8309 results
Cited 21 times since 2014 (2 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 101, Issue 2, 20 3 2014, Pages 94-100
Non-invasive imaging in atrial fibrillation: focus on prognosis and catheter ablation.
Bax JJ, Marsan NA, Delgado V
Imaging identifies patients with high-risk phenotype among the general population with atrial fibrillation, such as the presence of structural and valvular heart disease, which are both related to adverse outcome. Imaging is also potentially important for prediction of success of catheter ablation. Specifically, patients with larger left atrial size, reduced left atrial function and increased left atrial fibrosis content are more likely to experience atrial fibrillation recurrences after ablatio...
Abstract
Cited 11 times since 2014 (1.1 per year)
source: EuropePMC
Journal of magnetic resonance imaging : JMRI,
Volume 42, Issue 2, 19 3 2014, Pages 390-399
Automated left ventricle segmentation in late gadolinium-enhanced MRI for objective myocardial scar assessment.
Tao Q, Piers SR, Lamb HJ, van der Geest RJ
Purpose: To develop and validate an objective and reproducible left ventricle (LV) segmentation method for late gadolinium enhanced (LGE) magnetic resonance imaging (MRI), which can facilitate accurate myocardial scar assessment. Materials and methods: A cohort of 25 ischemic patients and 25 nonischemic patients were included. A four-step algorithm was proposed: first, the Cine-MRI and LGE-MRI volume were globally registered; second, the registered Cine-MRI contours were fitted to each LGE-MRI s...
Abstract
Cited 39 times since 2014 (3.8 per year)
source: EuropePMC
Proceedings of the National Academy of Sciences of the United States of America,
Volume 111, Issue 48, 17 3 2014, Pages 17170-17175
Global structural changes of an ion channel during its gating are followed by ion mobility mass spectrometry.
Konijnenberg A, Yilmaz D, Ingólfsson HI, Dimitrova A, Marrink SJ, Li Z, Vénien-Bryan C, Sobott F, Koçer A
Mechanosensitive ion channels are sensors probing membrane tension in all species; despite their importance and vital role in many cell functions, their gating mechanism remains to be elucidated. Here, we determined the conditions for releasing intact mechanosensitive channel of large conductance (MscL) proteins from their detergents in the gas phase using native ion mobility-mass spectrometry (IM-MS). By using IM-MS, we could detect the native mass of MscL from Escherichia coli, determine vario...
Abstract
Cited 26 times since 2014 (2.5 per year)
source: EuropePMC
The Journal of clinical investigation,
Volume 124, Issue 12, 17 3 2014, Pages 5159-5174
Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.
Ali ZA, de Jesus Perez V, Yuan K, Orcholski M, Pan S, Qi W, Chopra G, Adams C, Kojima Y, Leeper NJ, Qu X, Zaleta-Rivera K, Kato K, Yamada Y, Oguri M, Kuchinsky A, Hazen SL, Jukema JW, Ganesh SK, Nabel EG, Channon K, Leon MB, Charest A, Quertermous T, Ashley EA
Angioplasty and stenting is the primary treatment for flow-limiting atherosclerosis; however, this strategy is limited by pathological vascular remodeling. Using a systems approach, we identified a role for the network hub gene glutathione peroxidase-1 (GPX1) in pathological remodeling following human blood vessel stenting. Constitutive deletion of Gpx1 in atherosclerotic mice recapitulated this phenotype of increased vascular smooth muscle cell (VSMC) proliferation and plaque formation. In an i...
Abstract
Cited 136 times since 2014 (13.2 per year)
source: EuropePMC
The Journal of urology,
Volume 193, Issue 4, 15 3 2014, Pages 1163-1169
The prostate health index selectively identifies clinically significant prostate cancer.
Loeb S, Sanda MG, Broyles DL, Shin SS, Bangma CH, Wei JT, Partin AW, Klee GG, Slawin KM, Marks LS, van Schaik RH, Chan DW, Sokoll LJ, Cruz AB, Mizrahi IA, Catalona WJ
Purpose: The Prostate Health Index (phi) is a new test combining total, free and [-2]proPSA into a single score. It was recently approved by the FDA and is now commercially available in the U.S., Europe and Australia. We investigate whether phi improves specificity for detecting clinically significant prostate cancer and can help reduce prostate cancer over diagnosis. Materials and methods: From a multicenter prospective trial we identified 658 men age 50 years or older with prostate specific an...
Abstract
Cited 4 times since 2014 (0.4 per year)
source: EuropePMC
PloS one,
Volume 9, Issue 11, 12 2 2014, Pages e112129
Molecular epidemiology of seal parvovirus, 1988-2014.
Bodewes R, Hapsari R, Rubio García A, Sánchez Contreras GJ, van de Bildt MW, de Graaf M, Kuiken T, Osterhaus AD
A novel parvovirus was discovered recently in the brain of a harbor seal (Phoca vitulina) with chronic meningo-encephalitis. Phylogenetic analysis of this virus indicated that it belongs to the genus Erythroparvovirus, to which also human parvovirus B19 belongs. In the present study, the prevalence, genetic diversity and clinical relevance of seal parvovirus (SePV) infections was evaluated in both harbor and grey seals (Halichoerus grypus) that lived in Northwestern European coastal waters from...
Abstract
Cited 8 times since 2014 (0.8 per year)
source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions,
Volume 85, Issue 3, 12 2 2014, Pages 480-487
Position of Edwards SAPIEN transcatheter valve in the aortic root in relation with the coronary ostia: implications for percutaneous coronary interventions.
Katsanos S, Debonnaire P, van der Kley F, van Rosendael PJ, Joyce E, de Graaf MA, Schalij MJ, Scholte AJ, Bax JJ, Ajmone Marsan N, Delgado V
Objectives: To determine the implications of stable coverage of the coronary ostia by the Edwards SAPIEN valve frame in terms of myocardial ischemia and subsequent percutaneous coronary intervention (PCI), following transcatheter aortic valve implantation (TAVI). Background: Edwards SAPIEN frame is frequently deployed relatively higher than recommended and may overlap the coronary ostia. Methods: A total of 142 patients (age 81 ± 7 years, male 49%) treated with Edwards SAPIEN valve and with mult...
Abstract
Cited 13 times since 2014 (1.3 per year)
source: EuropePMC
Heart rhythm,
Volume 12, Issue 3, 7 1 2014, Pages 533-539
Epicardial leads in adult cardiac resynchronization therapy recipients: a study on lead performance, durability, and safety.
Buiten MS, van der Heijden AC, Klautz RJM, Schalij MJ, van Erven L
Background: Transvenous left ventricular (LV) lead placement for cardiac resynchronization therapy-defibrillator (CRT-D) delivery is unsuccessful in 8% to 10% of cases. These patients might benefit from an epicardial lead. However, data on long-term epicardial lead performance are scarce. Furthermore, extracting an epicardial lead requires a rethoracotomy. Objective: The purpose of this study was to determine data on almost a decade of experience with epicardial leads and investigate the safety...
Abstract
Cited 4 times since 2014 (0.4 per year)
source: EuropePMC
Hamostaseologie,
Volume 35, Issue 2, 7 1 2014, Pages 113-120
The role of mast cells in atherosclerosis.
Wezel A, Quax PH, Kuiper J, Bot I
Rupture of an atherosclerotic plaque is the major underlying cause of adverse cardiovascular events such as myocardial infarction or stroke. Therapeutic interventions should therefore be directed towards inhibiting growth of atherosclerotic lesions as well as towards prevention of lesion destabilization. Interestingly, the presence of mast cells has been demonstrated in both murine and human plaques, and multiple interventional murine studies have pointed out a direct role for mast cells in earl...
Abstract
Cited 14 times since 2014 (1.4 per year)
source: EuropePMC
Nutrition and cancer,
Volume 67, Issue 1, 5 1 2014, Pages 137-144
Mechanism of inhibition of CYP1A1 and glutathione S-transferase activities in fish liver by quercetin, resveratrol, naringenin, hesperidin, and rutin.
Arinç E, Yilmaz D, Bozcaarmutlu A
Quercetin, resveratrol, naringenin, hesperidin, and rutin are phenolic compounds/flavonoids that may have roles in the reduction of cancer susceptibility. In this study, in vitro modulatory effects of them were studied on liver CYP1A1 associated 7-ethoxyresorufin-O-deethylase (EROD) activity and glutathione S-transferase (GST) activity of leaping mullet (Liza saliens). All of the phenolic compounds/flavonoids used exerted an inhibitory effect on both EROD and GST activities of fish. Quercetin, r...
Abstract
The Journal of thoracic and cardiovascular surgery,
Volume 148, Issue 5, 4 1 2014, Pages 2440-2442
Reply to the editor.
Grewal N, Gittenberger-de Groot AC, DeRuiter MC
Abstract
Cited 11 times since 2014 (1.1 per year)
source: EuropePMC
Journal of sex & marital therapy,
Volume 41, Issue 6, 3 1 2014, Pages 680-690
Prevalence and Correlates of Sexual Dysfunction in Men and Women With Type 2 Diabetes.
Rutte A, van Splunter MM, van der Heijden AA, Welschen LM, Elders PJ, Dekker JM, Snoek FJ, Enzlin P, Nijpels G
This study aimed to assess the prevalence and correlates of sexual dysfunction in a sample of Dutch men and women with type 2 diabetes. Patients with type 2 diabetes who were between the ages of 40 and 75 years from 4 Dutch diabetes centers were asked to complete self-report questionnaires covering sociodemographic characteristics, medical characteristics, clinical depression (Center for Epidemiological Studies), and sexual dysfunction (in men: International Index of Erectile Function; in women:...
Abstract
Cited 3 times since 2014 (0.3 per year)
source: EuropePMC
JMIR research protocols,
Volume 3, Issue 4, 3 1 2014, Pages e52
Treatment of Infantile Hemangioma in Regional Hospitals With eHealth Support: Evaluation of Feasibility and Acceptance by Parents and Doctors.
de Graaf M, Totté JE, van Os-Medendorp H, van Renselaar W, Breugem CC, Pasmans SG
Background: Since beta blockers became the preferred treatment for infantile hemangiomas (IH), the number of patients eligible for treatment is increasing. Currently treatment of IH with beta blockers is mainly reserved for expert centers, where wait times are lengthening. This demonstrated the need for development of a more efficient and accessible way of providing care for children needing treatment for IH. An eHealth intervention, Hemangioma Treatment Plan (HTP), was developed to treat IH in...
Abstract
Cited 26 times since 2014 (2.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 16, Issue 3, 2 1 2014, Pages 290-299
Leaflet remodelling in functional mitral valve regurgitation: characteristics, determinants, and relation to regurgitation severity.
Debonnaire P, Al Amri I, Leong DP, Joyce E, Katsanos S, Kamperidis V, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Background: Recently, it has been hypothesized that mitral leaflet remodelling may play a role in the pathophysiology of functional mitral regurgitation (FMR). We investigated the characteristics, determinants, and relation of mitral leaflet remodelling to FMR severity. Methods and results: Three-dimensional transoesophageal echocardiographic data of the mitral valve (MV) were studied in 30 patients with FMR ≥ grade 3 (≥3), 24 patients with FMR < grade 3 (
Abstract
Cited 8 times since 2014 (0.8 per year)
source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology,
Volume 10, Issue 7, 1 1 2014, Pages 884-886
Tools & Techniques - Clinical: 3D transoesophageal echocardiography for selecting and guiding in percutaneous mitral valve repair using MitraClip.
Debonnaire P, Delgado V, Bax JJ, Marsan NA
Abstract
Cited 11 times since 2014 (1.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 22, Issue 11, 1 1 2014, Pages 484-490
Role of the ECG in initial acute coronary syndrome triage: primary PCI regardless presence of ST elevation or of non-ST elevation.
IJkema BB, Bonnier JJ, Schoors D, Schalij MJ, Swenne CA
The major initial triaging decision in acute coronary syndrome (ACS) is whether or not percutaneous coronary intervention (PCI) is the primary treatment. Current guidelines recommend primary PCI in ST-elevation ACS (STEACS) and initial antithrombotic therapy in non-ST-elevation ACS (NSTEACS). This review probes the question whether this decision can indeed be based on the ECG. Genesis of STE/NSTE ECGs depends on the coronary anatomy, collateral circulation and site of the culprit lesion. Other c...
Abstract
Cited 16 times since 2014 (1.5 per year)
source: EuropePMC
British journal of clinical pharmacology,
Volume 78, Issue 5, 1 1 2014, Pages 950-960
Evaluation of lecithinized human recombinant super oxide dismutase as cardioprotectant in anthracycline-treated breast cancer patients.
Broeyer FJ, Osanto S, Suzuki J, de Jongh F, van Slooten H, Tanis BC, Bruning T, Bax JJ, Ritsema van Eck HJ, de Kam ML, Cohen AF, Mituzhima Y, Burggraaf J
Aim: Anthracycline-induced cardiotoxicity is (partly) mediated by free radical overload. A randomized study was performed in breast cancer patients to investigate whether free radical scavenger super oxide dismutase (SOD) protects against anthracycline-induced cardiotoxicity as measured by changes in echo, electrocardiography and an array of biomarkers. Method and results: Eighty female, chemotherapy-naïve breast cancer patients (median age 49, range 24-67 years) scheduled for four or five cours...
Abstract
Cited 3 times since 2014 (0.3 per year)
source: EuropePMC
Chest,
Volume 146, Issue 5, 1 1 2014, Pages 1310-1318
Predicting mortality and morbidity after elective cardiac surgery using vasoactive and inflammatory biomarkers with and without the EuroSCORE model.
Schoe A, Schippers EF, Ebmeyer S, Struck J, Klautz RJM, de Jonge E, van Dissel JT
Background: In cardiac surgery, preoperative mortality risk assessment tools like the EuroSCORE help to guide physicians in optimizing perioperative care of patients. We investigated the value of preoperative levels of inflammatory (procalcitonin [PCT]) and vasoactive (C-terminal pro-arginine vasopressin [CT-proAVP], midregional pro-atrial natriuretic peptide [MR-proANP], midregional proadrenomedullin [MR-proADM], and C-terminal pro-endothelin-1 [CT-proET-1]) biomarkers for risk assessment of mo...
Abstract
Cited 43 times since 2014 (4.2 per year)
source: EuropePMC
Biology letters,
Volume 10, Issue 11, 1 1 2014, Pages 20140508
The ecology of primate material culture.
Koops K, Visalberghi E, van Schaik CP
Tool use in extant primates may inform our understanding of the conditions that favoured the expansion of hominin technology and material culture. The 'method of exclusion' has, arguably, confirmed the presence of culture in wild animal populations by excluding ecological and genetic explanations for geographical variation in behaviour. However, this method neglects ecological influences on culture, which, ironically, may be critical for understanding technology and thus material cultu...
Abstract
Cited 48 times since 2014 (4.6 per year)
source: EuropePMC
Inflammatory bowel diseases,
Volume 20, Issue 11, 1 1 2014, Pages 2013-2021
Carbohydrate intake in the etiology of Crohn's disease and ulcerative colitis.
Chan SS, Chan SS, Luben R, van Schaik F, Oldenburg B, Bueno-de-Mesquita HB, Hallmans G, Karling P, Lindgren S, Grip O, Key T, Crowe FL, Bergmann MM, Overvad K, Palli D, Masala G, Khaw KT, Racine A, Carbonnel F, Boutron-Ruault MC, Olsen A, Tjonneland A, Kaaks R, Tumino R, Trichopoulou A, Hart AR
Background: Diet may have a role in the etiology of inflammatory bowel disease. In previous studies, the associations between increased intakes of carbohydrates, sugar, starch, and inflammatory bowel disease are inconsistent. However, few prospective studies have investigated the associations between these macronutrients and incident Crohn's disease (CD) or ulcerative colitis (UC). Methods: A total of 401,326 men and women were recruited between 1991 and 1998. At recruitment, dietary intake...
Abstract
