 (43.2 per year) source: EuropePMC
Nature communications, Volume 13, Issue 1, 16 3 2022, Pages 893 Effects of early-life antibiotics on the developing infant gut microbiome and resistome: a randomized trial. Reyman M, van Houten MA, Watson RL, Chu MLJN, Arp K, de Waal WJ, Schiering I, Plötz FB, Willems RJL, van Schaik W, Sanders EAM, Bogaert D
Broad-spectrum antibiotics for suspected early-onset neonatal sepsis (sEONS) may have pronounced effects on gut microbiome development and selection of antimicrobial resistance when administered in the first week of life, during the assembly phase of the neonatal microbiome. Here, 147 infants born at ≥36 weeks of gestational age, requiring broad-spectrum antibiotics for treatment of sEONS in their first week of life were randomized 1:1:1 to receive three commonly prescribed intravenous antibioti... Abstract
Cited 10 times since 2022 (3 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 9, 15 3 2022, Pages 708298 Abutting Left Atrial Appendage and Left Superior Pulmonary Vein Predicts Recurrence of Atrial Fibrillation After Point-by-Point Pulmonary Vein Isolation. Szegedi N, Simon J, Szilveszter B, Salló Z, Herczeg S, Száraz L, Kolossváry M, Orbán G, Széplaki G, Nagy KV, Mahdiui ME, Smit JM, Delgado V, Bax JJ, Maurovich-Horvat P, Merkely B, Gellér L
Introduction: The role of the spatial relationship between the left superior pulmonary vein (LSPV) and left atrial appendage (LAA) is unknown. We sought to evaluate whether an abutting LAA and LSPV play a role in AF recurrence after catheter ablation for paroxysmal AF. Methods: Consecutive patients, who underwent initial point-by-point radiofrequency catheter ablation for paroxysmal AF at the Heart and Vascular Center of Semmelweis University, Budapest, Hungary, between January of 2014 and Decem... Abstract
Cited 2 times since 2022 (0.6 per year) source: EuropePMC
Frontiers in physiology, Volume 12, 14 2 2022, Pages 741317 Long-Term Endurance Exercise Training Alters Repolarization in a New Rabbit Athlete's Heart Model. Kui P, Polyák A, Morvay N, Tiszlavicz L, Nagy N, Ördög B, Takács H, Leprán I, Farkas A, Papp JG, Jost N, Varró A, Baczkó I, Farkas AS
In the present study, the effect of long-term exercise training was investigated on myocardial morphological and functional remodeling and on proarrhythmic sensitivity in a rabbit athlete's heart model. New-Zealand white rabbits were trained during a 12-week long treadmill running protocol and compared with their sedentary controls. At the end of the training protocol, echocardiography, in vivo and in vitro ECG recordings, proarrhythmic sensitivity with dofetilide (nM) were performed in iso... Abstract