Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6173 results
Cited 6 times since 2020 (1.4 per year) source: Scopus
International journal of medical informatics, Volume 147, 13 2 2020, Pages 104364 A multi-stakeholder approach to eHealth development: Promoting sustained healthy living among cardiovascular patients. Breeman LD, Keesman M, Atsma DE, Chavannes NH, Janssen V, van Gemert-Pijnen L, Kemps H, Kraaij W, Rauwers F, Reijnders T, Scholte Op Reimer W, Wentzel J, Kraaijenhagen RA, Evers AWM, BENEFIT consortium
Background: Healthy living is key in the prevention and rehabilitation of cardiovascular disease (CVD). Yet, supporting and maintaining a healthy lifestyle is exceptionally difficult and people differ in their needs regarding optimal support for healthy lifestyle interventions. Objective: The goals of this study were threefold: to uncover stakeholders' needs and preferences, to translate these to core values, and develop eHealth technology based on these core values. Our primary research qu... Abstract
Trauma case reports, Volume 31, 11 2 2020, Pages 100379 A 'Final Destination injury': Penetrating trauma of the neck and a pneumomediastinum by a metal part shot from a lawnmower. Quax MLJ, Eefting D, Jansen JC, Blok JJ
Introduction: Outside of war regions, penetrating neck injury is rare. Penetrating neck injury due to a lawnmower has never been described, despite the annual 74.000 injuries caused by lawnmowers in the United States. In this report, the case of a 65-year old women, admitted after a penetrating neck injury due to a metal piece shot from a lawnmower, is described. Report: A 65-year old women, with no relevant medical history, presented at the Emergency Department after she was hit in the neck by... Abstract
Cited 60 times since 2020 (13.8 per year) source: EuropePMC
Circulation. Arrhythmia and electrophysiology, Volume 14, Issue 1, 9 2 2020, Pages e008509 Sudden Cardiac Death Prediction in Arrhythmogenic Right Ventricular Cardiomyopathy: A Multinational Collaboration. Cadrin-Tourigny J, Bosman LP, Wang W, Tadros R, Bhonsale A, Bourfiss M, Lie ØH, Saguner AM, Svensson A, Andorin A, Tichnell C, Murray B, Zeppenfeld K, van den Berg MP, Asselbergs FW, Wilde AAM, Krahn AD, Talajic M, Rivard L, Chelko S, Zimmerman SL, Kamel IR, Crosson JE, Judge DP, Yap SC, Van der Heijden JF, Tandri H, Jongbloed JDH, van Tintelen JP, Platonov PG, Duru F, Haugaa KH, Khairy P, Hauer RNW, Calkins H, Te Riele ASJM, James CA
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with ventricular arrhythmias (VA) and sudden cardiac death (SCD). A model was recently developed to predict incident sustained VA in patients with ARVC. However, since this outcome may overestimate the risk for SCD, we aimed to specifically predict life-threatening VA (LTVA) as a closer surrogate for SCD. Methods: We assembled a retrospective cohort of definite ARVC cases from 15 centers in North America and Europe.... Abstract
Cited 109 times since 2020 (25 per year) source: EuropePMC
Nature communications, Volume 11, Issue 1, 8 2 2020, Pages 6285 Cerebral small vessel disease genomics and its implications across the lifespan. Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Akker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL, Beaudet G, Petit L, Tsuchida A, Zago L, Schilling S, Sigurdsson S, Gottesman RF, Lewis CE, Aggarwal NT, Lopez OL, Smith JA, Valdés Hernández MC, van der Grond J, Wright MJ, Knol MJ, Dörr M, Thomson RJ, Bordes C, Le Grand Q, Duperron MG, Smith AV, Knopman DS, Schreiner PJ, Evans DA, Rotter JI, Beiser AS, Maniega SM, Beekman M, Trollor J, Stott DJ, Vernooij MW, Wittfeld K, Niessen WJ, Soumaré A, Boerwinkle E, Sidney S, Turner ST, Davies G, Thalamuthu A, Völker U, van Buchem MA, Bryan RN, Dupuis J, Bastin ME, Ames D, Teumer A, Amouyel P, Kwok JB, Bülow R, Deary IJ, Schofield PR, Brodaty H, Jiang J, Tabara Y, Setoh K, Miyamoto S, Yoshida K, Nagata M, Kamatani Y, Matsuda F, Psaty BM, Bennett DA, De Jager PL, Mosley TH, Sachdev PS, Schmidt R, Warren HR, Evangelou E
White matter hyperintensities (WMH) are the most common brain-imaging feature of cerebral small vessel disease (SVD), hypertension being the main known risk factor. Here, we identify 27 genome-wide loci for WMH-volume in a cohort of 50,970 older individuals, accounting for modification/confounding by hypertension. Aggregated WMH risk variants were associated with altered white matter integrity (p = 2.5×10-7) in brain images from 1,738 young healthy adults, providing insight into the lifetime imp... Abstract
Cited 1 times since 2020 (0.2 per year) source: EuropePMC
European heart journal. Case reports, Volume 4, Issue 6, 7 1 2020, Pages 1-5 To treat or not to treat: left ventricular thrombus in a patient with cerebral amyloid angiopathy: a case report. Hilt AD, Rasing I, Schalij MJ, Wermer MJH
Background: Cerebral amyloid angiopathy (CAA) is an important cause of cognitive impairment and spontaneous lobar intracerebral haemorrhage in older individuals. When necessary, anticoagulant treatment in these patients comes with two dilemmas; significant intracerebral bleeding risk with treatment vs. high risk of embolic stroke with no treatment. Case summary: A 66-year-old female patient presented to the emergency clinic with a ST-elevation myocardial infarction. Her past medical history reve... Abstract
American journal of physiology. Heart and circulatory physiology, Volume 320, Issue 1, 4 1 2020, Pages H245-H247 A shock-free approach for ambulatory cardioversion in atrial fibrillation. De Coster T
Atrial fibrillation (AF), the most common persistent arrhythmia, is terminated most effectively by electrical cardioversion. This therapy requires in-hospital sedation to relieve the pain caused by electric shocks. Recently, our research group showed how the heart itself could be enabled to detect and terminate arrhythmias, including AF, thereby revealing the discovery of fully biological, shock-free cardioversion. Because of its biological nature, neither electric shocks nor hardware/software i... Abstract
Cited 5 times since 2020 (1.1 per year) source: EuropePMC
International journal of molecular sciences, Volume 21, Issue 23, 3 1 2020, Pages E9244 Assessment of Microvessel Permeability in Murine Atherosclerotic Vein Grafts Using Two-Photon Intravital Microscopy. Baganha F, Ritsma L, Quax PHA, de Vries MR
Plaque angiogenesis and plaque hemorrhage are major players in the destabilization and rupture of atherosclerotic lesions. As these are dynamic processes, imaging of plaque angiogenesis, especially the integrity or leakiness of angiogenic vessels, can be an extremely useful tool in the studies on atherosclerosis pathophysiology. Visualizing plaque microvessels in 3D would enable us to study the architecture and permeability of adventitial and intimal plaque microvessels in advanced atherosclerot... Abstract
Cited 16 times since 2020 (3.7 per year) source: EuropePMC
European journal of pediatrics, Volume 180, Issue 2, 2 1 2020, Pages 617-625 Predictive factors for surgical treatment in preterm neonates with necrotizing enterocolitis: a multicenter case-control study. El Manouni El Hassani S, Niemarkt HJ, Derikx JPM, Berkhout DJC, Ballón AE, de Graaf M, de Boode WP, Cossey V, Hulzebos CV, van Kaam AH, Kramer BW, van Lingen RA, Vijlbrief DC, van Weissenbruch MM, Benninga MA, de Boer NKH, de Meij TGJ
Necrotizing enterocolitis (NEC) is one of the most common and lethal gastrointestinal diseases in preterm infants. Early recognition of infants in need for surgical intervention might enable early intervention. In this multicenter case-control study, performed in nine neonatal intensive care units, preterm born infants (< 30 weeks of gestation) diagnosed with NEC (stage ≥ IIA) between October 2014 and August 2017 were divided into two groups: (1) medical (conservative treatment) and (2) surgi... Abstract
Cited 6 times since 2020 (1.4 per year) source: EuropePMC
JACC. Basic to translational science, Volume 5, Issue 12, 2 1 2020, Pages 1228-1239 Phosphorylcholine Antibodies Preserve Cardiac Function and Reduce Infarct Size by Attenuating the Post-Ischemic Inflammatory Response. Pluijmert NJ, de Jong RCM, de Vries MR, Pettersson K, Atsma DE, Jukema JW, Quax PHA
Phosphorylcholine monoclonal immunoglobulin G antibody attenuates the immediate post-ischemic inflammatory response by reducing the proinflammatory chemokine (C-C motif) ligand 2 chemokine and circulating Ly-6Chi monocytes. This subsequently enhances the post-ischemic repair process, resulting in limited adverse cardiac remodeling and preservation of cardiac function. Therefore, phosphorylcholine monoclonal immunoglobulin G antibody therapy may be a valid therapeutic approach against myocardial... Abstract
Cited 2 times since 2020 (0.5 per year) source: EuropePMC
Chaos (Woodbury, N.Y.), Volume 30, Issue 12, 1 1 2020, Pages 121107 Universal mechanisms for self-termination of rapid cardiac rhythm. Biasci V, Sacconi L, Cytrynbaum EN, Pijnappels DA, De Coster T, Shrier A, Glass L, Bub G
Excitable media sustain circulating waves. In the heart, sustained circulating waves can lead to serious impairment or even death. To investigate factors affecting the stability of such waves, we have used optogenetic techniques to stimulate a region at the apex of a mouse heart at a fixed delay after the detection of excitation at the base of the heart. For long delays, rapid circulating rhythms can be sustained, whereas for shorter delays, there are paroxysmal bursts of activity that start and... Abstract
Cited 3 times since 2020 (0.7 per year) source: EuropePMC
Atherosclerosis. Supplements, Volume 42, 1 1 2020, Pages e65-e71 Improving lipid management in patients with acute coronary syndrome: The ACS Lipid EuroPath tool. Sionis A, Catapano AL, De Ferrari GM, Dudek D, Jukema JW, Landmesser U, Pirillo A, Schiele F, Zaman A, Zamorano JL
Post-acute coronary syndrome (ACS) patients are at very high risk for recurrent events and mortality, despite the availability of effective pharmacological approaches. In 2018, the ACS EuroPath Survey, performed in collaboration with 555 European cardiologists, identified a sub-optimal LDL-C management in post-ACS patients. Based on these premises, the ACS EuroPath II project led to the development of a self-assessment tool to improve lipid management in these very high risk patients, taking int... Abstract
Cited 19 times since 2020 (4.3 per year) source: EuropePMC
Atherosclerosis. Supplements, Volume 42, 1 1 2020, Pages e49-e58 Lipid-lowering therapy and low-density lipoprotein cholesterol goal achievement in patients with acute coronary syndromes: The ACS patient pathway project. Landmesser U, Pirillo A, Farnier M, Jukema JW, Laufs U, Mach F, Masana L, Pedersen TR, Schiele F, Steg G, Tubaro M, Zaman A, Zamorano P, Catapano AL
Background and aims: Post-acute coronary syndrome (ACS) patients are at very high risk for recurrent events and mortality, despite the availability of effective pharmacological approaches. Aim of this survey was to evaluate the compliance to ESC/EAS guidelines during the management of ACS patients and the effectiveness of secondary prevention in seven European countries. Methods: By means of an online questionnaire, data on 2775 ACS patients (either acute case or follow-up patients) were collect... Abstract
Cited 31 times since 2020 (7.1 per year) source: EuropePMC
JAMA cardiology, Volume 5, Issue 12, 1 1 2020, Pages 1338-1348 Stress Myocardial Perfusion Imaging vs Coronary Computed Tomographic Angiography for Diagnosis of Invasive Vessel-Specific Coronary Physiology: Predictive Modeling Results From the Computed Tomographic Evaluation of Atherosclerotic Determinants of Myocardial Ischemia (CREDENCE) Trial. Stuijfzand WJ, van Rosendael AR, Lin FY, Chang HJ, van den Hoogen IJ, Gianni U, Choi JH, Doh JH, Her AY, Koo BK, Nam CW, Park HB, Shin SH, Cole J, Gimelli A, Khan MA, Lu B, Gao Y, Nabi F, Nakazato R, Schoepf UJ, Driessen RS, Bom MJ, Thompson R, Jang JJ, Ridner M, Rowan C, Avelar E, Généreux P, Knaapen P, de Waard GA, Pontone G, Andreini D, Al-Mallah MH, Lu Y, Berman DS, Narula J, Min JK, Bax JJ, Shaw LJ, CREDENCE Investigators
Importance: Stress imaging has been the standard for diagnosing functionally significant coronary artery disease. It is unknown whether novel, atherosclerotic plaque measures improve accuracy beyond coronary stenosis for diagnosing invasive fractional flow reserve (FFR) measurement. Objective: To compare the diagnostic accuracy of comprehensive anatomic (obstructive and nonobstructive atherosclerotic plaque) vs functional imaging measures for estimating vessel-specific FFR. Design, setting, and... Abstract
Cited 4 times since 2020 (0.9 per year) source: EuropePMC
European heart journal, Volume 41, Issue 45, 1 1 2020, Pages 4318-4320 The difficult decision of when and in whom to perform isolated tricuspid valve surgery. Delgado V, Ajmone Marsan N, Bax JJ
Cited 2 times since 2020 (0.5 per year) source: EuropePMC
JACC. Clinical electrophysiology, Volume 6, Issue 14, 1 1 2020, Pages 1794-1796 Automated Functional Substrate Mapping: Further Hurdles to Be Cleared. Zeppenfeld K, Porta-Sánchez A
Huisarts en wetenschap, Volume 63, Issue 12, 30 5 2020, Pages 27-32 E-health bij poliklinische follow-up van myocardinfarctpatiënten. Treskes R, van Winden L, van Keulen N, van der Velde E, Beeres S, Atsma D, Schalij MJ
Cited 2 times since 2020 (0.5 per year) source: EuropePMC
Current cardiology reports, Volume 23, Issue 1, 27 4 2020, Pages 4 Cardiac Sympathetic Innervation Imaging with PET Radiotracers. van der Bijl P, Knuuti J, Delgado V, Bax JJ
Purpose of review: The present article reviews the pathophysiology of cardiac sympathetic denervation, the principles of positron emission tomography (PET) imaging of the sympathetic innervation of the heart and its potential clinical role, based on current and expected future evidence. Recent findings: Imaging of cardiac sympathetic denervation can be performed with radiolabeled noradrenaline analogues, e.g., 11C-hydroxyephedrine. A greater burden of sympathetic denervation carries prognostic s... Abstract
Cited 5 times since 2020 (1.1 per year) source: Scopus
Animals : an open access journal from MDPI, Volume 10, Issue 12, 26 4 2020, Pages E2214 Social Context Influences Resting Physiology in Dogs. Kortekaas K, Kotrschal K
Domestication has affected the social life of dogs. They seem to be less dependent on their pack members than wolves, potentially causing dogs to be more alert towards their environment, especially when resting. Such a response has been found in dogs resting alone compared to wolves in the same situation. However, as this may be influenced by social context, we compared alertness (i.e., degree of activation along the sleep-wake continuum-measured via cardiac parameters) of pack-living and enclos... Abstract
Cited 47 times since 2020 (10.7 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 14, Issue 4, 25 4 2020, Pages 854-866 Neo-LVOT and Transcatheter Mitral Valve Replacement: Expert Recommendations. Reid A, Ben Zekry S, Turaga M, Tarazi S, Bax JJ, Wang DD, Piazza N, Bapat VN, Ihdayhid AR, Cavalcante JL, Blanke P, Leipsic J
With the advent of transcatheter mitral valve replacement (TMVR), the concept of the neo-left ventricular outflow tract (LVOT) was introduced and remains an essential component of treatment planning. This paper describes the LVOT anatomy and provides a step-by-step computed tomography methodology to segment and measure the neo-LVOT while discussing the current evidence and outstanding challenges. It also discusses the technical and hemodynamic factors that play a major role in assessing the neo-... Abstract
Cited 4 times since 2020 (0.9 per year) source: Scopus
Frontiers in psychology, Volume 11, 24 4 2020, Pages 568199 Context-Specific Arousal During Resting in Wolves and Dogs: Effects of Domestication? Jean-Joseph H, Kortekaas K, Range F, Kotrschal K
Due to domestication, dogs differ from wolves in the way they respond to their environment, including to humans. Selection for tameness and the associated changes to the autonomic nervous system (ANS) regulation have been proposed as the primary mechanisms of domestication. To test this idea, we compared two low-arousal states in equally raised and kept wolves and dogs: resting, a state close to being asleep, and inactive wakefulness, which together take up an important part in the time budgets... Abstract