6881 results
Cited 1 times since 2023 (0.5 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 93, 10 2 2023, Pages 308-318
Learning Curve Analysis of Complex Endovascular Aortic Repair.
Warmerdam BWCM, Stevens M, van Rijswijk CSP, Eefting D, van der Meer RW, Putter H, Hamming JF, van der Vorst JR, van Schaik J
Background: When introducing new techniques, attention must be paid to learning curve. Besides quantitative outcomes, qualitative factors of influence should be taken into consideration. This retrospective cohort study describes the quantitative learning curve of complex endovascular aortic repair (EVAR) in a nonhigh-volume academic center and provides qualitative factors that were perceived as contributors to this learning curve. With these factors, we aim to aid in future implementation of new...
Abstract
Cited 4 times since 2023 (1.9 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 10, 9 2 2023, Pages 1018167
Thoracic aortopathy in Marfan syndrome overlaps with mechanisms seen in bicuspid aortic valve disease.
Grewal N, Dolmaci O, Jansen E, Klautz R, Driessen A, Poelmann RE
Background: Thoracic aortopathy is a serious complication which is more often seen in patients with Marfan syndrome (MFS) and patients with a bicuspid aortic valve (BAV) than in individuals with a tricuspid aortic valve (TAV). The identification of common pathological mechanisms leading to aortic complications in non-syndromic and syndromic diseases would significantly improve the field of personalized medicine. Objective: This study sought to compare thoracic aortopathy between MFS, BAV, and TA...
Abstract
Cited 4 times since 2023 (1.9 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 16, Issue 6, 8 2 2023, Pages 837-855
Managing Patients With Moderate Aortic Stenosis.
Stassen J, Ewe SH, Pio SM, Pibarot P, Redfors B, Leipsic J, Genereux P, Van Mieghem NM, Kuneman JH, Makkar R, Hahn RT, Playford D, Marsan NA, Delgado V, Ben-Yehuda O, Leon MB, Bax JJ
Current guidelines recommend that clinical surveillance for patients with moderate aortic stenosis (AS) and aortic valve replacement (AVR) may be considered if there is an indication for coronary revascularization. Recent observational studies, however, have shown that moderate AS is associated with an increased risk of cardiovascular events and mortality. Whether the increased risk of adverse events is caused by associated comorbidities, or to the underlying moderate AS itself, is incompletely...
Abstract
Cited 2 times since 2023 (1 per year)
source: EuropePMC
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
Volume 160, 6 1 2023, Pages 114369
Toward model-informed precision dosing for tamoxifen: A population-pharmacokinetic model with a continuous CYP2D6 activity scale.
Agema BC, Buijs SM, Sassen SDT, Mürdter TE, Schwab M, Koch BCP, Jager A, van Schaik RHN, Mathijssen RHJ, Koolen SLW
Background: Tamoxifen is important in the adjuvant treatment of breast cancer. A plasma concentration of the active metabolite endoxifen of > 16 nM is associated with a lower risk of breast cancer-recurrence. Since inter-individual variability is high and > 20 % of patients do not reach endoxifen levels > 16 nM with the standard dose tamoxifen, therapeutic drug monitoring is advised. However, ideally, the correct tamoxifen dose should be known prior to start of therapy. Our aim is to de...
Abstract
Cited 14 times since 2023 (6.8 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 16, Issue 2, 3 1 2023, Pages e014672
Pericoronary Adipose Tissue Attenuation in Patients With Acute Coronary Syndrome Versus Stable Coronary Artery Disease.
Kuneman JH, van Rosendael SE, van der Bijl P, van Rosendael AR, Kitslaar PH, Reiber JHC, Jukema JW, Leon MB, Ajmone Marsan N, Knuuti J, Bax JJ
Background: Pericoronary adipose tissue (PCAT) attenuation has been associated with coronary inflammation and can be evaluated with coronary computed tomography angiography. The aims of this study were to compare the PCAT attenuation across precursors of culprit and nonculprit lesions of patients with acute coronary syndrome versus stable coronary artery disease (CAD). Methods: In this case-control study, patients with suspected CAD who underwent coronary computed tomography angiography were inc...
Abstract
BMC cancer,
Volume 23, Issue 1, 2 1 2023, Pages 115
Cardiac and obstetric outcomes of pregnancies for women after cardiotoxic therapy in childhood: a single center observational study.
Heemelaar JC, Heemelaar S, Hertel SN, Jukema JW, Sueters M, Louwerens M, Antoni ML
Background: Childhood cancer survivors (CCS) are at increased risk of cardiomyopathy during pregnancy if they have prior cardiotoxic exposure. Currently, there is no consensus on the necessity, timing and modality of cardiac monitoring during and after pregnancy. Therefore, we examined cardiac function using contemporary echocardiographic parameters during pregnancy in CCS with cardiotoxic treatment exposure, and we observed obstetric outcomes in CCS, including in women without previous cardioto...
Abstract
Frontiers in cardiovascular medicine,
Volume 10, 2 1 2023, Pages 1097201
Commentary: Transforming growth factor serum concentrations in patients with proven non-syndromic aortopathy.
Grewal N, Klautz R, Poelmann RE
Abstract
Cited 1 times since 2023 (0.5 per year)
source: EuropePMC
Life (Basel, Switzerland),
Volume 13, Issue 2, 2 1 2023, Pages 428
Association of Circulating Neutrophils with Relative Volume of Lipid-Rich Necrotic Core of Coronary Plaques in Stable Patients: A Substudy of SMARTool European Project.
Sbrana S, Cecchettini A, Bastiani L, Mazzone A, Vozzi F, Caselli C, Neglia D, Clemente A, Scholte AJHA, Parodi O, Pelosi G, Rocchiccioli S
Background and aims: Coronary atherosclerosis is a chronic non-resolving inflammatory process wherein the interaction of innate immune cells and platelets plays a major role. Circulating neutrophils, in particular, adhere to the activated endothelium and migrate into the vascular wall, promoting monocyte recruitment and influencing plaque phenotype and stability at all stages of its evolution. We aimed to evaluate, by flow cytometry, if blood neutrophil number and phenotype-including their pheno...
Abstract
Cited 17 times since 2023 (8.2 per year)
source: EuropePMC
Nature medicine,
Volume 29, Issue 3, 2 1 2023, Pages 588-592
High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial.
van Dorp J, Pipinikas C, Suelmann BBM, Mehra N, van Dijk N, Marsico G, van Montfoort ML, Hackinger S, Braaf LM, Amarante T, van Steenis C, McLay K, Daletzakis A, van den Broek D, van de Kamp MW, Hendricksen K, de Feijter JM, Boellaard TN, Meijer RP, van der Heijden AG, Rosenfeld N, van Rhijn BWG, Jones G, van der Heijden MS
Cohort 1 of the phase 1B NABUCCO trial showed high pathological complete response (pCR) rates with preoperative ipilimumab plus nivolumab in stage III urothelial cancer (UC). In cohort 2, the aim was dose adjustment to optimize responses. Additionally, we report secondary endpoints, including efficacy and tolerability, in cohort 2 and the association of presurgical absence of circulating tumor DNA (ctDNA) in urine and plasma with clinical outcome in both cohorts. Thirty patients received two cyc...
Abstract
Clinical medicine insights. Pediatrics,
Volume 17, 1 1 2023, Pages 11795565221150193
Evaluation of Patients With Congenital Anal Stenosis, Single Center Study.
Karaçay Ş, Yılmaz D, Ugras M
Abstract
Cited 4 times since 2023 (1.9 per year)
source: EuropePMC
Nature communications,
Volume 14, Issue 1, 1 1 2023, Pages 544
Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response.
Dekkers KF, Slieker RC, Ioan-Facsinay A, van Iterson M, BIOS consortium, Ikram MA, van Greevenbroek MMJ, Veldink JH, Franke L, Boomsma DI, Slagboom PE, Jukema JW, Heijmans BT
Immune cell function can be altered by lipids in circulation, a process potentially relevant to lipid-associated inflammatory diseases including atherosclerosis and rheumatoid arthritis. To gain further insight in the molecular changes involved, we here perform a transcriptome-wide association analysis of blood triglycerides, HDL cholesterol, and LDL cholesterol in 3229 individuals, followed by a systematic bidirectional Mendelian randomization analysis to assess the direction of effects and con...
Abstract
Cited 14 times since 2023 (6.7 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 25, Issue 1, 1 1 2023, Pages 199-210
European Society of Cardiology quality indicators for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death.
Aktaa S, Tzeis S, Gale CP, Ackerman MJ, Arbelo E, Behr ER, Crotti L, d'Avila A, de Chillou C, Deneke T, Figueiredo M, Friede T, Leclercq C, Merino JL, Semsarian C, Verstrael A, Zeppenfeld K, Zeppenfeld K, Tfelt-Hansen J, Reichlin T
To develop a suite of quality indicators (QIs) for the management of patients with ventricular arrhythmias (VA) and the prevention of sudden cardiac death (SCD). The Working Group comprised experts in heart rhythm management including Task Force members of the 2022 European Society of Cardiology (ESC) Clinical Practice Guidelines for the management of patients with VA and the prevention of SCD, members of the European Heart Rhythm Association, international experts, and a patient representative....
Abstract
Cited 1 times since 2023 (0.5 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 25, Issue 2, 1 1 2023, Pages 478-486
The transmural activation interval: a new mapping tool to identify ventricular tachycardia substrates in right ventricular cardiomyopathy.
Venlet J, Piers SR, Hoogendoorn J, Androulakis AFA, de Riva M, van der Geest RJ, Zeppenfeld K, Zeppenfeld K
Aims: In right ventricular cardiomyopathy (RVCM), intramural scar may prevent rapid transmural activation, which may facilitate subepicardial ventricular tachycardia (VT) circuits. A critical transmural activation delay determined during sinus rhythm (SR) may identify VT substrates in RVCM. Methods and results: Consecutive patients with RVCM who underwent detailed endocardial-epicardial mapping and ablation for scar-related VT were enrolled. The transmural activation interval (TAI, first endocar...
Abstract
Cited 10 times since 2023 (4.8 per year)
source: EuropePMC
European journal of endocrinology,
Volume 188, Issue 2, 1 1 2023, Pages lvad009
Diagnostic criteria for the hypothalamic syndrome in childhood.
van Santen HM, van Schaik J, van Roessel IMAA, Beckhaus J, Boekhoff S, Müller HL
Objective: Hypothalamic syndrome (HS) in childhood is a rare condition. Its epidemiology is not well known because incidence and prevalence are related to very rare underlying diseases. In addition, different criteria for the syndrome are used across studies. Recognizing the HS may be difficult, due to its rareness and variety of symptoms. Having diagnostic criteria for signs and symptoms of hypothalamic dysfunction may aid in early recognition and diagnosis, in the reporting and understanding o...
Abstract
Cited 3 times since 2023 (1.4 per year)
source: EuropePMC
Diabetes care,
Volume 46, Issue 2, 1 1 2023, Pages 416-424
Diabetes, Atherosclerosis, and Stenosis by AI.
Jonas RA, Crabtree TR, Jennings RS, Marques H, Katz RJ, Chang HJ, Stuijfzand WJ, van Rosendael AR, Choi JH, Doh JH, Her AY, Koo BK, Nam CW, Park HB, Shin SH, Cole J, Gimelli A, Khan MA, Lu B, Gao Y, Nabi F, Nakazato R, Schoepf UJ, Driessen RS, Bom MJ, Thompson RC, Jang JJ, Ridner M, Rowan C, Avelar E, Généreux P, Knaapen P, de Waard GA, Pontone G, Andreini D, Al-Mallah MH, Guglielmo M, Bax JJ, Earls JP, Min JK, Choi AD, Villines TC
Objective: This study evaluates the relationship between atherosclerotic plaque characteristics (APCs) and angiographic stenosis severity in patients with and without diabetes. Whether APCs differ based on lesion severity and diabetes status is unknown. Research design and methods: We retrospectively evaluated 303 subjects from the Computed TomogRaphic Evaluation of Atherosclerotic Determinants of Myocardial IsChEmia (CREDENCE) trial referred for invasive coronary angiography with coronary compu...
Abstract
Cited 7 times since 2023 (3.4 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 63, Issue 2, 1 1 2023, Pages ezac514
A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the AVIATOR database.
Arabkhani B, Klautz RJM, de Heer F, De Kerchove L, El Khoury G, Lansac E, Schäfers HJ, El-Hamamsy I, Lenoir M, Aramendi JI, Meuris B, Verbrugghe P, Kluin J, Koolbergen DR, Bouchot O, Rudez I, Kolesar A, van Brakel TJ
Objectives: Our goal was to evaluate the outcome of valve-sparing root replacement (VSRR) and to compare the outcomes to those of patients having composite valve-graft conduit aortic root replacement (CVG-ARR) in a cohort of patients with aortic root aneurysm ± valve insufficiency, without valvular stenosis. Although valve-sparing procedures are preferable in young patients, there is a lack of comparative data in comparable patients. Methods: The VSRR procedures were performed in 2005 patients,...
Abstract
European heart journal,
Volume 44, Issue 7, 1 1 2023, Pages 554-556
The year in cardiovascular medicine 2022: the top 10 papers in cardiovascular imaging.
Bucciarelli-Ducci C, Ajmone-Marsan N
Abstract
Cited 3 times since 2023 (1.4 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 25, Issue 1, 1 1 2023, Pages 49-58
Mobile health vs. standard care after cardiac surgery: results of The Box 2.0 study.
Biersteker TE, Boogers MJ, Schalij MJ, Penning de Vries BBL, Groenwold RHH, van Alem AP, de Weger A, van Hof N, Treskes RW
Aims: Postoperative atrial fibrillation (POAF) is a common complication of cardiac surgery, yet difficult to detect in ambulatory patients. The primary aim of this study is to investigate the effect of a mobile health (mHealth) intervention on POAF detection after cardiac surgery. Methods and results: We performed an observational cohort study among 730 adult patients who underwent cardiac surgery at a tertiary care hospital in The Netherlands. Of these patients, 365 patients received standard c...
Abstract
Cited 2 times since 2023 (1 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 24, Issue 3, 1 1 2023, Pages 327-335
Feature-tracking computed tomography left atrial strain and long-term survival after transcatheter aortic valve implantation.
Hirasawa K, Singh GK, Kuneman JH, Gegenava T, van der Kley F, Hautemann D, Reiber JHC, Ajmone Marsan N, Bax JJ, Delgado V
Aims: Aortic stenosis (AS) induces left atrial (LA) remodelling through the increase of left ventricular (LV) filling pressures. Peak LA longitudinal strain (PALS), reflecting LA reservoir function, has been proposed as a prognostic marker in patients with AS. Feature-tracking (FT) multi-detector computed tomography (MDCT) allows assessment of LA strain from MDCT data. The aim of this study is to investigate the association between PALS using FT MDCT and survival in patients with severe AS who u...
Abstract
Cited 11 times since 2023 (5.3 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 81, Issue 8, 1 1 2023, Pages 743-752
Cardiac Damage and Quality of Life After Aortic Valve Replacement in the PARTNER Trials.
Généreux P, Cohen DJ, Pibarot P, Redfors B, Bax JJ, Zhao Y, Prince H, Makkar RR, Kapadia S, Thourani VH, Mack MJ, Nazif TM, Lindman BR, Babaliaros V, Russo M, McCabe JM, Gillam LD, Alu MC, Hahn RT, Webb JG, Leon MB, Arnold SV
Background: The extent of extravalvular cardiac damage is associated with increased risk of adverse events among patients with severe aortic stenosis undergoing aortic valve replacement (AVR). Objectives: The goal was to describe the association of cardiac damage on health status before and after AVR. Methods: Patients from the PARTNER (Placement of Aortic Transcatheter Valves) 2 and 3 trials were pooled and classified by echocardiographic cardiac damage stage at baseline and 1 year as previousl...
Abstract
