Publications
Below you can find a list of our published research.
Op korte termijn komt deze Hart Long Centrum website te vervallen. Alle informatie kunt u vanaf heden vinden op https://www.lumc.nl/patientenzorg/specialistische-centra/hart-long-centrum/voor-patienten/
Below you can find a list of our published research.
7971 results
Cited 11 times since 2020 (2.4 per year) source: EuropePMC
Journal of orthopaedic trauma, Volume 34 Suppl 3, 1 1 2020, Pages S9-S14 Arthroplasty Versus Internal Fixation for the Treatment of Undisplaced Femoral Neck Fractures: A Retrospective Cohort Study. Afaq S, OʼHara NN, Schemitsch EH, Bzovsky S, Sprague S, Poolman RW, Frihagen F, Heels-Ansdell D, Bhandari M, Swiontkowski M, Slobogean GP, FAITH Investigators, HEALTH Investigators
Objective: To compare the 24-month risk of mortality between arthroplasty and internal fixation for undisplaced femoral neck fractures (FNFs). Design: Retrospective cohort study. Setting: Secondary data analysis of 2 multinational randomized controlled trials. Participants: Patients aged 50 years or older with a FNF. Intervention: Arthroplasty (n = 1441), including total hip arthroplasty and hemiarthroplasty, performed for a displaced FNF versus internal fixation (n = 734), including sliding hip... Abstract
Cited 26 times since 2020 (5.7 per year) source: EuropePMC
Molecular oncology, Volume 15, Issue 1, 31 5 2020, Pages 57-66 Comparison of variant allele frequency and number of mutant molecules as units of measurement for circulating tumor DNA. Bos MK, Nasserinejad K, Jansen MPHM, Angus L, Atmodimedjo PN, de Jonge E, Dinjens WNM, van Schaik RHN, Del Re M, Dubbink HJ, Sleijfer S, Martens JWM
Quantification of tumor-specific variants (TSVs) in cell-free DNA is rapidly evolving as a prognostic and predictive tool in patients with cancer. Currently, both variant allele frequency (VAF) and number of mutant molecules per mL plasma are used as units of measurement to report those TSVs. However, it is unknown to what extent both units of measurement agree and what are the factors underlying an existing disagreement. To study the agreement between VAF and mutant molecules in current clinica... Abstract
Cited 10 times since 2020 (2.2 per year) source: EuropePMC
Pediatric nephrology (Berlin, Germany), Volume 36, Issue 5, 31 5 2020, Pages 1195-1205 Predictors of poor kidney outcome in children with C3 glomerulopathy. Pınarbaşı AS, Dursun I, Gokce I, Çomak E, Saygılı S, Bayram MT, Donmez O, Melek E, Tekcan D, Çiçek N, Yılmaz D, Tabel Y, Yıldırım ZY, Bahat E, Koyun M, Soylu A, Canpolat N, Aksu B, Çelakıl ME, Taşdemir M, Benzer M, Özçelik G, Bakkaloğlu SA, Düşünsel R
Background: C3 glomerulopathy (C3G) is characterized by heterogeneous clinical presentation, outcome, and predominant C3 accumulation in glomeruli without significant IgG. There is scarce outcome data regarding childhood C3G. We describe clinical and pathological features, treatment and outcomes, and risk factors for progression to chronic kidney disease stage 5 (CKD5) in the largest pediatric series with biopsy-proven C3G. Methods: Sixty pediatric patients with C3G from 21 referral centers in T... Abstract
Cited 9 times since 2020 (2 per year) source: EuropePMC
Cancers, Volume 12, Issue 11, 29 5 2020, Pages E3179 Plasma Predictive Features in Treating EGFR-Mutated Non-Small Cell Lung Cancer. Steendam CMJ, Veerman GDM, Pruis MA, Atmodimedjo P, Paats MS, van der Leest C, von der Thüsen JH, Yick DCY, Oomen-de Hoop E, Koolen SLW, Dinjens WNM, van Schaik RHN, Mathijssen RHJ, Aerts JGJV, Dubbink HJ, Dingemans AC
Although epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are the preferred treatment for patients with EGFR-mutated non-small cell lung cancer (NSCLC), not all patients benefit. We therefore explored the impact of the presence of mutations found in cell-free DNA (cfDNA) and TKI plasma concentrations during treatment on progression-free survival (PFS). In the prospective START-TKI study blood samples from 41 patients with EGFR-mutated NSCLC treated with EGFR-TKIs were av... Abstract
Cited 9 times since 2020 (2 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 14, Issue 4, 28 4 2020, Pages 756-765 Insufficient Mitral Leaflet Remodeling in Relation to Annular Dilation and Risk of Residual Mitral Regurgitation After MitraClip Implantation. Hirasawa K, Namazi F, Milhorini Pio S, Vo NM, Ajmone Marsan N, Bax JJ, Delgado V
Objectives: The purpose of this study was to determine whether the mitral valve (MV) total leaflet area (TLA)-to-mitral annular area (MAA) (TLA/MAA) ratio measured using 3-dimensional (3D) transesophageal echocardiography (TEE) was associated with residual mitral regurgitation (MR) after MitraClip implantation in patients with secondary MR. Background: The factors influencing the results of MitraClip implantation for secondary MR are controversial. This study hypothesized that insufficient remod... Abstract
Cited 18 times since 2020 (3.9 per year) source: EuropePMC
JACC. Clinical electrophysiology, Volume 7, Issue 2, 28 4 2020, Pages 197-205 Mini-, Micro-, and Conventional Electrodes: An in Vivo Electrophysiology and Ex Vivo Histology Head-to-Head Comparison. Glashan CA, Beukers HKC, Tofig BJ, Tao Q, Blom S, Mertens B, Kristiansen SB, Zeppenfeld K
Objectives: This study sought to assess the relative effect of catheter, tissue, and catheter-tissue parameters, on the ability to determine the amount of viable myocardium in vivo. Background: Although multiple variables impact bipolar voltages (BVs), electrode size, interelectrode spacing, and directional dependency are of particular interest with the development of catheters incorporating mini and microelectrodes. Methods: Nine swine with early reperfusion myocardial infarctions were mapped u... Abstract
Cited 4 times since 2020 (0.9 per year) source: EuropePMC
Journal of gastrointestinal and liver diseases : JGLD, Volume 29, Issue 4, 27 4 2020, Pages 617-622 Evaluation of the Association between Programmed Cell Death-1 Gene Polymorphisms and Hepatocellular Carcinoma Susceptibility in Turkish Subjects. A Pilot Study. Demirci AF, Demirtas CO, Eren F, Yilmaz D, Keklikkiran C, Ozdogan OC, Gunduz F
Background and aims: Programmed cell death-1 (PD-1) has a vital role in regulating T-cell function, and immune escape mechanism of cancer cells. It was shown that there could be a relationship between single nucleotide polymorphisms (SNPs) in the PD-1 gene and susceptibility to hepatocellular carcinoma (HCC) based on various studies. We aimed to investigate the role of three SNPs within the PD-1 gene in susceptibility to HCC in the Turkish population. Methods: Single nucleotide polymorphisms of... Abstract
Cited 17 times since 2020 (3.7 per year) source: EuropePMC
Cardiovascular drugs and therapy, Volume 36, Issue 4, 21 3 2020, Pages 739-748 The Use of Angiotensin II for the Treatment of Post-cardiopulmonary Bypass Vasoplegia. Papazisi O, Palmen M, Danser AHJ
Purpose: Vasoplegia is a common complication after cardiac surgery and is related to the use of cardiopulmonary bypass (CPB). Despite its association with increased morbidity and mortality, no consensus exists in terms of its treatment. In December 2017, angiotensin II (AII) was approved by the Food and Drug Administration (FDA) for use in vasodilatory shock; however, except for the ATHOS-3 trial, its use in vasoplegic patients that underwent cardiac surgery on CPB has mainly been reported in ca... Abstract
Cited 2 times since 2020 (0.4 per year) source: EuropePMC
Journal of cardiac surgery, Volume 35, Issue 12, 21 3 2020, Pages 3477-3485 Prosthesis-patient mismatch after mitral valve replacement: A pooled meta-analysis of Kaplan-Meier-derived individual patient data. Tomšič A, Arabkhani B, Schoones JW, Etnel JRG, Marsan NA, Klautz RJM, Palmen M
Objective: The hemodynamic effect and early and late survival impact of prosthesis-patient mismatch (PPM) after mitral valve replacement remains insufficiently explored. Methods: Pubmed, Embase, Web of Science, and Cochrane Library databases were searched for English language original publications. The search yielded 791 potentially relevant studies. The final review and analysis included 19 studies compromising 11,675 patients. Results: Prosthetic effective orifice area was calculated with the... Abstract
Cited 6 times since 2020 (1.3 per year) source: EuropePMC
International journal of cardiology, Volume 326, 21 3 2020, Pages 88-91 The aortic root in repaired tetralogy of Fallot: Serial measurements and impact of losartan treatment. Woudstra OI, Ghanam A, Vliegen HW, van Dijk APJ, van Melle JP, Groenink M, Meijboom FJ, Post MC, Mulder BJM, Bouma BJ, Bokma JP
Background: Aortic root dilatation is common in adults with repaired tetralogy of Fallot (rTOF) and might lead to aortic dissection. However, little is known on progression of aortic dilatation and the effect of pharmaceutical treatment. This study aims to determine factors associated with aortic growth and investigate effects of losartan. Methods and results: We performed a prespecified analysis from the 1:1 randomized, double-blind REDEFINE trial. Aortic root diameters were measured at baselin... Abstract
Cited 5 times since 2020 (1.1 per year) source: EuropePMC
The Annals of pharmacotherapy, Volume 55, Issue 6, 17 3 2020, Pages 697-704 Impact of Extended-Interval Versus Standard Dosing of Zoledronic Acid on Skeletal Events in Non-Small-Cell Lung Cancer and Small-Cell Lung Cancer Patients With Bone Metastases. Tam AH, Schepers AJ, Qin A, Nachar VR
Background: Zoledronic acid every 4 weeks (Q4wk) reduces the incidence of skeletal-related events (SREs) in patients with metastatic lung cancer. Lung cancer patients were excluded from extended-interval dosing trials (every 12 weeks [Q12wk]) that demonstrated noninferiority of the 2 dosing schemes. To date, the optimal dosing of zoledronic acid in metastatic lung cancer remains unknown. Objective: To determine whether zoledronic acid dosed Q12wk is similar to Q4wk dosing for prevention of SRE i... Abstract
Cited 2 times since 2020 (0.4 per year) source: EuropePMC
European heart journal. Case reports, Volume 4, Issue 5, 15 3 2020, Pages 1-3 Pulmonary hypertension causing left main coronary artery compression. Verheijen DBH, Meijer FMM, Kiès P, Egorova AD
Cited 19 times since 2020 (4.1 per year) source: EuropePMC
International journal of cancer, Volume 148, Issue 4, 13 2 2020, Pages 981-987 The clonal relation of primary upper urinary tract urothelial carcinoma and paired urothelial carcinoma of the bladder. van Doeveren T, Nakauma-Gonzalez JA, Nakauma-Gonzalez JA, Mason AS, van Leenders GJLH, Zuiverloon TCM, Zwarthoff EC, Meijssen IC, van der Made AC, van der Heijden AG, Hendricksen K, van Rhijn BWG, Voskuilen CS, van Riet J, Dinjens WNM, Dubbink HJ, van de Werken HJG, Boormans JL
The risk of developing urothelial carcinoma of the bladder (UCB) in patients treated by radical nephroureterectomy (RNU) for an upper urinary tract urothelial carcinoma (UTUC) is 22% to 47% in the 2 years after surgery. Subject of debate remains whether UTUC and the subsequent UCB are clonally related or represent separate origins. To investigate the clonal relationship between both entities, we performed targeted DNA sequencing of a panel of 41 genes on matched normal and tumor tissue of 15 pri... Abstract
Cited 7 times since 2020 (1.5 per year) source: EuropePMC
Peptides, Volume 135, 13 2 2020, Pages 170424 Interplay of circulating leptin and obesity in cognition and cerebral volumes in older adults. Zonneveld MH, Noordam R, van der Grond J, van Heemst D, Mooijaart SP, Sabayan B, Jukema JW, Trompet S
We aimed to investigate whether circulating leptin and body mass index (BMI) associate independently with cognitive function (decline) and brain volumes using magnetic resonance imaging (MRI) in older individuals at risk of cardiovascular disease. We studied the cross-sectional and longitudinal associations in participants enrolled in the PROSPER study (Prospective Study of Pravastatin in the Elderly at Risk). Cognitive function was tested at baseline and repeated during a mean follow-up time of... Abstract
Cited 110 times since 2020 (23.7 per year) source: EuropePMC
PLoS genetics, Volume 16, Issue 10, 12 2 2020, Pages e1008718 Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. Vogelezang S, Bradfield JP, Ahluwalia TS, Curtin JA, Lakka TA, Grarup N, Scholz M, van der Most PJ, Monnereau C, Stergiakouli E, Heiskala A, Horikoshi M, Fedko IO, Vilor-Tejedor N, Cousminer DL, Standl M, Wang CA, Viikari J, Geller F, Íñiguez C, Pitkänen N, Chesi A, Bacelis J, Yengo L, Torrent M, Ntalla I, Helgeland Ø, Selzam S, Vonk JM, Zafarmand MH, Heude B, Farooqi IS, Alyass A, Beaumont RN, Have CT, Rzehak P, Bilbao JR, Schnurr TM, Barroso I, Bønnelykke K, Beilin LJ, Carstensen L, Charles MA, Chawes B, Clément K, Closa-Monasterolo R, Custovic A, Eriksson JG, Escribano J, Groen-Blokhuis M, Grote V, Gruszfeld D, Hakonarson H, Hansen T, Hattersley AT, Hollensted M, Hottenga JJ, Hyppönen E, Johansson S, Joro R, Kähönen M, Karhunen V, Kiess W, Knight BA, Koletzko B, Kühnapfel A, Landgraf K, Langhendries JP, Lehtimäki T, Leinonen JT, Li A, Lindi V, Lowry E, Bustamante M, Medina-Gomez C, Melbye M, Michaelsen KF, Morgen CS, Mori TA, Nielsen TRH, Niinikoski H, Oldehinkel AJ, Pahkala K, Panoutsopoulou K, Pedersen O
The genetic background of childhood body mass index (BMI), and the extent to which the well-known associations of childhood BMI with adult diseases are explained by shared genetic factors, are largely unknown. We performed a genome-wide association study meta-analysis of BMI in 61,111 children aged between 2 and 10 years. Twenty-five independent loci reached genome-wide significance in the combined discovery and replication analyses. Two of these, located near NEDD4L and SLC45A3, have not previo... Abstract
Cited 37 times since 2020 (8 per year) source: EuropePMC
Biology & philosophy, Volume 35, Issue 5, 11 2 2020, Pages 55 The zone of latent solutions and its relevance to understanding ape cultures. Tennie C, Bandini E, van Schaik CP, Hopper LM
The zone of latent solutions (ZLS) hypothesis provides an alternative approach to explaining cultural patterns in primates and many other animals. According to the ZLS hypothesis, non-human great ape (henceforth: ape) cultures consist largely or solely of latent solutions. The current competing (and predominant) hypothesis for ape culture argues instead that at least some of their behavioural or artefact forms are copied through specific social learning mechanisms ("copying social learning... Abstract
Cited 11 times since 2020 (2.4 per year) source: EuropePMC
BMC sports science, medicine & rehabilitation, Volume 12, 9 2 2020, Pages 63 The effects of exergaming on pain, postural control, technology acceptance and flow experience in older people with chronic musculoskeletal pain: a randomised controlled trial. Ditchburn JL, van Schaik P, Dixon J, MacSween A, Martin D
Background: Older people with chronic musculoskeletal pain are at risk of falls. This study aimed to investigate the effects of exergaming on pain and postural control in older people with chronic musculoskeletal pain. Secondary outcomes were technology acceptance, flow experience, perceived physical exertion, expended mental effort and heart rate. Methods: Fifty four older adults (age: 71 ± 5 years) with chronic musculoskeletal pain were randomised into 2 groups. Group 1 received exergaming tra... Abstract
Cited 1 times since 2020 (0.2 per year) source: EuropePMC
Appetite, Volume 157, 8 2 2020, Pages 104987 Using behavioural insights to reduce sugar in primary school children's packed lunches in derby; A cluster randomised controlled trial. Bunten A, Porter L, Burgess-Allen J, Howell-Jones R, Jackson J, Ward D, Staples V, Staples P, Rowthorn H, Saei A, van Schaik P, Tydeman E, Blair P, Hugueniot O, Gold N, Chadborn T
Children's packed lunches contain more sugar than school-provided meals. Interventions to improve the provision of healthier packed lunches have modest effects on lunch contents. This cluster randomised controlled trial tested an intervention to encourage healthier provision of packed lunches by parents of primary school children in Derby. Schools were randomised to intervention (n = 8) or control (n = 9) using blocked random allocation. In the intervention group, parents of children who br... Abstract
Nature communications, Volume 11, Issue 1, 8 2 2020, Pages 5141 Author Correction: Straightforward preparation of supramolecular Janus nanorods by hydrogen bonding of end-functionalized polymers. Han S, Pensec S, Yilmaz D, Lorthioir C, Jestin J, Guigner JM, Niepceron F, Rieger J, Stoffelbach F, Nicol E, Colombani O, Bouteiller L
An amendment to this paper has been published and can be accessed via a link at the top of the paper. Abstract
Cited 9 times since 2020 (1.9 per year) source: EuropePMC
Proceedings. Mathematical, physical, and engineering sciences, Volume 476, Issue 2242, 7 1 2020, Pages 20200731 Correction to 'Wald's martingale and the conditional distributions of absorption time in the Moran process'. Monk T, van Schaik A
[This corrects the article DOI: 10.1098/rspa.2020.0135.]. Abstract