8684 results
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Methods in molecular biology (Clifton, N.J.),
Volume 2458, 1 1 2022, Pages 215-229
Genome-Wide Mapping and Microscopy Visualization of Protein-DNA Interactions by pA-DamID.
van Schaik T, Manzo SG, van Steensel B
Several methods have been developed to map protein-DNA interactions genome-wide in the last decades. Protein A-DamID (pA-DamID) is a recent addition to this list with distinct advantages. pA-DamID relies on antibody-based targeting of the bacterial Dam enzyme, resulting in adenine methylation of DNA in contact with the protein of interest. This m6A can then be visualized by microscopy, or mapped genome-wide. The main advantages of pA-DamID are an easy and direct visualization of DNA that is in c...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
The Journal of the Acoustical Society of America,
Volume 151, Issue 1, 1 1 2022, Pages 500
Noise-robust text-dependent speaker identification using cochlear models.
Islam MA, Xu Y, Monk T, Afshar S, van Schaik A
One challenging issue in speaker identification (SID) is to achieve noise-robust performance. Humans can accurately identify speakers, even in noisy environments. We can leverage our knowledge of the function and anatomy of the human auditory pathway to design SID systems that achieve better noise-robust performance than conventional approaches. We propose a text-dependent SID system based on a real-time cochlear model called cascade of asymmetric resonators with fast-acting compression (CARFAC)...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
BJS open,
Volume 6, Issue 1, 1 1 2022, Pages zrab150
Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery.
STARSurg Collaborative and EuroSurg Collaborative
Background: Postoperative acute kidney injury (AKI) is a common complication of major gastrointestinal surgery with an impact on short- and long-term survival. No validated system for risk stratification exists for this patient group. This study aimed to validate externally a prognostic model for AKI after major gastrointestinal surgery in two multicentre cohort studies. Methods: The Outcomes After Kidney injury in Surgery (OAKS) prognostic model was developed to predict risk of AKI in the 7 day...
Abstract
Cited 6 times since 2022 (1.7 per year)
source: EuropePMC
European heart journal. Cardiovascular pharmacotherapy,
Volume 8, Issue 1, 1 1 2022, Pages 77-84
Medication in adults after atrial switch for transposition of the great arteries: clinical practice and recommendations.
Woudstra OI, Kuijpers JM, Jongbloed MRM, van Dijk APJ, Sieswerda GT, Vliegen HW, Egorova AD, Kiès P, Duijnhouwer AL, Robbers-Visser D, Konings TC, Zwinderman AH, Meijboom FJ, Mulder BJM, Bouma BJ
Aims: Heart failure is the main threat to long-term health in adults with transposition of the great arteries (TGA) corrected by an atrial switch operation (AtrSO). Current guidelines refrain from recommending heart failure medication in TGA-AtrSO, as there is insufficient data to support the hypothesis that it is beneficial. Medication is therefore prescribed based on personal judgements. We aimed to evaluate medication use in TGA-AtrSO patients and examine the association of use of renin-angio...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Pediatrics international : official journal of the Japan Pediatric Society,
Volume 64, Issue 1, 1 1 2022, Pages e14858
Early application of non-invasive ventilation for children with pulmonary edema after drowning.
Şık N, Şenol HB, Çağlar A, Yılmaz D, Duman M
Background: The present study aimed to assess the efficacy of non-invasive ventilation (NIV) on the clinical course, oxygenation, need for invasive mechanical ventilation (IMV), and outcomes for children with pulmonary edema after drowning. Methods: We conducted a retrospective chart review. Children who were referred to the pediatric emergency department due to drowning-related pulmonary edema and underwent NIV between May 2014 and October 2020 were included. Demographics, vital signs, clinical...
Abstract
Journal of chromatographic science,
Volume 60, Issue 1, 1 1 2022, Pages 96-103
Application of Tandem Dispersive Liquid-Liquid Microextraction as an Efficient Method for Preconcentration of Two Antidepressant Drugs in Real Samples Combined with High Performance Liquid Chromatography.
Arabkhani B, Goudarzi N, Bagherian G, Chamjangali MA
In the present work, tandem dispersive liquid-liquid microextraction (TDLLME) coupled with liquid chromatography was used for the determination of the two antidepressant drugs citalopram (CIT) and sertraline (SER) in complicated matrices. Indeed, the present approach was used to improve the suitability and appropriateness of the dispersive liquid-liquid microextraction (DLLME) method in complicated matrices. Firstly, 10 mL of the sample solution containing the two understudied drugs was extracte...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
Methods in molecular biology (Clifton, N.J.),
Volume 2478, 1 1 2022, Pages 677-700
Mechanics of Single Vimentin Intermediate Filaments Under Load.
Schepers AV, Kraxner J, Lorenz C, Köster S
The eukaryotic cytoskeleton consists of three different types of biopolymers - microtubules, actin filaments, and intermediate filaments - and provides cells with versatile mechanical properties, combining stability and flexibility. The unique molecular structure of intermediate filaments leads to high extensibility and stability under load. With high laser power dual optical tweezers, the mechanical properties of intermediate filaments may be investigated, while monitoring the extension with fl...
Abstract
Cited 4 times since 2022 (1.2 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 2, 1 1 2022, Pages 266-274
Associations between dyspnoea, coronary atherosclerosis, and cardiovascular outcomes: results from the long-term follow-up CONFIRM registry.
van Rosendael AR, Bax AM, van den Hoogen IJ, Smit JM, Al'Aref SJ, Achenbach S, Al-Mallah MH, Andreini D, Berman DS, Budoff MJ, Cademartiri F, Callister TQ, Chang HJ, Chinnaiyan K, Chow BJW, Cury RC, DeLago A, Feuchtner G, Hadamitzky M, Hausleiter J, Kaufmann PA, Kim YJ, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Raff GL, Rubinshtein R, Villines TC, Gransar H, Lu Y, Peña JM, Lin FY, Shaw LJ, Narula J, Min JK, Bax JJ
Aims: The relationship between dyspnoea, coronary artery disease (CAD), and major cardiovascular events (MACE) is poorly understood. This study evaluated (i) the association of dyspnoea with the severity of anatomical CAD by coronary computed tomography angiography (CCTA) and (ii) to which extent CAD explains MACE in patients with dyspnoea. Methods and results: From the international COronary CT Angiography EvaluatioN for Clinical Outcomes: An InteRnational Multicenter (CONFIRM) registry, 4425 p...
Abstract
Cited 4 times since 2021 (1.2 per year)
source: EuropePMC
Pediatric nephrology (Berlin, Germany),
Volume 37, Issue 8, 31 5 2022, Pages 1867-1875
Impact of coronavirus disease-2019 on pediatric nephrology practice and education: an ESPN survey.
Yazıcıoğlu B, Bakkaloğlu SA, European Society for Pediatric Nephrology
Background: Coronavirus disease-2019 (COVID-19) has been challenging for patients and medical staff. Radical changes have been needed to prevent disruptions in patient care and medical education. Methods: A web-based survey was sent to European Society for Pediatric Nephrology (ESPN) members via the ESPN mailing list to evaluate the effects of the COVID-19 pandemic on delivery of pediatric nephrology (PN) care and educational activities. There were ten questions with subheadings. Results: Sevent...
Abstract
Cited 9 times since 2021 (2.6 per year)
source: EuropePMC
Micromachines,
Volume 13, Issue 1, 29 5 2022, Pages 49
Rapid Prototyping of Organ-on-a-Chip Devices Using Maskless Photolithography.
Kasi DG, de Graaf MNS, Motreuil-Ragot PA, Frimat JMS, Ferrari MD, Sarro PM, Mastrangeli M, van den Maagdenberg AMJM, Mummery CL, Orlova VV
Organ-on-a-chip (OoC) and microfluidic devices are conventionally produced using microfabrication procedures that require cleanrooms, silicon wafers, and photomasks. The prototyping stage often requires multiple iterations of design steps. A simplified prototyping process could therefore offer major advantages. Here, we describe a rapid and cleanroom-free microfabrication method using maskless photolithography. The approach utilizes a commercial digital micromirror device (DMD)-based setup using...
Abstract
Cited 10 times since 2021 (2.9 per year)
source: EuropePMC
Annals of surgery,
Volume 276, Issue 1, 28 4 2022, Pages 38-45
Pelvic Floor Rehabilitation After Rectal Cancer Surgery: A Multicenter Randomized Clinical Trial (FORCE Trial).
van der Heijden JAG, Kalkdijk-Dijkstra AJ, Pierie JPEN, van Westreenen HL, Broens PMA, Klarenbeek BR, FORCE trial group
Objective: To investigate the effects of PFR after LAR compared to usual care without PFR. Summary of background data: Functional complaints, including fecal incontinence, often occur after LAR for rectal cancer. Controversy exists about the effectiveness of PFR in improving such postoperative functional outcomes. Methods: This was a multicenter, randomized controlled trial involving 17 Dutch centers. Patients after LAR for rectal cancer were randomly assigned (1:1) to usual care or PFR and stra...
Abstract
Cited 11 times since 2021 (3.2 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 35, Issue 5, 23 4 2021, Pages 486-494.e2
Left Atrial Deformation Imaging and Atrial Fibrillation in Patients with Rheumatic Mitral Stenosis.
Stassen J, Butcher SC, Namazi F, Ajmone Marsan N, Bax JJ, Delgado V
Background: Atrial fibrillation (AF) is a frequent complication of rheumatic mitral stenosis (MS) and is associated with worse outcomes. Prediction of new-onset AF by assessing left atrial (LA) mechanics with speckle-tracking echocardiography might be useful for risk stratification and guiding therapeutic strategies. Therefore, the aim of this study was to assess the association of LA reservoir strain (LASr) and strain rate (LASRr) with AF at follow-up in patients with rheumatic MS. Methods: Lef...
Abstract
Cited 2 times since 2021 (0.6 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 15, Issue 1, 23 4 2021, Pages e009886
Ultrasound-Guided Optogenetic Gene Delivery for Shock-Free Ventricular Rhythm Restoration.
Nyns ECA, Jin T, Bart CI, Bax WH, Zhang G, Poelma RH, de Vries AAF, Pijnappels DA
Abstract
Cited 47 times since 2021 (13.6 per year)
source: EuropePMC
Journal of advanced research,
Volume 40, 22 4 2021, Pages 1-15
The microbiota of the grapevine holobiont: A key component of plant health.
Bettenfeld P, Cadena I Canals J, Jacquens L, Fernandez O, Fontaine F, van Schaik E, Courty PE, Trouvelot S
Background: Grapevine is a woody, perennial plant of high economic importance worldwide. Like other plants, it lives in close association with large numbers of microorganisms. Bacteria, fungi and viruses are structured in communities, and each individual can be beneficial, neutral or harmful to the plant. In this sense, microorganisms can interact with each other and regulate plant functions (including immunity) and even provide new ones. Thus, the grapevine associated with its microbial communi...
Abstract
Cited 8 times since 2021 (2.3 per year)
source: EuropePMC
Seminars in musculoskeletal radiology,
Volume 25, Issue 6, 22 4 2021, Pages 735-744
Orthobiologics: Diagnosis and Treatment of Common Tendinopathies.
Van Schaik KD, Lee KS
Orthobiologics, including platelet-rich plasma, prolotherapy, and mesenchymal stem cells, are seeing increasing use in the treatment of osteoarthritis (OA), muscle injury, and tendinopathy. This article reviews the biology and applications of orthobiologics in tendons, muscles, and joints, and focuses on platelet-rich plasma (PRP). Clinical evidence-based literature related to the use of PRP in the treatment of rotator cuff injury, lateral epicondylosis, Achilles tendinopathy, plantar fasciitis,...
Abstract
Cited 86 times since 2021 (24.9 per year)
source: EuropePMC
Nature immunology,
Volume 23, Issue 1, 22 4 2021, Pages 23-32
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8<sup>+</sup> T cell responses following COVID-19.
Roukens AHE, Pothast CR, König M, Huisman W, Dalebout T, Tak T, Azimi S, Kruize Y, Hagedoorn RS, Zlei M, Staal FJT, de Bie FJ, van Dongen JJM, Arbous SM, Zhang JLH, Verheij M, Prins C, van der Does AM, Hiemstra PS, de Vries JJC, Janse JJ, Roestenberg M, Myeni SK, Kikkert M, Yazdanbakhsh M, Heemskerk MHM, Smits HH, Jochems SP, in collaboration with BEAT-COVID group, in collaboration with COVID-19 LUMC group
Systemic immune cell dynamics during coronavirus disease 2019 (COVID-19) are extensively documented, but these are less well studied in the (upper) respiratory tract, where severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replicates1-6. Here, we characterized nasal and systemic immune cells in individuals with COVID-19 who were hospitalized or convalescent and compared the immune cells to those seen in healthy donors. We observed increased nasal granulocytes, monocytes, CD11c+ natura...
Abstract
Cited 1 times since 2021 (0.3 per year)
source: EuropePMC
Acta chirurgica Belgica,
Volume 122, Issue 2, 22 4 2021, Pages 77-84
Peri-operative nutrition in cardiovascular surgery: current pitfalls and future directions.
Vinck EE, van Ierland KM, Rendón JC, Escobar JJ, Quintero Gómez A, Saldarriaga CI, van Brakel T, Klautz RJM, Cárdenas D
In the field of cardiovascular surgery, many areas are frequently evaluated to improve patient outcomes. Even though cardiac surgery has advanced significantly, peri-operative nutrition remains an area needing special attention and is under-considered in patient results. The three portions of cardiac surgical nutrition optimization are pre-operative, intra-operative and post-operative. All these, merit important clinical intervention which when done properly can significantly improve patient rec...
Abstract
Cited 3 times since 2021 (0.9 per year)
source: EuropePMC
Journal of orthopaedic surgery and research,
Volume 16, Issue 1, 20 3 2021, Pages 722
Does circumferential casting prevent fracture redisplacement in reduced distal radius fractures? A retrospective multicentre study.
Berger AC, Barvelink B, Reijman M, Gosens T, Kraan GA, De Vries MR, Verhofstad MHJ, Lansink KWW, Hannemann PFW, Colaris JW
Background: This study evaluates whether a circumferential cast compared to a plaster splint leads to less fracture redisplacement in reduced extra-articular distal radius fractures (DRFs). Methods: This retrospective multicentre study was performed in four hospitals (two teaching hospitals and two academic hospitals). Adult patients with a displaced extra-articular DRF, treated with closed reduction, were included. Patients were included from a 5-year period (January 2012-January 2017). Accordi...
Abstract
Cited 7 times since 2021 (2 per year)
source: EuropePMC
American heart journal,
Volume 245, 20 3 2021, Pages 117-125
Harmonization of the definition of sudden cardiac death in longitudinal cohorts of the European Sudden Cardiac Arrest network - towards Prevention, Education, and New Effective Treatments (ESCAPE-NET) consortium.
Warming PE, Ågesen FN, Lynge TH, Jabbari R, Smits RLA, van Valkengoed IGM, Welten SJGC, van der Heijden AA, Elders PJ, Blom MT, Jouven X, Schwartz PJ, Albert CM, Beulens JW, Rutters F, Tan HL, Empana JP, Tfelt-Hansen J, ESCAPE-NET Investigators
Background: The burden of sudden cardiac death (SCD) in the general population is substantial and SCD frequently occurs among people with few or no known risk factors for cardiac disease. Reported incidences of SCD vary due to differences in definitions and methodology between cohorts. This study aimed to develop a method for adjudicating SCD cases in research settings and to describe uniform case definitions of SCD in an international consortium harmonizing multiple longitudinal study cohorts....
Abstract
Cited 7 times since 2021 (2 per year)
source: EuropePMC
Insights into imaging,
Volume 12, Issue 1, 18 3 2021, Pages 186
The impact and challenges of implementing CTCA according to the 2019 ESC guidelines on chronic coronary syndromes: a survey and projection of CTCA services in the Netherlands.
van den Boogert TPW, Claessen BEPM, Boekholdt SM, Leiner T, Vliegenthart R, Schuiling SF, Timmer JR, Bekkers SCAM, Voskuil M, Siebelink HJ, van Es W, Lamb HJ, Prokop M, Damman P, Stoker J, Willems HC, Henriques JP, Planken RN
Background: The 2019 ESC-guidelines on chronic coronary syndromes (ESC-CCS) recommend computed tomographic coronary angiography (CTCA) or non-invasive functional imaging instead of exercise ECG as initial test to diagnose obstructive coronary artery disease. Since impact and challenges of these guidelines are unknown, we studied the current utilisation of CTCA-services, status of CTCA-protocols and modeled the expected impact of these guidelines in the Netherlands. Methods and results: A survey...
Abstract
