6173 results
Cited 11 times since 2001 (0.5 per year)
source: EuropePMC
Respiratory medicine,
Volume 95, Issue 10, 1 1 2001, Pages 802-805
Delays in the diagnosis and treatment of hospitalized patients with smear-positive pulmonary tuberculosis.
Yilmaz A, Boğa S, Sulu E, Durucu M, Yilmaz D, Baran A, Poluman A
The aim of present study was to investigate whether there was any delay in the diagnosis and treatment of inpatients with smear-positive pulmonary tuberculosis followed-up in our centre. We reviewed clinical records in February 1999 and identified 134 hospitalized patients with smear-positive pulmonary tuberculosis. Clinical files of the patients were analysed and a questionnaire was completed. Several intervals and delays were calculated. Median application interval was 17.5 days [95% confidenc...
Abstract
Cited 34 times since 2001 (1.4 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 21, Issue 10, 1 1 2001, Pages 1630-1635
Raman spectroscopic evaluation of the effects of diet and lipid-lowering therapy on atherosclerotic plaque development in mice.
van De Poll SW, Römer TJ, Volger OL, Delsing DJ, Bakker Schut TC, Princen HM, Havekes LM, Jukema JW, van Der Laarse A, Puppels GJ
Quantitative characterization of atherosclerotic plaque composition with standard histopathological methods remains limited to sectioned plaques. Raman spectroscopy enables nondestructive quantification of atherosclerotic plaque composition. We used Raman spectroscopy to study the effects of diet and lipid-lowering therapy on plaque development in apolipoprotein (APO) E*3-Leiden transgenic mice. Raman spectra were obtained over the full width and entire length of the ascending aorta and aortic a...
Abstract
Cited 8 times since 2001 (0.3 per year)
source: EuropePMC
Cardiovascular research,
Volume 51, Issue 4, 1 1 2001, Pages 729-735
The volume-dependency of parallel conductance throughout the cardiac cycle and its consequence for volume estimation of the left ventricle in patients.
Kornet L, Schreuder JJ, van der Velde ET, Jansen JR
Objective: To study the hypothesis that the electrical conductance of tissues and fluids (parallel conductance (G(p))) around the ventricle depends on left ventricular volume throughout the cardiac cycle. Methods: We extended a recently developed method to determine G(p) throughout the cardiac cycle. First, we compared the estimates of parallel conductances obtained with the new method (G(a)(p)) with those of the conventional one (G(1)(p)), both averaged over the cardiac cycles. Secondly, G(a)(p...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 9, Issue 6, 1 1 2001, Pages 256-261
Scientific conference on therapeutic angiogenesis and myocardial laser revascularisation: Santa Fe, United States, 24-27 January 2001.
Palmen M, Dekkers SC
Abstract
Cited 1 times since 2001 (0 per year)
source: EuropePMC
American journal of surgery,
Volume 182, Issue 3, 1 1 2001, Pages 305-306
Prospective trial of computed tomography and ultrasonography for diagnosing appendicitis in the atypical patient.
Poortman P, Hamming JF
Abstract
Cited 9 times since 2001 (0.4 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 122, Issue 3, 1 1 2001, Pages 449-456
Prime solutions for cardiopulmonary bypass in neonates: antioxidant capacity of prime based on albumin or fresh frozen plasma.
Molicki JS, Draaisma AM, Verbeet N, Munneke R, Huysmans HA, Hazekamp MG, Berger HM
Objective: Oxidative damage and inflammation are believed to play an important role in postoperative complications after cardiopulmonary bypass. During bypass, a prime solution with a high antioxidant capacity may reduce the oxidative damage and inflammation. We investigated total antioxidant capacity and individual scavengers during the preparation of 2 different prime solutions. Methods: The prime solutions were prepared with either pasteurized human albumin or fresh frozen plasma. The total a...
Abstract
Cited 22 times since 2001 (0.9 per year)
source: EuropePMC
Virology,
Volume 288, Issue 2, 1 1 2001, Pages 236-246
Generation of a high-capacity hybrid vector: packaging of recombinant adenoassociated virus replicative intermediates in adenovirus capsids overcomes the limited cloning capacity of adenoassociated virus vectors.
Gonçalves MA, Pau MG, de Vries AA, Valerio D
Gene therapy aims to complement or, ideally, correct defective genes. The broad clinical application of this emerging technology requires the development of safe high-capacity gene delivery vehicles that combine efficient transduction of dividing as well as quiescent cells with sustained transgene expression. Here we present a new hybrid vector system that unites favorable attributes of adenoassociated virus (AAV) and adenovirus (Ad) vectors in a single particle. This was achieved by inclusion o...
Abstract
Cited 23 times since 2001 (1 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 24, Issue 9 Pt 1, 1 1 2001, Pages 1334-1342
Three-dimensional distribution of bipolar atrial electrogram voltages in patients with congenital heart disease.
De Groot NM, Kuijper AF, Blom NA, Bootsma M, Schalij MJ
Voltage differences might be used to distinguish normal atrial tissue from abnormal atrial tissue. This study was aimed at identifying lowest voltage areas in patients with atrial tachycardia after surgical correction of congenital heart disease and to evaluate if identification of these areas in diseased hearts facilitates selection of critical conduction pathways in reentrant circuits as target sites for catheter ablation. Ten patients (four men, age 39 +/- 15 years) with normal sized atria an...
Abstract
Cited 86 times since 2001 (3.6 per year)
source: EuropePMC
American journal of physiology. Heart and circulatory physiology,
Volume 281, Issue 2, 1 1 2001, Pages H755-63
Hypertonic saline method accurately determines parallel conductance for dual-field conductance catheter.
Steendijk P, Staal E, Jukema JW, Baan J
Conversion of conductance catheter data to absolute ventricular volumes requires assessment of parallel conductance (G(P)). We determined the accuracy of GP obtained by the hypertonic saline method (G(P)saline) compared with angiographically derived GP (G(P)Angio) and quantified the variabilities of GP for the dual-field conductance catheter method in nine anesthetized sheep studied at baseline, treated with dobutamine, and subjected to volume loading and beta-blockade. G(P)saline and G(P)Angio...
Abstract
Cited 155 times since 2001 (6.5 per year)
source: EuropePMC
The EMBO journal,
Volume 20, Issue 16, 1 1 2001, Pages 4588-4602
Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus.
Schepers A, Ritzi M, Bousset K, Kremmer E, Yates JL, Harwood J, Diffley JF, Hammerschmidt W
Epstein-Barr virus (EBV) replicates in its latent phase once per cell cycle in proliferating B cells. The latent origin of DNA replication, oriP, supports replication and stable maintenance of the EBV genome. OriP comprises two essential elements: the dyad symmetry (DS) and the family of repeats (FR), both containing clusters of binding sites for the transactivator EBNA1. The DS element appears to be the functional replicator. It is not yet understood how oriP-dependent replication is integrated...
Abstract
Cited 1 times since 2001 (0 per year)
source: EuropePMC
Kidney international,
Volume 60, Issue 1, 1 1 2001, Pages 117-125
Adenovirus-mediated transfer of the 39 kD receptor-associated protein increases fibrinolytic capacity.
Goedde MF, Grimbergen JM, Toet KH, Sitter T, Quax PH, Kooistra T
Background: The mesothelium has an important role in maintaining an adequate fibrinolytic capacity in the peritoneal cavity and thus in preventing the formation of fibrinous peritoneal adhesions by secreting the fibrinolytic enzyme tissue-type plasminogen activator (t-PA). The fibrinolytic activity of human mesothelial cells (HMCs) is counteracted by rapid uptake of t-PA via the low-density lipoprotein receptor-related protein (LRP). The 39 kD receptor-associated protein (RAP) is an inhibitor of...
Abstract
Cited 4 times since 2001 (0.2 per year)
source: EuropePMC
Cardiovascular research,
Volume 51, Issue 1, 1 1 2001, Pages 122-130
Oxygen wastage of stunned myocardium in vivo is due to an increased oxygen cost of contractility and a decreased myofibrillar efficiency.
Trines SA, Slager CJ, Onderwater TA, Lamers JM, Verdouw PD, Krams R
Objective: We investigated whether an increased oxygen cost of contractility and/or a decreased myofibrillar efficiency contribute to oxygen wastage of stunned myocardium. Because Ca(2+)-sensitizers may increase myofibrillar Ca(2+)-sensitivity without increasing cross-bridge cycling, we also investigated whether EMD 60263 restores myofibrillar efficiency and/or the oxygen cost of contractility. Methods: Regional fiber stress and strain were calculated from mesomyocardially implanted ultrasound c...
Abstract
Journal of the American College of Cardiology,
Volume 38, Issue 1, 1 1 2001, Pages 286
Batista's operation: what have we learned?
Schreuder JJ, Steendijk P, Baan J, Alfieri O
Abstract
Cited 50 times since 2001 (2.1 per year)
source: EuropePMC
Pediatric cardiology,
Volume 22, Issue 4, 1 1 2001, Pages 321-326
Acute renal insufficiency and renal replacement therapy after pediatric cardiopulmonary bypass surgery.
Kist-van Holthe tot Echten JE, Goedvolk CA, Doornaar MB, van der Vorst MM, Bosman-Vermeeren JM, Brand R, van der Heijden AJ, Schoof PH, Hazekamp MG
The aim of the study was to investigate renal function and renal replacement therapy after cardiopulmonary bypass surgery in children. Patient characteristics (sex, age, diagnosis), operation type, and death were listed. The study was performed retrospectively using serum creatinine level before, and peak values after, cardiopulmonary bypass surgery for assessment of renal function. Of the children on renal replacement therapy, indication, efficacy, and complications were recorded. In a 5-year p...
Abstract
Cited 35 times since 2001 (1.5 per year)
source: EuropePMC
Acta physiologica Scandinavica,
Volume 172, Issue 2, 1 1 2001, Pages 97-106
Acute effects of pulmonary artery banding in sheep on right ventricle pressure-volume relations: relevance to the arterial switch operation.
Hon JK, Steendijk P, Khan H, Wong K, Yacoub M
The first stage of the two-stage arterial switch operation (ASO) for transposition of the great arteries (TGA) is associated with depressed ventricular function and an unstable immediate post-operative course. It is unclear if this is because of the acute increase in afterload of the thin-walled, low-pressure ventricle by pulmonary artery banding (PAB). To determine the acute effects of afterload increase on the contractile function of thin-walled ventricles, we studied the right ventricular pre...
Abstract
Cited 13 times since 2001 (0.5 per year)
source: EuropePMC
European journal of heart failure,
Volume 3, Issue 3, 1 1 2001, Pages 331-333
Carvedilol increases plasma vascular endothelial growth factor (VEGF) in patients with chronic heart failure.
de Boer RA, Siebelink HJ, Tio RA, Boomsma F, van Veldhuisen DJ
Abstract
Cited 19 times since 2001 (0.8 per year)
source: EuropePMC
The Biochemical journal,
Volume 356, Issue Pt 3, 1 1 2001, Pages 907-910
Cloning and characterization of human liver cytosolic beta-glycosidase.
de Graaf M, van Veen IC, van der Meulen-Muileman IH, Gerritsen WR, Pinedo HM, Haisma HJ
Cytosolic beta-glucosidase (EC 3.2.1.21) from mammalian liver is a member of the family 1 glycoside hydrolases and is known for its ability to hydrolyse a range of beta-D-glycosides, including beta-D-glucoside and beta-D-galactoside. We therefore refer to this enzyme as cytosolic beta-glycosidase. We cloned the cDNA encoding the human cytosolic beta-glycosidase by performing PCR on cDNA prepared from total human liver RNA. Specific primers were based on human expressed sequence tags found in the...
Abstract
Cited 31 times since 2001 (1.3 per year)
source: EuropePMC
Radiology,
Volume 219, Issue 3, 1 1 2001, Pages 637-643
Aortic valve replacement in patients with aortic valve stenosis improves myocardial metabolism and diastolic function.
Beyerbacht HP, Lamb HJ, van Der Laarse A, Vliegen HW, Leujes F, Hazekamp MG, de Roos A, van Der Wall EE
Purpose: To evaluate whether functional and metabolic changes recover after aortic valve replacement (AVR). Materials and methods: Eighteen men with aortic valve stenosis (mean pressure gradient +/- SD, 79.9 mm Hg +/- 15.1) underwent magnetic resonance (MR) imaging and phosphorus 31 MR spectroscopy. In nine patients who underwent AVR, MR imaging and spectroscopy were repeated 40 weeks +/- 12 after AVR. Ten age-matched healthy men were control subjects. Results: Before AVR, the myocardial phospho...
Abstract
Cited 20 times since 2001 (0.8 per year)
source: EuropePMC
Virology,
Volume 284, Issue 2, 1 1 2001, Pages 259-276
Recombinant equine arteritis virus as an expression vector.
de Vries AA, Glaser AL, Raamsman MJ, Rottier PJ
Equine arteritis virus (EAV) is the prototypic member of the family Arteriviridae, which together with the Corona- and Toroviridae constitutes the order Nidovirales. A common trait of these positive-stranded RNA viruses is the 3'-coterminal nested set of six to eight leader-containing subgenomic mRNAs which are generated by a discontinuous transcription mechanism and from which the viral open reading frames downstream of the polymerase gene are expressed. In this study, we investigated whet...
Abstract
Cited 7 times since 2001 (0.3 per year)
source: EuropePMC
The British journal of surgery,
Volume 88, Issue 6, 1 1 2001, Pages 884-886
Totally extraperitoneal endoscopic repair of recurrent inguinal hernia.
van der Hem JA, Hamming JF, Meeuwis JD, Oostvogel HJ
Background: Conventional repair of recurrent inguinal hernia is associated with a re-recurrence rate as high as 35 per cent. Endoscopic mesh repair has promising results regarding both recurrence and complication rates. Methods: In a retrospective review, the results of endoscopic totally extraperitoneal repair were evaluated in 104 patients with 108 recurrent hernias. Follow-up was at least 1 year. Type of recurrence, time of occurrence after previous repair, duration of surgery, complications,...
Abstract
