Research

Publications

Below you can find a list of our published research.

6128 results

Cited 1 times since 2018 (0.2 per year) source: EuropePMC

International journal of integrated care, Volume 18, Issue 4, 31 5 2019, Pages 15 The Integrated Dyspnea Clinic: An Evaluation of Efficiency. Rietbroek MV, Slats AM, Kiès P, de Grooth GJ, Chavannes NH, Taube C, Bonten TN

Introduction: Dyspnea is a common complaint and in 70 to 90% the origin is pulmonary or cardiovascular. However, referral to the "wrong" specialism could result in diagnostic- and treatment delay. Integrated care by a cardiologist and a pulmonologist could improve this. The aim of the present study was to evaluate whether integrated care for patients with dyspnea is more efficient and effective than regular care. Methods: Consecutive patients (n = 235) seen at our dyspnea clinic after... Abstract

Cited 10 times since 2018 (1.6 per year) source: EuropePMC

JACC. Clinical electrophysiology, Volume 5, Issue 3, 26 4 2018, Pages 318-326 Incidence and Clinical Significance of Cerebral Embolism During Atrial Fibrillation Ablation With Duty-Cycled Phased-Radiofrequency Versus Cooled-Radiofrequency: A Randomized Controlled Trial. Keçe F, Bruggemans EF, de Riva M, Alizadeh Dehnavi R, Wijnmaalen AP, Meulman TJ, Brugman JA, Rooijmans AM, van Buchem MA, Middelkoop HA, Eikenboom J, Schalij MJ, Zeppenfeld K, Trines SA

Objectives: The purpose of this study was to randomly compare the incidence of asymptomatic cerebral embolism (ACE) between the second-generation pulmonary vein ablation catheter (PVAC Gold) and the irrigated Thermocool catheter. Background: Pulmonary vein isolation (PVI) with the PVAC is associated with ACE. The PVAC Gold was designed to avoid this complication. Methods: Patients with paroxysmal atrial fibrillation were randomized 1:1 to PVI with the PVAC Gold or Thermocool catheter. Cerebral m... Abstract

Cited 19 times since 2018 (3.1 per year) source: EuropePMC

PLoS computational biology, Volume 14, Issue 12, 20 3 2018, Pages e1006637 Dynamical anchoring of distant arrhythmia sources by fibrotic regions via restructuring of the activation pattern. Vandersickel N, Watanabe M, Tao Q, Fostier J, Zeppenfeld K, Panfilov AV

Rotors are functional reentry sources identified in clinically relevant cardiac arrhythmias, such as ventricular and atrial fibrillation. Ablation targeting rotor sites has resulted in arrhythmia termination. Recent clinical, experimental and modelling studies demonstrate that rotors are often anchored around fibrotic scars or regions with increased fibrosis. However, the mechanisms leading to abundance of rotors at these locations are not clear. The current study explores the hypothesis whether... Abstract

Cited 4 times since 2018 (0.6 per year) source: EuropePMC

Injury, Volume 50, Issue 2, 19 3 2018, Pages 286-291 Migration of Aortic Occlusion Balloons in an in vitro model of the human circulation. Borger van der Burg BLS, Van Schaik J, Brouwers JJWM, Wong CY, Rasmussen TE, Hamming JF, Hoencamp R

Background: Aortic Occlusion Balloons (AOB) are used for hemorrhage control in hemodynamically unstable patients. Stability of an AOB is essential for reliable aortic occlusion. The primary aim of this study is to determine whether different types of AOB migrate after total, intermittent or partial occlusion in a porcine aorta positioned in an in vitro model. Materials and methods: A porcine thoracic aortic section was positioned in a model of the human circulation. Primary and secondary migrati... Abstract

Cited 24 times since 2018 (3.9 per year) source: EuropePMC

The Journal of pediatrics, Volume 207, 18 3 2018, Pages 109-116.e2 Low Cerebral Oxygenation in Preterm Infants Is Associated with Adverse Neurodevelopmental Outcome. Alderliesten T, van Bel F, van der Aa NE, Steendijk P, van Haastert IC, de Vries LS, Groenendaal F, Lemmers P

Objective: To assess whether high and low levels of cerebral oxygenation (regional cerebral oxygenation [rScO2]) in infants born at Abstract

Cited 16 times since 2018 (2.6 per year) source: EuropePMC

Journal of cardiovascular computed tomography, Volume 13, Issue 2, 17 3 2018, Pages 142-147 Longitudinal assessment of coronary plaque volume change related to glycemic status using serial coronary computed tomography angiography: A PARADIGM (Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography Imaging) substudy. Won KB, Lee SE, Lee BK, Park HB, Heo R, Rizvi A, Lin FY, Kumar A, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, Leipsic JA, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Raff GL, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Chang HJ

Background: Data on the impact of glycemic status on coronary plaque progression have been limited. This study evaluated the association between glycemic status and coronary plaque volume change (PVC) using coronary computed tomography angiography (CCTA). Methods: A total of 1296 subjects (61 ± 9, 56.9% male) who underwent serial CCTA with available glycemic status were enrolled and analyzed from the Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PA... Abstract

Cited 11 times since 2018 (1.8 per year) source: EuropePMC

PloS one, Volume 13, Issue 12, 12 2 2018, Pages e0207194 Usefulness of baseline statin therapy in non-obstructive coronary artery disease by coronary computed tomographic angiography: From the CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) study. Cho YK, Nam CW, Koo BK, Schulman-Marcus J, Hartaigh BÓ, Gransar H, Lu Y, Achenbach S, Al-Mallah M, Andreini D, Bax JJ, Budoff MJ, Cademartiri F, Callister TQ, Chang HJ, Chinnaiyan K, Chow BJW, Cury RC, Delago A, Feuchtner G, Hadamitzky M, Hausleiter J, Kaufmann PA, Kim YJ, Leipsic J, Maffei E, Marques H, Pontone G, Raff GL, Rubinshtein R, Shaw LJ, Villines TC, Berman DS, Jones EC, Peña JM, Lin FY, Min JK

Background: The extent to which the presence and extent of subclinical atherosclerosis by coronary computed tomography angiography influences a potential mortality benefit of statin is unknown. We evaluated the relationship between statin therapy, mortality, and subclinical atherosclerosis. Methods: In the CONFIRM study, patients with normal or non-obstructive plaque ( Abstract

Cited 10 times since 2018 (1.6 per year) source: EuropePMC

Pediatric cardiology, Volume 40, Issue 3, 11 2 2018, Pages 585-594 Risk of Clinically Relevant Pericardial Effusion After Pediatric Cardiac Surgery. Adrichem R, Le Cessie S, Hazekamp MG, Van Dam NAM, Blom NA, Rammeloo LAJ, Filippini LHPM, Kuipers IM, Ten Harkel ADJ, Roest AAW

Pericardial effusion (PE) after pediatric cardiac surgery is common. Because of the lack of a uniform classification of the presence and severity of PE, we evaluated PE altering clinical management: clinically relevant PE. Risk factors for clinically relevant PE were studied. After cardiac surgery, children were followed until 1 month after surgery. Preoperative variables were studied in the complete cohort. Perioperative and postoperative variables were studied in a case-control manner. Patient... Abstract

Cited 1 times since 2018 (0.2 per year) source: EuropePMC

Seminars in thoracic and cardiovascular surgery, Volume 31, Issue 3, 8 2 2018, Pages 383-391 Developing a Quality Standard for Verbal Communication During CABG Procedures. de Lind van Wijngaarden RAF, Siregar S, Legué J, Fraaije A, Abbas A, Dankelman J, Klautz RJM

Verbal communication during coronary artery bypass graft (CABG) procedures is essential for safe and efficient cardiac surgery, yet sensitive to failure due to a current lack of standardization. The goal of this study was to improve communication during CABG by identifying critical items in verbal interaction between surgeons, anesthetists, and perfusionists. Based on 6 video recordings, a list was assembled containing items of communication in CABG procedures. Personal interviews and a consecut... Abstract

Cited 4 times since 2018 (0.6 per year) source: EuropePMC

The Canadian journal of cardiology, Volume 35, Issue 4, 7 1 2018, Pages 438-445 The Natural and Unnatural History of Congenital Aortic Arch Abnormalities Evaluated in an Adult Survival Cohort. Lodeweges JE, Dikkers FG, Mulder BJM, Roos-Hesselink JW, Vliegen HW, van Dijk APJ, Sieswerda GT, Konings TC, Berger RMF, Slebos DJ, Ebels T, van Melle JP

Background: This study describes the different types of congenital vascular rings according to their anatomy, symptoms, and age at clinical onset and reports the surgical outcomes. Methods: A retrospective observational database study was conducted, reviewing the medical charts of 69 adult survivors with a history of a vascular ring, identified from the Dutch Congenital Cor vitia database. Results: Median age at presentation was 8.5 years (0-53.0 years). Thirty patients (43.5%) had a "left... Abstract

Cited 3 times since 2018 (0.5 per year) source: EuropePMC

Injury, Volume 50, Issue 5, 6 1 2018, Pages 1036-1041 Identification of thoracic injuries by emergency medical services providers among trauma patients. van Rein EAJ, Lokerman RD, van der Sluijs R, Hjortnaes J, Lichtveld RA, Leenen LPH, van Heijl M

Introduction: Severe thoracic injuries are time sensitive and adequate triage to a facility with a high-level of trauma care is crucial. The emergency medical services (EMS) providers are required to identify patients with a severe thoracic injury to transport the patient to the right hospital. However, identifying these patients on-scene is difficult. The accuracy of prehospital assessment of potential thoracic injury by EMS providers of the ground ambulances is unknown. Therefore, the aim of t... Abstract

Cited 87 times since 2018 (13.9 per year) source: EuropePMC

Nature communications, Volume 9, Issue 1, 3 1 2018, Pages 5141 GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Franceschini N, Giambartolomei C, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, Nolte IM, Lu L, Scholz M, Sargurupremraj M, Pitkänen N, Franzén O, Joshi PK, Noordam R, Marioni RE, Hwang SJ, Musani SK, Schminke U, Palmas W, Isaacs A, Correa A, Zonderman AB, Hofman A, Teumer A, Cox AJ, Uitterlinden AG, Wong A, Smit AJ, Newman AB, Britton A, Ruusalepp A, Sennblad B, Hedblad B, Pasaniuc B, Penninx BW, Langefeld CD, Wassel CL, Tzourio C, Fava C, Baldassarre D, O'Leary DH, Teupser D, Kuh D, Tremoli E, Mannarino E, Grossi E, Boerwinkle E, Schadt EE, Ingelsson E, Veglia F, Rivadeneira F, Beutner F, Chauhan G, Heiss G, Snieder H, Campbell H, Völzke H, Markus HS, Deary IJ, Jukema JW, de Graaf J, Price J, Pott J, Hopewell JC, Liang J, Thiery J, Engmann J, Gertow K, Rice K, Taylor KD, Dhana K, Kiemeney LALM, Lind L, Raffield LM, Launer LJ, Holdt LM, Dörr M, Dichgans M, Traylor M, Sitzer M, Kumari M, Kivimaki M, Nalls MA, Mela

Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart disease (CHD). Here, we undertake meta-analyses of genome-wide association studies (GWAS) in 71,128 individuals for cIMT, and 48,434 individuals for carotid plaque traits. We identify eight novel susceptibility loci for cIMT, one independent association at the previously-identified PINX1 locus, and one novel locus for carotid plaque. Coloc... Abstract

Cited 16 times since 2018 (2.6 per year) source: EuropePMC

Cardiovascular research, Volume 114, Issue 14, 1 1 2018, Pages 1848-1859 Generation and primary characterization of iAM-1, a versatile new line of conditionally immortalized atrial myocytes with preserved cardiomyogenic differentiation capacity. Liu J, Volkers L, Jangsangthong W, Bart CI, Engels MC, Zhou G, Schalij MJ, Ypey DL, Pijnappels DA, de Vries AAF

Aims: The generation of homogeneous cardiomyocyte populations from fresh tissue or stem cells is laborious and costly. A potential solution to this problem would be to establish lines of immortalized cardiomyocytes. However, as proliferation and (terminal) differentiation of cardiomyocytes are mutually exclusive processes, their permanent immortalization causes loss of electrical and mechanical functions. We therefore aimed at developing conditionally immortalized atrial myocyte (iAM) lines allo... Abstract

Cited 15 times since 2018 (2.4 per year) source: EuropePMC

Nature genetics, Volume 50, Issue 12, 1 1 2018, Pages 1755 Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, Giri A, Velez Edwards DR, Sun YV, Cho K, Gaziano JM, Wilson PWF, Tsao PS, Kovesdy CP, Esko T, Mägi R, Milani L, Almgren P, Boutin T, Debette S, Ding J, Giulianini F, Holliday EG, Jackson AU, Li-Gao R, Lin WY, Luan J, Mangino M, Oldmeadow C, Prins BP, Qian Y, Sargurupremraj M, Shah N, Surendran P, Thériault S, Verweij N, Willems SM, Zhao JH, Amouyel P, Connell J, de Mutsert R, Doney ASF, Farrall M, Menni C, Morris AD, Noordam R, Paré G, Poulter NR, Shields DC, Stanton A, Thom S, Abecasis G, Amin N, Arking DE, Ayers KL, Barbieri CM, Batini C, Bis JC, Blake T, Bochud M, Boehnke M, Boerwinkle E, Boomsma DI, Bottinger EP, Braund PS, Brumat M, Campbell A, Campbell H, Chakravarti A, Chambers JC, Chauhan G, Ciullo M, Cocca M, Collins F, Cordell HJ, Davies G, de Borst MH, de Geus EJ, Deary IJ, Deelen J, Del Greco M F, Demirkale CY, Dörr M, Ehret GB, El

In the version of this article originally published, the name of author Martin H. de Borst was coded incorrectly in the XML. The error has now been corrected in the HTML version of the paper. Abstract

Cited 4 times since 2018 (0.6 per year) source: EuropePMC

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 20, Issue 12, 1 1 2018, Pages 1989-1996 Electrical latency predicts the optimal left ventricular endocardial pacing site: results from a multicentre international registry. Sieniewicz BJ, Behar JM, Sohal M, Gould J, Claridge S, Porter B, Niederer S, Gamble JHP, Betts TR, Jais P, Derval N, Spragg DD, Steendijk P, van Gelder BM, Bracke FA, Rinaldi CA

Aims: The optimal site for biventricular endocardial (BIVENDO) pacing remains undefined. Acute haemodynamic response (AHR) is reproducible marker of left ventricular (LV) contractility, best expressed as the change in the maximum rate of LV pressure (LV-dp/dtmax), from a baseline state. We examined the relationship between factors known to impact LV contractility, whilst delivering BIVENDO pacing at a variety of LV endocardial (LVENDO) locations. Methods and results: We compiled a registry of ac... Abstract

Cited 1 times since 2018 (0.2 per year) source: EuropePMC

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 54, Issue 6, 1 1 2018, Pages 1147-1148 Off-pump mitral valve repair: is less really more? Tomšic A, Klautz RJM, Palmen M

Abstract

Cited 8 times since 2018 (1.3 per year) source: Scopus

European journal of preventive cardiology, Volume 26, Issue 6, 28 4 2018, Pages 606-608 BENEFIT for all: An ecosystem to facilitate sustained healthy living and reduce the burden of cardiovascular disease. Keesman M, Janssen V, Kemps H, Hollander M, Reimer WSO, Gemert-Pijnen LV, Hoes A, Kraaij W, Chavannes N, Atsma D, Kraaijenhagen R, Evers A, BENEFIT consortium

Abstract

Cited 2 times since 2018 (0.3 per year) source: EuropePMC

PloS one, Volume 13, Issue 11, 27 4 2018, Pages e0207943 Qualitative evaluation of coronary atherosclerosis in a large cohort of young and middle-aged Dutch tissue donors implies that coronary thrombo-embolic manifestations are stochastic. Lindeman JH, Hulsbos L, van den Bogaerdt AJ, Geerts M, van Gool AJ, Hamming JF, van Dijk RA, Schaapherder AF

Background and aims: With the intention to gain support for the hypothesis that incident ischemic complications of atherosclerotic disease involve a stochastic aspect, we performed a histological, qualitative evaluation of the epidemiology of coronary atherosclerotic disease in a cohort of aortic valve donors. Patients and methods: Donors (n = 695, median age 54, range 11-65 years) were dichotomized into a non-cardiovascular (non-CVD) and a cardiovascular disease death (CVD) group. Consecutive 5... Abstract

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 26, Issue 1, 20 3 2018, Pages 76-85 Multimodality imaging: Bird's eye view from The European Society of Cardiology Congress 2018 Munich, August 25-29, 2018. Delgado V, Bucciarelli-Ducci C, Gaemperli O, Maurovich-Horvat P, Bax JJ

At the European Society of Cardiology (ESC) congress of this year 2018, held in Munich from August 25th to 29th, 4594 abstracts were presented. Of those, 423 (10.8%) belonged to an imaging category. Experts in echocardiography (VD), cardiovascular magnetic resonance (CMR) (CBD), nuclear imaging (OG), and cardiac computed tomography (CT) (PMH) have selected the abstracts in their areas of expertise that were of most interest to them and are summarized in this bird's eye view from this ESC me... Abstract

Cited 1 times since 2018 (0.2 per year) source: EuropePMC

JACC. Cardiovascular imaging, Volume 12, Issue 4, 15 3 2018, Pages 759-760 Comparison of Insonation-Augmented Physical Examination With Standard Physical Examination in Detecting Severe Left-Sided Valve Disease. Argulian E, Ramirez R, Hobson S, Bavishi C, Casso Dominguez A, Selby A, Talebi S, Moreno P, Ahmadi AA, Bax JJ, Narula J

Abstract