6139 results
Cited 5 times since 2010 (0.4 per year)
source: EuropePMC
Atherosclerosis,
Volume 215, Issue 1, 8 2 2010, Pages 125-129
Mannose binding lectin 2 haplotypes do not affect the progression of coronary atherosclerosis in men with proven coronary artery disease treated with pravastatin.
Alipour A, Cabezas MC, Elte JW, Vallvé JC, Ribalta J, Zwinderman AH, Defesche JC, Jukema JW
Objective: Mannose binding lectin (MBL) is one of the three initiators of complement activation. Polymorphisms of the MBL2 gene and its promoter, and especially haplotypes, determine MBL plasma levels. MBL deficiency has been associated with the development of atherosclerosis. We evaluated whether the rate of angiographic progression of coronary atherosclerosis during pravastatin treatment was associated with MBL2 haplotypes in REGRESS, a placebo-controlled 2 years intervention study. Methods: T...
Abstract
Cited 9 times since 2010 (0.6 per year)
source: EuropePMC
European heart journal,
Volume 32, Issue 3, 7 1 2010, Pages 365-370
Influence of smoking on the prognostic value of cardiovascular computed tomography coronary angiography.
van Werkhoven JM, Schuijf JD, Pazhenkottil AP, Herzog BA, Ghadri JR, Jukema JW, Boersma E, Kroft LJ, de Roos A, Kaufmann PA, Bax JJ
Aims: Computed tomography coronary angiography (CTA) is an important non-invasive imaging modality increasingly used for the diagnosis and prognosis of coronary artery disease (CAD). The purpose of the current study was to determine the influence of smoking status on the prognostic value of CTA in patients with suspected or known CAD. Methods and results: In 1207 patients (57% male, age 57 ± 12 years) referred for CTA, the presence of significant CAD (≥ 50% stenosis) was determined. During follo...
Abstract
Cited 3 times since 2010 (0.2 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 28, Issue 1, 7 1 2010, Pages 193-197
320-row CT scanning: reduction in tube current parallels reduction in radiation exposure?
van der Wall EE, van Velzen JE, de Graaf FR, Jukema JW, Schuijf JD, Bax JJ
Abstract
Cited 13 times since 2010 (0.9 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 97, Issue 3, 6 1 2010, Pages 231-236
Relationship between temporal sequence of right ventricular deformation and right ventricular performance in patients with corrected tetralogy of Fallot.
van der Hulst AE, Roest AA, Delgado V, Holman ER, de Roos A, Blom NA, Bax JJ
Objective: Right ventricular (RV) dysfunction is common in patients with corrected tetralogy of Fallot (cToF). Abnormalities in the temporal pattern of RV mechanical activation have been observed in patients with cToF, but the relationship with RV performance remains unclear. This study characterises RV performance and the temporal sequence of RV deformation in patients with cToF and healthy controls. Study design: 37 patients with cToF were compared with 18 controls. Using two-dimensional speck...
Abstract
Cited 13 times since 2010 (0.9 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 22, Issue 6, 6 1 2010, Pages 677-683
Upgrading to biventricular pacing guided by pressure-volume loop analysis during implantation.
Delnoy PP, Ottervanger JP, Vos DH, Elvan A, Misier AR, Beukema WP, Steendijk P, van Hemel NM
Introduction: cardiac resynchronization therapy (CRT) may improve prognosis in patients with chronic right ventricular (RV) pacing, and optimal lead position can decrease nonresponders. We evaluated the clinical and echocardiographic response to CRT in patients with previous chronic RV pacing, using pressure-volume loop analyses to determine the optimal left ventricular (LV) lead position during implantation. Methods and results: In this single-blinded, randomized, controlled crossover study, 40...
Abstract
Cited 19 times since 2010 (1.3 per year)
source: EuropePMC
Current medical research and opinion,
Volume 27, Issue 1, 6 1 2010, Pages 141-150
Rationale and design of dal-VESSEL: a study to assess the safety and efficacy of dalcetrapib on endothelial function using brachial artery flow-mediated vasodilatation.
Kastelein JJ, Duivenvoorden R, Deanfield J, de Groot E, Jukema JW, Kaski JC, Münzel T, Taddei S, Lehnert V, Burgess T, Kallend D, Lüscher TF
Objective: Dalcetrapib increases high-density lipoprotein cholesterol (HDL-C) levels through effects on cholesteryl ester transfer protein (CETP). As part of the dalcetrapib dal-HEART clinical trial programme, the efficacy and safety of dalcetrapib is assessed in coronary heart disease (CHD) patients in the dal-VESSEL study (ClinicalTrials.gov identifier: NCT00655538), the design and methods of which are presented here. RESEARCH DESIGN AND STUDY METHOD: Men and women with CHD or CHD risk equival...
Abstract
Cited 117 times since 2010 (8.2 per year)
source: Scopus
American heart journal,
Volume 160, Issue 6, 1 1 2010, Pages 1113-1120
Impact of left ventricular systolic function on clinical and echocardiographic outcomes following transcatheter aortic valve implantation for severe aortic stenosis.
Ewe SH, Ajmone Marsan N, Pepi M, Delgado V, Tamborini G, Muratori M, Ng AC, van der Kley F, de Weger A, Schalij MJ, Fusari M, Biglioli P, Bax JJ
Background: This study aimed to evaluate the impact of baseline left ventricular (LV) systolic function on clinical and echocardiographic outcomes following transcatheter aortic valve implantation (TAVI). Survival of patients undergoing TAVI was also compared with that of a population undergoing surgical aortic valve replacement. Methods: One hundred forty-seven consecutive patients (mean age=80±7 years) undergoing TAVI in 2 centers were included. Mean follow-up period was 9.1±5.1 months. Result...
Abstract
Cited 30 times since 2010 (2.1 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 90, Issue 6, 1 1 2010, Pages 1922-1929
Mitral valve morphology assessment: three-dimensional transesophageal echocardiography versus computed tomography.
Shanks M, Delgado V, Ng AC, van der Kley F, Schuijf JD, Boersma E, van de Veire NR, Nucifora G, Bertini M, de Roos A, Kroft L, Schalij MJ, Bax JJ
Background: Advances in the minimally invasive mitral valve repair techniques increase the demands on accurate and reliable morphologic assessment of the mitral valve using three-dimensional imaging modalities. The present study compared mitral valve geometry measurements obtained by three-dimensional transesophageal echocardiography (TEE) to those obtained with multidetector row computed tomography (MDCT) used as a standard reference. Methods: Clinical preoperative MDCT and intraoperative three...
Abstract
Cited 51 times since 2010 (3.6 per year)
source: EuropePMC
AJR. American journal of roentgenology,
Volume 195, Issue 6, 1 1 2010, Pages 1299-1305
Assessment of Agatston coronary artery calcium score using contrast-enhanced CT coronary angiography.
van der Bijl N, Joemai RM, Geleijns J, Bax JJ, Schuijf JD, de Roos A, Kroft LJ
Objective: The purpose of this article is to evaluate to what extent Agatston scores may be derived from CT coronary angiography (CTA) examinations, compared with traditional unenhanced CT calcium scores. Materials and methods: Fifty patients with a CT calcium score-Agatston score of zero and 50 patients with a CT calcium score-Agatston score of 1 or greater whose CT calcium scores had been calculated and who had undergone CTA using volumetric 320-MDCT were included. Agatston scores were obtaine...
Abstract
Cited 17 times since 2010 (1.2 per year)
source: EuropePMC
Human mutation,
Volume 31, Issue 12, 1 1 2010, Pages E1915-27
The clinical spectrum of missense mutations of the first aspartic acid of cbEGF-like domains in fibrillin-1 including a recessive family.
Hilhorst-Hofstee Y, Rijlaarsdam ME, Scholte AJ, Swart-van den Berg M, Versteegh MI, van der Schoot-van Velzen I, Schäbitz HJ, Bijlsma EK, Baars MJ, Kerstjens-Frederikse WS, Giltay JC, Hamel BC, Breuning MH, Pals G
Marfan syndrome (MFS) is a dominant disorder with a recognizable phenotype. In most patients with the classical phenotype mutations are found in the fibrillin-1 gene (FBN1) on chromosome 15q21. It is thought that most mutations act in a dominant negative way or through haploinsufficiency. In 9 index cases referred for MFS we detected heterozygous missense mutations in FBN1 predicted to substitute the first aspartic acid of different calcium-binding Epidermal Growth Factor-like (cbEGF) fibrillin-...
Abstract
Cited 16 times since 2010 (1.1 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 90, Issue 6, 1 1 2010, Pages 1913-1920
Clinical and functional effects of restrictive mitral annuloplasty at midterm follow-up in heart failure patients.
ten Brinke EA, Klautz RJ, Tulner SA, Verwey HF, Bax JJ, Delgado V, Holman ER, Schalij MJ, van der Wall EE, Braun J, Versteegh MI, Dion RA, Steendijk P
Background: Restrictive mitral annuloplasty (RMA) is increasingly applied to treat functional mitral regurgitation in heart failure patients. Previous studies indicated beneficial clinical effects with low recurrence rates. However, the underlying pathophysiology is complex and outcome in terms of left ventricular function is not well known. We investigated chronic effects of RMA on ventricular function in relation to clinical outcome. Methods: Heart failure patients (n = 11) with severe mitral...
Abstract
Cited 7 times since 2010 (0.5 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 40, Issue 6, 1 1 2010, Pages 696-707
Assessing the quality of surgical care in vascular surgery; moving from outcome towards structural and process measures.
Ploeg AJ, Flu HC, Lardenoye JH, Hamming JF, Breslau PJ
Objectives: This study presents a review of studies reporting on quality of care in vascular surgery. The aim of this study was to provide insight in quality improvement initiatives in vascular surgery. Design: Original data were collected from MEDLINE and EMBASE databases. Inclusion criteria were: description of one of the three factors of quality of care, e.g. process, outcome or structure and prospectively described. All articles identified were ascribed to a domain of quality of care. Result...
Abstract
Cited 129 times since 2010 (9 per year)
source: EuropePMC
Circulation,
Volume 122, Issue 24, 29 5 2010, Pages 2538-2544
Myocardial steatosis and biventricular strain and strain rate imaging in patients with type 2 diabetes mellitus.
Ng AC, Delgado V, Bertini M, van der Meer RW, Rijzewijk LJ, Hooi Ewe S, Siebelink HM, Smit JW, Diamant M, Romijn JA, de Roos A, Leung DY, Lamb HJ, Bax JJ
Background: Magnetic resonance spectroscopy can quantify myocardial triglyceride content in type 2 diabetic patients. Its relation to alterations in left (LV) and right (RV) ventricular myocardial functions is unknown. Methods and results: A total of 42 men with type 2 diabetes mellitus were recruited. Exclusion criteria included hemoglobin A(1c) >8.5, known cardiovascular disease, diabetes-related complications, or blood pressure >150/85 mm Hg. Myocardial ischemia was excluded by a negati...
Abstract
Cited 16 times since 2010 (1.1 per year)
source: EuropePMC
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology,
Volume 12, Issue 2, 24 4 2010, Pages 148-155
Subclinical left ventricular dysfunction and coronary atherosclerosis in asymptomatic patients with type 2 diabetes.
Scholte AJ, Nucifora G, Delgado V, Djaberi R, Boogers MJ, Schuijf JD, Kharagjitsingh AV, Jukema JW, van der Wall EE, Kroft LJ, de Roos A, Bax JJ
Aims: The aim of the present study was to evaluate whether subclinical left ventricular (LV) systolic dysfunction is independently related to subclinical coronary atherosclerosis in type 2 diabetic patients and if it could provide incremental information over baseline characteristics to identify high-risk patients. Methods and results: A total of 234 asymptomatic, type 2 diabetic patients without overt LV systolic dysfunction underwent coronary artery calcium (CAC) scoring and two-dimensional ec...
Abstract
Cited 42 times since 2010 (2.9 per year)
source: EuropePMC
Annals of surgical oncology,
Volume 18, Issue 4, 16 3 2010, Pages 1006-1014
Clinical translation of ex vivo sentinel lymph node mapping for colorectal cancer using invisible near-infrared fluorescence light.
Hutteman M, Choi HS, Mieog JS, van der Vorst JR, Ashitate Y, Kuppen PJ, van Groningen MC, Löwik CW, Smit VT, van de Velde CJ, Frangioni JV, Vahrmeijer AL
Background: Sentinel lymph node (SLN) mapping in colorectal cancer may have prognostic and therapeutic significance; however, currently available techniques are not optimal. We hypothesized that the combination of invisible near-infrared (NIR) fluorescent light and ex vivo injection could solve remaining problems of SLN mapping in colorectal cancer. Methods: The FLARE imaging system was used for real-time identification of SLNs after injection of the NIR lymphatic tracer HSA800 in the colon and...
Abstract
Cited 32 times since 2010 (2.2 per year)
source: EuropePMC
Atherosclerosis,
Volume 214, Issue 2, 13 2 2010, Pages 295-300
Atorvastatin inhibits plaque development and adventitial neovascularization in ApoE deficient mice independent of plasma cholesterol levels.
Bot I, Jukema JW, Lankhuizen IM, van Berkel TJ, Biessen EA
Excessive adventitial neovascularization is one of the hallmarks of atherosclerotic plaque progression and is associated with an increased plaque burden by facilitating leukocyte influx and perivascular inflammation. Statins act atheroprotective by reducing plasma cholesterol levels and by quenching inflammation, but recent studies suggest that they may also affect neovascularization. In this study, we aimed to investigate this notion in apoE(-/-) mice. Advanced carotid artery lesions were induc...
Abstract
Cited 385 times since 2010 (26.8 per year)
source: EuropePMC
Circulation. Heart failure,
Volume 4, Issue 1, 12 2 2010, Pages 44-52
Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction.
Westermann D, Lindner D, Kasner M, Zietsch C, Savvatis K, Escher F, von Schlippenbach J, Skurk C, Steendijk P, Riad A, Poller W, Schultheiss HP, Tschöpe C
Background: The pathophysiology of heart failure with normal ejection fraction (HFNEF) is still under discussion. Here we report the influence of cardiac inflammation on extracellular matrix (ECM) remodeling in patients with HFNEF. Methods and results: We investigated left ventricular systolic and diastolic function in 20 patients with HFNEF and 8 control patients by conductance catheter methods and echocardiography. Endomyocardial biopsy samples were also obtained, and ECM proteins as well as c...
Abstract
Cited 18 times since 2010 (1.3 per year)
source: EuropePMC
BMC musculoskeletal disorders,
Volume 11, 12 2 2010, Pages 263
Functional treatment versus plaster for simple elbow dislocations (FuncSiE): a randomized trial.
de Haan J, den Hartog D, Tuinebreijer WE, Iordens GI, Breederveld RS, Bronkhorst MW, Bruijninckx MM, De Vries MR, Dwars BJ, Eygendaal D, Haverlag R, Meylaerts SA, Mulder JW, Ponsen KJ, Roerdink WH, Roukema GR, Schipper IB, Schouten MA, Sintenie JB, Sivro S, Van den Brand JG, Van der Meulen HG, Van Thiel TP, Van Vugt AB, Verleisdonk EJ, Vroemen JP, Waleboer M, Willems WJ, Polinder S, Patka P, van Lieshout EM, Schep NW
Background: Elbow dislocations can be classified as simple or complex. Simple dislocations are characterized by the absence of fractures, while complex dislocations are associated with fractures. After reduction of a simple dislocation, treatment options include immobilization in a static plaster for different periods of time or so-called functional treatment. Functional treatment is characterized by early active motion within the limits of pain with or without the use of a sling or hinged brace...
Abstract
Cited 2 times since 2010 (0.1 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 97, Issue 1, 11 2 2010, Pages 1-3
Can cardiac [123I]m-iodobenzylguanidine imaging be used for risk stratification of patients with acute myocardial infarction?
Boogers MJ, Bax JJ
Abstract
Cited 13 times since 2010 (0.9 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 97, Issue 2, 8 2 2010, Pages 143-150
Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies.
Pons D, Trompet S, de Craen AJ, Thijssen PE, Quax PH, de Vries MR, Wierda RJ, van den Elsen PJ, Monraats PS, Ewing MM, Heijmans BT, Slagboom PE, Zwinderman AH, Doevendans PA, Tio RA, de Winter RJ, de Maat MP, Iakoubova OA, Sattar N, Shepherd J, Westendorp RG, Jukema JW, PROSPER study group, WOSCOPS study group, GENDER study group
Aims: This study was designed to investigate the counterbalancing influence of genetic variation in the promoter of the gene encoding P300/CBP associated factor (PCAF), a lysine acetyltransferase (KAT), on coronary heart disease (CHD) and mortality. Methods and results: The association of genetic variation in the PCAF-gene with CHD, restenosis and mortality was investigated in three large cohorts. The results were combined to examine overall effects on CHD mortality and on restenosis risk. Compa...
Abstract
