6128 results
Cited 12 times since 2020 (2.5 per year)
source: EuropePMC
JACC. Heart failure,
Volume 8, Issue 8, 10 2 2020, Pages 627-636
Prognostic Implications of Staging Right Heart Failure in Patients With Significant Secondary Tricuspid Regurgitation.
Dietz MF, Prihadi EA, van der Bijl P, Ajmone Marsan N, Delgado V, Bax JJ
Objectives: The purpose of this study was to evaluate the prognostic value of staging right heart failure (RHF) in patients with significant secondary tricuspid regurgitation (TR). Background: Right ventricular dysfunction (RVD), defined as tricuspid annular plane systolic excursion
Abstract
Cited 5 times since 2020 (1.1 per year)
source: EuropePMC
Medical science educator,
Volume 30, Issue 3, 9 2 2020, Pages 1211-1219
Making a Lecture Stick: the Effect of Spaced Instruction on Knowledge Retention in Medical Education.
Timmer MCJ, Steendijk P, Arend SM, Versteeg M
Introduction: Poor knowledge retention is a persistent problem among medical students. This challenging issue may be addressed by optimizing frequently used instructional designs, such as lectures. Guided by neuroscientific literature, we designed a spaced learning lecture in which the educator repeats the to-be-learned information using short temporal intervals. We investigated if this modified instructional design could enhance students' retention. Materials and methods: Second-year medic...
Abstract
Cited 8 times since 2020 (1.7 per year)
source: EuropePMC
eLife,
Volume 9, 8 2 2020, Pages e55921
Self-restoration of cardiac excitation rhythm by anti-arrhythmic ion channel gating.
Majumder R, De Coster T, Kudryashova N, Verkerk AO, Kazbanov IV, Ördög B, Harlaar N, Wilders R, de Vries AA, Ypey DL, Panfilov AV, Pijnappels DA
Homeostatic regulation protects organisms against hazardous physiological changes. However, such regulation is limited in certain organs and associated biological processes. For example, the heart fails to self-restore its normal electrical activity once disturbed, as with sustained arrhythmias. Here we present proof-of-concept of a biological self-restoring system that allows automatic detection and correction of such abnormal excitation rhythms. For the heart, its realization involves the inte...
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 110, Issue 6, 7 1 2020, Pages 2062-2069
Mechanical Mitral Valve Replacement: A Multicenter Study of Outcomes With Use of 15- to 17-mm Prostheses.
IJsselhof RJ, Slieker MG, Gauvreau K, Muter A, Marx GR, Hazekamp MG, Accord R, van Wetten H, van Leeuwen W, Haas F, Schoof PH, Nathan M
Background: The aim of this study was to evaluate early and mid-term outcomes (mortality and prosthetic valve reintervention) after mitral valve replacement with 15- to 17-mm mechanical prostheses. Methods: A multicenter, retrospective cohort study was performed among patients who underwent mitral valve replacement with a 15- to 17-mm mechanical prosthesis at 6 congenital cardiac centers: 5 in The Netherlands and 1 in the United States. Baseline, operative, and follow-up data were evaluated. Res...
Abstract
Cited 6 times since 2020 (1.3 per year)
source: EuropePMC
Kidney international reports,
Volume 5, Issue 8, 5 1 2020, Pages 1327-1332
A Randomized Trial of Liposomal Prednisolone (LIPMAT) to Enhance Radiocephalic Fistula Maturation: A Pilot Study.
Voorzaat BM, van der Bogt KEA, Bezhaeva T, van Schaik J, Eefting D, van der Putten K, van Nieuwenhuizen RC, Groeneveld JO, Hoogeveen EK, van der Meer IM, Statius van Eps RG, Vogt L, Huisman L, Gabreëls BATF, Boom H, Verburgh CA, Boon D, Metselaar JM, Weijmer MC, Rotmans JI
Abstract
Journal of electrocardiology,
Volume 61, 5 1 2020, Pages 141-146
Lack of diagnostic utility of the ECG-derived ventricular gradient in patients with suspected acute pulmonary embolism.
Meijer FMM, Hendriks SV, Huisman MV, van der Hulle T, Swenne CA, Kies P, Jongbloed MRM, Egorova AD, Vliegen HW, Klok FA
Introduction: The YEARS algorithm was successfully developed to reduce the number of computed tomography pulmonary angiography (CTPA) investigations in the diagnostic management of patients with suspected pulmonary embolism (PE), although half of patients still needed to be referred for CTPA. We hypothesized that ECG derived ventricular gradient optimized for right ventricular pressure overload (VG-RVPO), an easy to use tool for detecting PE-induced pulmonary hypertension (PH), may further impro...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Circulation reports,
Volume 2, Issue 7, 5 1 2020, Pages 364-371
Effect of Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve on Physicians' Clinical Behavior - Differences Between Sites With and Without Appropriate Use Criteria as Designated by the Japanese Reimbursement System.
Matsuo H, Kawasaki T, Amano T, Kawase Y, Sobue Y, Kondo T, Morino Y, Yoda S, Sakamoto T, Ito H, Shite J, Otake H, Tanaka N, Terashima M, Kadota K, Patel MR, Nieman K, Rogers C, Norgaard BL, Bax JJ, Chinnaiyan KM, Berman DS, Fairbairn TA, Hurwitz Koweek LM, Leipsic J, Akasaka T
Background: Coronary computed tomography angiography (CCTA)-derived fractional flow reserve (FFRCT) is an established tool for identifying lesion-specific ischemia that is now approved for use by the Japanese insurance system. However, current clinical reimbursement is strictly limited to institutions with designated appropriate use criteria (AUC). This study assessed differences in physicians' behavior (e.g., use and interpretation of FFRCT, final management) according to Japanese AUC and...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 68, 2 1 2020, Pages 159-165
Identifying Factors Influencing Decision Making in Patients Diagnosed with Carotid Body Tumors: An Exploratory Study.
Alimohamad H, Yilmaz D, Hamming JF, Schepers A
Background: Carotid body tumors (CBTs) are rare highly vascularized and slow enlarging tumors arising from the paraganglionic tissue at the carotid bifurcation. Main treatment options for CBTs are surgical resection or "wait and scan" strategy. The choice for either strategy may be equally good medically in many patients. A structured "shared decision making" (SDM) might be helpful for guiding patients. Objectives: To develop an SDM strategy for the surgical treatment, we aim...
Abstract
Cited 41 times since 2020 (8.6 per year)
source: EuropePMC
JAMA cardiology,
Volume 5, Issue 6, 1 1 2020, Pages 709-713
An Exploratory Analysis of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition and Aortic Stenosis in the FOURIER Trial.
Bergmark BA, O'Donoghue ML, Murphy SA, Kuder JF, Ezhov MV, Ceška R, Gouni-Berthold I, Jensen HK, Tokgozoglu SL, Mach F, Huber K, Gaciong Z, Lewis BS, Schiele F, Jukema JW, Pedersen TR, Giugliano RP, Sabatine MS
Importance: Despite recent advances in treatment of severe aortic valve stenosis (AS), AS remains a life-threatening condition with no proven disease-modifying therapy. Low-density lipoprotein cholesterol (LDL-C) and lipoprotein(a) (Lp[a]) have been implicated in the pathobiology of AS. The proprotein convertase subtilisin/kexin type 9 inhibitor evolocumab reduces circulating LDL-C concentrations by 50% to 60% and Lp(a) by 20% to 30%. Objective: To determine whether evolocumab reduces the risk o...
Abstract
Cited 16 times since 2020 (3.4 per year)
source: EuropePMC
Bioinformatics (Oxford, England),
Volume 36, Issue 12, 1 1 2020, Pages 3874-3876
gplas: a comprehensive tool for plasmid analysis using short-read graphs.
Arredondo-Alonso S, Bootsma M, Hein Y, Rogers MRC, Corander J, Willems RJL, Schürch AC
Summary: Plasmids can horizontally transmit genetic traits, enabling rapid bacterial adaptation to new environments and hosts. Short-read whole-genome sequencing data are often applied to large-scale bacterial comparative genomics projects but the reconstruction of plasmids from these data is facing severe limitations, such as the inability to distinguish plasmids from each other in a bacterial genome. We developed gplas, a new approach to reliably separate plasmid contigs into discrete componen...
Abstract
Cited 29 times since 2020 (6.1 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 24, 1 1 2020, Pages 2248-2258
Effect of alirocumab on cardiovascular outcomes after acute coronary syndromes according to age: an ODYSSEY OUTCOMES trial analysis.
Sinnaeve PR, Schwartz GG, Wojdyla DM, Alings M, Bhatt DL, Bittner VA, Chiang CE, Correa Flores RM, Diaz R, Dorobantu M, Goodman SG, Jukema JW, Kim YU, Pordy R, Roe MT, Sy RG, Szarek M, White HD, Zeiher AM, Steg PG, ODYSSEY OUTCOMES Investigators
Aims: Lowering low-density lipoprotein cholesterol (LDL-C) reduces cardiovascular risk irrespective of age, but the evidence is less strong for older patients. Methods and results: This prespecified analysis from ODYSSEY OUTCOMES compared the effect of alirocumab vs. placebo in 18 924 patients with recent acute coronary syndrome (ACS) according to age. We examined the effect of assigned treatment on occurrence of the primary study outcome, a composite of coronary heart disease death, myocardial...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 30, Issue 6, 1 1 2020, Pages 846-853
Treatment and outcome of plastic bronchitis in single ventricle patients: a systematic review.
Harteveld LM, Blom NA, Hazekamp MG, Ten Harkel ADJ
Plastic bronchitis (PB) is a life-threatening complication in single ventricle (SV) patients of which the exact pathophysiology, outcome and optimal treatment are still unclear. This study aims to systematically review the literature to give insight into the characteristics, outcome and management options of SV patients with PB. A systematic review was conducted, using the electronic database PubMed to find records published up to August 2018, describing SV patients and PB in which characteristi...
Abstract
Cited 12 times since 2020 (2.5 per year)
source: EuropePMC
Progress in cardiovascular diseases,
Volume 63, Issue 4, 30 5 2020, Pages 434-441
Clinical presentation and outcomes of adults with bicuspid aortic valves: 2020 update.
Yang LT, Tribouilloy C, Masri A, Bax JJ, Delgado V, Girdauskas E, Evangelista A, Sundt TM, Svensson LG, Enriquez-Sarano M, Michelena HI
The congenital bicuspid aortic valve (BAV) is a heterogeneous condition that is better understood considering 3 types of valvulo-aortopathy presentations: A typical-presentation valvulo-aortopathy, a complex-presentation valvulo-aortopathy and an uncomplicated/undiagnosed-presentation. The burden of BAV-related complications has been elucidated in patients with the typical-presentation valvulo-aortopathy and is discussed in this review. These patients enjoy an overall normal expected long-term s...
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
Forensic science international,
Volume 313, 29 5 2020, Pages 110344
Chemical attribution of the homemade explosive ETN - Part II: Isotope ratio mass spectrometry analysis of ETN and its precursors.
Bezemer K, McLennan L, Hessels R, Schoorl J, van den Elshout J, van der Heijden A, Hulsbergen A, Koeberg M, Busby T, Yevdokimov A, de Rijke E, Schoenmakers P, Smith J, Oxley J, van Asten A
In this follow-up study the collaboration between two research groups from the USA and the Netherlands was continued to expand the framework of chemical attribution for the homemade explosive erythritol tetranitrate (ETN). Isotope ratio mass spectrometry (IRMS) analysis was performed to predict possible links between ETN samples and its precursors. Carbon, nitrogen, hydrogen and oxygen isotope ratios were determined for a wide variety of precursor sources and for ETN samples that were prepared w...
Abstract
Cardiovascular revascularization medicine : including molecular interventions,
Volume 21, Issue 12, 29 5 2020, Pages 1493-1499
Association Between Flow Impairment in Dominant Coronary Atrial Branches and Atrial Arrhythmias in Patients With ST-Segment Elevation Myocardial Infarction.
Montero Cabezas JM, Abou R, Goedemans L, Ajmone Marsan N, Bax JJ, Delgado V
Objectives: The impact of atrial ischemia in the occurrence of atrial arrhythmias may vary based on the amount of jeopardized myocardium. We sought to determine the association between coronary flow impairment in dominant coronary atrial branches (CAB) and atrial arrhythmias at 1-year follow-up in ST-segment elevation myocardial infarction (STEMI) patients. Methods: Patients with STEMI involving the right or circumflex coronary artery were included. Dominant CAB was defined as the most developed...
Abstract
Cited 3 times since 2020 (0.6 per year)
source: EuropePMC
Journal of aging and health,
Volume 32, Issue 9, 27 4 2020, Pages 1267-1274
Association of High-Density Lipoprotein Cholesterol With Cognitive Function: Findings From the PROspective Study of Pravastatin in the Elderly at Risk.
Grasset L, Smit RAJ, Caunca MR, Elfassy T, Odden MC, van der Grond J, van Buchem MA, Stott DJ, Sattar N, Trompet S, Jukema JW, Zeki Al Hazzouri A
Objective: We aimed to examine whether variability in high-density lipoprotein cholesterol (HDL-c) over time was associated with cognitive function. Method: We conducted a post hoc analysis of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) trial. Our sample included 4,428 participants with at least two repeated HDL-c measures between Months 3 and 24 postbaseline and with cognitive assessments at Month 30. HDL-c variability was defined as the intraindividual standard deviat...
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
European journal of orthopaedic surgery & traumatology : orthopedie traumatologie,
Volume 30, Issue 8, 26 4 2020, Pages 1357-1362
Long-term follow-up of distal radius fractures, an evaluation of the current guideline: the relation between malunion, osteoarthritis and functional outcome.
Visser D, Mathijssen NMC, van Outeren MV, Colaris JW, de Vries MR, Kraan GA
Background: Last decades there is an increased tendency of performing surgery on displaced distal radius fractures. However, it is unclear whether this affects the development of osteoarthritis. This study aims to determine the relation between anatomical position, radiological osteoarthritis and functional outcome of the elderly wrist, 10-15 years after a distal radius fracture. Patients and methods: 173 patients between the age of 50 and 70 at time of trauma were included in this retrospective...
Abstract
Cited 21 times since 2020 (4.4 per year)
source: EuropePMC
Critical care (London, England),
Volume 24, Issue 1, 26 4 2020, Pages 263
COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients.
Kox M, Frenzel T, Schouten J, van de Veerdonk FL, Koenen HJPM, Pickkers P, , on behalf of the RCI-COVID-19 study group
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 36, Issue 9, 25 4 2020, Pages 1771-1780
Left ventricular global longitudinal strain in bicupsid aortic valve patients: head-to-head comparison between computed tomography, 4D flow cardiovascular magnetic resonance and speckle-tracking echocardiography.
van den Hoven AT, Yilmazer S, Chelu RG, van Grootel RWJ, Minderhoud SCS, Bons LR, van Berendoncks AM, Duijnhouwer AL, Siebelink HJ, van den Bosch AE, Budde RPJ, Roos-Hesselink JW, Hirsch A
Left ventricular global longitudinal strain (LVGLS) analysis is a sensitive measurement of myocardial deformation most often done using speckle-tracking transthoracic echocardiography (TTE). We propose a novel approach to measure LVGLS using feature-tracking software on the magnitude dataset of 4D flow cardiovascular magnetic resonance (CMR) and compare it to dynamic computed tomography (CT) and speckle tracking TTE derived measurements. In this prospective cohort study 59 consecutive adult pati...
Abstract
Cited 7 times since 2020 (1.5 per year)
source: EuropePMC
PloS one,
Volume 15, Issue 5, 15 3 2020, Pages e0228478
Pulmonary ductal coarctation and left pulmonary artery interruption; pathology and role of neural crest and second heart field during development.
Gittenberger-de Groot AC, Peterson JC, Wisse LJ, Roest AAW, Poelmann RE, Bökenkamp R, Elzenga NJ, Hazekamp M, Bartelings MM, Jongbloed MRM, DeRuiter MC
Objectives: In congenital heart malformations with pulmonary stenosis to atresia an abnormal lateral ductus arteriosus to left pulmonary artery connection can lead to a localised narrowing (pulmonary ductal coarctation) or even interruption We investigated embryonic remodelling and pathogenesis of this area. Material and methods: Normal development was studied in WntCre reporter mice (E10.0-12.5) for neural crest cells and Nkx2.5 immunostaining for second heart field cells. Data were compared to...
Abstract
