6205 results
Cited 14 times since 2014 (1.2 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 30, Issue 4, 4 1 2014, Pages 713-720
Impact of right ventricular dyssynchrony on left ventricular performance in patients with pulmonary hypertension.
Haeck ML, Höke U, Marsan NA, Holman ER, Wolterbeek R, Bax JJ, Schalij MJ, Vliegen HW, Delgado V
Pulmonary hypertension has been associated with right ventricular (RV) dyssynchrony which may induce left ventricular (LV) dysfunction and dyssynchrony through ventricular interdependence. The present study evaluated the influence of RV dyssynchrony on LV performance in patients with pulmonary hypertension. One hundred and seven patients with pulmonary hypertension (age 63 ± 14 years, systolic pulmonary arterial pressure 60 ± 19 mmHg) and LV ejection fraction (EF) >35% were evaluated. Ventric...
Abstract
Cited 1 times since 2014 (0.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 22, Issue 2, 1 1 2014, Pages 77-79
ST-segment elevation associated with allergic reaction to echocardiographic contrast agent administration.
van Ginkel A, Sorgdrager B, de Graaf MA, Karalis I, Ajmone Marsan N
We report a case of an allergic reaction after the administration of an echocardiographic contrast agent which resulted in ST-segment elevation. Hypersensitivity and allergic reactions are known causes of acute cardiovascular events. However, only limited reports are available which suggest the exact mechanism of the occurrence of angina or myocardial infarction during severe allergic reactions. In our case, through invasive imaging (coronary angiography and IVUS) we have shown for the first tim...
Abstract
Cited 16 times since 2014 (1.4 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 22, Issue 2, 1 1 2014, Pages 64-69
Antithrombotic therapy in patients undergoing TAVI: an overview of Dutch hospitals.
Nijenhuis VJ, Stella PR, Baan J, Brueren BR, de Jaegere PP, den Heijer P, Hofma SH, Kievit P, Slagboom T, van den Heuvel AF, van der Kley F, van Garsse L, van Houwelingen KG, Van't Hof AW, Ten Berg JM
Purpose: To assess current antithrombotic treatment strategies in the Netherlands in patients undergoing transcatheter aortic valve implantation (TAVI). Methods: For every Dutch hospital performing TAVI (n = 14) an interventional cardiologist experienced in performing TAVI was interviewed concerning heparin, aspirin, thienopyridine and oral anticoagulation treatment in patients undergoing TAVI. Results: The response rate was 100 %. In every centre, a protocol for antithrombotic treatment after T...
Abstract
Cited 1 times since 2014 (0.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 63, Issue 6, 1 1 2014, Pages 570-602
Highlights of the year in JACC 2013.
DeMaria AN, Adler ED, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall JL, Hlatky MA, Lew WY, Lima JA, Mahmud E, Maisel AS, Narayan SM, Nissen SE, Sahn DJ, Tsimikas S
Abstract
Cited 133 times since 2014 (11.8 per year)
source: EuropePMC
European heart journal,
Volume 35, Issue 22, 31 5 2014, Pages 1466-1478
The atrial fibrillation ablation pilot study: a European Survey on Methodology and results of catheter ablation for atrial fibrillation conducted by the European Heart Rhythm Association.
Arbelo E, Brugada J, Hindricks G, Maggioni AP, Tavazzi L, Vardas P, Laroche C, Anselme F, Inama G, Jais P, Kalarus Z, Kautzner J, Lewalter T, Mairesse GH, Perez-Villacastin J, Riahi S, Taborsky M, Theodorakis G, Trines SA, Atrial Fibrillation Ablation Pilot Study Investigators
Aims: The Atrial Fibrillation Ablation Pilot Study is a prospective registry designed to describe the clinical epidemiology of patients undergoing an atrial fibrillation (AFib) ablation, and the diagnostic/therapeutic processes applied across Europe. The aims of the 1-year follow-up were to analyse how centres assess in routine clinical practice the success of the procedure and to evaluate the success rate and long-term safety/complications. Methods and results: Seventy-two centres in 10 Europea...
Abstract
Cited 5 times since 2014 (0.4 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 30, Issue 3, 31 5 2014, Pages 583-589
Effect of intramyocardial bone marrow-derived mononuclear cell injection on cardiac sympathetic innervation in patients with chronic myocardial ischemia.
van Ramshorst J, Beeres SL, Rodrigo SF, Dibbets-Schneider P, Scholte AJ, Fibbe WE, Zwaginga JJ, Schalij MJ, Bax JJ, Atsma DE
Intramyocardial bone marrow cell injection has been associated with improvements in myocardial perfusion and left ventricular function. The current substudy of a randomized, placebo-controlled, double-blinded study, investigated the effect of intramyocardial bone marrow cell injection on myocardial sympathetic innervation in patients with chronic myocardial ischemia. In a total of 16 patients (64 ± 8 years, 13 men), early and late iodine-123 metaiodobenzylguanidine (MIBG) imaging was performed b...
Abstract
Cited 100 times since 2014 (8.8 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 63, Issue 12, 30 5 2014, Pages 1200-1210
Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese.
Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dörr M, Ozaki K, Smith AV, Müller-Nurasyid M, Walter S, Agarwal SK, Bis JC, Brody JA, Chen LY, Everett BM, Ford I, Franco OH, Harris TB, Hofman A, Kääb S, Mahida S, Kathiresan S, Kubo M, Launer LJ, MacFarlane PW, Magnani JW, McKnight B, McManus DD, Peters A, Psaty BM, Rose LM, Rotter JI, Silbernagel G, Smith JD, Sotoodehnia N, Stott DJ, Taylor KD, Tomaschitz A, Tsunoda T, Uitterlinden AG, Van Wagoner DR, Völker U, Völzke H, Murabito JM, Sinner MF, Gudnason V, Felix SB, März W, Chung M, Albert CM, Stricker BH, Tanaka T, Heckbert SR, Jukema JW, Alonso A, Benjamin EJ, Ellinor PT
Objectives: This study sought to identify nonredundant atrial fibrillation (AF) genetic susceptibility signals and examine their cumulative relations with AF risk. Background: AF-associated loci span broad genomic regions that may contain multiple susceptibility signals. Whether multiple signals exist at AF loci has not been systematically explored. Methods: We performed association testing conditioned on the most significant, independently associated genetic markers at 9 established AF loci usi...
Abstract
Cited 16 times since 2014 (1.4 per year)
source: EuropePMC
Journal of virology,
Volume 88, Issue 8, 29 5 2014, Pages 4595-4599
Novel avian-origin influenza A (H7N9) virus attachment to the respiratory tract of five animal models.
Siegers JY, Short KR, Leijten LM, de Graaf M, Spronken MI, Schrauwen EJ, Marshall N, Lowen AC, Gabriel G, Osterhaus AD, Kuiken T, van Riel D
We determined the pattern of attachment of the avian-origin H7N9 influenza viruses A/Anhui/1/2013 and A/Shanghai/1/2013 to the respiratory tract in ferrets, macaques, mice, pigs, and guinea pigs and compared it to that in humans. The H7N9 attachment pattern in macaques, mice, and to a lesser extent pigs and guinea pigs resembled that in humans more closely than the attachment pattern in ferrets. This information contributes to our knowledge of the different animal models for influenza.
Abstract
Cited 8 times since 2014 (0.7 per year)
source: EuropePMC
PloS one,
Volume 9, Issue 1, 27 4 2014, Pages e86522
Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms.
van den Borne P, van der Laan SW, Bovens SM, Koole D, Kowala MC, Michael LF, Schoneveld AH, van de Weg SM, Velema E, de Vries JP, de Borst GJ, Moll FL, de Kleijn DP, Quax PH, Hoefer IE, Pasterkamp G
Background: Leukotriene B4 (LTB4) has been associated with the initiation and progression of atherosclerosis and abdominal aortic aneurysm (AAA) formation. However, associations of LTB4 levels with tissue characteristics and adverse clinical outcome of advanced atherosclerosis and AAA are scarcely studied. We hypothesized that LTB4 levels are associated with a vulnerable plaque phenotype and adverse clinical outcome. Furthermore, that LTB4 levels are associated with inflammatory AAA and adverse...
Abstract
Cited 54 times since 2014 (4.8 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 148, Issue 4, 25 4 2014, Pages 1583-1590
Ascending aorta dilation in association with bicuspid aortic valve: a maturation defect of the aortic wall.
Grewal N, Gittenberger-de Groot AC, Poelmann RE, Klautz RJ, Lindeman JH, Goumans MJ, Palmen M, Mohamed SA, Sievers HH, Bogers AJ, DeRuiter MC
Objective: Patients with a bicuspid aortic valve have increased susceptibility to the development of ascending aortic dilation and dissection compared with persons with a tricuspid valve. To unravel a possible different mechanism underlying dilation in bicuspidy and tricuspidy, a comparison of the structure of the aortic wall was made. Methods: Ascending aortic wall biopsies were divided into 4 groups: bicuspid (n=36) and tricuspid (n=23) without and with dilation. The expression of vascular smo...
Abstract
Cited 88 times since 2014 (7.8 per year)
source: EuropePMC
Lung cancer (Amsterdam, Netherlands),
Volume 84, Issue 1, 23 4 2014, Pages 86-91
EGFR mutated non-small cell lung cancer patients: more prone to development of bone and brain metastases?
Hendriks LE, Smit EF, Vosse BA, Mellema WW, Heideman DA, Bootsma GP, Westenend M, Pitz C, de Vries GJ, Houben R, Grünberg K, Bendek M, Speel EJ, Dingemans AM
Objectives: Both bone and brain are frequent sites of metastasis in non-small cell lung cancer (NSCLC). Conflicting data exist whether EGFR mutant (+) patients are more prone to develop brain metastases or have a better outcome with brain metastases compared to EGFR/KRAS wildtype (WT) or KRAS+ patients. For bone metastases this has not been studied. Methods: In this retrospective case-control study all EGFR+ (exons 19 and 21) patients diagnosed at two pathology departments were selected (2004/20...
Abstract
Cited 22 times since 2014 (1.9 per year)
source: EuropePMC
Heart rhythm,
Volume 11, Issue 5, 22 4 2014, Pages 806-813
QRS fusion complex analysis using wave interference to predict reverse remodeling during cardiac resynchronization therapy.
Sweeney MO, Hellkamp AS, van Bommel RJ, Schalij MJ, Borleffs CJ, Bax JJ
Background: Biventricular (BV) electrical wavefront fusion can induce improvement in left ventricular (LV) size and function during cardiac resynchronization therapy (CRT). Changes in BV wave propagation sequence and duration register in the QRS complex on the standard electrocardiogram. We developed a wave interference method for the characterization of BV fusion to predict LV reverse remodeling. Objective: To develop a simple electrocardiographic method for predicting reverse remodeling during...
Abstract
Cited 103 times since 2014 (9.1 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 100, Issue 12, 21 3 2014, Pages 960-968
Significant lead-induced tricuspid regurgitation is associated with poor prognosis at long-term follow-up.
Höke U, Auger D, Thijssen J, Wolterbeek R, van der Velde ET, Holman ER, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Background: Although the presence of an RV lead is a potential cause of tricuspid regurgitation (TR), the clinical impact of significant lead-induced TR is unknown. Objective: To evaluate the effect of significant lead-induced TR on cardiac performance and long-term outcome after cardioverter-defibrillator (ICD) or pacemaker implantation. Methods: A retrospective cohort of 239 ICD (n=191) or pacemaker (n=48) recipients (age 60±14 years, 77% male) from a tertiary care university hospital, with an...
Abstract
Cited 27 times since 2014 (2.4 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 148, Issue 4, 15 3 2014, Pages 1490-1497
Exercise capacity in children after total cavopulmonary connection: lateral tunnel versus extracardiac conduit technique.
Bossers SS, Helbing WA, Duppen N, Kuipers IM, Schokking M, Hazekamp MG, Bogers AJ, Ten Harkel AD, Takken T
Objectives: In patients with univentricular heart disease, the total cavopulmonary connection (TCPC) is the preferred treatment. TCPC can be performed using the intra-atrial lateral tunnel (ILT) or extracardiac conduit (ECC) technique. The purpose of the present study was to evaluate exercise capacity in contemporary TCPC patients and compare the results between the 2 techniques. Methods: A total of 101 TCPC patients (ILT, n=42; ECC, n=59; age, 12.2±2.6 years; age at TCPC completion, 3.2±1.1 yea...
Abstract
Cited 73 times since 2014 (6.4 per year)
source: EuropePMC
International journal of epidemiology,
Volume 43, Issue 3, 14 2 2014, Pages 878-886
Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers.
Deelen J, Beekman M, Codd V, Trompet S, Broer L, Hägg S, Fischer K, Thijssen PE, Suchiman HE, Postmus I, Uitterlinden AG, Hofman A, de Craen AJ, Metspalu A, Pedersen NL, van Duijn CM, Jukema JW, Houwing-Duistermaat JJ, Samani NJ, Slagboom PE
Background: Human leukocyte telomere length (LTL) decreases with age and shorter LTL has previously been associated with increased prospective mortality. However, it is not clear whether LTL merely marks the health status of an individual by its association with parameters of immune function, for example, or whether telomere shortening also contributes causally to lifespan variation in humans. Methods: We measured LTL in 870 nonagenarian siblings (mean age 93 years), 1580 of their offspring and...
Abstract
Cited 13 times since 2014 (1.1 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 27, Issue 3, 13 2 2014, Pages 239-248
Association between multilayer left ventricular rotational mechanics and the development of left ventricular remodeling after acute myocardial infarction.
Abate E, Hoogslag GE, Leong DP, Bertini M, Antoni ML, Nucifora G, Joyce E, Holman ER, Siebelink HM, Schalij MJ, Bax JJ, Delgado V, Ajmone Marsan N
Background: The identification of patients at risk for developing left ventricular (LV) remodeling after acute myocardial infarction (AMI) has crucial prognostic implications. The aims of this study were (1) to investigate the relationship between peak subepicardial and subendocardial twist and infarct transmurality, as assessed using contrast-enhanced magnetic resonance imaging, and (2) to evaluate the association between peak subepicardial and subendocardial twist and LV remodeling 6 months af...
Abstract
Cited 6 times since 2014 (0.5 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 59, Issue 5, 11 2 2014, Pages 1315-22.e1
National variation in the utilization of alternative imaging in peripheral arterial disease.
de Vos MS, Hawkins AT, Hevelone ND, Hamming JF, Nguyen LL
Objective: The value and cost-effectiveness of less invasive alternative imaging (AI) modalities (duplex ultrasound scanning, computed tomography angiography, and magnetic resonance angiography) in the care of peripheral arterial disease (PAD) has been reported; however, there is no consensus on their role. We hypothesized that AI utilization is low compared with angiography in the United States and that patient and hospital characteristics are both associated with AI utilization. Methods: The N...
Abstract
Cited 13 times since 2014 (1.1 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 34, Issue 3, 9 2 2014, Pages 594-602
Absence of chemokine (C-x-C motif) ligand 10 diminishes perfusion recovery after local arterial occlusion in mice.
van den Borne P, Haverslag RT, Brandt MM, Cheng C, Duckers HJ, Quax PH, Hoefer IE, Pasterkamp G, de Kleijn DP
Objective: In arteriogenesis, pre-existing anastomoses undergo enlargement to restore blood flow in ischemic tissues. Chemokine (C-X-C motif) ligand 10 (CXCL10) is secreted after Toll-like receptor activation. Toll-like receptors are involved in arteriogenesis; however, the role of CXCL10 is still unclear. In this study, we investigated the role for CXCL10 in a murine hindlimb ischemia model. Approach and results: Unilateral femoral artery ligation was performed in wild-type (WT) and CXCL10(-/-)...
Abstract
Revista espanola de cardiologia (English ed.),
Volume 67, Issue 2, 8 2 2014, Pages 157
Appropriate use criteria for cardiopulmonary exercise testing in patients with cardiac resynchronization devices. Response.
de Riva-Silva M, López-Gil M, Fontenla-Cerezuela A, Arribas-Ynsaurriaga F
Abstract
Cited 25 times since 2014 (2.2 per year)
source: EuropePMC
Human gene therapy,
Volume 25, Issue 1, 7 1 2014, Pages 41-49
Short hairpin RNA gene silencing of prolyl hydroxylase-2 with a minicircle vector improves neovascularization of hindlimb ischemia.
Lijkwan MA, Hellingman AA, Bos EJ, van der Bogt KE, Huang M, Kooreman NG, de Vries MR, Peters HA, Robbins RC, Hamming JF, Quax PH, Wu JC
In this study, we target the hypoxia inducible factor-1 alpha (HIF-1-alpha) pathway by short hairpin RNA interference therapy targeting prolyl hydroxylase-2 (shPHD2). We use the minicircle (MC) vector technology as an alternative for conventional nonviral plasmid (PL) vectors in order to improve neovascularization after unilateral hindlimb ischemia in a murine model. Gene expression and transfection efficiency of MC and PL, both in vitro and in vivo, were assessed using bioluminescence imaging (...
Abstract
