9543 results
Cited 26 times since 2016 (2.8 per year)
source: EuropePMC
Clinical pharmacokinetics,
Volume 55, Issue 9, 1 1 2016, Pages 1129-1143
The Effect of Weight and CYP3A5 Genotype on the Population Pharmacokinetics of Tacrolimus in Stable Paediatric Renal Transplant Recipients.
Prytuła AA, Cransberg K, Bouts AH, van Schaik RH, de Jong H, de Wildt SN, Mathôt RA
Background: The aim of this study was to develop a population pharmacokinetic model of tacrolimus in paediatric patients at least 1 year after renal transplantation and simulate individualised dosage regimens. Patients and methods: We included 54 children with median age of 11.1 years (range 3.8-18.4 years) with 120 pharmacokinetic profiles performed over 2 to 4 h. The pharmacokinetic analysis was performed using the non-linear mixed-effects modelling software (NONMEM(®)). The impact of covariat...
Abstract
Cited 5 times since 2016 (0.5 per year)
source: EuropePMC
Current opinion in cardiology,
Volume 31, Issue 5, 1 1 2016, Pages 523-530
Mechanical dyssynchrony in patients with heart failure and reduced ejection fraction: how to measure?
Khidir MJ, Delgado V, Ajmone Marsan N, Bax JJ
Purpose of review: This article summarizes the most recent imaging techniques to assess left ventricular mechanical dyssynchrony and discusses their value to predict response to cardiac resynchronization therapy (CRT) together with assessment of myocardial scar and cardiac venous anatomy. Recent findings: Left ventricular mechanical dyssynchrony has been associated with prognosis of heart failure patients and has been shown to influence the efficacy of CRT. Although current guidelines do not rec...
Abstract
Cited 14 times since 2016 (1.5 per year)
source: EuropePMC
Journal of the peripheral nervous system : JPNS,
Volume 21, Issue 3, 1 1 2016, Pages 121-127
Intravenous immunoglobulin treatment in chronic inflammatory demyelinating polyradiculoneuropathy, a time to start and a time to stop.
Adrichem ME, Eftimov F, van Schaik IN
Intravenous immunoglobulin (IVIg) is often used as preferred treatment in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Several studies highlighted the short-term efficacy of IVIg for CIDP yet many patients need maintenance therapy. Notwithstanding the fact IVIg has been used for over 30 years in CIDP, there is only limited evidence to guide dosage and interval during maintenance treatment. The variation in disease course, lack of biomarkers, and fear of deterioration after s...
Abstract
Cited 27 times since 2016 (2.9 per year)
source: EuropePMC
Obesity surgery,
Volume 26, Issue 9, 1 1 2016, Pages 2051-2058
The Effect of Roux-en-Y Gastric Bypass Surgery in Morbidly Obese Patients on Pharmacokinetics of (Acetyl)Salicylic Acid and Omeprazole: the ERY-PAO Study.
Mitrov-Winkelmolen L, van Buul-Gast MW, Swank DJ, Overdiek HWPM, van Schaik RHN, Touw DJ
Background: Data on the absorption of orally administered drugs following Roux-en-Y gastric bypass (RYGB) surgery in obese patients are limited and inconclusive. As it is difficult to predict changes in absorption, studies on frequently used drugs in this population are necessary. Acetylsalicylic acid (ASA) and omeprazole are two commonly prescribed drugs in obese patients. Methods: In this repeated measures study, omeprazole and salicylic acid (SA) serum concentrations were measured before and...
Abstract
Brain pathology (Zurich, Switzerland),
Volume 26, Issue 5, 1 1 2016, Pages 672
Letter in response to Maderna E et al, Measles Inclusion-Body Encephalitis: Neuronal Phosphorylated Tau Protein Is Present in the Biopsy but Not in the Autoptic Specimens of the Same Patient, Brain Pathology, doi: 10.1111/bpa.12332.
Yuksel D, Yılmaz D, Yurttutan Uyar N, Senbil N, Gürer Y, Anlar B
Abstract
Cited 34 times since 2016 (3.7 per year)
source: EuropePMC
Open forum infectious diseases,
Volume 3, Issue 4, 30 5 2016, Pages ofw178
Duration of Colonization With <i>Klebsiella pneumoniae</i> Carbapenemase-Producing Bacteria at Long-Term Acute Care Hospitals in Chicago, Illinois.
Haverkate MR, Weiner S, Lolans K, Moore NM, Weinstein RA, Bonten MJ, Hayden MK, Bootsma MC
Background. High prevalence of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae has been reported in long-term acute care hospitals (LTACHs), in part because of frequent readmissions of colonized patients. Knowledge of the duration of colonization with KPC is essential to identify patients at risk of KPC colonization upon readmission and to make predictions on the effects of transmission control measures. Methods. We analyzed data on surveillance isolates that were collec...
Abstract
Cited 26 times since 2016 (2.8 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 152, Issue 6, 28 4 2016, Pages 1572-1579.e3
Allografts in aortic position: Insights from a 27-year, single-center prospective study.
Arabkhani B, Bekkers JA, Andrinopoulou ER, Roos-Hesselink JW, Takkenberg JJ, Bogers AJ
Objective: Over the past decades, the indication for allograft implantation in aortic position has evolved. The purpose of this study is to report long-term survival, allograft durability, and potential risk factors. Methods: Between 1987 and 2010, 353 patients underwent aortic valve replacements via allograft (92 subcoronary, 261 root replacement; 98% aortic allografts). Patient characteristics, survival, valve durability, and valve-related events were analyzed. Patients also were followed with...
Abstract
Cited 4057 times since 2016 (439.1 per year)
source: EuropePMC
European heart journal,
Volume 37, Issue 38, 27 4 2016, Pages 2893-2962
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS.
Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, Castella M, Diener HC, Heidbuchel H, Hendriks J, Hindricks G, Manolis AS, Oldgren J, Popescu BA, Schotten U, Van Putte B, Vardas P, ESC Scientific Document Group
Abstract
Cited 258 times since 2016 (27.9 per year)
source: EuropePMC
European journal of heart failure,
Volume 19, Issue 1, 27 4 2016, Pages 9-42
2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC).
Zamorano JL, Lancellotti P, Rodriguez Muñoz D, Aboyans V, Asteggiano R, Galderisi M, Habib G, Lenihan DJ, Lip GY, Lyon AR, Lopez Fernandez T, Mohty D, Piepoli MF, Tamargo J, Torbicki A, Suter TM, Zamorano JL, Aboyans V, Achenbach S, Agewall S, Badimon L, Barón-Esquivias G, Baumgartner H, Bax JJ, Bueno H, Carerj S, Dean V, Erol Ç, Fitzsimons D, Gaemperli O, Kirchhof P, Kolh P, Lancellotti P, Lip GY, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Roffi M, Torbicki A, Vaz Carneiro A, Windecker S, Authors/Task Force Members, ESC Committee for Practice Guidelines (CPG), Document Reviewers
Abstract
Cited 3 times since 2016 (0.3 per year)
source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions,
Volume 90, Issue 1, 27 4 2016, Pages E1-E10
Anatomical and functional assessment of Tryton bifurcation stent before and after final kissing balloon dilatation: Evaluations by three-dimensional coronary angiography, optical coherence tomography imaging and fractional flow reserve.
Pyxaras SA, Toth GG, Di Gioia G, Ughi GJ, Tu S, Rusinaru D, Adriaenssens T, Reiber JHC, Leon MB, Bax JJ, Wijns W
Objectives: To assess the anatomical and functional impact of final kissing balloon inflation (FKBI) after implantation of a dedicated bifurcation stent system. Background: Current evidence suggests clinical benefit of FKBI in patients undergoing bifurcation dilatation using the Tryton side branch stent (Tryton-SBS). We hypothesized that FKBI improves anatomical reconstruction and functional results of bifurcation treated by Tryton-SBS. Methods: An unselected group of patients with complex bifur...
Abstract
Cited 1173 times since 2016 (126.9 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 18, Issue 11, 27 4 2016, Pages 1609-1678
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS.
Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, Castella M, Diener HC, Heidbuchel H, Hendriks J, Hindricks G, Manolis AS, Oldgren J, Popescu BA, Schotten U, Van Putte B, Vardas P, Agewall S, Camm J, Baron Esquivias G, Budts W, Carerj S, Casselman F, Coca A, De Caterina R, Deftereos S, Dobrev D, Ferro JM, Filippatos G, Fitzsimons D, Gorenek B, Guenoun M, Hohnloser SH, Kolh P, Lip GY, Manolis A, McMurray J, Ponikowski P, Rosenhek R, Ruschitzka F, Savelieva I, Sharma S, Suwalski P, Tamargo JL, Taylor CJ, Van Gelder IC, Voors AA, Windecker S, Zamorano JL, Zeppenfeld K
Abstract
Cited 1677 times since 2016 (181.5 per year)
source: EuropePMC
European heart journal,
Volume 37, Issue 39, 27 4 2016, Pages 2999-3058
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias.
Catapano AL, Graham I, De Backer G, Wiklund O, Chapman MJ, Drexel H, Hoes AW, Jennings CS, Landmesser U, Pedersen TR, Reiner Ž, Riccardi G, Taskinen MR, Tokgozoglu L, Verschuren WMM, Vlachopoulos C, Wood DA, Zamorano JL, Cooney MT, ESC Scientific Document Group
Abstract
Cited 1704 times since 2016 (184.4 per year)
source: EuropePMC
European heart journal,
Volume 37, Issue 36, 26 4 2016, Pages 2768-2801
2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC).
Zamorano JL, Lancellotti P, Rodriguez Muñoz D, Aboyans V, Asteggiano R, Galderisi M, Habib G, Lenihan DJ, Lip GYH, Lyon AR, Lopez Fernandez T, Mohty D, Piepoli MF, Tamargo J, Torbicki A, Suter TM, ESC Scientific Document Group
Abstract
Cited 8 times since 2016 (0.9 per year)
source: EuropePMC
Congenital heart disease,
Volume 12, Issue 1, 25 4 2016, Pages 32-39
Surgical outcome in pediatric patients with Ebstein's anomaly: A multicenter, long-term study.
Geerdink LM, du Marchie Sarvaas GJ, Kuipers IM, Helbing WA, Delhaas T, Ter Heide H, Rozendaal L, de Korte CL, Singh SK, Ebels T, Hazekamp MG, Haas F, Bogers AJ, Kapusta L
Objective: Surgical outcomes of pediatric patients with Ebstein's anomaly are often described as part of all-age-inclusive series. Our objective is to focus on patients treated surgically in childhood (0-18 y). We study the intended treatment (biventricular or 1.5 ventricle repair or univentricular palliation), freedom from unplanned reoperation and survival of this specific age group, in a nationwide study. Design: Records of all Ebstein's anomaly patients born between 1980 and 2013 w...
Abstract
Cited 129 times since 2016 (13.9 per year)
source: EuropePMC
Angewandte Chemie (International ed. in English),
Volume 55, Issue 40, 24 4 2016, Pages 12440-12444
Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors.
Jain PK, Ramanan V, Schepers AG, Dalvie NS, Panda A, Fleming HE, Bhatia SN
The ability to remotely trigger CRISPR/Cas9 activity would enable new strategies to study cellular events with greater precision and complexity. In this work, we have developed a method to photocage the activity of the guide RNA called "CRISPR-plus" (CRISPR-precise light-mediated unveiling of sgRNAs). The photoactivation capability of our CRISPR-plus method is compatible with the simultaneous targeting of multiple DNA sequences and supports numerous modifications that can enable guide...
Abstract
Angiology,
Volume 68, Issue 6, 23 4 2016, Pages 519-527
Very Long-Term Follow-Up After Coronary Rotational Atherectomy: A Single-Center Experience.
Tohamy A, Klomp M, Putter H, Youssef A, Shams-Eddin H, Abdelsabour M, Schalij MJ, Jukema JW
We assessed the very long-term follow-up of a large cohort of unselected patients treated with coronary rotational atherectomy (RA). All 143 patients who underwent RA at our institution from 2000 to 2013 and with complete baseline and follow-up information were analyzed in a retrospective manner. Major adverse cardiac events (MACE) were defined as the composite of target vessel revascularization (TVR), acute myocardial infarction, and all-cause mortality. The mean follow-up was 8.2 years. The 10...
Abstract
Cited 23 times since 2016 (2.5 per year)
source: EuropePMC
The American journal of cardiology,
Volume 118, Issue 10, 23 4 2016, Pages 1533-1538
Comparison of Quantity of Calcific Deposits by Multidetector Computed Tomography in the Aortic Valve and Coronary Arteries.
van Rosendael PJ, Kamperidis V, Kong WK, van Rosendael AR, Marsan NA, Bax JJ, Delgado V
The aim of this study was to compare the calcium burden of the aortic valve and coronary arteries with multidetector computed tomography (MDCT) in a propensity score-matched population of patients with a bicuspid versus a tricuspid aortic valve. From an ongoing clinical registry of patients who underwent MDCT, 70 patients with bicuspid aortic valve and 210 patients with tricuspid aortic valve were matched based on age, gender, cardiovascular risk factors, chest pain symptoms, and MDCT indication...
Abstract
Cited 29 times since 2016 (3.1 per year)
source: EuropePMC
Journal of clinical pharmacology,
Volume 57, Issue 2, 23 4 2016, Pages 235-246
CYP2C19 Genotype-Dependent Pharmacokinetic Drug Interaction Between Voriconazole and Ritonavir-Boosted Atazanavir in Healthy Subjects.
Zhu L, Brüggemann RJ, Uy J, Colbers A, Hruska MW, Chung E, Sims K, Vakkalagadda B, Xu X, van Schaik RH, Burger DM, Bertz RJ
Voriconazole, a broad-spectrum triazole antifungal agent, is metabolized by cytochrome P450 (CYP) 2C19 and, to a lesser extent, by CYP3A. Genetic polymorphism of CYP2C19 not only plays a prominent role in its disposition but may also influence potential drug interactions with CYP450 modulators such as ritonavir. This study assessed 2-way drug interactions of voriconazole added on to ritonavir-boosted atazanavir in both CYP2C19 extensive-metabolizer (EM) and poor-metabolizer (PM) healthy subjects...
Abstract
Cited 24 times since 2016 (2.6 per year)
source: EuropePMC
BMC sports science, medicine & rehabilitation,
Volume 8, Issue 1, 23 4 2016, Pages 25
Exergaming (XBOX Kinect™) versus traditional gym-based exercise for postural control, flow and technology acceptance in healthy adults: a randomised controlled trial.
Barry G, van Schaik P, MacSween A, Dixon J, Martin D
Background: The use of exergaming is a potential alternative to traditional methods of balance training, which can be repetitive and somewhat monotonous. The purpose of this study was to assess the effects of exergaming using XBOX Kinect™ versus traditional gym-based exercise with no virtual stimuli (TGB) on postural control, technology acceptance, flow experience and exercise intensity, in young healthy adults. Methods: Fifty healthy active adults (age: 33.8 ± 12.7 years, height: 172.9 ± 11.9 c...
Abstract
Cited 3 times since 2016 (0.3 per year)
source: EuropePMC
Pharmacogenomics,
Volume 17, Issue 14, 22 4 2016, Pages 1533-1545
Minimum information required for a DMET experiment reporting.
Kumuthini J, Mbiyavanga M, Chimusa ER, Pathak J, Somervuo P, Van Schaik RH, Dolzan V, Mizzi C, Kalideen K, Ramesar RS, Macek M, Patrinos GP, Squassina A
Aim: To provide pharmacogenomics reporting guidelines, the information and tools required for reporting to public omic databases. Material & methods: For effective DMET data interpretation, sharing, interoperability, reproducibility and reporting, we propose the Minimum Information required for a DMET Experiment (MIDE) reporting. Results: MIDE provides reporting guidelines and describes the information required for reporting, data storage and data sharing in the form of XML. Conclusion: The...
Abstract
