Research

Publications

Below you can find a list of our published research.

6128 results

Cited 13 times since 2010 (0.9 per year) source: EuropePMC

BMC geriatrics, Volume 10, 1 1 2010, Pages 17 Impact of valvular heart disease on activities of daily living of nonagenarians: the Leiden 85-plus study a population based study. van Bemmel T, Delgado V, Bax JJ, Gussekloo J, Blauw GJ, Westendorp RG, Holman ER

Background: Data on the prevalence of valvular heart disease in very old individuals are scarce and based mostly on in-hospital series. In addition, the potential detrimental effect of valvular heart disease on the activities of daily living is unknown. The present study evaluated the prevalence of significant valvular heart disease and the impact of valvular heart disease on the activities of daily living in community dwelling nonagenarians. Nested within the Leiden 85-plus study, a population... Abstract

Cited 20 times since 2010 (1.3 per year) source: EuropePMC

World journal of surgery, Volume 34, Issue 4, 1 1 2010, Pages 852-860 Factors predicting outcome of total thyroidectomy in young patients with multiple endocrine neoplasia type 2: a nationwide long-term follow-up study. Schreinemakers JM, Vriens MR, Valk GD, de Groot JW, Plukker JT, Bax K, Hamming JF, van der Luijt RB, Aronson DC, Borel Rinkes IH

BACKGROUND Multiple endocrine neoplasia type 2 (MEN 2) is caused by a RET mutation in chromosome 10. All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. METHODS In a nationwide case-control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), h... Abstract

Cited 1 times since 2010 (0.1 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 26, Issue 6, 1 1 2010, Pages 661-664 Positron emission tomography; viable tool in patients pre-CABG? van der Wall EE, Siebelink HM, Scholte AJ, Bax JJ

Abstract

Cited 5 times since 2010 (0.3 per year) source: EuropePMC

Journal of vascular surgery, Volume 52, Issue 1, 29 5 2010, Pages 152-158 The effect of injectable biocompatible elastomer (PDMS) on the strength of the proximal fixation of endovascular aneurysm repair grafts: an in vitro study. Bosman WM, van der Steenhoven TJ, Suárez DR, Valstar ER, de Vries AC, Brom HL, Jacobs MJ, Hamming JF

Purpose: One of the major concerns in the long-term success of endovascular aneurysm repair (EVAR) is stent graft migration, which can cause type I endoleak and even aneurysm rupture. Fixation depends on the mechanical forces between the graft and both the aortic neck and the blood flow. Therefore, there are anatomical restrictions for EVAR, such as short and angulated necks. To improve the fixation of EVAR grafts, elastomer (PDMS) can be injected in the aneurysm sac. The support given by the el... Abstract

Cited 14 times since 2010 (0.9 per year) source: EuropePMC

Journal of biomedicine & biotechnology, Volume 2010, 22 4 2010, Pages 702836 Novel approaches to treat experimental pulmonary arterial hypertension: a review. Umar S, Steendijk P, Ypey DL, Atsma DE, van der Wall EE, Schalij MJ, van der Laarse A

Background: Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by an increase in pulmonary artery pressure leading to right ventricular (RV) hypertrophy, RV failure, and ultimately death. Current treatments can improve symptoms and reduce severity of the hemodynamic disorder but gradual deterioration in their condition often necessitates a lung transplant. Methods and results: In experimental models of PAH, particularly the model of monocrotaline-induced pulmonary... Abstract

Cited 7 times since 2010 (0.5 per year) source: EuropePMC

Journal of vascular surgery, Volume 51, Issue 5, 20 3 2010, Pages 1230-1237 Aortic customize: a new alternative endovascular approach to aortic aneurysm repair using injectable biocompatible elastomer. An in vitro study. Bosman WM, van der Steenhoven TJ, Hinnen JW, Kaptein BL, de Vries AC, Brom HL, Jacobs MJ, Hamming JF

Purpose: Aortic Customize is a new concept for endovascular aortic aneurysm repair in which a non polymerized elastomer is injected to fill the aneurysm sac around a balloon catheter. The aim of this in vitro study was to investigate the extent of aneurysm wall stress reduction by the presence of a noncompliant elastomer cuff. Methods: A thin-walled latex aneurysm (inner radius sac 18 mm, inner radius neck 8 mm), equipped with 12 tantalum markers, was attached to an in vitro circulation model. F... Abstract

Cited 22 times since 2010 (1.5 per year) source: EuropePMC

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, Volume 19, Issue 9, 19 3 2010, Pages 1540-1544 Spinal decompensation in degenerative lumbar scoliosis. de Vries AA, Mullender MG, Pluymakers WJ, Castelein RM, van Royen BJ

Due to the aging population, degenerative scoliosis is a growing clinical problem. It is associated with back pain and radicular symptoms. The pathogenesis of degenerative scoliosis lies in degenerative changes of the spinal structures, such as the intervertebral disc, the facet joints and the vertebrae itself. Possibly muscle weakness also plays a role. However, it is not clear what exactly causes the decompensation to occur and what determines the direction of the curve. It is known that in th... Abstract

European heart journal, Volume 31, Issue 9, 16 3 2010, Pages 1038-1040 Genetics of ACS and recurrent MI/cardiac death: are we getting to the heart of the (atherosclerotic) matter? Monraats PS, Jukema JW

Abstract

Cited 123 times since 2010 (8.2 per year) source: EuropePMC

Vaccine, Volume 28, Issue 20, 11 2 2010, Pages 3571-3581 Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers. van Dissel JT, Arend SM, Prins C, Bang P, Tingskov PN, Lingnau K, Nouta J, Klein MR, Rosenkrands I, Ottenhoff TH, Kromann I, Doherty TM, Andersen P

Though widely used, the BCG vaccine has had little apparent effect on rates of adult pulmonary tuberculosis. Moreover, the risk of disseminated BCG disease in immunocompromised individuals means that improved TB vaccines ideally need to be able to efficiently prime mycobacterially-naïve individuals as well as boost individuals previously vaccinated with BCG. Protective immunity against Mycobacterium tuberculosis is thought to depend on the generation of a Th1-type cellular immune response charac... Abstract

Cited 5 times since 2010 (0.3 per year) source: EuropePMC

Environmental monitoring and assessment, Volume 173, Issue 1-4, 11 2 2010, Pages 1-16 Phytoplankton distribution during two contrasted summers in a Mediterranean harbour: combining automated submersible flow cytometry with conventional techniques. Thyssen M, Beker B, Ediger D, Yilmaz D, Garcia N, Denis M

Automated in situ flow cytometry, high-pressure liquid chromatography (HPLC), optical microscopy and fluorometry were combined to monitor phytoplankton over two summer periods (2005 and 2006). In 2006, temperature was higher and nutrients lower than in 2005, generating differences in the phytoplankton assemblages (i.e., abundance and structure). Pigment-size classes based on daily HPLC analysis provided evidence for higher proportions of picoplankton and nanoplankton with higher biomass in 2005... Abstract

Cited 22 times since 2010 (1.5 per year) source: EuropePMC

Clinical research in cardiology : official journal of the German Cardiac Society, Volume 99, Issue 6, 11 2 2010, Pages 345-357 Drug-eluting stents in acute myocardial infarction: updated meta-analysis of randomized trials. Dibra A, Tiroch K, Schulz S, Kelbaek H, Spaulding C, Laarman GJ, Valgimigli M, Di Lorenzo E, Kaiser C, Tierala I, Mehilli J, Campo G, Thuesen L, Vink MA, Schalij MJ, Violini R, Schömig A, Kastrati A

Background: Use of drug-eluting stents in patients with acute myocardial infarction (AMI) remains an "off label" indication due to concerns regarding their performance in this patient subset. Methods: We searched Medline, the Cochrane Central Register of Controlled Trials, and Internet-based sources of information on clinical trials in cardiology for randomized trials comparing drug-eluting stents with bare-metal stents in patients with AMI. Hazard ratios for the composite of death or... Abstract

Cited 42 times since 2010 (2.8 per year) source: EuropePMC

Circulation. Arrhythmia and electrophysiology, Volume 3, Issue 2, 9 2 2010, Pages 126-133 Arrhythmogenic right ventricular dysplasia/cardiomyopathy diagnostic task force criteria: impact of new task force criteria. Cox MG, van der Smagt JJ, Noorman M, Wiesfeld AC, Volders PG, van Langen IM, Atsma DE, Dooijes D, Houweling AC, Loh P, Jordaens L, Arens Y, Cramer MJ, Doevendans PA, van Tintelen JP, Wilde AA, Hauer RN

Background: Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) Diagnostic Task Force Criteria (TFC) proposed in 1994 are highly specific but lack sensitivity. A new international task force modified criteria to improve diagnostic yield. A comparison of diagnosis by 1994 TFC versus newly proposed criteria in 3 patient groups was conducted. Methods and results: In new TFC, scoring by major and minor criteria is maintained. Structural abnormalities are quantified and TFC highly spec... Abstract

Cited 268 times since 2010 (17.9 per year) source: EuropePMC

European heart journal, Volume 31, Issue 10, 5 1 2010, Pages 1220-1229 Mortality in adult congenital heart disease. Verheugt CL, Uiterwaal CS, van der Velde ET, Meijboom FJ, Pieper PG, van Dijk AP, Vliegen HW, Grobbee DE, Mulder BJ

Aims: Mortality in adults with congenital heart disease is known to be increased, yet its extent and the major mortality risks are unclear. Methods and results: The Dutch CONCOR national registry for adult congenital heart disease was linked to the national mortality registry. Cox's regression was used to assess mortality predictors. Of 6933 patients, 197 (2.8%) died during a follow-up of 24 865 patient-years. Compared with the general national population, there was excess mortality, partic... Abstract

Cited 11 times since 2010 (0.7 per year) source: EuropePMC

Arthritis research & therapy, Volume 12, Issue 2, 5 1 2010, Pages R38 TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies. van Nies JA, Marques RB, Trompet S, de Jong Z, Kurreeman FA, Toes RE, Jukema JW, Huizinga TW, van der Helm-van Mil AH

Introduction: Recently an association between a genetic variation in TRAF1/C5 and mortality from sepsis or cancer was found in rheumatoid arthritis (RA). The most prevalent cause of death, cardiovascular disease, may have been missed in that study, since patients were enrolled at an advanced disease stage. Therefore, we used an inception cohort of RA patients to investigate the association between TRAF1/C5 and cardiovascular mortality, and replicate the findings on all-cause mortality. As TRAF1/... Abstract

Cited 47 times since 2010 (3.1 per year) source: EuropePMC

Circulation. Arrhythmia and electrophysiology, Volume 3, Issue 2, 1 1 2010, Pages 148-154 Long-term outcome after ablative therapy of postoperative atrial tachyarrhythmia in patients with congenital heart disease and characteristics of atrial tachyarrhythmia recurrences. de Groot NM, Atary JZ, Blom NA, Schalij MJ

Background: Catheter ablation has evolved as a possible curative treatment modality for atrial tachyarrhythmia (AT) in patients with congenital heart defects (CHD). However, data on long-term outcome are scarce. We examined characteristics of recurrent AT after ablation of postoperative AT during long-term follow-up in CHD patients. Methods and results: CHD patients (n=53; 27 men; age, 38+/-15 years) referred for catheter ablation of AT were studied during a follow-up period of 5+/-3 years. Afte... Abstract

Cited 2 times since 2010 (0.1 per year) source: EuropePMC

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 12, Issue 3, 1 1 2010, Pages 311-312 Cardiac resynchronization therapy: relevance of right ventricular function evaluation. Delgado V, Bax JJ

Abstract

Cited 8 times since 2010 (0.5 per year) source: EuropePMC

Anesthesiology, Volume 112, Issue 3, 1 1 2010, Pages 557-566 Relation between preoperative and intraoperative new wall motion abnormalities in vascular surgery patients: a transesophageal echocardiographic study. Galal W, Hoeks SE, Flu WJ, van Kuijk JP, Goei D, Galema T, den Uil C, van Gestel YR, Bax JJ, Verhagen HJ, Poldermans D

Background: Coronary revascularization of the suspected culprit coronary lesion assessed by preoperative stress testing is not associated with improved outcome in vascular surgery patients. Methods: Fifty-four major vascular surgery patients underwent preoperative dobutamine echocardiography and intraoperative transesophageal echocardiography. The locations of left ventricular rest wall motion abnormalities and new wall motion abnormalities (NWMAs) were scored using a seven-wall model. During 30... Abstract

Cited 6 times since 2010 (0.4 per year) source: EuropePMC

Journal of vascular surgery, Volume 51, Issue 3, 1 1 2010, Pages 622-627 Patient and procedure-related risk factors for adverse events after infrainguinal bypass. Flu HC, Ploeg AJ, Marang-van de Mheen PJ, Veen EJ, Lange CP, Breslau PJ, Roukema JA, Hamming JF, Lardenoye JW

Background: Current medical practice urges individual health care facilities and medical professionals to obtain and provide detailed insight in quality of care with the possibility of comparing data between institutions. Adverse event (AE) analysis serves as a mainstay in quality assessment in vascular surgery, but the comparison of AE data between facilities can be complex. The aim of the present study was to assess independent risk factors for AE occurrence: patient, disease and operation cha... Abstract

Cited 26 times since 2010 (1.7 per year) source: EuropePMC

Current cardiology reports, Volume 12, Issue 2, 1 1 2010, Pages 185-191 The use of nuclear imaging for cardiac resynchronization therapy. Chen J, Boogers MJ, Bax JJ, Soman P, Garcia EV

Cardiac resynchronization therapy (CRT) has shown benefits in patients with end-stage heart failure, depressed left ventricular (LV) ejection fraction (< or = 35%), and prolonged QRS duration (> or = 120 ms). However, based on the conventional criteria, 20% to 40% of patients fail to respond to CRT. Studies have focused on important parameters for predicting CRT response, such as LV dyssynchrony, scar burden, LV lead position, and site of latest activation. Phase analysis allows nuclear ca... Abstract

Cited 6 times since 2010 (0.4 per year) source: EuropePMC

Circulation, Volume 121, Issue 12, 1 1 2010, Pages e252; author reply e253 Letter by Winter et al regarding article, "Children and adults with congenital heart disease lost to follow-up: who and when?". Winter MM, Mulder BJ, van der Velde ET

Abstract