6143 results
Cited 1859 times since 2011 (137 per year)
source: EuropePMC
European heart journal,
Volume 32, Issue 23, 26 4 2011, Pages 2999-3054
ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC).
Hamm CW, Bassand JP, Agewall S, Bax J, Boersma E, Bueno H, Caso P, Dudek D, Gielen S, Huber K, Ohman M, Petrie MC, Sonntag F, Uva MS, Storey RF, Wijns W, Zahger D, ESC Committee for Practice Guidelines
Abstract
Cited 13 times since 2011 (1 per year)
source: EuropePMC
European journal of heart failure,
Volume 13, Issue 10, 25 4 2011, Pages 1133-1139
The effect of cardiac resynchronization therapy on left ventricular diastolic function assessed with speckle-tracking echocardiography.
Shanks M, Antoni ML, Hoke U, Bertini M, Ng AC, Auger D, Marsan NA, van Erven L, Holman ER, Schalij MJ, Bax JJ, Delgado V
Aims: Changes in left ventricular (LV) diastolic function after cardiac resynchronization therapy (CRT) in relation to LV reverse remodelling and heart failure aetiology have not been extensively characterized. The aims of the study were to evaluate changes in LV diastolic function with speckle-tracking echocardiography in relation to: (i) cardiac resynchronization therapy response (LV remodelling) and (ii) heart failure aetiology. Methods and results: A total of 192 heart failure patients under...
Abstract
Cited 14 times since 2011 (1 per year)
source: EuropePMC
BMC musculoskeletal disorders,
Volume 12, 24 4 2011, Pages 196
Displaced midshaft fractures of the clavicle: non-operative treatment versus plate fixation (Sleutel-TRIAL). A multicentre randomised controlled trial.
Stegeman SA, de Jong M, Sier CF, Krijnen P, Duijff JW, van Thiel TP, de Rijcke PA, Soesman NM, Hagenaars T, Boekhoudt FD, de Vries MR, Roukema GR, Tanka AF, van den Bremer J, van der Meulen HG, Bronkhorst MW, van Dijkman BA, van Zutphen SW, Vos DI, Schep NW, Eversdijk MG, van Olden GD, van den Brand JG, Hillen RJ, Frölke JP, Schipper IB
Background: The traditional view that the vast majority of midshaft clavicular fractures heal with good functional outcomes following non-operative treatment may be no longer valid for all midshaft clavicular fractures. Recent studies have presented a relatively high incidence of non-union and identified speciic limitations of the shoulder function in subgroups of patients with these injuries. Aim: A prospective, multicentre randomised controlled trial (RCT) will be conducted in 21 hospitals in...
Abstract
Cited 46 times since 2011 (3.4 per year)
source: EuropePMC
European heart journal,
Volume 33, Issue 1, 22 4 2011, Pages 96-102
Relationship between discharge heart rate and mortality in patients after acute myocardial infarction treated with primary percutaneous coronary intervention.
Antoni ML, Boden H, Delgado V, Boersma E, Fox K, Schalij MJ, Bax JJ
Aims: In patients with coronary artery disease, the prognostic value of heart rate has been mainly evaluated in patients with left ventricular dysfunction. Patients with ST-segment elevation acute myocardial infarction (STEMI) are currently treated with primary percutaneous coronary intervention (PCI) and in this contemporary population of patients, the relationship between heart rate and mortality during a follow-up >1 year has not been investigated. Methods and results: The population compr...
Abstract
Cited 15 times since 2011 (1.1 per year)
source: EuropePMC
BMC geriatrics,
Volume 11, 21 3 2011, Pages 48
[Cost] effectiveness of withdrawal of fall-risk increasing drugs versus conservative treatment in older fallers: design of a multicenter randomized controlled trial (IMPROveFALL-study).
Hartholt KA, Boyé ND, Van der Velde N, Van Lieshout EM, Polinder S, De Vries OJ, Kerver AJ, Ziere G, Bruijninckx MM, De Vries MR, Mattace-Raso FU, Uitterlinden AG, Van Beeck EF, Lips P, Patka P, Van der Cammen TJ
Background: Fall incidents represent an increasing public health problem in aging societies worldwide. A major risk factor for falls is the use of fall-risk increasing drugs. The primary aim of the study is to compare the effect of a structured medication assessment including the withdrawal of fall-risk increasing drugs on the number of new falls versus 'care as usual' in older adults presenting at the Emergency Department after a fall. Methods/design: A prospective, multi-center, rand...
Abstract
Cited 54 times since 2011 (4 per year)
source: EuropePMC
Cardiovascular research,
Volume 92, Issue 3, 19 3 2011, Pages 449-455
MicroRNA-126 modulates endothelial SDF-1 expression and mobilization of Sca-1(+)/Lin(-) progenitor cells in ischaemia.
van Solingen C, de Boer HC, Bijkerk R, Monge M, van Oeveren-Rietdijk AM, Seghers L, de Vries MR, van der Veer EP, Quax PH, Rabelink TJ, van Zonneveld AJ
Aims: MicroRNA-126 (miR-126), which is enriched in endothelial cells, plays a role in angiogenesis. Based on the seed sequence, miR-126 can also be predicted to regulate vasculogenesis by modulating the endothelial expression of stromal cell-derived factor-1 (SDF-1). Methods and results: Using miR-reporter constructs, we first validated that miR-126 inhibits SDF-1 expression in endothelial cells in vitro. Next, we investigated the potential relevance of this observation with respect to the mobil...
Abstract
Cited 8 times since 2011 (0.6 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 38, Issue 11, 18 3 2011, Pages 2050-2057
Relationship between vascular stiffness and stress myocardial perfusion imaging in asymptomatic patients with diabetes.
Roos CJ, Djaberi R, Schuijf JD, de Koning EJ, Rabelink TJ, Smit JW, Pereira AM, Al Younis I, van der Hiel B, Scholte AJ, Bax JJ, Jukema JW
Purpose: Vascular stiffness may potentially be used as a screening tool to identify asymptomatic patients with diabetes with abnormal myocardial perfusion. The purpose of this study was therefore to determine the association between vascular stiffness, measured in term of pulse wave velocity (PWV) and augmentation index (AIx), and abnormal myocardial perfusion imaging (MPI) in asymptomatic patients with diabetes. Methods: Prospectively, 160 asymptomatic patients with diabetes (mean age 51 years,...
Abstract
Cited 19 times since 2011 (1.4 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 38, Issue 11, 18 3 2011, Pages 2031-2039
Left ventricular diastolic dyssynchrony assessed with phase analysis of gated myocardial perfusion SPECT: a comparison with tissue Doppler imaging.
Boogers MJ, Chen J, Veltman CE, van Bommel RJ, Mooyaart EA, Al Younis I, van der Hiel B, Dibbets-Schneider P, van der Wall EE, Schalij MJ, Garcia EV, Bax JJ, Delgado V
Purpose: The aim of the current study was to evaluate the feasibility of phase analysis on gated myocardial perfusion SPECT (GMPS) for the assessment of left ventricular (LV) diastolic dyssynchrony in a head-to-head comparison with tissue Doppler imaging (TDI). Methods: The population consisted of patients with end-stage heart failure of New York Heart Association functional class III or IV with a reduced LV ejection fraction of ≤ 35%. LV diastolic dyssynchrony was calculated using TDI as the ma...
Abstract
European heart journal,
Volume 33, Issue 3, 17 3 2011, Pages 290-291
Will the interplay between genetic markers for risk factors for a disease and the disease itself bring genetics closer to clinical practice? Great expectations.
Trompet S, Jukema JW
Abstract
Cited 172 times since 2011 (12.6 per year)
source: Scopus
The American journal of cardiology,
Volume 108, Issue 10, 17 3 2011, Pages 1470-1477
Location and severity of aortic valve calcium and implications for aortic regurgitation after transcatheter aortic valve implantation.
Ewe SH, Ng AC, Schuijf JD, van der Kley F, Colli A, Palmen M, de Weger A, Marsan NA, Holman ER, de Roos A, Schalij MJ, Bax JJ, Delgado V
Location of aortic valve calcium (AVC) can be better visualized on contrast-enhanced multidetector row computed tomography. The present evaluation examined whether AVC severity and its location could influence paravalvular aortic regurgitation (AR) after transcatheter aortic valve implantation. A total of 79 patients (age 80 ± 7 years, 49% men) with preprocedural multidetector row computed tomography were included. Volumetric AVC quantification and its location were assessed. Transesophageal ech...
Abstract
Cited 5 times since 2011 (0.4 per year)
source: EuropePMC
European journal of heart failure,
Volume 13, Issue 11, 16 3 2011, Pages 1202-1210
Myocardial collagen turnover after surgical ventricular restoration in heart failure patients.
ten Brinke EA, Witkowski TG, Delgado V, Klein P, Klok M, Marsan NA, Klautz RJ, van der Wall EE, Bax JJ, van der Laarse A, Steendijk P
Aims: Surgical ventricular restoration (SVR) aims to normalize left ventricular (LV) volume and shape in patients with ischaemic cardiomyopathy and anterior wall scar. The chronic effects on LV function may depend on alterations in myocardial collagen metabolism. The present study evaluated myocardial collagen synthesis and degradation rates at baseline and at 6 months follow-up after SVR. We hypothesize that the chronic effects of SVR on LV function and clinical outcome depend on alterations in...
Abstract
Cited 128 times since 2011 (9.4 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 4, Issue 5, 13 2 2011, Pages 653-659
Epicardial ablation for ventricular tachycardia: a European multicenter study.
Della Bella P, Brugada J, Zeppenfeld K, Merino J, Neuzil P, Maury P, Maccabelli G, Vergara P, Baratto F, Berruezo A, Wijnmaalen AP
Background: The purpose of this study was to describe the epicardial percutaneous ablation experience of 6 European high-volume ventricular tachycardia (VT) ablation centers. Methods and results: Data from 218 patients with coronary artery disease (CAD, n=85 [39.0%]), idiopathic dilated of patients with idiopathic VT cardiomyopathy (IDCM, n=67 [30.7%]), arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARCD/C, n=13 [6%]), hypertrophic cardiomyopathy (HCM, n=5 [2.3%]), and absence of str...
Abstract
Cited 21 times since 2011 (1.5 per year)
source: EuropePMC
Inflammatory bowel diseases,
Volume 18, Issue 6, 11 2 2011, Pages 1026-1033
Strategies in maintenance for patients receiving long-term therapy (SIMPLE): a study of MMX mesalamine for the long-term maintenance of quiescent ulcerative colitis.
Kane S, Katz S, Jamal MM, Safdi M, Dolin B, Solomon D, Palmen M, Barrett K
Background: This was a phase IV, multicenter, open-label, 12-14-month study to assess clinical recurrence in patients with ulcerative colitis (UC) who received maintenance treatment with MMX Multi Matrix System (MMX) mesalamine. A secondary outcome was the relationship between long-term efficacy and adherence. Methods: Patients with quiescent UC (no rectal bleeding; 0-1 bowel movements more than normal per day) were enrolled directly into a 12-month maintenance phase of the study during which th...
Abstract
Cited 27 times since 2011 (2 per year)
source: EuropePMC
BMC geriatrics,
Volume 11, 11 2 2011, Pages 39
Delirium risk screening and haloperidol prophylaxis program in hip fracture patients is a helpful tool in identifying high-risk patients, but does not reduce the incidence of delirium.
Vochteloo AJ, Moerman S, van der Burg BL, de Boo M, de Vries MR, Niesten DD, Tuinebreijer WE, Nelissen RG, Pilot P
Background: Delirium in patients with hip fractures lead to higher morbidity and mortality. Prevention in high-risk patients by prescribing low dose haloperidol is currently under investigation. Methods: This prospective cohort surveillance assessed hip fracture patients for risk of developing a delirium with the Risk Model for Delirium (RD) score. High-risk patients (score ≥ 5 points) were treated with a prophylactic low-dose of haloperidol according to hospital protocol. Primary outcome was de...
Abstract
Cited 34 times since 2011 (2.5 per year)
source: EuropePMC
European heart journal,
Volume 33, Issue 9, 10 2 2011, Pages 1076-1084
Galectin-2 expression is dependent on the rs7291467 polymorphism and acts as an inhibitor of arteriogenesis.
van der Laan AM, Schirmer SH, de Vries MR, Koning JJ, Volger OL, Fledderus JO, Bastiaansen AJ, Hollander MR, Baggen JM, Koch KT, Baan J, Henriques JP, van der Schaaf RJ, Vis MM, Mebius RE, van der Pouw Kraan TC, Quax PH, Piek JJ, Horrevoets AJ, van Royen N
Aims: In patients with obstructive coronary artery disease (CAD), the growth of collateral arteries, i.e. arteriogenesis, can preserve myocardial tissue perfusion and function. Monocytes modulate this process, supplying locally the necessary growth factors and degrading enzymes. Knowledge on factors involved in human arteriogenesis is scarce. Thus, the aim of the present study is to identify targets in monocytes that are critical for arteriogenesis in patients with CAD. Methods and results: A to...
Abstract
Cited 26 times since 2011 (1.9 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 24, Issue 10, 6 1 2011, Pages 1126-1133
Comprehensive assessment of changes in left atrial volumes and function after ST-segment elevation acute myocardial infarction: role of two-dimensional speckle-tracking strain imaging.
Antoni ML, Ten Brinke EA, Marsan NA, Atary JZ, Holman ER, van der Wall EE, Schalij MJ, Bax JJ, Delgado V
Background: Left atrial (LA) size has been associated with adverse outcome in patients after acute myocardial infarction. However, data about the occurrence of late LA enlargement and changes in LA function during follow-up are scarce. The purpose of the current study was to evaluate changes in LA size and function during 1-year follow-up. Methods: The study population comprised 407 patients with acute myocardial infarction who were treated with primary percutaneous coronary intervention. At bas...
Abstract
Cited 8 times since 2011 (0.6 per year)
source: EuropePMC
Heart rhythm,
Volume 9, Issue 1, 5 1 2011, Pages 10-17
Catheter ablation of ventricular tachycardia after left ventricular reconstructive surgery for ischemic cardiomyopathy.
Wijnmaalen AP, Roberts-Thomson KC, Steven D, Klautz RJ, Willems S, Schalij MJ, Stevenson WG, Zeppenfeld K
Background: After surgical ventricular restoration (SVR) for ischemic cardiomyopathy, ventricular tachycardias (VTs) are an important reason for postoperative morbidity and mortality. Objective: The purpose of this study was to elucidate the VT substrate, VT characteristics, and outcome of radiofrequency catheter ablation (RFCA) in patients with VT after SVR. Methods: Twelve (3%) of 416 patients referred for RFCA for VT after myocardial infarction in three centers had undergone SVR. After induct...
Abstract
Cited 94 times since 2011 (6.9 per year)
source: EuropePMC
European heart journal,
Volume 33, Issue 16, 4 1 2011, Pages 2098-2108
Aldosterone promotes atrial fibrillation.
Reil JC, Hohl M, Selejan S, Lipp P, Drautz F, Kazakow A, Münz BM, Müller P, Steendijk P, Reil GH, Allessie MA, Böhm M, Neuberger HR
Aims: Hyperaldosteronism is associated with an increased prevalence of atrial fibrillation (AF). However, it is unclear whether this is the consequence of altered haemodynamics or a direct aldosterone effect. It was the aim of the study to demonstrate load-independent effects of aldosterone on atrial structure and electrophysiology. Methods: Osmotic mini-pumps delivering 1.5 µg/h aldosterone were implanted subcutaneously in rats (Aldo). Rats without aldosterone treatment served as controls. Afte...
Abstract
Cited 93 times since 2011 (6.8 per year)
source: EuropePMC
Circulation,
Volume 124, Issue 8, 1 1 2011, Pages 912-919
Cardiac resynchronization therapy as a therapeutic option in patients with moderate-severe functional mitral regurgitation and high operative risk.
van Bommel RJ, Marsan NA, Delgado V, Borleffs CJ, van Rijnsoever EP, Schalij MJ, Bax JJ
Background: Functional mitral regurgitation (MR) is a common finding in heart failure patients with dilated cardiomyopathy and has important prognostic implications. However, the increased operative risk of these patients may result in low referral or high denial rate for mitral valve surgery. Cardiac resynchronization therapy (CRT) has been shown to have a favorable effect on MR. Aims of this study were to (1) evaluate CRT as a therapeutic option in heart failure patients with functional MR and...
Abstract
Cited 4 times since 2011 (0.3 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 97, Issue 15, 1 1 2011, Pages 1268-1276
Pharmacogenetics of antiplatelet therapy: ready for clinical application?
Verschuren JJ, Jukema JW
Abstract
