6128 results
Cited 9 times since 2019 (1.5 per year)
source: EuropePMC
Nature communications,
Volume 10, Issue 1, 1 1 2019, Pages 2068
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris
Christina M. Lill, who contributed to analysis of data, was inadvertently omitted from the author list in the originally published version of this article. This has now been corrected in both the PDF and HTML versions of the article.
Abstract
Cited 18 times since 2019 (3.1 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 8, Issue 9, 1 1 2019, Pages e010810
Metabolomics Profiling of Visceral Adipose Tissue: Results From MESA and the NEO Study.
Neeland IJ, Boone SC, Mook-Kanamori DO, Ayers C, Smit RAJ, Tzoulaki I, Karaman I, Boulange C, Vaidya D, Punjabi N, Allison M, Herrington DM, Jukema JW, Rosendaal FR, Lamb HJ, van Dijk KW, Greenland P, de Mutsert R
Background Identifying associations between serum metabolites and visceral adipose tissue ( VAT ) could provide novel biomarkers of VAT and insights into the pathogenesis of obesity-related diseases. We aimed to discover and replicate metabolites reflecting pathways related to VAT . Methods and Results Associations between fasting serum metabolites and VAT area (by computed tomography or magnetic resonance imaging) were assessed with cross-sectional linear regression of individual-level data fro...
Abstract
Cited 4 times since 2019 (0.7 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 55, Issue 5, 1 1 2019, Pages 859-866
Male-female differences in characteristics and early outcomes of patients undergoing tricuspid valve surgery: a national cohort study in the Netherlands.
Veen KM, Mokhles MM, Braun J, Versteegh MIM, Bogers AJJC, Takkenberg JJM
Objectives: This study aims to explore male-female differences in baseline and procedural characteristics, and outcomes of patients undergoing isolated or concomitant tricuspid valve (TV) surgery. Methods: All TV procedures registered between 2007 and 2016 in the database of the Netherlands Association for Cardio-Thoracic Surgery were analysed. Logistic regression analyses with interaction terms were used to determine whether sex was associated with hospital mortality. Results: Five thousand fiv...
Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 55, Issue 5, 1 1 2019, Pages 1019-1020
Reply to Böning.
Schneider AW, Klautz RJM, Hazekamp MG, Braun J
Abstract
Cited 2 times since 2019 (0.3 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 12, Issue 5, 1 1 2019, Pages e009086
Unraveling the Complex Processes of Adverse Cardiac Remodeling.
Kwong RY, Bax JJ
Abstract
Cited 9 times since 2019 (1.5 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 18, 1 1 2019, Pages 1440-1453
Should NICE guidelines be universally accepted for the evaluation of stable coronary disease? A debate.
Hecht HS, Shaw L, Chandrashekhar YS, Bax JJ, Narula J
The 2016 National Institute of Health and Care Excellence clinical guideline for the assessment and diagnosis of chest pain positions coronary computed tomography angiography as the first test for all stable chest pain patients without confirmed coronary artery disease and discards the previous emphasis on calculation of pre-test likelihood recommended in their 2012 edition of the guidelines. On the other hand, the American College of Cardiology Foundation/American Heart Association and the Euro...
Abstract
Cited 117 times since 2019 (20 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 73, Issue 17, 1 1 2019, Pages 2150-2162
Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis.
Zheng KH, Tsimikas S, Pawade T, Kroon J, Jenkins WSA, Doris MK, White AC, Timmers NKLM, Hjortnaes J, Rogers MA, Aikawa E, Arsenault BJ, Witztum JL, Newby DE, Koschinsky ML, Fayad ZA, Stroes ESG, Boekholdt SM, Dweck MR
Background: Lipoprotein(a) [Lp(a)], a major carrier of oxidized phospholipids (OxPL), is associated with an increased incidence of aortic stenosis (AS). However, it remains unclear whether elevated Lp(a) and OxPL drive disease progression and are therefore targets for therapeutic intervention. Objectives: This study investigated whether Lp(a) and OxPL on apolipoprotein B-100 (OxPL-apoB) levels are associated with disease activity, disease progression, and clinical events in AS patients, along wi...
Abstract
Cited 4 times since 2019 (0.7 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 20, Issue 5, 1 1 2019, Pages 591-599
Longitudinal quantitative assessment of coronary plaque progression related to body mass index using serial coronary computed tomography angiography.
Won KB, Lee SE, Lee BK, Park HB, Heo R, Rizvi A, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, Leipsic JA, Shin S, Choi JH, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Chang HJ
Aims: This study explored the coronary plaque volume change (PVC) according to the change of percent body mass index (BMI) and categorical BMI group using serial coronary computed tomography angiography (CCTA). Methods and results: A total of 1568 subjects who underwent serial CCTA with available BMI at baseline (CCTA1) and follow-up (CCTA2) were included. Median inter-scan period was 3.3 (interquartile range: 2.6-4.6) years. Quantitative assessment of coronary plaque was performed at both scans...
Abstract
Cited 19 times since 2019 (3.2 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 6, 26 4 2019, Pages 52
Anti-fibrotic Effects of Cardiac Progenitor Cells in a 3D-Model of Human Cardiac Fibrosis.
Bracco Gartner TCL, Deddens JC, Mol EA, Magin Ferrer M, van Laake LW, Bouten CVC, Khademhosseini A, Doevendans PA, Suyker WJL, Sluijter JPG, Hjortnaes J
Cardiac fibroblasts play a key role in chronic heart failure. The conversion from cardiac fibroblast to myofibroblast as a result of cardiac injury, will lead to excessive matrix deposition and a perpetuation of pro-fibrotic signaling. Cardiac cell therapy for chronic heart failure may be able to target fibroblast behavior in a paracrine fashion. However, no reliable human fibrotic tissue model exists to evaluate this potential effect of cardiac cell therapy. Using a gelatin methacryloyl hydroge...
Abstract
Cited 6 times since 2019 (1 per year)
source: EuropePMC
Circulation journal : official journal of the Japanese Circulation Society,
Volume 83, Issue 6, 18 3 2019, Pages 1293-1301
Clinical Impact of Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve on Japanese Population in the ADVANCE Registry.
Shiono Y, Matsuo H, Kawasaki T, Amano T, Kitabata H, Kubo T, Morino Y, Yoda S, Sakamoto T, Ito H, Shite J, Otake H, Tanaka N, Terashima M, Kadota K, Patel MR, Nieman K, Rogers C, Nørgaard BL, Bax JJ, Raff GL, Chinnaiyan KM, Berman DS, Fairbairn TA, Hurwitz Koweek LM, Leipsic J, Akasaka T
Background: Coronary computed tomography angiography (cCTA)-derived fractional flow reserve (FFRCT) is a promising diagnostic method for the evaluation of coronary artery disease (CAD). However, clinical data regarding FFRCTin Japan are scarce, so we assessed the clinical impact of using FFRCTin a Japanese population. Methods and results: The ADVANCE registry is an international prospective FFRCTregistry of patients suspected of CAD. Of 5,083 patients, 1,829 subjects enrolled from Japan were ana...
Abstract
Cited 4 times since 2019 (0.7 per year)
source: EuropePMC
Clinical endocrinology,
Volume 91, Issue 1, 12 2 2019, Pages 82-86
A prospective study on glucagon responses to oral glucose and mixed meal and 7-year change in fasting glucose.
Koopman ADM, Beulens JW, van der Heijden A, Elders P, Dekker JM, Alssema M, Rutters F
Introduction: The role of insufficient glucagon suppression after an oral load in the development of type 2 diabetes mellitus is unclear. The aim of this study was to examine the association between glucagon responses at baseline and fasting glucose levels 7 years later. Methods: Data of the Hoorn Meal Study were used, an observational cohort study among 121 persons without diabetes with a mean age of 61.1 ± 6.7 years and 50% being female. The glucagon response to an oral glucose tolerance test...
Abstract
Cited 6 times since 2019 (1 per year)
source: EuropePMC
Molecular genetics and genomics : MGG,
Volume 294, Issue 4, 9 2 2019, Pages 1001-1006
Insufficient evidence for a role of SERPINF1 in otosclerosis.
Valgaeren H, Sommen M, Beyens M, Vandeweyer G, Schrauwen I, Schepers A, Schatteman I, Topsakal V, Dhooge I, Kunst H, Zanetti D, Huber AM, Hoischen A, Fransen E, Van Camp G
Otosclerosis is a common form of hearing loss (HL) due to abnormal remodeling of the otic capsule. The genetic causes of otosclerosis remain largely unidentified. Only mutations in a single gene, SERPINF1, were previously published in patients with familial otosclerosis. To unravel the contribution of genetic variation in this gene to otosclerosis, this gene was re-sequenced in a large population of otosclerosis patients and controls. Resequencing of the 5' and 3' UTRs, coding regions,...
Abstract
Cited 15 times since 2019 (2.5 per year)
source: EuropePMC
Cells,
Volume 8, Issue 4, 9 2 2019, Pages E334
Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis.
Kritikou E, Depuydt MAC, de Vries MR, Mulder KE, Govaert AM, Smit MD, van Duijn J, Foks AC, Wezel A, Smeets HJ, Slütter B, Quax PHA, Kuiper J, Bot I
The presence of mast cells in human atherosclerotic plaques has been associated with adverse cardiovascular events. Mast cell activation, through the classical antigen sensitized-IgE binding to their characteristic Fcε-receptor, causes the release of their cytoplasmic granules. These granules are filled with neutral proteases such as tryptase, but also with histamine and pro-inflammatory mediators. Mast cells accumulate in high numbers within human atherosclerotic tissue, particularly in the sho...
Abstract
Cited 1 times since 2019 (0.2 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 57, Issue 6, 3 1 2019, Pages 766
Saccular Aneurysm of the Brachiocephalic Vein.
van der Vorst JR, Veger HTC
Abstract
Cited 9 times since 2019 (1.5 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 108, Issue 1, 2 1 2019, Pages 167-174
Multicenter Phase II Clinical Trial of Isolated Lung Perfusion in Patients With Lung Metastases.
Beckers PAJ, Versteegh MIM, Van Brakel TJ, Braun J, Van Putte B, Maat APWM, Vergauwen W, Rodrigus I, Den Hengst W, Lardon F, De Bruijn E, Guetens G, De Boeck G, Gielis JF, Lauwers P, Denissen L, Hendriks JMH, Van Schil PE
Background: Up to 66% of patients show local pulmonary disease progression after pulmonary metastasectomy. Regional treatment with isolated lung perfusion (ILuP) may improve local control with minimal systemic adverse effects. The aims of this study were to evaluate local and distant control after ILuP, determine the effect on overall survival compared with historical controls, and confirm the safety and feasibility of ILuP. Methods: A total of 107 patients with resectable pulmonary metastases o...
Abstract
Cited 1 times since 2019 (0.2 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 55, Issue 4, 1 1 2019, Pages 751-759
Beyond the clinical impact of aortic and pulmonary valve implantation: health-related quality of life, informal care and productivity†.
Huygens SA, van der Kley F, Bekkers JA, Bogers AJJC, Takkenberg JJM, Rutten-van Mölken MPMH
Objectives: Our aim was to provide estimates of patient-reported health-related quality of life (HRQoL), use of informal care and productivity in patients after surgical aortic and pulmonary valve replacement and transcatheter aortic valve implantation. Methods: Consecutive cohorts of 1239 adult patients who had surgical aortic valve replacement or surgical pulmonary valve replacement and 433 patients who had transcatheter aortic valve implantation at 2 Dutch heart centres were cross-sectionally...
Abstract
Cited 8 times since 2019 (1.3 per year)
source: EuropePMC
Rheumatology (Oxford, England),
Volume 58, Issue 4, 1 1 2019, Pages 730-732
Prognostic properties of anti-topoisomerase antibodies in patients identified by the ACR/EULAR 2013 systemic sclerosis criteria.
Boonstra M, Ninaber MK, Ajmone Marsan N, Huizinga TWJ, Scherer HU, de Vries-Bouwstra JK
Abstract
Cited 12 times since 2019 (2 per year)
source: EuropePMC
Journal of cellular and molecular medicine,
Volume 23, Issue 6, 1 1 2019, Pages 3888-3896
IRF3 and IRF7 mediate neovascularization via inflammatory cytokines.
Simons KH, de Vries MR, de Jong RCM, Peters HAB, Jukema JW, Quax PHA
Objective: To elucidate the role of interferon regulatory factor (IRF)3 and IRF7 in neovascularization. Methods: Unilateral hind limb ischaemia was induced in Irf3-/- , Irf7-/- and C57BL/6 mice by ligation of the left common femoral artery. Post-ischaemic blood flow recovery in the paw was measured with laser Doppler perfusion imaging. Soleus, adductor and gastrocnemius muscles were harvested to investigate angiogenesis and arteriogenesis and inflammation. Results: Post-ischaemic blood flow reco...
Abstract
Cited 14 times since 2019 (2.4 per year)
source: EuropePMC
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology,
Volume 41, 1 1 2019, Pages 29-37
The role of hemodynamics in bicuspid aortopathy: a histopathologic study.
Grewal N, Girdauskas E, DeRuiter M, Goumans MJ, Poelmann RE, Klautz RJM, Gittenberger-de Groot AC
Background: A bicuspid aortic valve (BAV) is the most common congenital cardiac malformation and is associated with ascending aortic dilation in 60%-80% of patients. In this study, we aimed to address the role of hemodynamic influences on the development of aortopathy in BAV patients. Patient and methods: BAV (n=36) and tricuspid aortic valve (TAV) patients (n=17) undergoing aortic valve replacement underwent preoperative flow magnetic resonance imaging (MRI) assessment to detect the area of max...
Abstract
Cited 20 times since 2019 (3.4 per year)
source: EuropePMC
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
Volume 34, Issue 4, 1 1 2019, Pages 650-659
Low thyroid function is not associated with an accelerated deterioration in renal function.
Meuwese CL, van Diepen M, Cappola AR, Sarnak MJ, Shlipak MG, Bauer DC, Fried LP, Iacoviello M, Vaes B, Degryse J, Khaw KT, Luben RN, Åsvold BO, Bjøro T, Vatten LJ, de Craen AJM, Trompet S, Iervasi G, Molinaro S, Ceresini G, Ferrucci L, Dullaart RPF, Bakker SJL, Jukema JW, Kearney PM, Stott DJ, Peeters RP, Franco OH, Völzke H, Walsh JP, Bremner A, Sgarbi JA, Maciel RMB, Imaizumi M, Ohishi W, Dekker FW, Rodondi N, Gussekloo J, den Elzen WPJ, Thyroid Studies Collaboration
Background: Chronic kidney disease (CKD) is frequently accompanied by thyroid hormone dysfunction. It is currently unclear whether these alterations are the cause or consequence of CKD. This study aimed at studying the effect of thyroid hormone alterations on renal function in cross-sectional and longitudinal analyses in individuals from all adult age groups. Methods: Individual participant data (IPD) from 16 independent cohorts having measured thyroid stimulating hormone, free thyroxine levels...
Abstract
