Research

Publications

Below you can find a list of our published research.

9543 results

Cited 30 times since 2024 (23.5 per year) source: EuropePMC

The lancet. Gastroenterology & hepatology, Volume 9, Issue 10, 13 2 2024, Pages 924-934 Indocyanine green near-infrared fluorescence bowel perfusion assessment to prevent anastomotic leakage in minimally invasive colorectal surgery (AVOID): a multicentre, randomised, controlled, phase 3 trial. Faber RA, Meijer RPJ, Droogh DHM, Jongbloed JJ, Bijlstra OD, Boersma F, Braak JPBM, Meershoek-Klein Kranenbarg E, Putter H, Holman FA, Mieog JSD, Neijenhuis PA, van Staveren E, Bloemen JG, Burger JWA, Aukema TS, Brouwers MAM, Marinelli AWKS, Westerterp M, Doornebosch PG, van der Weijde A, Bosscha K, Handgraaf HJM, Consten ECJ, Sikkenk DJ, Burggraaf J, Keereweer S, van der Vorst JR, Hutteman M, Peeters KCMJ, Vahrmeijer AL, Hilling DE

Background: Anastomotic leakage is a severe postoperative complication in colorectal surgery and compromised bowel perfusion is considered a major contributing factor. Conventional methods to assess bowel perfusion have a low predictive value for anastomotic leakage. We therefore aimed to evaluate the efficacy of real-time assessment with near-infrared (NIR) fluorescence imaging with indocyanine green (ICG) in the prevention of anastomotic leakage. Methods: This multicentre, randomised, controll... Abstract

Cited 6 times since 2024 (4.7 per year) source: EuropePMC

Antimicrobial agents and chemotherapy, Volume 68, Issue 9, 13 2 2024, Pages e0065024 Bacteriophage therapy reduces Staphylococcus aureus in a porcine and human ex vivo burn wound infection model. Molendijk MM, Boekema BKHL, Lattwein KR, Vlig M, Bode LGM, Koopmans MPG, Verbon A, de Graaf M, van Wamel WJB

Burn wounds are a major burden, with high mortality rates due to infections. Staphylococcus aureus is a major causative agent of burn wound infections, which can be difficult to treat because of antibiotic resistance and biofilm formation. An alternative to antibiotics is the use of bacteriophages, viruses that infect and kill bacteria. We investigated the efficacy of bacteriophage therapy for burn wound infections, in both a porcine and a newly developed human ex vivo skin model. In both models... Abstract

Journal of thoracic disease, Volume 16, Issue 8, 13 2 2024, Pages 4914-4923 Deep learning to predict long-term mortality from plain chest X-ray in patients referred for suspected coronary artery disease. D'Ancona G, Savardi M, Massussi M, Van Der Valk V, Scherptong RWC, Signoroni A, Farina D, Murero M, Ince H, Benussi S, Curello S, Arslan F

Background: The hypothesis that a deep learning (DL) model can produce long-term prognostic information from chest X-ray (CXR) has already been confirmed within cancer screening programs. We summarize our experience with DL prediction of long-term mortality, from plain CXR, in patients referred for angina and coronary angiography. Methods: Data of patients referred to an Italian academic hospital were analyzed retrospectively. We designed a deep convolutional neural network (DCNN) that, from CXR... Abstract

Cited 1 times since 2024 (0.8 per year) source: EuropePMC

Holistic nursing practice, Volume 38, Issue 6, 9 2 2024, Pages 371-384 Effect of Acupressure on Menopausal Symptoms and Quality of Life in Postmenopausal Women: A Randomized Controlled Trial. Can AA, Yilmaz DV

This study was conducted as a randomized controlled experimental trial with the aim of determining the effect of acupressure on menopausal symptoms and quality of life in postmenopausal women, as well as the correlation between the two. This randomized controlled experimental study was conducted between May and November 2021 with women coming to a Menopause School in Turkey. A Descriptive Characteristics Form, the Menopause Rating Scale, and the World Health Organization Quality of Life Scale Sh... Abstract

Cited 1 times since 2024 (0.8 per year) source: EuropePMC

Journal of cardiovascular electrophysiology, Volume 35, Issue 10, 8 2 2024, Pages 1972-1980 Characterization of atrial arrhythmias following mitral valve repair: Incidence and risk factors. El Mathari S, Tomšič A, Kharbanda RK, Zappala P, Wijnmaalen AP, Klautz RJM, Silva MR, Palmen M

Objectives: This study aims to investigate the occurrence, type and correlation of early and late atrial arrhythmias following mitral valve repair in patients with no preoperative history of atrial arrhythmias. Methods: Patients undergoing mitral valve (MV) repair for degenerative disease were included. Early and late postoperative electrocardiograms were evaluated for the incidence and type of atrial arrhythmia (atrial fibrillation [AF] or atrial tachycardia [AT]). Results: The 192 patients wer... Abstract

Cited 8 times since 2024 (6.2 per year) source: EuropePMC

Current biology : CB, Volume 34, Issue 16, 7 1 2024, Pages 3735-3746.e5 Targeted memory reactivation to augment treatment in post-traumatic stress disorder. van der Heijden AC, van der Werf YD, van den Heuvel OA, Talamini LM, van Marle HJF

Post-traumatic stress disorder (PTSD) is a psychiatric disorder with traumatic memories at its core. Post-treatment sleep may offer a unique time window to increase therapeutic efficacy through consolidation of therapeutically modified traumatic memories. Targeted memory reactivation (TMR) enhances memory consolidation by presenting reminder cues (e.g., sounds associated with a memory) during sleep. Here, we applied TMR in PTSD patients to strengthen therapeutic memories during sleep after one t... Abstract

Frontiers in immunology, Volume 15, 5 1 2024, Pages 1466387 Corrigendum: Establishment and immune phenotyping of patient-derived glioblastoma models in humanized mice. Liu L, van Schaik TA, Chen KS, Rossignoli F, Borges P, Vrbanac V, Wakimoto H, Shah K

[This corrects the article DOI: 10.3389/fimmu.2023.1324618.]. Abstract

Cited 14 times since 2024 (10.8 per year) source: EuropePMC

Annals of surgery, Volume 280, Issue 5, 5 1 2024, Pages 763-771 Milestones in Surgical Complication Reporting: Clavien-Dindo Classification 20 Years and Comprehensive Complication Index 10 Years. Abbassi F, Pfister M, Lucas KL, Domenghino A, Puhan MA, Clavien PA, Outcome Reporting Group

Objective: To provide improved guidance for the consistent application of the Clavien-Dindo classification (CDC) and Comprehensive Complication Index (CCI ® ) in challenging clinical scenarios. Background: Standardized outcome reporting is key for the proper assessment of surgical procedures. A recent consensus conference recommended the CDC and the CCI ® for assessing postoperative morbidity. Several challenging scenarios for grading complications still require evidence-based guidance, and the... Abstract

Future oncology (London, England), Volume 20, Issue 27, 5 1 2024, Pages 2015-2022 Expression of integrin αvβ3 in medullary thyroid carcinoma. de Vries LH, Lodewijk L, Pijnappel EW, van Diest PJ, Schepers A, Bonenkamp HJ, van Engen-van Grunsven IA, Kruijff S, van Hemel BM, Links TP, Nieveen van Dijkum EJ, van Eeden S, van Leeuwaarde RS, Valk GD, de Keizer B, Borel Rinkes IH, Vriens MR

Aim: Tumor markers often remain elevated after intended curative resection of medullary thyroid carcinoma (MTC). The aim of this study was to determine the expression of αvβ3, a promising theranostics target, in MTC and its metastases.Materials & methods: Avβ3 expression was analyzed in 104 patients using a tissue microarray and correlated with clinicopathological variables and survival.Results: Cytoplasmic αvβ3 positivity was seen in 70 patients and was associated with lymph node metastases... Abstract

Journal of electrocardiology, Volume 86, 5 1 2024, Pages 153768 Rationale and design of the artificial intelligence scalable solution for acute myocardial infarction (ASSIST) study. Domingo-Gardeta T, Montero-Cabezas JM, Jurado-Román A, Sabaté M, Aboal J, Baranchuk A, Carrillo X, García-Zamora S, Dores H, van der Valk V, Scherptong RWC, Andrés-Cordón JF, Vidal P, Moreno-Martínez D, Toribio-Fernández R, Lillo-Castellano JM, Cruz R, De Guio F, Marina-Breysse M, Martínez-Sellés M

Background: Acute coronary syndrome (ACS), specifically ST-segment elevation myocardial infarction is a major cause of morbidity and mortality throughout Europe. Diagnosis in the acute setting is mainly based on clinical symptoms and physician's interpretation of an electrocardiogram (ECG), which may be subject to errors. ST-segment elevation is the leading criteria to activate urgent reperfusion therapy, but a clear ST-elevation pattern might not be present in patients with coronary occlus... Abstract

Cited 2 times since 2024 (1.5 per year) source: EuropePMC

Turkish journal of medical sciences, Volume 54, Issue 5, 5 1 2024, Pages 938-948 Relationship between microbiota awareness, nutrition literacy, and health literacy among adolescents. Ülker İ, Aydin MA, Yildiz M, Gökçay G, Elkoca A, Yildirim MS, Tanimowo A, Yilmaz DA

Background/aim: Microbiota awareness, nutritional literacy, and health literacy levels in adolescents have a significant impact on their health and well-being. This research was conducted to examine the relationship between microbiota awareness, nutrition literacy, and health literacy in adolescents. Material and methods: This research was structured with a descriptive-correlational design. The study population comprised adolescents aged 10-19 years, living in Türkiye (n = 739), between June 202... Abstract

Cited 10 times since 2024 (7.7 per year) source: EuropePMC

Physics of life reviews, Volume 50, 3 1 2024, Pages 211-225 Language follows a distinct mode of extra-genomic evolution. Bickel B, Giraud AL, Zuberbühler K, van Schaik CP

As one of the most specific, yet most diverse of human behaviors, language is shaped by both genomic and extra-genomic evolution. Sharing methods and models between these modes of evolution has significantly advanced our understanding of language and inspired generalized theories of its evolution. Progress is hampered, however, by the fact that the extra-genomic evolution of languages, i.e. linguistic evolution, maps only partially to other forms of evolution. Contrasting it with the biological... Abstract

Cited 1 times since 2024 (0.8 per year) source: EuropePMC

International journal of cardiology, Volume 415, 3 1 2024, Pages 132421 CIED-based remote monitoring in heart failure using the HeartLogic™ algorithm: Which patients benefit most? van der Lande ACMH, Feijen M, Egorova AD, Beles M, van Bockstal K, Phagu AAS, Schalij MJ, Heggermont WA, Beeres SLMA

Background & aims: Early identification of worsening HF enables timely adjustments to prevent hospitalization. Recent studies show the HeartLogic™ algorithm detects congestion and reduces HF events. However, it is unclear which patients benefit most. Therefore, this study aims to identify and characterize HF patients who benefit most from CIED-based remote monitoring with HeartLogic™. Methods: In this multicenter retrospective study, patients with a CIED and HeartLogic™ algorithm under struc... Abstract

Cited 1 times since 2024 (0.8 per year) source: EuropePMC

International journal of cardiology, Volume 414, 3 1 2024, Pages 132414 The prognostic value of changes in pulmonary vein flow patterns after surgical repair for primary mitral regurgitation. Yedidya I, Stassen J, Butcher S, van Wijngaarden AL, Wu Y, van der Bijl P, Marsan NA, Delgado V, Bax J

Background: The pulmonary vein (PV) flow pattern is influenced by the presence of mitral regurgitation (MR). After a successful reduction in MR severity, the pattern is expected to be changed. We aimed to evaluate the prognostic value of a change in the PV flow pattern in patients with primary MR undergoing mitral valve repair (MVR). Methods: The PV flow pattern was assessed with transthoracic echocardiography in 216 patients (age 65 [IQR 56-72] years, 70% male) with primary MR before and after... Abstract

Cited 3 times since 2024 (2.3 per year) source: EuropePMC

European heart journal. Cardiovascular Imaging, Volume 25, Issue 9, 1 1 2024, Pages 1296-1305 Structural and functional abnormalities of left-sided cardiac chambers in Barlow's disease without significant mitral regurgitation. Meucci MC, Mantegazza V, Wu HW, van Wijngaarden AL, Garlaschè A, Tamborini G, Pepi M, Bax JJ, Ajmone Marsan N

Aims: This study aims to explore the presence of left ventricular (LV) and left atrial (LA) morphological and functional abnormalities in patients with Barlow's disease (BD) without significant mitral regurgitation (MR) and to investigate whether these abnormalities may predict MR progression. Methods and results: Consecutive patients with BD were retrospectively identified from two tertiary centres; those with MR graded from trivial to mild-to-moderate were selected and matched with health... Abstract

Cited 6 times since 2024 (4.6 per year) source: EuropePMC

European heart journal, Volume 45, Issue 32, 1 1 2024, Pages 2954-2964 Pulmonary artery pressure monitoring in chronic heart failure: effects across clinically relevant subgroups in the MONITOR-HF trial. Clephas PRD, Zwartkruis VW, Malgie J, van Gent MWF, Brunner-La Rocca HP, Szymanski MK, van Halm VP, Handoko ML, Kok WEM, Asselbergs FW, van Kimmenade RRJ, Manintveld OC, van Mieghem NMDA, Beeres SLMA, Post MC, Borleffs CJW, Tukkie R, Mosterd A, Linssen GCM, Spee RF, Emans ME, Smilde TDJ, van Ramshorst J, Kirchhof CJHJ, Feenema-Aardema MW, da Fonseca CA, van den Heuvel M, Hazeleger R, van Eck M, van Heerebeek L, Boersma E, Rienstra M, de Boer RA, Brugts JJ

Background and aims: In patients with chronic heart failure (HF), the MONITOR-HF trial demonstrated the efficacy of pulmonary artery (PA)-guided HF therapy over standard of care in improving quality of life and reducing HF hospitalizations and mean PA pressure. This study aimed to evaluate the consistency of these benefits in relation to clinically relevant subgroups. Methods: The effect of PA-guided HF therapy was evaluated in the MONITOR-HF trial among predefined subgroups based on age, sex, a... Abstract

Aorta (Stamford, Conn.), Volume 12, Issue 4, 1 1 2024, Pages 86-93 The TRAIN Health Awareness Clinical Trial: Baseline Findings and Cardiovascular Risk Management in Aortic Dissection Patients. Bacour N, Grewal S, Tirpan AU, Theijse R, Erp OV, Klautz RJM, Sakalihasan N, Hultgren R, Grewal N

Acute Type A aortic dissection (ATAAD) is a life-threatening condition requiring timely surgical intervention. Despite successful surgery, postoperative outcomes are frequently suboptimal due to the high frequency of cardiovascular risk factors. This study examines baseline cardiovascular risk factors in a population of ATAAD patients in the Netherlands. Additionally, this study outlines the protocol for a randomized controlled trial, designed to improve postoperative management.Baseline data we... Abstract

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, Volume 35, Issue 8, 1 1 2024, Pages e14222 Reply to Sujoy Khan. van der Rijst LP, de Winter-de Groot KM, de Bruin-Weller MS, de Graaf M

Abstract

Cited 4 times since 2024 (3.1 per year) source: EuropePMC

European journal of preventive cardiology, Volume 31, Issue 10, 1 1 2024, Pages e75-e78 Comparison of change in lipoprotein(a) mass and molar concentrations by alirocumab and risk of subsequent cardiovascular events in ODYSSEY OUTCOMES. Szarek M, Reijnders E, Steg PG, Jukema JW, Schwertfeger M, Bhatt DL, Bittner VA, Diaz R, Fazio S, Garon G, Goodman SG, Harrington RA, White HD, Zeiher AM, Cobbaert C, Schwartz GG

Abstract

Cited 4 times since 2024 (3 per year) source: EuropePMC

Heart rhythm, Volume 22, Issue 2, 31 5 2024, Pages 536-543 ECTOPIC trial: The efficacy of flEcainide Compared To metOprolol in reducing Premature ventrIcular Contractions: A randomized open-label crossover study in pediatric patients. Bertels RA, Kammeraad JAE, van Geloven N, Filippini LH, van der Palen RLF, Tak RO, Frerich S, Vanagt W, Rehbock JJB, Knobbe I, Kuipers IM, de Riva M, Zeppenfeld K, Blom NA

Background: Frequent premature ventricular contractions (PVCs) in children are usually considered benign. Symptoms and left ventricular dysfunction are indications for treatment with antiarrhythmic drugs. Objective: This study aimed to evaluate the efficacy of flecainide vs metoprolol in reducing PVCs in children. Methods: A randomized open-label crossover trial was conducted of children with a PVC burden of >15% on Holter monitoring successively treated with metoprolol and flecainide, or vic... Abstract