Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6196 results
Cited 3 times since 2017 (0.4 per year) source: EuropePMC
Nature genetics, Volume 49, Issue 8, 1 1 2017, Pages 1286 Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, Low SK, Weeke PE, Müller-Nurasyid M, Smith JG, Brody JA, Niemeijer MN, Dörr M, Trompet S, Huffman J, Gustafsson S, Schurmann C, Kleber ME, Lyytikäinen LP, Seppälä I, Malik R, R V R Horimoto A, Perez M, Sinisalo J, Aeschbacher S, Thériault S, Yao J, Radmanesh F, Weiss S, Teumer A, Choi SH, Weng LC, Clauss S, Deo R, Rader DJ, Shah SH, Sun A, Hopewell JC, Debette S, Chauhan G, Yang Q, Worrall BB, Paré G, Kamatani Y, Hagemeijer YP, Verweij N, Siland JE, Kubo M, Smith JD, Van Wagoner DR, Bis JC, Perz S, Psaty BM, Ridker PM, Magnani JW, Harris TB, Launer LJ, Shoemaker MB, Padmanabhan S, Haessler J, Bartz TM, Waldenberger M, Lichtner P, Arendt M, Krieger JE, Kähönen M, Risch L, Mansur AJ, Peters A, Smith BH, Lind L, Scott SA, Lu Y, Bottinger EB, Hernesniemi J, Lindgren CM, Wong JA, Huang J, Eskola M, Morris AP, Ford I, Reiner AP, Delgado G, Chen LY, Chen Y
Cited 11 times since 2017 (1.4 per year) source: EuropePMC
The British journal of surgery, Volume 104, Issue 8, 1 1 2017, Pages 964-976 Systematic review of mortality risk prediction models in the era of endovascular abdominal aortic aneurysm surgery. Lijftogt N, Luijnenburg TWF, Vahl AC, Wilschut ED, Leijdekkers VJ, Fiocco MF, Wouters MWJM, Hamming JF
Background: The introduction of endovascular aneurysm repair (EVAR) has reduced perioperative mortality after abdominal aortic aneurysm (AAA) surgery. The objective of this systematic review was to assess existing mortality risk prediction models, and identify which are most useful for patients undergoing AAA repair by either EVAR or open surgical repair. Methods: A systematic search of the literature was conducted for perioperative mortality risk prediction models for patients with AAA publishe... Abstract
Cited 35 times since 2017 (4.5 per year) source: EuropePMC
European heart journal, Volume 38, Issue 28, 1 1 2017, Pages 2177-2183 Standards defining a 'Heart Valve Centre': ESC Working Group on Valvular Heart Disease and European Association for Cardiothoracic Surgery Viewpoint. Chambers JB, Prendergast B, Iung B, Rosenhek R, Zamorano JL, Piérard LA, Modine T, Falk V, Kappetein AP, Pibarot P, Sundt T, Baumgartner H, Bax JJ, Lancellotti P
Cited 3 times since 2017 (0.4 per year) source: EuropePMC
European heart journal, Volume 38, Issue 28, 1 1 2017, Pages 2208-2210 Further insight into transcatheter and surgical aortic bioprosthetic valve thrombosis. Bax JJ, Delgado V
Cited 12 times since 2017 (1.5 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 10, Issue 7, 1 1 2017, Pages e005670 Relationship Between Myocardial Function, Body Mass Index, and Outcome After ST-Segment-Elevation Myocardial Infarction. Joyce E, Hoogslag GE, Kamperidis V, Debonnaire P, Katsanos S, Mertens B, Marsan NA, Bax JJ, Delgado V
Background: Better survival for overweight and obese patients after ST-segment-elevation myocardial infarction (STEMI) has been demonstrated. The association between body mass index (BMI), outcome, and left ventricular (LV) structure and function after STEMI, including LV longitudinal strain (global longitudinal strain), was evaluated. Methods and results: First patients with STEMI undergoing primary percutaneous coronary intervention (n=1604; mean age, 61±12 years; 75% men) had BMI measured on... Abstract
Cited 34 times since 2017 (4.3 per year) source: EuropePMC
Rheumatology (Oxford, England), Volume 56, Issue 7, 1 1 2017, Pages 1081-1088 Predicting cardiopulmonary involvement in patients with systemic sclerosis: complementary value of nailfold videocapillaroscopy patterns and disease-specific autoantibodies. Markusse IM, Meijs J, de Boer B, Bakker JA, Schippers HPC, Schouffoer AA, Ajmone Marsan N, Kroft LJM, Ninaber MK, Huizinga TWJ, de Vries-Bouwstra JK
Objective: To evaluate the prevalence of anti-extractable nuclear antigen (anti-ENA) antibodies in Dutch SSc patients and the predictive power of the combination of specific anti-ENA antibodies and nailfold videocapillaroscopy (NVC) patterns to improve identification of patients with high risk for cardiopulmonary involvement. Methods: A total of 287 patients (79%) from the Leiden SSc-Cohort had data available on NVC-pattern (no SSc-specific, early, active, late) and anti-ENA antibodies. Associat... Abstract
Cited 10 times since 2017 (1.3 per year) source: EuropePMC
International journal of cardiology, Volume 244, 27 4 2017, Pages 298-302 Chronic use of low-dose aspirin is not associated with lower bone mineral density in the general population. Bonten TN, de Mutsert R, Rosendaal FR, Jukema JW, van der Bom JG, de Jongh RT, den Heijer M
Background: Low-dose aspirin is the cornerstone of secondary prevention of cardiovascular disease. Previous studies suggested that the use of aspirin is associated with an increased fracture risk. However, there is uncertainty whether this is due to an effect of aspirin on bone mineral density (BMD). Methods: Between 2008 and 2012, information on medication use and dual X-ray absorptiometry measured vertebral and femoral BMD of 916 participants was collected in the Netherland Epidemiology of Obe... Abstract
Cited 15 times since 2017 (1.9 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 33, Issue 11, 24 4 2017, Pages 1809-1819 Automatic identification of coronary tree anatomy in coronary computed tomography angiography. Cao Q, Broersen A, de Graaf MA, Kitslaar PH, Yang G, Scholte AJ, Lelieveldt BPF, Reiber JHC, Dijkstra J
An automatic coronary artery tree labeling algorithm is described to identify the anatomical segments of the extracted centerlines from coronary computed tomography angiography (CCTA) images. This method will facilitate the automatic lesion reporting and risk stratification of cardiovascular disease. Three-dimensional (3D) models for both right dominant (RD) and left dominant (LD) coronary circulations were built. All labels in the model were matched with their possible candidates in the extract... Abstract
Cited 33 times since 2017 (4.2 per year) source: EuropePMC
Journal of cardiovascular computed tomography, Volume 11, Issue 5, 23 4 2017, Pages 383-388 Interpreting results of coronary computed tomography angiography-derived fractional flow reserve in clinical practice. Rabbat MG, Berman DS, Kern M, Raff G, Chinnaiyan K, Koweek L, Shaw LJ, Blanke P, Scherer M, Jensen JM, Lesser J, Nørgaard BL, Pontone G, De Bruyne B, Bax JJ, Leipsic J
The application of computational fluid dynamics to coronary computed tomography angiography allows Fractional Flow Reserve (FFR) to be calculated non-invasively (FFRCT), enabling computation of FFR from coronary computed tomography angiography acquired at rest both for individual lesions as well as along the entire course of a coronary artery. FFRCT, validated in a number of accuracy studies and a large clinical utility trial, is beginning to penetrate clinical practice. Importantly, while accur... Abstract
Cited 23 times since 2017 (2.9 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 33, Issue 9, 22 4 2017, Pages 1305-1312 Accuracy and reproducibility of fast fractional flow reserve computation from invasive coronary angiography. van Rosendael AR, Koning G, Dimitriu-Leen AC, Smit JM, Montero-Cabezas JM, van der Kley F, Jukema JW, Reiber JHC, Bax JJ, Scholte AJHA
Fractional flow reserve (FFR) guided percutaneous coronary intervention (PCI) is associated with favourable outcome compared with revascularization based on angiographic stenosis severity alone. The feasibility of the new image-based quantitative flow ratio (QFR) assessed from 3D quantitative coronary angiography (QCA) and thrombolysis in myocardial infarction (TIMI) frame count using three different flow models has been reported recently. The aim of the current study was to assess the accuracy,... Abstract
Cited 42 times since 2017 (5.3 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 34, Issue 1, 22 4 2017, Pages 97-112 Cardiovascular magnetic resonance imaging to assess myocardial fibrosis in valvular heart disease. Podlesnikar T, Delgado V, Bax JJ
The left ventricular (LV) remodeling process associated with significant valvular heart disease (VHD) is characterized by an increase of myocardial interstitial space with deposition of collagen and loss of myofibers. These changes occur before LV systolic function deteriorates or the patient develops symptoms. Cardiovascular magnetic resonance (CMR) permits assessment of reactive fibrosis, with the use of T1 mapping techniques, and replacement fibrosis, with the use of late gadolinium contrast... Abstract
Cited 4 times since 2017 (0.5 per year) source: EuropePMC
The American journal of cardiology, Volume 120, Issue 5, 15 3 2017, Pages 734-739 Comparison of Left Ventricular Function and Myocardial Infarct Size Determined by 2-Dimensional Speckle Tracking Echocardiography in Patients With and Without Chronic Obstructive Pulmonary Disease After ST-Segment Elevation Myocardial Infarction. Goedemans L, Abou R, Hoogslag GE, Ajmone Marsan N, Taube C, Delgado V, Bax JJ
Patients with chronic obstructive pulmonary disease (COPD) have a high risk of mortality after acute ST-segment elevation myocardial infarction (STEMI). We compared STEMI patients with versus without COPD in terms of infarct size and left ventricular (LV) systolic function using advanced 2-dimensional speckle tracking echocardiography. Of 1,750 patients with STEMI (mean age 61 ± 12 years, 76% male), 133 (7.6%) had COPD. With transthoracic echocardiography, left ventricular ejection fraction (LVE... Abstract
Cited 163 times since 2017 (20.6 per year) source: EuropePMC
European journal of heart failure, Volume 19, Issue 12, 8 2 2017, Pages 1664-1671 Right ventricular dysfunction in left-sided heart failure with preserved versus reduced ejection fraction. Bosch L, Lam CSP, Gong L, Chan SP, Sim D, Yeo D, Jaufeerally F, Leong KTG, Ong HY, Ng TP, Richards AM, Arslan F, Ling LH
Background: Right ventricular (RV) dysfunction is recognized as a major prognostic factor in left-sided heart failure (HF). However, the relative contribution of RV dysfunction in HF with preserved (HFpEF) vs. reduced ejection fraction (HFrEF) is unclear. Methods and results: Right ventricular longitudinal strain (RVLS), tricuspid annular plane systolic excursion (TAPSE) and pulmonary artery systolic pressure (PASP) were determined by echocardiography in 657 age- and gender-matched groups of pat... Abstract
Cited 12 times since 2017 (1.5 per year) source: EuropePMC
Journal of clinical research in pediatric endocrinology, Volume 9, Issue 4, 7 1 2017, Pages 366-370 Successful Growth Hormone Therapy in Cornelia de Lange Syndrome. de Graaf M, Kant SG, Wit JM, Willem Redeker EJ, Eduard Santen GW, Henriëtta Verkerk AJM, Uitterlinden AG, Losekoot M, Oostdijk W
Cornelia de Lange syndrome (CdLS) is a both clinically and genetically heterogeneous syndrome. In its classical form, it is characterised by distinctive facial features, intra-uterine growth retardation, short stature, developmental delay, and anomalies in multiple organ systems. NIPBL, SMC1A, SMC3, RAD21 and HDAC8, all involved in the cohesin pathway, have been identified to cause CdLS. Growth hormone (GH) secretion has been reported as normal, and to our knowledge, there are no reports on the... Abstract
Cited 6 times since 2017 (0.8 per year) source: EuropePMC
International journal of cardiology, Volume 243, 2 1 2017, Pages 191-193 Clinical course of tricuspid regurgitation in repaired tetralogy of Fallot. Woudstra OI, Bokma JP, Winter MM, Kiès P, Jongbloed MRM, Vliegen HW, Groenink M, Meijboom FJ, Mulder BJM, Bouma BJ
Background: Little is known on the clinical course of tricuspid regurgitation (TR) in patients with repaired tetralogy of Fallot (rTOF) and which patients are at particular risk. This study aims to determine TR course, characteristics associated with TR progression, and the prognostic relevance of TR in rTOF patients. Methods: In this dualcenter cohort study, rTOF patients from a prospective national registry with ≥1 cardiac magnetic resonance imaging study and ≥2 echocardiograms available were... Abstract
Cited 41 times since 2017 (5.2 per year) source: EuropePMC
JAMA cardiology, Volume 2, Issue 6, 1 1 2017, Pages 678-683 Value of Cardiovascular Magnetic Resonance Imaging in Noninvasive Risk Stratification in Tetralogy of Fallot. Bokma JP, de Wilde KC, Vliegen HW, van Dijk AP, van Melle JP, Meijboom FJ, Zwinderman AH, Groenink M, Mulder BJM, Bouma BJ
Importance: Adults late after total correction of tetralogy of Fallot (TOF) are at risk for major complications. Cardiovascular magnetic resonance (CMR) imaging is recommended to quantify right ventricular (RV) and left ventricular (LV) function. However, a commonly used risk model by Khairy et al requires invasive investigations and lacks CMR imaging to identify high-risk patients. Objective: To implement CMR imaging in noninvasive risk stratification to predict major adverse clinical outcomes.... Abstract
Cited 24 times since 2017 (3 per year) source: EuropePMC
Human molecular genetics, Volume 26, Issue 12, 1 1 2017, Pages 2346-2363 Discovery of novel heart rate-associated loci using the Exome Chip. van den Berg ME, Warren HR, Cabrera CP, Verweij N, Mifsud B, Haessler J, Bihlmeyer NA, Fu YP, Weiss S, Lin HJ, Grarup N, Li-Gao R, Pistis G, Shah N, Brody JA, Müller-Nurasyid M, Lin H, Mei H, Smith AV, Lyytikäinen LP, Hall LM, van Setten J, Trompet S, Prins BP, Isaacs A, Radmanesh F, Marten J, Entwistle A, Kors JA, Silva CT, Alonso A, Bis JC, de Boer R, de Haan HG, de Mutsert R, Dedoussis G, Dominiczak AF, Doney ASF, Ellinor PT, Eppinga RN, Felix SB, Guo X, Hagemeijer Y, Hansen T, Harris TB, Heckbert SR, Huang PL, Hwang SJ, Kähönen M, Kanters JK, Kolcic I, Launer LJ, Li M, Yao J, Linneberg A, Liu S, Macfarlane PW, Mangino M, Morris AD, Mulas A, Murray AD, Nelson CP, Orrú M, Padmanabhan S, Peters A, Porteous DJ, Poulter N, Psaty BM, Qi L, Raitakari OT, Rivadeneira F, Roselli C, Rudan I, Sattar N, Sever P, Sinner MF, Soliman EZ, Spector TD, Stanton AV, Stirrups KE, Taylor KD, Tobin MD, Uitterlinden A, Vaartjes I, Hoes AW, van der Meer P, Völker U, Waldenberger M, Xie Z, Zoledziewska M, Tinker A, Polasek O, Rosa
Resting heart rate is a heritable trait, and an increase in heart rate is associated with increased mortality risk. Genome-wide association study analyses have found loci associated with resting heart rate, at the time of our study these loci explained 0.9% of the variation. This study aims to discover new genetic loci associated with heart rate from Exome Chip meta-analyses.Heart rate was measured from either elecrtrocardiograms or pulse recordings. We meta-analysed heart rate association resul... Abstract
Cited 8 times since 2017 (1 per year) source: EuropePMC
Acta dermato-venereologica, Volume 97, Issue 6, 1 1 2017, Pages 724-730 Risk of Non-melanoma Skin Cancer in Patients with Atopic Dermatitis Treated with Oral Immunosuppressive Drugs. Garritsen FM, van der Schaft J, van den Reek JM, Politiek K, van Os-Medendorp H, van Dijk M, Hijnen DJ, de Graaf M, Bruijnzeel-Koomen CA, de Jong EM, Schuttelaar MA, Bruin-Weller MS
There is uncertainty about the risk of developing non-melanoma skin cancer (NMSC), including basal cell carcinoma and squamous cell carcinoma (SCC), in patients with atopic dermatitis (AD) treated with oral immunosuppressive drugs. A total of 557 patients with AD treated with these drugs in the University Medical Center Utrecht and Groningen, the Netherlands, were analysed. NMSC after oral immunosuppressive treatment was reported in 18 patients (3.2%). The standardized incidence ratio for develo... Abstract
Cited 10 times since 2017 (1.3 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 51, Issue 6, 1 1 2017, Pages 1100-1107 Extensive infective endocarditis of the aortic root and the aortic-mitral continuity: a mitral valve sparing approach†. Tomšic A, Schneider AW, Palmen M, van Brakel TJ, Versteegh MIM, Klautz RJM
Objectives: Severe cases of infective endocarditis (IE) of the aortic valve can cause aortic root destruction and affect the surrounding structures, including the aortic-mitral continuity, the anterior mitral valve leaflet and the roof of the left atrium. Reconstruction after resection of all infected tissue remains challenging. We describe our surgical approach and the mid-term results. Methods: Between January 2004 and December 2015, 35 patients underwent surgery for extensive IE of the aortic... Abstract
Cited 15 times since 2017 (1.9 per year) source: EuropePMC
European heart journal, Volume 38, Issue 21, 1 1 2017, Pages 1632-1637 Improving public health by improving clinical trial guidelines and their application. Landray MJ, Bax JJ, Alliot L, Buyse M, Cohen A, Collins R, Hindricks G, James SK, Lane S, Maggioni AP, Meeker-O'Connell A, Olsson G, Pocock SJ, Rawlins M, Sellors J, Shinagawa K, Sipido KR, Smeeth L, Stephens R, Stewart MW, Stough WG, Sweeney F, Van de Werf F, Woods K, Casadei B
Evidence generated from randomized controlled trials forms the foundation of cardiovascular therapeutics and has led to the adoption of numerous drugs and devices that prolong survival and reduce morbidity, as well as the avoidance of interventions that have been shown to be ineffective or even unsafe. Many aspects of cardiovascular research have evolved considerably since the first randomized trials in cardiology were conducted. In order to be large enough to provide reliable evidence about eff... Abstract