7724 results
Cited 37 times since 2012 (2.9 per year)
source: EuropePMC
The American journal of cardiology,
Volume 110, Issue 7, 19 3 2012, Pages 961-967
Value of three-dimensional speckle-tracking longitudinal strain for predicting improvement of left ventricular function after acute myocardial infarction.
Abate E, Hoogslag GE, Antoni ML, Nucifora G, Delgado V, Holman ER, Schalij MJ, Bax JJ, Marsan NA
Identification of patients with reversible left ventricular (LV) dysfunction has important prognostic implications after acute myocardial infarction (AMI). This study aimed to determine the value of LV segmental and global longitudinal strains assessed with 3-dimensional (3D) speckle-tracking analysis in predicting improvement of LV function after AMI. One hundred fifty-three patients (80% men, 59 ± 11 years old) with AMI and treated with primary percutaneous coronary intervention underwent 3D e...
Abstract
Cited 10 times since 2012 (0.8 per year)
source: EuropePMC
Breast cancer research and treatment,
Volume 135, Issue 1, 16 3 2012, Pages 125-133
Expression of the BRCA1 complex member BRE predicts disease free survival in breast cancer.
Noordermeer SM, Wennemers M, Bergevoet SM, van der Heijden A, Tönnissen E, Sweep FC, Jansen JH, Span PN, van der Reijden BA
Breast cancer is one of the leading causes of cancer mortality in women. Recent advances in gene expression profiling have indicated that breast cancer is a heterogeneous disease and the current prognostication using clinico-pathological features is not sufficient to fully predict therapy response and disease outcome. In this retrospective study, we show that expression levels of BRE, which encodes a member of the BRCA1 DNA damage repair complex, predicted disease-free survival (DFS) in non-fami...
Abstract
Cited 25 times since 2012 (2 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 44, Issue 2, 15 3 2012, Pages 153-157
An association between chronic obstructive pulmonary disease and abdominal aortic aneurysm beyond smoking: results from a case-control study.
Meijer CA, Kokje VB, van Tongeren RB, Hamming JF, van Bockel JH, Möller GM, Lindeman JH
Objectives: It is currently unclear whether the parallels between abdominal aortic aneurysms (AAAs) and chronic obstructive pulmonary disease (COPD) are explained by common risk factors alone, such as cigarette smoking, or by a predetermined cause. Given the persistent controversy with regard to the association between AAA and COPD, we studied this association in depth. Methods: We conducted a case-control study comparing patients with a small AAA (maximum infrarenal diameter 35-50 mm, n = 221)...
Abstract
Cited 12 times since 2012 (0.9 per year)
source: EuropePMC
Geriatrics & gerontology international,
Volume 13, Issue 1, 11 2 2012, Pages 190-197
Do clinical characteristics and outcome in nonagenarians with a hip fracture differ from younger patients?
Vochteloo AJ, Borger van der Burg BL, Tuinebreijer WE, de Vries MR, Niggebrugge AH, Bloem RM, Maier AB, Nelissen RG, Pilot P
Aim: To compare clinical characteristics and outcome of nonagenarian hip fracture patients with younger patients aged 65-89 years. Methods: This was a cohort follow-up study of admissions for a hip fracture between 2005-2010 (mean follow up of 3.5 years) in two teaching hospitals in The Netherlands; 230 nonagenarians and 1014 patients aged 65-89 years were included. Clinical characteristics, adverse events, mobility and mortality were compared. Results: Nonagenarians were more likely to be femal...
Abstract
Cited 41 times since 2012 (3.2 per year)
source: EuropePMC
European heart journal,
Volume 33, Issue 24, 5 1 2012, Pages 3034-3045
From abstract to impact in cardiovascular research: factors predicting publication and citation.
Winnik S, Raptis DA, Walker JH, Hasun M, Speer T, Clavien PA, Komajda M, Bax JJ, Tendera M, Fox K, Van de Werf F, Mundow C, Lüscher TF, Ruschitzka F, Matter CM
Aims: Through a 4-year follow-up of the abstracts submitted to the European Society of Cardiology Congress in 2006, we aimed at identifying factors predicting high-quality research, appraising the quality of the peer review and editorial processes, and thereby revealing potential ways to improve future research, peer review, and editorial work. METHODS AND RESULTS All abstracts submitted in 2006 were assessed for acceptance, presentation format, and average reviewer rating. Accepted and rejected...
Abstract
Cited 26 times since 2012 (2 per year)
source: EuropePMC
Differentiation; research in biological diversity,
Volume 84, Issue 1, 3 1 2012, Pages 131-148
Normal and abnormal development of the cardiac conduction system; implications for conduction and rhythm disorders in the child and adult.
Jongbloed MR, Vicente Steijn R, Hahurij ND, Kelder TP, Schalij MJ, Gittenberger-de Groot AC, Blom NA
The cardiac conduction system is a specialized network that initiates and closely coordinates the heart beat. Cardiac conduction system development is intricately related to the development and maturation of the embryonic heart towards its four-chambered form, as is indicated by the fact that disturbed development of cardiac structures is often accompanied by a disturbed formation of the CCS. Electrophysiological studies have shown that selected conduction disturbances and cardiac arrhythmias do...
Abstract
Cited 17 times since 2012 (1.3 per year)
source: EuropePMC
Stem cells (Dayton, Ohio),
Volume 30, Issue 6, 1 1 2012, Pages 1236-1245
Gap junctional coupling with cardiomyocytes is necessary but not sufficient for cardiomyogenic differentiation of cocultured human mesenchymal stem cells.
Ramkisoensing AA, Pijnappels DA, Swildens J, Goumans MJ, Fibbe WE, Schalij MJ, de Vries AA, Atsma DE
Gap junctional coupling is important for functional integration of transplanted cells with host myocardium. However, the role of gap junctions in cardiomyogenic differentiation of transplanted cells has not been directly investigated. The objective of this work is to study the role of connexin43 (Cx43) in cardiomyogenic differentiation of human mesenchymal stem cells (hMSCs). Knockdown of Cx43 gene expression (Cx43↓) was established in naturally Cx43-rich fetal amniotic membrane (AM) hMSCs, whil...
Abstract
Cited 254 times since 2012 (19.9 per year)
source: EuropePMC
JAMA,
Volume 307, Issue 23, 1 1 2012, Pages 2499-2506
Lipid-related markers and cardiovascular disease prediction.
Emerging Risk Factors Collaboration, Di Angelantonio E, Gao P, Pennells L, Kaptoge S, Caslake M, Thompson A, Butterworth AS, Sarwar N, Wormser D, Saleheen D, Ballantyne CM, Psaty BM, Sundström J, Ridker PM, Nagel D, Gillum RF, Ford I, Ducimetiere P, Kiechl S, Koenig W, Dullaart RP, Assmann G, D'Agostino RB, Dagenais GR, Cooper JA, Kromhout D, Onat A, Tipping RW, Gómez-de-la-Cámara A, Rosengren A, Sutherland SE, Gallacher J, Fowkes FG, Casiglia E, Hofman A, Salomaa V, Barrett-Connor E, Clarke R, Brunner E, Jukema JW, Simons LA, Sandhu M, Wareham NJ, Khaw KT, Kauhanen J, Salonen JT, Howard WJ, Nordestgaard BG, Wood AM, Thompson SG, Boekholdt SM, Sattar N, Packard C, Gudnason V, Danesh J
Context: The value of assessing various emerging lipid-related markers for prediction of first cardiovascular events is debated. Objective: To determine whether adding information on apolipoprotein B and apolipoprotein A-I, lipoprotein(a), or lipoprotein-associated phospholipase A2 to total cholesterol and high-density lipoprotein cholesterol (HDL-C) improves cardiovascular disease (CVD) risk prediction. Design, setting, and participants: Individual records were available for 165,544 participant...
Abstract
Cited 23 times since 2012 (1.8 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 20, Issue 6, 1 1 2012, Pages 254-259
Acute myocardial infarction system of care in the third world.
Dharma S, Juzar DA, Firdaus I, Soerianata S, Wardeh AJ, Jukema JW
Background: We studied the characteristics of ST-elevation myocardial infarction (STEMI) patients from a local acute coronary syndrome (ACS) registry in order to find and build an appropriate acute myocardial infarction (AMI) system of care in Jakarta, Indonesia. Methods: Data were collected from the Jakarta Acute Coronary Syndrome (JAC) registry 2008-2009, which contained 2103 ACS patients, including 654 acute STEMI patients admitted to the National Cardiovascular Center Harapan Kita, Jakarta,...
Abstract
Cited 31 times since 2012 (2.4 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 98, Issue 11, 1 1 2012, Pages 872-877
Clinical prediction model for death prior to appropriate therapy in primary prevention implantable cardioverter defibrillator patients with ischaemic heart disease: the FADES risk score.
van Rees JB, Borleffs CJ, van Welsenes GH, van der Velde ET, Bax JJ, van Erven L, Putter H, van der Bom JG, Schalij MJ
Objectives: To construct a risk score out of baseline variables to estimate the risk of death without prior implantable cardioverter defibrillator (ICD) in primary prevention ICD patients with ischaemic heart disease. Design: Retrospective cohort study. Setting: Tertiary care facility in The Netherlands. Patients: All patients with ischaemic heart disease who received an ICD for primary prevention of sudden cardiac death at the Leiden University Medical Center, Leiden, The Netherlands in the per...
Abstract
Cited 42 times since 2012 (3.3 per year)
source: EuropePMC
Vaccine,
Volume 30, Issue 29, 1 1 2012, Pages 4369-4376
A review of influenza haemagglutinin receptor binding as it relates to pandemic properties.
Wilks S, de Graaf M, Smith DJ, Burke DF
Haemagglutinin is a determinant of many viral properties, and successful adaptation to a human-like form is thought to be an important step toward pandemic influenza emergence. The availability of structurally distinct sialic acid linked receptors in the sites of human and avian influenza infection are generally held to account for the differences observed, but the relevance of other selection pressures has not been elucidated. There is evidence for genetic and structural constraints of haemaggl...
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
Vascular,
Volume 20, Issue 4, 1 1 2012, Pages 203-209
Influence of aneurysm wall stiffness and the presence of intraluminal thrombus on the wall movement of an aneurysm - an in vitro study.
Bosman WM, Hinnen JW, Kopp WH, van der Steenhoven TJ, Kaptein BL, Koning OH, Hamming JF
The purpose of this in vitro study was to investigate the influence of aneurysm wall stiffness and of the presence of intraluminal thrombus (ILT) on aneurysm wall movement. Three latex aneurysms were used with different wall stiffness. The aneurysms, equipped with 20 tantalum markers, were attached to an in vitro circulation model. Fluoroscopic roentgenographic stereo photogrammetric analysis was used to measure marker movement during six cardiac cycles at three different systemic pressures. To...
Abstract
Cited 4 times since 2012 (0.3 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 20, Issue 6, 1 1 2012, Pages 251
Durrer prizes 2011.
van der Wall EE, Schalij MJ
Abstract
Cited 21 times since 2012 (1.6 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 5, 30 5 2012, Pages e38240
Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy.
Shiffman D, Trompet S, Louie JZ, Rowland CM, Catanese JJ, Iakoubova OA, Kirchgessner TG, Westendorp RG, de Craen AJ, Slagboom PE, Buckley BM, Stott DJ, Sattar N, Devlin JJ, Packard CJ, Ford I, Sacks FM, Jukema JW
Statin therapy reduces the risk of coronary heart disease (CHD), however, the person-to-person variability in response to statin therapy is not well understood. We have investigated the effect of genetic variation on the reduction of CHD events by pravastatin. First, we conducted a genome-wide association study of 682 CHD cases from the Cholesterol and Recurrent Events (CARE) trial and 383 CHD cases from the West of Scotland Coronary Prevention Study (WOSCOPS), two randomized, placebo-controlled...
Abstract
Cited 5 times since 2012 (0.4 per year)
source: EuropePMC
International wound journal,
Volume 10, Issue 3, 28 4 2012, Pages 348-350
Acute mediastinal bleeding during vacuum-assisted closure.
Vos RJ, Yilmaz A, Sonker U, Kloppenburg GT
Vacuum-assisted closure is commonly used to treat post-sternotomy mediastinitis. Several studies show improved outcome using vacuum-assisted therapy; however, risks using negative pressure should not be underestimated. We describe two cases of acute mediastinal bleeding during vacuum treatment for post-sternotomy mediastinitis and discuss preventative measurements.
Abstract
Cited 20 times since 2012 (1.6 per year)
source: EuropePMC
Resuscitation,
Volume 83, Issue 12, 24 4 2012, Pages 1503-1510
Left ventricular diastolic dysfunction during acute myocardial infarction: effect of mild hypothermia.
Schwarzl M, Huber S, Maechler H, Steendijk P, Seiler S, Truschnig-Wilders M, Nestelberger T, Pieske BM, Post H
Background: Mild hypothermia (MH) decreases infarct size and mortality in experimental reperfused myocardial infarction, but may potentiate ischaemia-induced left ventricular (LV) diastolic dysfunction. Methods: In anaesthetized pigs (70 ± 2 kg), polystyrol microspheres (45 μm) were infused repeatedly into the left circumflex artery until cardiac power output decreased >40%. Then, pigs were assigned to normothermia (NT, 38.0°C, n=8) or MH (33.0°C, n=8, intravascular cooling) and followed for...
Abstract
Cited 23 times since 2012 (1.8 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 32, Issue 8, 24 4 2012, Pages e72-80
Blocking toll-like receptors 7 and 9 reduces postinterventional remodeling via reduced macrophage activation, foam cell formation, and migration.
Karper JC, Ewing MM, Habets KL, de Vries MR, Peters EA, van Oeveren-Rietdijk AM, de Boer HC, Hamming JF, Kuiper J, Kandimalla ER, La Monica N, Jukema JW, Quax PH
Objective: The role of toll-like receptors (TLRs) in vascular remodeling is well established. However, the involvement of the endosomal TLRs is unknown. Here, we study the effect of combined blocking of TLR7 and TLR9 on postinterventional remodeling and accelerated atherosclerosis. Methods and results: In hypercholesterolemic apolipoprotein E*3-Leiden mice, femoral artery cuff placement led to strong increase of TLR7 and TLR9 presence demonstrated by immunohistochemistry. Blocking TLR7/9 with a...
Abstract
Cited 23 times since 2012 (1.8 per year)
source: EuropePMC
Diabetes & vascular disease research,
Volume 10, Issue 2, 23 4 2012, Pages 123-134
Non-invasive assessment of microcirculation by sidestream dark field imaging as a marker of coronary artery disease in diabetes.
Djaberi R, Schuijf JD, de Koning EJ, Wijewickrama DC, Pereira AM, Smit JW, Kroft LJ, Roos Ad, Bax JJ, Rabelink TJ, Jukema JW
Purpose: In diabetes, generalised microvascular disease and coronary artery disease (CAD) are likely to occur in parallel. We used a sidestream dark field (SDF) handheld imaging device to determine the relation between the labial microcirculation parameters and CAD in asymptomatic patients with diabetes. Methods: SDF imaging was validated for assessment of labial capillary density and tortuosity. Thereafter, mean labial capillary density and tortuosity were evaluated and compared in non-diabetic...
Abstract
Cited 571 times since 2012 (44.6 per year)
source: EuropePMC
Nature genetics,
Volume 44, Issue 6, 13 2 2012, Pages 659-669
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V, Lahti J, Lecoeur C, Liu Y, Martinez-Larrad MT, Montasser ME, Navarro P, Perry JR, Rasmussen-Torvik LJ, Salo P, Sattar N, Shungin D, Strawbridge RJ, Tanaka T, van Duijn CM, An P, de Andrade M, Andrews JS, Aspelund T, Atalay M, Aulchenko Y, Balkau B, Bandinelli S, Beckmann JS, Beilby JP, Bellis C, Bergman RN, Blangero J, Boban M, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Borecki IB, Böttcher Y, Bouchard C, Brunner E, Budimir D, Campbell H, Carlson O, Chines PS, Clarke R, Collins FS, Corbatón-Anchuelo A, Couper D, de Faire U, Dedoussis GV, Deloukas P, Dimitriou M, Egan JM, Eiriksdottir G, Erdos MR, Eriksson JG, Eury E, Ferrucci L, Ford I, Forouhi NG, Fox CS, Franzosi MG, Franks PW, Frayling TM, Froguel P, Galan P, de Geus E, Gigante B, Glazer NL, Goel A, Groop L, Gudnason V, Hallmans G,
Recent genome-wide association studies have described many loci implicated in type 2 diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the understanding of the genetic basis of insulin resistance. We hypothesized that genes implicated in insulin resistance pathways might be uncovered by accounting for differences in body mass index (BMI) and potential interactions between BMI and genetic variants. We applied a joint meta-analysis approach to test associations w...
Abstract
Cited 11 times since 2012 (0.9 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 29, Issue 1, 11 2 2012, Pages 221-228
Non-invasive computed tomography coronary angiography as a gatekeeper for invasive coronary angiography.
de Graaf FR, van Velzen JE, de Boer SM, van Werkhoven JM, Kroft LJ, de Roos A, Sieders A, de Grooth GJ, Jukema JW, Schuijf JD, Bax JJ, Schalij MJ, van der Wall EE
To determine the rate of subsequent invasive coronary angiography (ICA) and revascularization in relation to computed tomography coronary angiography (CTA) results. In addition, independent determinants of subsequent ICA and revascularization were evaluated. CTA studies were performed using a 64-row (n = 413) or 320-row (n = 224) multidetector scanner. The presence and severity of CAD were determined on CTA. Following CTA, patients were followed up for 1 year for the occurrence of ICA and revasc...
Abstract
