Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6177 results
Cited 3 times since 2020 (0.6 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 21, Issue 9, 1 1 2020, Pages 959-960 An international, multicentre survey of echocardiographic abnormalities in COVID-19 patients. Ng ACT, Delgado V, Bax JJ
Cited 22 times since 2020 (4.7 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 21, Issue 9, 1 1 2020, Pages 973-980 Non-obstructive high-risk plaques increase the risk of future culprit lesions comparable to obstructive plaques without high-risk features: the ICONIC study. Ferraro RA, van Rosendael AR, Lu Y, Andreini D, Al-Mallah MH, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, de Araújo Gonçalves P, Hadamitzky M, Kim YJ, Leipsic J, Maffei E, Marques H, Plank F, Pontone G, Raff GL, Villines TC, Lee SE, Al'Aref SJ, Baskaran L, Cho I, Danad I, Gransar H, Budoff MJ, Samady H, Stone PH, Virmani R, Narula J, Berman DS, Chang HJ, Bax JJ, Min JK, Shaw LJ, Lin FY
Aims: High-risk plaque (HRP) and non-obstructive coronary artery disease independently predict adverse events, but their importance to future culprit lesions has not been resolved. We sought to determine in patients prior to confirmed acute coronary syndrome (ACS) the association between lesion percent diameter stenosis (%DS), and the absolute number and prevalence of HRP. The secondary objective was to examine the relative importance of non-obstructive HRP in future culprit lesions. Methods and... Abstract
Cited 19 times since 2020 (4.1 per year) source: EuropePMC
European heart journal, Volume 41, Issue 33, 1 1 2020, Pages 3184-3197 Leaflet immobility and thrombosis in transcatheter aortic valve replacement. Ng ACT, Holmes DR, Mack MJ, Delgado V, Makkar R, Blanke P, Leipsic JA, Leon MB, Bax JJ
Transcatheter aortic valve replacement (TAVR) has grown exponentially worldwide in the last decade. Due to the higher bleeding risks associated with oral anticoagulation and in patients undergoing TAVR, antiplatelet therapy is currently considered first-line antithrombotic treatment after TAVR. Recent studies suggest that some patients can develop subclinical transcatheter heart valve (THV) thrombosis after the procedure, whereby thrombus forms on the leaflets that can be a precursor to leaflet... Abstract
Cited 122 times since 2020 (26.3 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 76, Issue 9, 1 1 2020, Pages 1018-1030 Bicuspid Aortic Valve Morphology and Outcomes After Transcatheter Aortic Valve Replacement. Yoon SH, Kim WK, Dhoble A, Milhorini Pio S, Babaliaros V, Jilaihawi H, Pilgrim T, De Backer O, Bleiziffer S, Vincent F, Shmidt T, Butter C, Kamioka N, Eschenbach L, Renker M, Asami M, Lazkani M, Fujita B, Birs A, Barbanti M, Pershad A, Landes U, Oldemeyer B, Kitamura M, Oakley L, Ochiai T, Chakravarty T, Nakamura M, Ruile P, Deuschl F, Berman D, Modine T, Ensminger S, Kornowski R, Lange R, McCabe JM, Williams MR, Whisenant B, Delgado V, Windecker S, Van Belle E, Sondergaard L, Chevalier B, Mack M, Bax JJ, Leon MB, Makkar RR, Bicuspid Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Registry Investigators
Background: Bicuspid aortic stenosis accounts for almost 50% of patients undergoing surgical aortic valve replacement in the younger patients. Expanding the indication of transcatheter aortic valve replacement (TAVR) toward lower-risk and younger populations will lead to increased use of TAVR for patients with bicuspid aortic valve (BAV) stenosis despite the exclusion of bicuspid anatomy in all pivotal clinical trials. Objectives: This study sought to evaluate the association of BAV morphology a... Abstract
JACC. Clinical electrophysiology, Volume 6, Issue 9, 1 1 2020, Pages 1191-1192 Reply: Debating the Definition and Incidence of Isolated Cardiac Sarcoidosis. Hoogendoorn JC, Bogun FM, Tedrow UB, Stevenson WG, Zeppenfeld K
Cited 9 times since 2020 (1.9 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 22, Issue 9, 1 1 2020, Pages 1376-1383 The harm of delayed diagnosis of arrhythmogenic cardiac sarcoidosis: a case series. Hoogendoorn JC, Ninaber MK, Piers SRD, de Riva M, Grauss RW, Bogun FM, Zeppenfeld K
Aims: Cardiac sarcoidosis (CS) is a known cause of ventricular tachycardia (VT). However, an arrhythmogenic presentation may not prompt immediate comprehensive evaluation. We aimed to assess the diagnostic and disease course of patients with arrhythmogenic cardiac sarcoidosis (ACS). Methods and results: From the Leiden VT-ablation-registry, consecutive patients with CS as underlying aetiology were retrospectively included. Data on clinical presentation, time-to-diagnosis, cardiac function, and c... Abstract
Nature, Volume 585, Issue 7825, 1 1 2020, Pages E11 Author Correction: Global status and conservation potential of reef sharks. MacNeil MA, Chapman DD, Heupel M, Simpfendorfer CA, Heithaus M, Meekan M, Harvey E, Goetze J, Kiszka J, Bond ME, Currey-Randall LM, Speed CW, Sherman CS, Rees MJ, Udyawer V, Flowers KI, Clementi G, Valentin-Albanese J, Gorham T, Adam MS, Ali K, Pina-Amargós F, Angulo-Valdés JA, Asher J, Barcia LG, Beaufort O, Benjamin C, Bernard ATF, Berumen ML, Bierwagen S, Bonnema E, Bown RMK, Bradley D, Brooks E, Brown JJ, Buddo D, Burke P, Cáceres C, Cardeñosa D, Carrier JC, Caselle JE, Charloo V, Claverie T, Clua E, Cochran JEM, Cook N, Cramp J, D'Alberto B, de Graaf M, Dornhege M, Estep A, Fanovich L, Farabaugh NF, Fernando D, Flam AL, Floros C, Fourqurean V, Garla R, Gastrich K, George L, Graham R, Guttridge T, Hardenstine RS, Heck S, Henderson AC, Hertler H, Hueter R, Johnson M, Jupiter S, Kasana D, Kessel ST, Kiilu B, Kirata T, Kuguru B, Kyne F, Langlois T, Lédée EJI, Lindfield S, Luna-Acosta A, Maggs J, Manjaji-Matsumoto BM, Marshall A, Matich P, McCombs E, McLean D, Meggs L, Moore S, Mukherji S, Murray R, Kaimuddin
An Amendment to this paper has been published and can be accessed via a link at the top of the paper. Abstract
JACC. Heart failure, Volume 8, Issue 9, 1 1 2020, Pages 784-785 Reply: Assessment of Right Heart Function in Secondary Tricuspid Regurgitation. Dietz MF, Prihadi EA, van der Bijl P, Ajmone Marsan N, Delgado V, Bax JJ
Cited 14 times since 2020 (3 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 58, Issue 3, 1 1 2020, Pages 544-550 A structured approach to native mitral valve infective endocarditis: Is repair better than replacement? Defauw RJ, Tomšič A, van Brakel TJ, Marsan NA, Klautz RJM, Palmen M
Objectives: Mitral valve repair in native active infective endocarditis is technically challenging. The survival benefit over valve replacement is poorly established and possibly absent because of the high risk of repair failure and reoperation. In this study, we explore the results of our structured approach in these patients. Methods: Between January 2000 and January 2017, 149 patients underwent surgery for native mitral infective endocarditis. Among them, 97 (66%) patients underwent valve rep... Abstract
Cited 155 times since 2020 (33.3 per year) source: EuropePMC
The New England journal of medicine, Volume 383, Issue 15, 30 5 2020, Pages 1447-1457 Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation. Brouwer J, Nijenhuis VJ, Delewi R, Hermanides RS, Holvoet W, Dubois CLF, Frambach P, De Bruyne B, van Houwelingen GK, Van Der Heyden JAS, Toušek P, van der Kley F, Buysschaert I, Schotborgh CE, Ferdinande B, van der Harst P, Roosen J, Peper J, Thielen FWF, Veenstra L, Chan Pin Yin DRPP, Swaans MJ, Rensing BJWM, van 't Hof AWJ, Timmers L, Kelder JC, Stella PR, Baan J, Ten Berg JM
Background: The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has not been well studied. Methods: In a randomized, controlled trial, we assigned a subgroup of patients who were undergoing TAVI and did not have an indication for long-term anticoagulation, in a 1:1 ratio, to receive aspirin alone or aspirin plus clopidogr... Abstract
Cited 13 times since 2020 (2.8 per year) source: EuropePMC
The American journal of cardiology, Volume 135, 28 4 2020, Pages 84-90 Prognostic Implications of Significant Isolated Tricuspid Regurgitation in Patients With Atrial Fibrillation Without Left-Sided Heart Disease or Pulmonary Hypertension. Dietz MF, Goedemans L, Vo NM, Prihadi EA, van der Bijl P, Gersh BJ, Ajmone Marsan N, Delgado V, Bax JJ
The prognostic impact of isolated tricuspid regurgitation (TR) in patients with atrial fibrillation (AF) has not been investigated. The purpose of this study was to investigate the prognostic implications of significant isolated TR in AF patients without left-sided heart disease, pulmonary hypertension, or primary structural abnormalities of the tricuspid valve. A total of 63 AF patients with moderate and severe TR were matched for age and gender to 116 AF patients without significant TR. Patien... Abstract
Cited 37 times since 2020 (7.9 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 13, Issue 12, 26 4 2020, Pages 2576-2587 Sex Differences in Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve: Lessons From ADVANCE. Fairbairn TA, Dobson R, Hurwitz-Koweek L, Matsuo H, Norgaard BL, Rønnow Sand NP, Nieman K, Bax JJ, Pontone G, Raff G, Chinnaiyan KM, Rabbat M, Amano T, Kawasaki T, Akasaka T, Kitabata H, Binukrishnan S, Rogers C, Berman D, Patel MR, Douglas PS, Leipsic J
Objectives: This study is to determine the management and clinical outcomes of patients investigated with coronary computed tomography angiography (CCTA)-derived fractional flow reserve (FFRCT) according to sex. Background: Women are underdiagnosed with conventional ischemia testing, have lower rates of obstructive coronary artery disease (CAD) at invasive coronary angiography (ICA), yet higher mortality compared to men. Whether FFRCT improves sex-based patient management decisions compared to C... Abstract
Cited 5 times since 2020 (1.1 per year) source: EuropePMC
BMJ open, Volume 10, Issue 8, 24 4 2020, Pages e036220 Design and rationale of DUTCH-AF: a prospective nationwide registry programme and observational study on long-term oral antithrombotic treatment in patients with atrial fibrillation. Chu G, Seelig J, Trinks-Roerdink EM, van Alem AP, Alings M, van den Bemt B, Boersma LV, Brouwer MA, Cannegieter SC, Ten Cate H, Kirchhof CJ, Crijns HJ, van Dijk EJ, Elvan A, van Gelder IC, de Groot JR, den Hartog FR, de Jong JS, de Jong S, Klok FA, Lenderink T, Luermans JG, Meeder JG, Pisters R, Polak P, Rienstra M, Smeets F, Tahapary GJ, Theunissen L, Tieleman RG, Trines SA, van der Voort P, Geersing GJ, Rutten FH, Hemels ME, Huisman MV
Introduction: Anticoagulation therapy is pivotal in the management of stroke prevention in atrial fibrillation (AF). Prospective registries, containing longitudinal data are lacking with detailed information on anticoagulant therapy, treatment adherence and AF-related adverse events in practice-based patient cohorts, in particular for non-vitamin K oral anticoagulants (NOAC). With the creation of DUTCH-AF, a nationwide longitudinal AF registry, we aim to provide clinical data and answer question... Abstract
Nederlands tijdschrift voor geneeskunde, Volume 164, 20 3 2020, Pages D5241 [Investigation into medical disciplinary law critically examined]. Hamming JF
There is a suggestion that the medical disciplinary committees (MDC) in the Netherlands are making more severe rulings on medical professionals. In a 10-year analysis of MDC rulings, it appears that complaints made by patients are more frequently being judged to be well-founded, and that the measures being taken are more severe. The authors conclude that there is a numerical basis for the increasing severity of the rulings. However, a numerical trend as such does not constitute proof of this, as... Abstract
Cited 20 times since 2020 (4.3 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 13, Issue 11, 19 3 2020, Pages 2386-2396 Sex Differences in Compositional Plaque Volume Progression in Patients With Coronary Artery Disease. Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Shin S, Stone PH, Samady H, Virmani R, Narula J, Berman DS, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ
Objectives: This study sought to explore sex-based differences in total and compositional plaque volume (PV) progression. Background: It is unclear whether sex has an impact on PV progression in patients with coronary artery disease (CAD). Methods: The study analyzed a prospective multinational registry of consecutive patients with suspected CAD who underwent 2 or more clinically indicated coronary computed tomography angiography (CTA) at ≥2-year intervals. Total and compositional PV at baseline... Abstract
Cited 15 times since 2020 (3.2 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 14, Issue 4, 19 3 2020, Pages 730-739 Regurgitant Volume/Left Ventricular End-Diastolic Volume Ratio: Prognostic Value in Patients With Secondary Mitral Regurgitation. Namazi F, van der Bijl P, Fortuni F, Mertens BJA, Kamperidis V, van Wijngaarden SE, Stone GW, Narula J, Ajmone Marsan N, Vahanian A, Delgado V, Bax JJ
Objectives: The purpose of this study was to investigate the prognostic implications of the ratio of mitral regurgitant volume (RVol) to left ventricular (LV) end-diastolic volume (EDV) in patients with significant secondary mitral regurgitation (MR). Background: Quantification of secondary MR remains challenging, and its severity can be over- or underestimated when using the proximal isovelocity surface area method, which does not take LV volume into account. This limitation can be addressed by... Abstract
Cited 1 times since 2020 (0.2 per year) source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Volume 97, Issue 3, 18 3 2020, Pages 488-492 Reverse remodeling after percutaneous transluminal septal myocardial ablation in severe but asymptomatic LVOT obstruction (RASTA) study: Rationale and design of transcatheter septal reduction in asymptomatic patients with severe hypertrophic obstructive cardiomyopathy. Arslan F, Akdim F, Ten Berg JM
Objectives: The aim of this study is to evaluate the impact of percutaneous transluminal septal myocardial ablation (PTSMA) on remodeling in asymptomatic patients with hypertrophic obstructive cardiomyopathy (HOCM) and severe left ventricular outflow tract (LVOT) obstruction. Background: Symptoms justify invasive treatment in HOCM patients with LVOT obstruction. Adverse structural and functional changes (remodeling) in the heart occur preceding heart failure and sudden cardiac death. Early invas... Abstract
Cited 12 times since 2020 (2.6 per year) source: EuropePMC
The American journal of cardiology, Volume 134, 15 3 2020, Pages 116-122 Comparison of the Usefulness of Strain Imaging by Echocardiography Versus Computed Tomography to Detect Right Ventricular Systolic Dysfunction in Patients With Significant Secondary Tricuspid Regurgitation. Hirasawa K, van Rosendael PJ, Dietz MF, Ajmone Marsan N, Delgado V, Bax JJ
Assessment of right ventricular (RV) systolic function in patients with significant secondary tricuspid regurgitation (STR) remains challenging. In patients with severe aortic stenosis treated with transcatheter aortic valve implantation (TAVI), STR and RV enlargement have been associated with poor outcomes. In these patients, speckle tracking echocardiography (STE) may detect RV systolic dysfunction better than 3-dimensional (3D) RV ejection fraction (EF). The purpose of this study was to inves... Abstract
Cited 60 times since 2020 (12.8 per year) source: EuropePMC
Circulation. Genomic and precision medicine, Volume 13, Issue 5, 14 2 2020, Pages 541-547 Metabolic Age Based on the BBMRI-NL <sup>1</sup>H-NMR Metabolomics Repository as Biomarker of Age-related Disease. van den Akker EB, Trompet S, Barkey Wolf JJH, Beekman M, Suchiman HED, Deelen J, Asselbergs FW, Boersma E, Cats D, Elders PM, Geleijnse JM, Ikram MA, Kloppenburg M, Mei H, Meulenbelt I, Mooijaart SP, Nelissen RGHH, Netea MG, Penninx BWJH, Slofstra M, Stehouwer CDA, Swertz MA, Teunissen CE, Terwindt GM, 't Hart LM, van den Maagdenberg AMJM, van der Harst P, van der Horst ICC, van der Kallen CJH, van Greevenbroek MMJ, van Spil WE, Wijmenga C, Zhernakova A, Zwinderman AH, Sattar N, Jukema JW, van Duijn CM, Boomsma DI, Reinders MJT, Slagboom PE
Background: The blood metabolome incorporates cues from the environment and the host's genetic background, potentially offering a holistic view of an individual's health status. Methods: We have compiled a vast resource of proton nuclear magnetic resonance metabolomics and phenotypic data encompassing over 25 000 samples derived from 26 community and hospital-based cohorts. Results: Using this resource, we constructed a metabolomics-based age predictor (metaboAge) to calculate an indiv... Abstract
Cited 4 times since 2020 (0.9 per year) source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 60, Issue 5, 13 2 2020, Pages 655-662 Editor's Choice - A Systemic Evaluation of the Costs of Elective EVAR and Open Abdominal Aortic Aneurysm Repair Implies Cost Equivalence. Bulder RMA, Eefting D, Vriens PWHE, van Tongeren RB, Matsumura JS, van den Hout WB, Hamming JF, Lindeman JHN
Objective: The suggested high costs of endovascular aneurysm repair (EVAR) hamper the choice of insurance companies and financial regulators for EVAR as the primary option for elective abdominal aortic aneurysm (AAA) repair. However, arguments used in this debate are impeded by time related aspects such as effect modification and the introduction of confounding by indication, and by asymmetric evaluation of outcomes. Therefore, a re-evaluation minimising the impact of these interferences was con... Abstract