6324 results
Cited 114 times since 2006 (6.2 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 48, Issue 9, 17 3 2006, Pages 1832-1838
Non-invasive visualization of the cardiac venous system in coronary artery disease patients using 64-slice computed tomography.
Van de Veire NR, Schuijf JD, De Sutter J, Devos D, Bleeker GB, de Roos A, van der Wall EE, Schalij MJ, Bax JJ
Objectives: This study was designed to evaluate the value of 64-slice computed tomography (CT) to visualize the cardiac veins and evaluate the relation between variations in venous anatomy and history of infarction. Background: Cardiac resynchronization therapy (CRT) is an attractive treatment for selected heart failure patients. Knowledge of venous anatomy may help in identifying candidates for successful left ventricular lead implantation. Methods: The 64-slice CT of 100 individuals (age 61 +/...
Abstract
Cited 3 times since 2006 (0.2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 98, Issue 11, 16 3 2006, Pages 1515-1518
Impact of glomerular filtration rate on minor troponin T elevations for risk assessment in patients undergoing operation for abdominal aortic aneurysm or lower extremity arterial obstruction.
Feringa HH, Bax JJ, de Jonge R, Elhendy A, van Domburg RT, Dunkelgrun M, Schouten O, Karagiannis SE, Vidakovic R, Poldermans D
Debate surrounds the impact of renal function on the prognostic value of minor troponin T release in vascular surgery patients. The objective of this study was to assess the long-term prognostic value of minor degrees of troponin T release in patients who undergo major vascular surgery, especially those with concomitant renal dysfunction. Survivors of major noncardiac vascular surgery (n = 558) were preoperatively screened for cardiac risk factors and renal function. Serial troponin T was measur...
Abstract
Cited 209 times since 2006 (11.4 per year)
source: EuropePMC
Gastroenterology,
Volume 132, Issue 1, 12 2 2006, Pages 66-75; quiz 432-3
Once-daily, high-concentration MMX mesalamine in active ulcerative colitis.
Kamm MA, Sandborn WJ, Gassull M, Schreiber S, Jackowski L, Butler T, Lyne A, Stephenson D, Palmen M, Joseph RE
Background & aims: SPD476 (LIALDA in the US; MEZAVANT in the EU; otherwise known as MMX mesalamine; Shire Pharmaceuticals Inc., Wayne, PA, under license from Giuliani SpA, Milan, Italy) is a novel, once-daily, high-strength (1.2 g/tablet) formulation of mesalamine, utilizing MMX Multi Matrix System (MMX) technology designed to deliver the active drug throughout the colon. We performed a double-blind, multicenter study, comparing MMX mesalamine vs placebo for the treatment of active ulcerativ...
Abstract
Cited 41 times since 2006 (2.2 per year)
source: EuropePMC
The British journal of ophthalmology,
Volume 91, Issue 3, 11 2 2006, Pages 313-318
Accuracy of GDx VCC, HRT I, and clinical assessment of stereoscopic optic nerve head photographs for diagnosing glaucoma.
Reus NJ, de Graaf M, Lemij HG
Aims: To determine and compare the accuracy and reproducibility of GDx variable cornea compensation (VCC) scanning laser polarimetry (SLP) with VCC, Heidelberg retina tomograph (HRT) I confocal scanning laser ophthalmoscopy (CSLO), and clinical assessment of stereoscopic optic nerve head (ONH) photographs for diagnosing glaucoma. Methods: One eye each of 40 healthy subjects, 48 glaucoma patients, and six patients with ocular hypertension were measured with SLP-VCC and CSLO. Simultaneous stereosc...
Abstract
Cited 62 times since 2006 (3.4 per year)
source: EuropePMC
European heart journal,
Volume 28, Issue 15, 9 2 2006, Pages 1854-1861
Outcome of implantable cardioverter defibrillators in adults with congenital heart disease: a multi-centre study.
Yap SC, Roos-Hesselink JW, Hoendermis ES, Budts W, Vliegen HW, Mulder BJ, van Dijk AP, Schalij MJ, Drenthen W
Aims: To investigate outcome and complications of implantable cardioverter defibrillators (ICDs) in adults with congenital heart disease (CHD) and to identify predictors of (in-) appropriate shocks. Methods and results: Sixty-four CHD patients >/= 18 years at first ICD implantation [63% tetralogy of Fallot (TOF) and age at implantation 37 +/- 13 years] were identified using the Dutch adult CHD registry and a Belgian tertiary care centre database. Median follow-up duration was 3.7 years. Early...
Abstract
Circulation,
Volume 114, Issue 14, 1 1 2006, Pages e526; author reply e527
Letter by Schinkel et al regarding article, "Projected valve area at normal flow rate improves the assessment of stenosis severity in patients with low-flow, low-gradient aortic stenosis: the multicenter TOPAS (Truly or Pseudo-Severe Aortic Stenosis) study".
Schinkel AF, Bountioukos M, Poldermans D, Bax JJ
Abstract
Cited 55 times since 2006 (3 per year)
source: EuropePMC
Alimentary pharmacology & therapeutics,
Volume 24, Issue 7, 1 1 2006, Pages 1087-1097
Once daily MMX mesalazine for the treatment of mild-to-moderate ulcerative colitis: a phase II, dose-ranging study.
D'Haens G, Hommes D, Engels L, Baert F, van der Waaij L, Connor P, Ramage J, Dewit O, Palmen M, Stephenson D, Joseph R
Background: SPD476 (MMX mesalazine), is a novel, once daily, high-strength mesalazine formulation (1.2 g/tablet) that utilizes Multi Matrix System (MMX) technology to delay and extend delivery of the active drug throughout the colon. Aim: To assess the safety and efficacy of MMX mesalazine in patients with mild-to-moderately active ulcerative colitis, in a pilot, phase II, randomized, multicentre, double-blind, parallel-group, dose-ranging study (SPD476-202). Methods: Thirty-eight patients with...
Abstract
Cited 61 times since 2006 (3.3 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 47, Issue 10, 1 1 2006, Pages 1565-1570
Extent of viability to predict response to cardiac resynchronization therapy in ischemic heart failure patients.
Ypenburg C, Schalij MJ, Bleeker GB, Steendijk P, Boersma E, Dibbets-Schneider P, Stokkel MP, van der Wall EE, Bax JJ
Unlabelled: The response to cardiac resynchronization therapy (CRT) varies significantly among individuals. Preliminary data suggest that the presence of myocardial viability may be important for response to CRT. The aim of this study was to evaluate whether the extent of viability could predict response to CRT after 6 mo. Methods: Sixty-one consecutive patients with advanced heart failure, left ventricular ejection fraction < 35%, QRS duration > 120 ms, and chronic coronary artery disease...
Abstract
Cited 36 times since 2006 (2 per year)
source: EuropePMC
American heart journal,
Volume 152, Issue 4, 1 1 2006, Pages 684.e11-6
Sustained effect of autologous bone marrow mononuclear cell injection in patients with refractory angina pectoris and chronic myocardial ischemia: twelve-month follow-up results.
Beeres SL, Bax JJ, Dibbets-Schneider P, Stokkel MP, Fibbe WE, van der Wall EE, Schalij MJ, Atsma DE
Background: Cell therapy has recently been introduced to treat patients with refractory angina. Because most studies have only included short-term follow-up, the effects of cell therapy over a longer period are unknown. Methods: In 25 patients (mean age 64 +/- 10 years, 21 men) with refractory angina, a total of 84 +/- 29 x 10(6) bone marrow-derived mononuclear cells was injected intramyocardially in regions with ischemia on technetium-99m tetrofosmin single-photon emission computed tomography....
Abstract
Cited 6 times since 2006 (0.3 per year)
source: EuropePMC
American heart journal,
Volume 152, Issue 4, 1 1 2006, Pages 636-640
Implantable defibrillator early after primary percutaneous intervention for ST-elevation myocardial infarction: rationale and design of the Defibrillator After Primary Angioplasty (DAPA) trial.
Ottervanger JP, Ramdat Misier AR, Zijlstra F, Schalij MJ, Wever E, Jordaens LJ, Henriques JP, de Boer MJ, Robbe HW, Wellens HJ, DAPA Investigators
Background: It has been shown that an implantable cardioverter defibrillator (ICD) may be beneficial when added to optimal drug treatment in patients with reduced left ventricular function who survive a myocardial infarction (MI). However, it is not known whether patients with increased risk of death after primary percutaneous coronary intervention (PCI) for ST-elevation MI also have benefit of prophylactic ICD therapy to reduce sudden cardiac death. Methods and study design: The DAPA trial is d...
Abstract
Cited 21 times since 2006 (1.1 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 17, Issue 10, 1 1 2006, Pages 1086-1092
Fragmented, long-duration, low-amplitude electrograms characterize the origin of focal atrial tachycardia.
De Groot NM, Schalij MJ
Background: Focal atrial tachycardias (FAT) originate from areas with poor cell-to-cell coupling. Due to cellular uncoupling extracellular potentials become fractionated. The degree of fragmentation may be used to identify the site of origin of FAT prior to catheter ablation. We studied electrical fragmentation in relation to the distance to the site of earliest activity during FAT. Methods: Three-dimensional (3-D) electroanatomical activation/voltage maps obtained from patients (n = 15: 6 male,...
Abstract
Cited 1 times since 2006 (0.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 14, Issue 10, 1 1 2006, Pages 323-324
Genetic factors in arrhythmogenic right ventricular cardiomyopathy: need for a DNA bank!
van der Wall EE, Schalij MJ, van der Laarse A
Abstract
Cited 145 times since 2006 (7.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 48, Issue 8, 27 4 2006, Pages 1642-1648
Right ventricular pacing can induce ventricular dyssynchrony in patients with atrial fibrillation after atrioventricular node ablation.
Tops LF, Schalij MJ, Holman ER, van Erven L, van der Wall EE, Bax JJ
Objectives: This study was designed to assess the effects of long-term right ventricular (RV) pacing on left ventricular (LV) dyssynchrony, LV function, and heart failure symptoms. Background: Atrioventricular (AV) node ablation and subsequent long-term RV pacing is a well-established treatment option in patients with atrial fibrillation (AF). Methods: In 55 patients with drug-refractory AF, AV node ablation and implantation of a pacemaker was performed. At baseline and after a mean of 3.8 +/- 1...
Abstract
Cited 3 times since 2006 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 27, Issue 20, 26 4 2006, Pages 2378-2379
Selecting optimal non-invasive cardiac imaging stress test in intermediate-risk patients using cost effectiveness analysis.
Poldermans D, Bax JJ
Abstract
Cited 25 times since 2006 (1.4 per year)
source: EuropePMC
Journal of cell science,
Volume 119, Issue Pt 20, 26 4 2006, Pages 4247-4256
Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells.
Raz V, Carlotti F, Vermolen BJ, van der Poel E, Sloos WC, Knaän-Shanzer S, de Vries AA, Hoeben RC, Young IT, Tanke HJ, Garini Y, Dirks RW
Apoptosis is fundamental to the regulation of homeostasis of stem cells in vivo. Whereas the pathways underlying the molecular and biochemical details of nuclear breakdown that accompanies apoptosis have been elucidated, the precise nature of nuclear reorganization that precedes the demolition phase is not fully understood. Here, we expressed an inducible caspase-8 in human mesenchymal stem cells, and quantitatively followed the early changes in nuclear organization during apoptosis. We found th...
Abstract
Cited 105 times since 2006 (5.7 per year)
source: EuropePMC
Stem cells (Dayton, Ohio),
Volume 25, Issue 2, 21 3 2006, Pages 271-278
Epicardial cells of human adults can undergo an epithelial-to-mesenchymal transition and obtain characteristics of smooth muscle cells in vitro.
van Tuyn J, Atsma DE, Winter EM, van der Velde-van Dijke I, Pijnappels DA, Bax NA, Knaän-Shanzer S, Gittenberger-de Groot AC, Poelmann RE, van der Laarse A, van der Wall EE, Schalij MJ, de Vries AA
Myocardial and coronary development are both critically dependent on epicardial cells. During cardiomorphogenesis, a subset of epicardial cells undergoes an epithelial-to-mesenchymal transition (EMT) and invades the myocardium to differentiate into various cell types, including coronary smooth muscle cells and perivascular and cardiac interstitial fibroblasts. Our current knowledge of epicardial EMT and the ensuing epicardium-derived cells (EPDCs) comes primarily from studies of chick and mouse...
Abstract
Journal of the American College of Cardiology,
Volume 48, Issue 7, 12 2 2006, Pages 1472; author reply 1472-3
Risk stratification with electrocardiographic-gated dobutamine stress imaging.
Elhendy A, Schinkel AF, Bax JJ, Poldermans D
Abstract
Cited 16 times since 2006 (0.9 per year)
source: EuropePMC
Heart rhythm,
Volume 4, Issue 1, 9 2 2006, Pages 88-91
Incessant ventricular tachycardia in fulminant lymphocytic myocarditis: Evidence for origin in the Purkinje system and successful treatment with ablation.
Zeppenfeld K, Blom NA, Bootsma M, Schalij MJ
Abstract
Cited 27 times since 2006 (1.5 per year)
source: EuropePMC
Molecular and cellular biology,
Volume 26, Issue 20, 5 1 2006, Pages 7731-7746
Identification of new human origins of DNA replication by an origin-trapping assay.
Gerhardt J, Jafar S, Spindler MP, Ott E, Schepers A
Metazoan genomes contain thousands of replication origins, but only a limited number have been characterized so far. We developed a two-step origin-trapping assay in which human chromatin fragments associated with origin recognition complex (ORC) in vivo were first enriched by chromatin immunoprecipitation. In a second step, these fragments were screened for transient replication competence in a plasmid-based assay utilizing the Epstein-Barr virus latent origin oriP. oriP contains two elements,...
Abstract
Cited 16 times since 2006 (0.9 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 13, Issue 5, 1 1 2006, Pages 635-641
Do risk factors influence the diagnostic accuracy of noninvasive coronary angiography with multislice computed tomography?
Schuijf JD, Mollet NR, Cademartiri F, Jukema JW, Lamb HJ, de Roos A, van der Wall EE, de Feyter PJ, Bax JJ
Background: Multislice computed tomography (MSCT) is a relatively new noninvasive imaging modality in the evaluation of patients with suspected coronary artery disease (CAD). Whether diagnostic accuracy is influenced by gender or risk factors for CAD is currently unknown and was evaluated in this study. Methods and results: In 197 patients (171 men and 26 women; mean age, 60 +/- 11 years) 16-slice MSCT was performed and compared with invasive coronary angiography at 2 different centers (Leiden a...
Abstract
