6254 results
Cited 36 times since 2006 (1.9 per year)
source: EuropePMC
Vascular pharmacology,
Volume 45, Issue 5, 22 4 2006, Pages 281-301
Murine models of myocardial and limb ischemia: diagnostic end-points and relevance to clinical problems.
Madeddu P, Emanueli C, Spillmann F, Meloni M, Bouby N, Richer C, Alhenc-Gelas F, Van Weel V, Eefting D, Quax PH, Hu Y, Xu Q, Hemdahl AL, van Golde J, Huijberts M, de Lussanet Q, Struijker Boudier H, Couffinhal T, Duplaa C, Chimenti S, Staszewsky L, Latini R, Baumans V, Levy BI
Ischemic disease represents the new epidemic worldwide. Animal models of ischemic disease are useful because they can help us to understand the underlying pathogenetic mechanisms and develop new therapies. The present review article summarizes the results of a consensus conference on the status and future development of experimentation in the field of cardiovascular medicine using murine models of peripheral and myocardial ischemia. The starting point was to recognize the limits of the approach,...
Abstract
Cited 131 times since 2006 (7.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 48, Issue 5, 17 3 2006, Pages 964-969
Should major vascular surgery be delayed because of preoperative cardiac testing in intermediate-risk patients receiving beta-blocker therapy with tight heart rate control?
Poldermans D, Bax JJ, Schouten O, Neskovic AN, Paelinck B, Rocci G, van Dortmont L, Durazzo AE, van de Ven LL, van Sambeek MR, Kertai MD, Boersma E, Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echo Study Group
Objectives: The purpose of this study was to assess the value of preoperative cardiac testing in intermediate-risk patients receiving beta-blocker therapy with tight heart rate (HR) control scheduled for major vascular surgery. Background: Treatment guidelines of the American College of Cardiology/American Heart Association recommend cardiac testing in these patients to identify subjects at increased risk. This policy delays surgery, even though test results might be redundant and beta-blockers...
Abstract
Cited 44 times since 2006 (2.4 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 93, Issue 2, 16 3 2006, Pages 226-231
Plasma N-terminal pro-B-type natriuretic peptide as long-term prognostic marker after major vascular surgery.
Feringa HH, Schouten O, Dunkelgrun M, Bax JJ, Boersma E, Elhendy A, de Jonge R, Karagiannis SE, Vidakovic R, Poldermans D
Objective: To assess the long-term prognostic value of plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) after major vascular surgery. Design: A single-centre prospective cohort study. Patients: 335 patients who underwent abdominal aortic aneurysm repair or lower extremity bypass surgery. Interventions: Prior to surgery, baseline NT-proBNP level was measured. Patients were also evaluated for cardiac risk factors according to the Revised Cardiac Risk Index. Dobutamine stress echocardio...
Abstract
Cited 32 times since 2006 (1.7 per year)
source: EuropePMC
Heart rhythm,
Volume 3, Issue 12, 10 2 2006, Pages 1397-1403
Right ventricular pacing and the risk of heart failure in implantable cardioverter-defibrillator patients.
Smit MD, Van Dessel PF, Nieuwland W, Wiesfeld AC, Tan ES, Anthonio RL, Van Erven L, Van Veldhuisen DJ, Van Gelder IC
Background: Right ventricular (RV) pacing in implantable cardioverter-defibrillator (ICD) patients may have detrimental effects on morbidity and mortality, in particular by inducing heart failure (HF). Objective: We investigated whether RV pacing increases the risk of HF in an asymptomatic ICD population. Methods: We evaluated all patients without symptomatic HF who received an ICD. The primary endpoint was the occurrence of HF, which was defined as new HF, hospitalization for HF, or death due t...
Abstract
Cited 5 times since 2006 (0.3 per year)
source: EuropePMC
Journal of pediatric gastroenterology and nutrition,
Volume 43, Issue 2, 1 1 2006, Pages 265-266
Rhamnose and rhamnitol in dual sugar permeability tests.
Malagon I, Onkenhout W, Klok M, van der Poel PF, Bovill JG, Hazekamp MG
Rhamnose is one of the sugars regularly used to conduct the dual sugar permeability test. For more than 30 years, it has been assumed that rhamnose is an inert sugar not metabolized by the human body and only fermented by some colonic bacteria into rhamnulose. While conducting an investigation on gut permeability in children undergoing cardiac surgery, increased concentrations of rhamnitol were found in the urine samples. The present report suggests that rhamnose is not an inert sugar and it is...
Abstract
Cited 3 times since 2006 (0.2 per year)
source: EuropePMC
Virus genes,
Volume 33, Issue 1, 1 1 2006, Pages 59-68
The intraleader AUG nucleotide sequence context is important for equine arteritis virus replication.
Archambault D, Kheyar A, de Vries AA, Rottier PJ
The 5(-terminal leader sequence of the equine arteritis virus (EAV) genome contains an open reading frame (ORF) with an AUG codon in a suboptimal context for initiation of protein synthesis. To investigate the significance of this intraleader ORF (ILO), an expression plasmid was generated carrying a DNA copy of the subgenomic mRNA7 behind a T7 promoter. Capped RNA transcribed from this construct was shown to direct, in an in vitro translation system, the synthesis of leader peptide as well as N...
Abstract
Cited 7 times since 2006 (0.4 per year)
source: EuropePMC
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists,
Volume 13, Issue 4, 1 1 2006, Pages 468-475
Roentgen stereophotogrammetric analysis: an accurate tool to assess stent-graft migration.
Koning OH, Oudegeest OR, Valstar ER, Garling EH, van der Linden E, Hinnen JW, Hamming JF, Vossepoel AM, van Bockel JH
Purpose: To evaluate in an in vitro model the feasibility and accuracy of Roentgen stereophotogrammetric analysis (RSA) versus computed tomography (CT) for the ability to detect stent-graft migration. Methods: An aortic model was constructed from a 22-mm-diameter Plexiglas tube with 6-mm polytetrafluoroethylene inlays to mimic the renal arteries. Six tantalum markers were placed in the wall of the aortic tube proximal to the renal arteries. Another 6 markers were added to a Gianturco stent, whic...
Abstract
Cited 6 times since 2006 (0.3 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 47, Issue 8, 1 1 2006, Pages 1307-1311
Nitrate administration increases blood flow in dysfunctional but viable myocardium, leading to improved assessment of myocardial viability: A PET study.
Slart RH, Agool A, van Veldhuisen DJ, Dierckx RA, Bax JJ
Unlabelled: SPECT with 99mTc-labeled agents is better able to detect viability after nitrate administration. Nitrates induce vasodilation and may increase blood flow to severely hypoperfused but viable myocardium, thereby enhancing tracer delivery and improving the detection of viability. Quantitative data on the changes in blood flow are lacking in SPECT but can be provided by PET. The aim of the present study was to use PET to evaluate whether nitrate administration increases blood flow to chr...
Abstract
Cited 28 times since 2006 (1.5 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 44, Issue 2, 1 1 2006, Pages 419-424
Statins for the prevention of perioperative cardiovascular complications in vascular surgery.
Schouten O, Bax JJ, Dunkelgrun M, Feringa HH, van Urk H, Poldermans D
Perioperative cardiovascular complications in vascular surgery remain a significant problem despite recent advancements in perioperative care. This clinical update summarizes the results of recent studies on the effectiveness and safety of perioperative statin use for the prevention of these perioperative cardiovascular complications. Five studies in patients undergoing major noncardiac vascular surgery and two studies in patients undergoing carotid endarterectomy are described. All studies repo...
Abstract
Cited 8 times since 2006 (0.4 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 47, Issue 8, 1 1 2006, Pages 1302-1306
Prognostic stratification of obese patients by stress 99mTc-tetrofosmin myocardial perfusion imaging.
Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Valkema R, Biagini E, Poldermans D
Unlabelled: Obesity is a major heath problem associated with increased cardiovascular mortality. There are currently no data to support a role for stress imaging techniques in the risk stratification of obese patients. The aim of this study was to assess the independent value of stress 99mTc-tetrofosmin SPECT in predicting mortality and hard cardiac events in obese patients. Methods: We studied 265 patients with a body mass index greater than 30 kg/m2 by exercise or dobutamine stress 99mTc-tetro...
Abstract
Cited 1 times since 2006 (0.1 per year)
source: EuropePMC
Coronary artery disease,
Volume 17, Issue 5, 1 1 2006, Pages 447-453
Hemodynamic responses and long-term follow-up results in patients using chronic beta 1-selective and nonselective beta-blockers during dobutamine stress echocardiography.
Feringa HH, Bax JJ, Elhendy A, van Domburg RT, Schouten O, Krenning B, Poldermans D
Objective: This study was undertaken to determine to what extent hemodynamic responses to dobutamine infusion between patients using concomitant beta1-selective or nonselective beta-blockers differ and whether this difference affects the long-term prognostic value of dobutamine stress echocardiography with respect to cardiac events. Design: Single center, observational study. Methods: A total of 1234 patients using chronic beta-blockers underwent dobutamine stress echocardiography and were prosp...
Abstract
Cited 3 times since 2006 (0.2 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 33, Issue 8, 1 1 2006, Pages 862-865
Will innervation imaging predict ventricular arrhythmias in ischaemic cardiomyopathy?
Henneman MM, Bengel FM, Bax JJ
Abstract
Cited 56 times since 2006 (3 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 17, Issue 8, 1 1 2006, Pages 899-901
Postero-lateral scar tissue resulting in non-response to cardiac resynchronization therapy.
Bleeker GB, Schalij MJ, Van Der Wall EE, Bax JJ
In large cardiac resynchronization therapy (CRT) trials, approximately 20-30% of patients did not respond to CRT. Recent studies indicated that left ventricular (LV) dyssynchrony is needed for response to CRT. However, the presence of LV dyssynchrony may not be the only determinant of response, because some patients with LV dyssynchrony do not benefit from CRT. In the current case report, we present a patient with ischemic cardiomyopathy, NYHA class III heart failure symptoms, and substantial LV...
Abstract
Journal of internal medicine,
Volume 260, Issue 2, 1 1 2006, Pages 183-185
Lipoprotein (a) and risk of cardiovascular disease in patients with metabolic syndrome in a population of familial hypercholesterolaemia.
Rana JS, Jansen AC, Zwinderman AH, van Aalst-Cohen ES, Jukema JW, Trip MD, Kastelein JJ
Abstract
Cited 20 times since 2006 (1.1 per year)
source: EuropePMC
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America,
Volume 43, Issue 5, 31 5 2006, Pages 616-623
Potential confounding in evaluating infection-control interventions in hospital settings: changing antibiotic prescription.
Nijssen S, Bootsma M, Bonten M
The colonization dynamics of antibiotic-resistant pathogens in hospital settings are complex, with multiple and continuously interacting variables (e.g., introduction of resistance, infection-control practices, antibiotic use). Quantification of these variables is indispensable in the evaluation of intervention studies, because these variables represent potential confounders. In this article, the complexity of colonization dynamics is described. Through a systematic review, we identified studies...
Abstract
Cited 45 times since 2006 (2.4 per year)
source: EuropePMC
Cardiovascular research,
Volume 72, Issue 2, 29 5 2006, Pages 282-291
Progressive increase in conduction velocity across human mesenchymal stem cells is mediated by enhanced electrical coupling.
Pijnappels DA, Schalij MJ, van Tuyn J, Ypey DL, de Vries AA, van der Wall EE, van der Laarse A, Atsma DE
Objective: The purpose of the study was to investigate the development of electrical transmission across human adult bone marrow-derived mesenchymal stem cells (hMSCs) during long-term co-incubation with cardiomyocytes (CMCs). Methods: Neonatal rat CMCs were cultured in multi-electrode array dishes. A conduction block was induced by creating a central acellular channel, yielding two asynchronously beating CMC fields. Enhanced green fluorescent protein (eGFP)-labeled hMSCs from ischemic heart dis...
Abstract
Cited 18 times since 2006 (1 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 33, Issue 12, 25 4 2006, Pages 1452-1460
Global and regional left ventricular function: a comparison between gated SPECT, 2D echocardiography and multi-slice computed tomography.
Henneman MM, Bax JJ, Schuijf JD, Jukema JW, Holman ER, Stokkel MP, Lamb HJ, de Roos A, van der Wall EE
Purpose: Global and regional left ventricular (LV) function are important indicators of the cardiac status in patients with coronary artery disease (CAD). Therapy and prognosis are to a large extent dependent on LV function. Multi-slice computed tomography (MSCT) has already earned its place as an imaging modality for non-invasive assessment of the coronary arteries, but since retrospective gating to the patient's ECG is performed, information on LV function can be derived. Methods: In 49 p...
Abstract
Cited 49 times since 2006 (2.6 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 48, Issue 4, 24 4 2006, Pages 754-760
The potential of myocardial perfusion scintigraphy for risk stratification of asymptomatic patients with type 2 diabetes.
Bax JJ, Bonow RO, Tschöpe D, Inzucchi SE, Barrett E, Global Dialogue Group for the Evaluation of Cardiovascular Risk in Patients With Diabetes
Patients with diabetes, in particular patients with type 2 diabetes, are at a 2- to 4-fold higher risk of cardiovascular mortality compared with their nondiabetic peers. Patients with diabetes are also more likely to have silent ischemia and less likely to survive a myocardial infarction than nondiabetic patients. Recent studies with electron beam computed tomography (EBCT) have shown that subclinical atherosclerosis is common in patients with diabetes, and studies with myocardial perfusion scin...
Abstract
Cited 31 times since 2006 (1.7 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 33, Issue 12, 18 3 2006, Pages 1442-1451
Accuracy of non-invasive techniques for diagnosis of coronary artery disease and prediction of cardiac events in patients with left bundle branch block: a meta-analysis.
Biagini E, Shaw LJ, Poldermans D, Schinkel AF, Rizzello V, Elhendy A, Rapezzi C, Bax JJ
Purpose: Non-invasive evaluation of coronary artery disease (CAD) in patients with left bundle branch block (LBBB) has limitations inherent to different tests, and the relative merits of these tests are unclear. This meta-analysis assessed the accuracy of the frequently used non-invasive techniques, including exercise electrocardiography (ECG), myocardial perfusion imaging (MPI) and stress echocardiography (SE), for detection of CAD and prediction of cardiac events in patients with LBBB. Methods...
Abstract
Cited 16 times since 2006 (0.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 48, Issue 3, 12 2 2006, Pages 464-470
Benefit of combined resynchronization and defibrillator therapy in heart failure patients with and without ventricular arrhythmias.
Ypenburg C, van Erven L, Bleeker GB, Bax JJ, Bootsma M, Wijffels MC, van der Wall EE, Schalij MJ
Objectives: We attempted to assess the efficacy of combined cardiac resynchronization therapy-implantable cardioverter-defibrillator (CRT-ICD) in heart failure patients with and without ventricular arrhythmias. Background: Because CRT and ICDs both lower all-cause mortality in patients with advanced heart failure, combination of both therapies in a single device is challenging. Methods: A total of 191 consecutive patients with advanced heart failure, left ventricular ejection fraction 120 ms rec...
Abstract
