Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6125 results
Cited 9 times since 2022 (3 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 35, Issue 8, 15 3 2022, Pages 791-800.e4 Left Ventricular Global Longitudinal Strain in Patients with Moderate Aortic Stenosis. Stassen J, Pio SM, Ewe SH, Singh GK, Hirasawa K, Butcher SC, Cohen DJ, Généreux P, Leon MB, Marsan NA, Delgado V, Bax JJ
Moderate aortic stenosis (AS) is associated with an increased risk for adverse events. Although reduced left ventricular (LV) global longitudinal strain (GLS) is associated with worse outcomes in patients with severe AS, its prognostic value in patients with moderate AS is unknown. The aim of this study was to investigate the prognostic implications of LV GLS in patients with moderate AS. Methods: LV GLS was evaluated using speckle-tracking echocardiography in patients with moderate AS (aortic v... Abstract
Medical sciences (Basel, Switzerland), Volume 10, Issue 1, 15 3 2022, Pages 19 Parathyroid Allotransplantation: A Systematic Review. Zhang JLH, Appelman-Dijkstra NM, Schepers A
Background: To date, there is no satisfactory treatment for patients with calcium and vitamin D supplementation refractive hypoparathyroidism. Parathyroid allotransplantation by design is a one-time cure through its restoration of the parathyroid function and, therefore, could be the solution. A systematic literature review is conducted in the present paper, with the aim of outlining the possibilities of parathyroid allotransplantation and to calculate its efficacy. Additionally, various transpl... Abstract
The American journal of medicine, Volume 135, Issue 7, 14 2 2022, Pages 915-918 Effect of Alirocumab on Incidence of Atrial Fibrillation After Acute Coronary Syndromes: Insights from the ODYSSEY OUTCOMES Trial. Lopes RD, Guimarães PO, Schwartz GG, Bhatt DL, Bittner VA, Budaj A, Dalby AJ, Diaz R, Goodman SG, Harrington RA, Jukema JW, Kiss RG, Loy M, Pordy R, Poulouin Y, Szarek M, White HD, Steg PG, ODYSSEY OUTCOMES Investigators
Background: Using data from the ODYSSEY OUTCOMES trial (NCT01663402), we sought to identify factors associated with the development of incident atrial fibrillation in patients with recent acute coronary syndrome without prior atrial fibrillation and to determine whether alirocumab treatment influenced risk of incident atrial fibrillation. Methods: ODYSSEY OUTCOMES compared alirocumab treatment with placebo in 18,924 patients with recent acute coronary syndrome and dyslipidemia despite high-inten... Abstract
European journal of nutrition, Volume 61, Issue 5, 14 2 2022, Pages 2761-2773 Adherence to the Dutch healthy diet index and change in glycemic control and cardiometabolic markers in people with type 2 diabetes. Bartels ECM, den Braver NR, Borgonjen-van den Berg KJ, Rutters F, van der Heijden A, Beulens JWJ
Purpose: To investigate whether adherence to the Dutch Healthy Diet index 2015 (DHD15-index) is associated with change in glycemic control and cardio-metabolic markers over two-year follow-up in people with type 2 diabetes (T2D). Methods: This prospective cohort study included 1202 individuals with T2D (mean age 68.7 ± 9.0 years; 62.5% male; mean HbA1c 53.8 ± 11.7 mmol/mol) from the Diabetes Care System cohort. Baseline dietary intake was assessed using a validated food frequency questionnaire,... Abstract
Cited 11 times since 2022 (3.7 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 9, 11 2 2022, Pages 854314 Pirfenidone Has Anti-fibrotic Effects in a Tissue-Engineered Model of Human Cardiac Fibrosis. Bracco Gartner TCL, Crnko S, Leiteris L, van Adrichem I, van Laake LW, Bouten CVC, Goumans MJ, Suyker WJL, Sluijter JPG, Hjortnaes J
A fundamental process in the development and progression of heart failure is fibrotic remodeling, characterized by excessive deposition of extracellular matrix proteins in response to injury. Currently, therapies that effectively target and reverse cardiac fibrosis are lacking, warranting novel therapeutic strategies and reliable methods to study their effect. Using a gelatin methacryloyl hydrogel, human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) and human fetal cardiac fibr... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 30, Issue 9, 11 2 2022, Pages 431-435 Emergency Heart failure Mortality Risk Grade may help to reduce heart failure admissions. van Hattem NE, Beeres SLMA, Mertens BJA, Antoni ML, Atsma DE, Schalij MJ, den Haan MC
Introduction: Hospital admissions for heart failure (HF) are frequent and pose a heavy burden on health care resources. Currently, the decision to hospitalise is based on clinical judgement rather than on prognostic risk stratification. The Emergency Heart failure Mortality Risk Grade (EHMRG) was recently developed to identify high-risk HF patients in the emergency department (ED). Objective: To assess the ability of the EHMRG to predict 30-day mortality in Dutch HF patients visiting the ED and... Abstract
Cited 3 times since 2022 (1 per year) source: EuropePMC
Acta dermato-venereologica, Volume 102, 11 2 2022, Pages adv00666 Identification of Risk Factors for Dupilumab-associated Ocular Surface Disease in Patients with Atopic Dermatitis. Achten RE, Van Luijk C, Van der Rijst L, Bakker D, Spekhorst L, Zuithoff N, Schuttelaar M, Romeijn G, Voorberg A, Kamsteeg M, Haeck I, De Graaf M, Thijs J, De Boer J, De Bruin-Weller M
This study identified risk factors for the development of dupilumab-associated ocular surface disease in patients with moderate-to-severe atopic dermatitis in a large prospective daily practice cohort. Data from the Dutch BioDay Registry were used to assess the risk of developing dupilumab-associated ocular surface disease, by performing univariate and multivariate logistic regression analyses. A total of 469 patients were included, of which 152/469 (32.4%) developed dupilumab-associated ocular... Abstract
Cited 1 times since 2022 (0.3 per year) source: EuropePMC
Journal of lipid research, Volume 63, Issue 5, 10 2 2022, Pages 100193 Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses. Ibi D, Boot M, Dollé MET, Jukema JW, Rosendaal FR, Christodoulides C, Neville MJ, Koivula R, Rensen PCN, Karpe F, Noordam R, Willems van Dijk K
Triglyceride (TG)-lowering LPL variants in combination with genetic LDL-C-lowering variants are associated with reduced risk of coronary artery disease (CAD). Genetic variation in the APOA5 gene encoding apolipoprotein A-V also strongly affects TG levels, but the potential clinical impact and underlying mechanisms are yet to be resolved. Here, we aimed to study the effects of APOA5 genetic variation on CAD risk and plasma lipoproteins through factorial genetic association analyses. Using data fr... Abstract
Cited 7 times since 2022 (2.4 per year) source: EuropePMC
Diagnostics (Basel, Switzerland), Volume 12, Issue 3, 9 2 2022, Pages 669 Sclerodermic Cardiomyopathy-A State-of-the-Art Review. Giucă A, Gegenava T, Mihai CM, Jurcuţ C, Săftoiu A, Gȋrniţă DM, Popescu BA, Ajmone Marsan N, Jurcuț R
Systemic sclerosis (SSc) is a chronic autoimmune disorder with unknown triggering factors, and complex pathophysiologic links which lead to fibrosis of skin and internal organs, including the heart, lungs, and gut. However, more than 100 years after the first description of cardiac disease in SSc, sclerodermic cardiomyopathy (SScCmp) is an underrecognized, occult disease with important adverse long-term prognosis. Laboratory tests, electrocardiography (ECG) and cardiovascular multimodality imagi... Abstract
Cited 11 times since 2022 (3.7 per year) source: EuropePMC
ESC heart failure, Volume 9, Issue 3, 9 2 2022, Pages 1597-1607 Right ventricular-pulmonary artery coupling in cardiac resynchronization therapy: evolution and prognosis. Stassen J, Galloo X, Hirasawa K, Chimed S, Marsan NA, Delgado V, van der Bijl P, Bax JJ
Aims: Chronic pressure overload and right ventricular (RV) dysfunction can lead to RV-pulmonary artery (PA) uncoupling in patients with heart failure. The evolution and prognostic values of RV-PA coupling assessed by echocardiography in patients undergoing cardiac resynchronization therapy (CRT) have not been thoroughly investigated. The aim of this study was to evaluate the evolution and prognostic value of tricuspid annular plane systolic excursion (TAPSE)/pulmonary artery systolic pressure (P... Abstract
Cited 1 times since 2022 (0.3 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 9, 7 1 2022, Pages 870390 Corrigendum: Robotic Cardiac Surgery in Europe: Status 2020. Cerny S, Oosterlinck W, Onan B, Singh S, Segers P, Bolcal C, Alhan C, Navarra E, Pettinari M, Van Praet F, De Praetere H, Vojacek J, Cebotaru T, Modi P, Doguet F, Franke U, Ouda A, Melly L, Malapert G, Labrousse L, Gianoli M, Agnino A, Philipsen T, Jansens JL, Folliguet T, Palmen M, Pereda D, Musumeci F, Suwalski P, Cathenis K, Van den Eynde J, Bonatti J
[This corrects the article DOI: 10.3389/fcvm.2021.827515.]. Abstract
Cited 3 times since 2022 (1 per year) source: EuropePMC
Drug discovery today, Volume 27, Issue 6, 4 1 2022, Pages 1716-1723 Advanced molecular imaging for the characterisation of complex medicines. Yilmaz D, Sharp PS, Main MJ, Simpson PB
A growing number and diversity of complex medicines is in development and reaching the market, with many of these medicines utilising innovative delivery technology to achieve appropriate biodistribution and exposure. Accurate assessment of biodistribution, cell penetration, internalised form, cargo release and efficacy are essential for the development of these medicines. Advanced imaging technologies, deploying different labelling techniques that allow the assessment of both carrier and cargo,... Abstract
Cited 5 times since 2022 (1.7 per year) source: EuropePMC
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, Volume 30, Issue 3, 3 1 2022, Pages 364-371 Normalization of Time-Intensity Curves for Quantification of Foot Perfusion Using Near-Infrared Fluorescence Imaging With Indocyanine Green. Van Den Hoven P, Tange F, Van Der Valk J, Nerup N, Putter H, Van Rijswijk C, Van Schaik J, Schepers A, Vahrmeijer A, Hamming J, Van Der Vorst J
Purpose: Near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) is gaining popularity for the quantification of tissue perfusion, including foot perfusion in patients with lower extremity arterial disease (LEAD). However, the absolute fluorescence intensity is influenced by patient-and system-related factors limiting reliable and valid quantification. To enhance the quality of quantitative perfusion assessment using ICG NIR fluorescence imaging, normalization of the measured time... Abstract
Cited 3 times since 2022 (1 per year) source: EuropePMC
Seminars in nuclear medicine, Volume 52, Issue 5, 2 1 2022, Pages 597-610 Nuclear medicine imaging methods of radiation-induced cardiotoxicity. Polomski ES, Antoni ML, Jukema JW, Kroep JR, Dibbets-Schneider P, Sattler MGA, de Geus-Oei LF
Breast cancer survival is significantly improved over the past decades due to major improvements in anti-tumor therapies and the implementation of regular screening, which leads to early detection of breast cancer. Therefore, it is of utmost importance to prevent patients from long-term side effects, including radiotherapy-induced cardiotoxicity. Radiotherapy may contribute to damage of myocardial structures on the cellular level, which eventually could result in various types of cardiovascular... Abstract
Cited 2 times since 2022 (0.7 per year) source: EuropePMC
Vascular and endovascular surgery, Volume 56, Issue 5, 2 1 2022, Pages 472-479 Doppler Ultrasonography Derived Maximal Systolic Acceleration: Value Determination With Artificially Induced Stenosis. Brouwers JJWM, van Doorn LP, Pronk L, van Wissen RC, Putter H, Schepers A, Hamming JF
BackgroundIn diagnosing peripheral arterial disease (PAD), medial arterial calcification (MAC) hampers arterial compression and could lead to unreliable ankle brachial index (ABI), toe brachial index (TBI) and toe pressure (TP). Doppler ultrasonography (DUS) derived maximal systolic acceleration (ACCmax) might be more accurate to diagnose PAD. In an in vitro study, a strong correlation between ACCmax and the severity of stenotic disease was determined. The aim of this study was to investigate th... Abstract
Cited 17 times since 2022 (5.7 per year) source: EuropePMC
JACC. Cardiovascular interventions, Volume 15, Issue 5, 1 1 2022, Pages 523-532 The PARTNER 3 Bicuspid Registry for Transcatheter Aortic Valve Replacement in Low-Surgical-Risk Patients. Williams MR, Jilaihawi H, Makkar R, O'Neill WW, Guyton R, Malaisrie SC, Brown DL, Blanke P, Leipsic JA, Pibarot P, Hahn RT, Leon MB, Cohen DJ, Bax JJ, Kodali SK, Mack MJ, Lu M, Webb JG
Objectives: The study compared 1-year outcomes between transcatheter aortic valve replacement (TAVR) patients with bicuspid aortic valve (BAV) morphology and clinically similar patients having tricuspid aortic valve (TAV) morphology. Background: There are limited prospective data on TAVR using the SAPIEN 3 device in low-surgical-risk patients with severe, symptomatic aortic stenosis and bicuspid anatomy. Methods: Low-risk, severe aortic stenosis patients with BAV were candidates for the PARTNER... Abstract
Cited 3 times since 2022 (1 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 4, 1 1 2022, Pages 578-585 Prognostic implications of cardiac damage classification based on computed tomography in severe aortic stenosis. Hirasawa K, vanRosendael PJ, Fortuni F, Singh GK, Kuneman JH, Vollema EM, Ajmone Marsan N, Knuuti J, Bax JJ, Delgado V
Aims: An echocardiographic staging system of severe aortic stenosis (AS) based on additional extra-valvular cardiac damage has been associated with prognosis after transcatheter aortic valve implantation (TAVI). Multidetector row computed tomography (MDCT) is key in the evaluation of AS patients undergoing TAVI and can potentially detect extra-valvular cardiac damage. This study aimed at evaluating the prognostic implications of an MDCT staging system of severe AS in patients undergoing TAVI. Me... Abstract
Cited 2 times since 2022 (0.7 per year) source: EuropePMC
European journal of cardiovascular nursing, Volume 21, Issue 2, 1 1 2022, Pages 169-173 Implantable cardioverter-defibrillators and the older patient: the Dutch clinical practice. Yilmaz D, Egorova AD, Schalij MJ, van Erven L
Background and objective: Balance between benefit and burden of implantable cardioverter-defibrillator (ICD) therapy is more debatable in older patients, compared to younger patients. Of around 6000 yearly implanted ICDs in the Netherlands, 1:4 is received by patients ≥75 years. We aimed to evaluate the current clinical practice in the Netherlands for ICD implants and generator replacements, with a special focus on the older ICD patients. Research design and methods: Cardiologists from all Dutch... Abstract
Cited 5 times since 2022 (1.7 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 4, 1 1 2022, Pages 447-449 How to do lung ultrasound. Stassen J, Bax JJ
Cited 24 times since 2022 (8 per year) source: EuropePMC
Diabetes care, Volume 45, Issue 3, 1 1 2022, Pages 674-683 Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts. DiCorpo D, LeClair J, Cole JB, Sarnowski C, Ahmadizar F, Bielak LF, Blokstra A, Bottinger EP, Chaker L, Chen YI, Chen Y, de Vries PS, Faquih T, Ghanbari M, Gudmundsdottir V, Guo X, Hasbani NR, Ibi D, Ikram MA, Kavousi M, Leonard HL, Leong A, Mercader JM, Morrison AC, Nadkarni GN, Nalls MA, Noordam R, Preuss M, Smith JA, Trompet S, Vissink P, Yao J, Zhao W, Boerwinkle E, Goodarzi MO, Gudnason V, Jukema JW, Kardia SLR, Loos RJF, Liu CT, Manning AK, Mook-Kanamori D, Pankow JS, Picavet HSJ, Sattar N, Simonsick EM, Verschuren WMM, Willems van Dijk K, Florez JC, Rotter JI, Meigs JB, Dupuis J, Udler MS
Objective: Type 2 diabetes (T2D) has heterogeneous patient clinical characteristics and outcomes. In previous work, we investigated the genetic basis of this heterogeneity by clustering 94 T2D genetic loci using their associations with 47 diabetes-related traits and identified five clusters, termed β-cell, proinsulin, obesity, lipodystrophy, and liver/lipid. The relationship between these clusters and individual-level metabolic disease outcomes has not been assessed. Research design and methods:... Abstract