9543 results
Cited 5 times since 2024 (3.1 per year)
source: EuropePMC
Lung cancer (Amsterdam, Netherlands),
Volume 191, 12 2 2024, Pages 107792
The optimal treatment for patients with stage I non-small cell lung cancer: minimally invasive lobectomy versus stereotactic ablative radiotherapy - a nationwide cohort study.
de Ruiter JC, van der Noort V, van Diessen JNA, Smit EF, Damhuis RAM, Hartemink KJ, ESLUNG group
Objectives: The aim of the Early-Stage LUNG cancer (ESLUNG) study was to compare outcomes after minimally invasive lobectomy (MIL) and stereotactic ablative radiotherapy (SABR) in patients with stage I non-small cell lung cancer (NSCLC). Materials and methods: In this retrospective cohort study, patients with clinical stage I NSCLC (according to TNM7), treated in 2014-2016 with MIL or SABR, were included. 5-year overall survival (OS) and recurrence-free survival (RFS) were calculated and compare...
Abstract
Cited 3 times since 2024 (1.9 per year)
source: EuropePMC
International journal of cardiology,
Volume 407, 10 2 2024, Pages 132015
Coronary artery calcium assessment on non-gated chest CT to optimize pre-operative cardiac screening in liver transplantation.
Groen RA, Barbero FL, Fischer SE, van Dijkman PRM, Bax JJ, Tushuizen ME, Jukema JW, Coenraad MJ, de Graaf MA
Background: Guidelines recommend standard pre-operative cardiac screening in all liver transplantation (LT) recipients, despite the relatively low prevalence of obstructive coronary artery disease. Most LT recipients often have non-gated computed tomography (CT) performed of the chest and abdomen. This study evaluated the ability of coronary artery calcification (CAC) assessment on consecutively available scans, to identify a selection of low-risk patients, in whom further cardiac imaging can be...
Abstract
Cited 1 times since 2024 (0.6 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 10, Issue 6, 10 2 2024, Pages 1050-1060
Incidence of Atrial Fibrillation After Radiofrequency Catheter Ablation for Atrial Tachycardia in Congenital Heart Disease.
Brouwer C, Hebe J, Nürnberg JH, Cosedis Nielsen J, Lukac P, de Riva M, Blom N, Zeppenfeld K
Background: Atrial tachycardia (AT) and atrial fibrillation (AF) coexist in 30% of congenital heart disease (CHD) patients. Successful atrial tachycardia catheter ablation (ATCA) might prevent AF. Data on new-onset AF after ATCA in CHD is scarce. Objectives: This study aimed to evaluate the incidence of new-onset AF after ATCA and to assess clinical characteristics associated with new-onset AF after ATCA in CHD. Methods: CHD patients referred for ATCA to 3 European centers were included. New occ...
Abstract
Cited 15 times since 2024 (9.3 per year)
source: EuropePMC
Journal of clinical lipidology,
Volume 18, Issue 4, 10 2 2024, Pages e548-e561
Alirocumab and cardiovascular outcomes according to sex and lipoprotein(a) after acute coronary syndrome: a report from the ODYSSEY OUTCOMES study.
Bittner VA, Schwartz GG, Bhatt DL, Chua T, De Silva HA, Diaz R, Goodman SG, Harrington RA, Jukema JW, McGinniss J, Pordy R, Garon G, Scemama M, White HD, Steg PG, Szarek M, ODYSSEY OUTCOMES Investigators
Background: The ODYSSEY OUTCOMES trial (NCT01663402) compared the effects of the proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab with placebo on major adverse cardiovascular events (MACE) in patients with recent acute coronary syndrome (ACS). Objective: We assessed efficacy and safety of alirocumab versus placebo according to sex and lipoprotein(a) level. Methods: This prespecified analysis compared the effects of alirocumab versus placebo on lipoproteins, MACE (coronary heart...
Abstract
Cited 1 times since 2024 (0.6 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 13, Issue 8, 9 2 2024, Pages e032033
Impact of a Chronic Total Coronary Occlusion on the Incidence of Appropriate Implantable Cardioverter-Defibrillator Shocks and Mortality: A Substudy of the Dutch Outcome in ICD Therapy (DO-IT)) Registry.
van Veelen A, Verstraelen TE, Somsen YBO, Elias J, van Dongen IM, Delnoy PPHM, Scholten MF, Boersma LVA, Maass AH, Strikwerda S, Firouzi M, Allaart CP, Vernooy K, Grauss RW, Tukkie R, Knaapen P, Zwinderman AH, Dijkgraaf MGW, Claessen BEPM, van Barreveld M, Wilde AAM, Henriques JPS, DO‐IT investigators *
Background: Chronic total coronary occlusions (CTO) substantially increase the risk for sudden cardiac death. Among patients with chronic ischemic heart disease at risk for sudden cardiac death, an implantable cardioverter defibrillator (ICD) is the favored therapy for primary prevention of sudden cardiac death. This study sought to investigate the impact of CTOs on the risk for appropriate ICD shocks and mortality within a nationwide prospective cohort. Methods and results: This is a subanalysi...
Abstract
Cited 16 times since 2024 (9.8 per year)
source: EuropePMC
The Lancet. Oncology,
Volume 25, Issue 5, 5 1 2024, Pages 603-613
MRI-guided optimisation of neoadjuvant chemotherapy duration in stage II-III HER2-positive breast cancer (TRAIN-3): a multicentre, single-arm, phase 2 study.
van der Voort A, Louis FM, van Ramshorst MS, Kessels R, Mandjes IA, Kemper I, Agterof MJ, van der Steeg WA, Heijns JB, van Bekkum ML, Siemerink EJ, Kuijer PM, Scholten A, Wesseling J, Vrancken Peeters MTFD, Mann RM, Sonke GS, Dutch Breast Cancer Research Group
Background: Patients with stage II-III HER2-positive breast cancer have good outcomes with the combination of neoadjuvant chemotherapy and HER2-targeted agents. Although increasing the number of chemotherapy cycles improves pathological complete response rates, early complete responses are common. We investigated whether the duration of chemotherapy could be tailored on the basis of radiological response. Methods: TRAIN-3 is a single-arm, phase 2 study in 43 hospitals in the Netherlands. Patient...
Abstract
Cited 1 times since 2024 (0.6 per year)
source: EuropePMC
International journal of cardiology,
Volume 407, 5 1 2024, Pages 132027
Decreased clinical performance in TGA-ASO patients after RVOT interventions; a multicenter European collaboration.
Engele LJ, González-Fernández V, Mulder BJM, Ruperti-Repilado FJ, Abia RL, van der Vlist K, Buendía F, Rueda J, Gabriel H, Schrutka L, Bouchardy J, Schwerzmann M, Possner M, Greutmann M, Gallego P, Ladouceur M, Jongbloed MRM, Tobler D, Dos L, Bouma BJ
Background: In patients with transposition of the great arteries and an arterial switch operation (TGA-ASO) right ventricular outflow tract (RVOT) obstruction is a common complication requiring one or more RVOT interventions. Objectives: We aimed to assess cardiopulmonary exercise capacity and right ventricular function in patients stratified for type of RVOT intervention. Methods: TGA-ASO patients (≥16 years) were stratified by type of RVOT intervention. The following outcome parameters were in...
Abstract
Cited 1 times since 2024 (0.6 per year)
source: EuropePMC
Journal of clinical medicine,
Volume 13, Issue 7, 5 1 2024, Pages 2118
Comparative Analysis of Therapeutic Strategies in Post-Cardiotomy Cardiogenic Shock: Insight into a High-Volume Cardiac Surgery Center.
Baldan BU, Hegeman RRMJJ, Bos NMJP, Smeenk HG, Klautz RJM, Klein P
Background: Post-cardiotomy cardiogenic shock (PCCS), which is defined as severe low cardiac output syndrome after cardiac surgery, has a mortality rate of up to 90%. No study has yet been performed to compare patients with PCCS treated by conservative means to patients receiving additional mechanical circulatory support with veno-arterial extracorporeal membrane oxygenation (ECMO). Methods: A single-center retrospective analysis from January 2018 to June 2022 was performed. Results: Out of 7028...
Abstract
Cited 1 times since 2024 (0.6 per year)
source: EuropePMC
Journal of cardiothoracic surgery,
Volume 19, Issue 1, 4 1 2024, Pages 174
Continuous or interrupted pledgeted suture technique in stented bioprosthetic aortic valve replacement: a comparison of in-hospital outcomes.
Arabkhani B, Gonthier S, Lorenz V, Deschamps S, Jahanyar J, Boute M, Vancraeynest D, Mastrobuoni S, Khoury GE, de Kerchove L
Background: There is ambiguity in the literature regarding the continuous suture technique (CST) for aortic valve replacement (AVR). At our center, there has been a gradual shift towards CST over the interrupted pledgeted technique (IPT). This study aims at comparing outcomes for both techniques. Methods: We performed a retrospective analysis of a single-center study of patients undergoing AVR between January 2011 and July 2020. Patients were divided into two groups: Continuous suture technique...
Abstract
Cited 2 times since 2024 (1.2 per year)
source: EuropePMC
Frontiers in molecular biosciences,
Volume 11, 3 1 2024, Pages 1288677
TGF-β mRNA levels in circulating extracellular vesicles are associated with response to anti-PD1 treatment in metastatic melanoma.
Crucitta S, Cucchiara F, Marconcini R, Bulleri A, Manacorda S, Capuano A, Cioni D, Nuzzo A, de Jonge E, Mathjissen RHJ, Neri E, van Schaik RHN, Fogli S, Danesi R, Del Re M
Introduction: Immune checkpoint inhibitors (ICIs) represent the standard therapy for metastatic melanoma. However, a few patients do not respond to ICIs and reliable predictive biomarkers are needed. Methods: This pilot study investigates the association between mRNA levels of programmed cell death-1 (PD-1) ligand 1 (PD-L1), interferon-gamma (IFN-γ), and transforming growth factor-β (TGF-β) in circulating extracellular vesicles (EVs) and survival in 30 patients with metastatic melanoma treated w...
Abstract
Cited 8 times since 2024 (4.9 per year)
source: EuropePMC
European journal of human genetics : EJHG,
Volume 32, Issue 8, 3 1 2024, Pages 903-911
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction of CYP2C9, HLA-A and HLA-B with anti-epileptic drugs.
Manson LEN, Nijenhuis M, Soree B, de Boer-Veger NJ, Buunk AM, Houwink EJF, Risselada A, Rongen GAPJM, van Schaik RHN, Swen JJ, Touw DJ, van Westrhenen R, Deneer VHM, Guchelaar HJ
By developing evidence-based pharmacogenetics guidelines to optimize pharmacotherapy, the Dutch Pharmacogenetics Working Group (DPWG) aims to advance the implementation of pharmacogenetics (PGx). This guideline outlines the gene-drug interaction of CYP2C9 and HLA-B with phenytoin, HLA-A and HLA-B with carbamazepine and HLA-B with oxcarbazepine and lamotrigine. A systematic review was performed and pharmacotherapeutic recommendations were developed. For CYP2C9 intermediate and poor metabolisers,...
Abstract
The lancet. Gastroenterology & hepatology,
Volume 9, Issue 4, 1 1 2024, Pages 293-294
Gluten and non-coeliac gluten sensitivity: the nocebo effect and future avenues - Authors' reply.
de Graaf MCG, Keszthelyi D, Brouns FJPH, Dye L, Jonkers DMAE, all authors
Abstract
Cited 2 times since 2024 (1.2 per year)
source: EuropePMC
European journal of clinical investigation,
Volume 54, Issue 8, 1 1 2024, Pages e14200
Prognostic significance of echocardiographic deformation imaging in adult congenital heart disease.
van Rosendael PJ, Taha K, Guglielmo M, Teske AJ, van der Harst P, Sieswerda G, Cramer MJ, van der Zwaan HB
Background: Due to medical and surgical advancements, the population of adult patients with congenital heart disease (ACHD) is growing. Despite successful therapy, ACHD patients face structural sequalae, placing them at increased risk for heart failure and arrhythmias. Left and right ventricular function are important predictors for adverse clinical outcomes. In acquired heart disease it has been shown that echocardiographic deformation imaging is of superior prognostic value as compared to conv...
Abstract
Cited 4 times since 2024 (2.4 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 25, Issue 5, 1 1 2024, Pages 657-667
Prognostic value of a novel artificial intelligence-based coronary computed tomography angiography-derived ischaemia algorithm for patients with suspected coronary artery disease.
Bär S, Nabeta T, Maaniitty T, Saraste A, Bax JJ, Earls JP, Min JK, Knuuti J
Aims: Coronary computed tomography angiography (CTA) imaging is used to diagnose patients with suspected coronary artery disease (CAD). A novel artificial intelligence-guided quantitative computed tomography ischaemia algorithm (AI-QCTischaemia) aims to identify myocardial ischaemia directly from CTA images and may be helpful to improve risk stratification. The aims were to investigate (i) the prognostic value of AI-QCTischaemia amongst symptomatic patients with suspected CAD entering diagnostic...
Abstract
Cited 2 times since 2024 (1.2 per year)
source: EuropePMC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology,
Volume 38, Issue 7, 1 1 2024, Pages e23579
Effects of repeated weight cycling on non-alcoholic steatohepatitis in diet-induced obese mice.
Inia JA, de Jong JCBC, Keijzer N, Menke AL, Princen HMG, Jukema JW, van den Hoek AM
Lifestyle interventions remain the treatment of choice for patients with obesity and metabolic complications, yet are difficult to maintain and often lead to cycles of weight loss and regain (weight cycling). Literature on weight cycling remains controversial and we therefore investigated the association between weight cycling and metabolic complications using preexistent obese mice. Ldlr-/-.Leiden mice received a high-fat diet (HFD) for 20 weeks to induce obesity. Subsequently, weight-cycled mi...
Abstract
Cited 20 times since 2024 (12.2 per year)
source: EuropePMC
European journal of heart failure,
Volume 26, Issue 4, 1 1 2024, Pages 1078-1089
Interatrial shunt therapy in advanced heart failure: Outcomes from the open-label cohort of the RELIEVE-HF trial.
Rodés-Cabau J, Lindenfeld J, Abraham WT, Zile MR, Kar S, Bayés-Genís A, Eigler N, Holcomb R, Núñez J, Lee E, Perl ML, Moravsky G, Pfeiffer M, Boehmer J, Gorcsan J, Bax JJ, Anker S, Stone GW
Aims: Heart failure (HF) outcomes remain poor despite optimal guideline-directed medical therapy (GDMT). We assessed safety, effectiveness, and transthoracic echocardiographic (TTE) outcomes during the 12 months after Ventura shunt implantation in the RELIEVE-HF open-label roll-in cohort. Methods and results: Eligibility required symptomatic HF despite optimal GDMT with ≥1 HF hospitalization in the prior year or elevated natriuretic peptides. The safety endpoint was device-related major adverse...
Abstract
Cited 3 times since 2024 (1.8 per year)
source: EuropePMC
JAMA network open,
Volume 7, Issue 4, 1 1 2024, Pages e246556
Nationwide Association of Surgical Performance of Minimally Invasive Esophagectomy With Patient Outcomes.
Ketel MHM, Klarenbeek BR, Abma I, Belgers EHJ, Coene PLO, Dekker JWT, van Duijvendijk P, Emous M, Gisbertz SS, Haveman JW, Heisterkamp J, Nieuwenhuijzen GAP, Ruurda JP, van Sandick JW, van der Sluis PC, van Det MJ, van Esser S, Law S, de Steur WO, Sosef MN, Wijnhoven B, Hannink G, Rosman C, van Workum F, MIE-CAT Netherlands Collaborative Group
Importance: Suboptimal surgical performance is hypothesized to be associated with less favorable patient outcomes in minimally invasive esophagectomy (MIE). Establishing this association may lead to programs that promote better surgical performance of MIE and improve patient outcomes. Objective: To investigate associations between surgical performance and postoperative outcomes after MIE. Design, setting, and participants: In this nationwide cohort study of 15 Dutch hospitals that perform more t...
Abstract
IEEE transactions on biomedical circuits and systems,
Volume 18, Issue 2, 1 1 2024, Pages 423-437
Tau-Cell-Based Analog Silicon Retina With Spatio- Temporal Filtering and Contrast Gain Control.
Philip P, Jainwal K, van Schaik A, Thakur CS
Developing precise artificial retinas is crucial because they hold the potential to restore vision, improve visual prosthetics, and enhance computer vision systems. Emulating the luminance and contrast adaption features of the retina is essential to improve visual perception and efficiency to provide an environment realistic representation to the user. In this article, we introduce an artificial retina model that leverages its potent adaptation to luminance and contrast to enhance vision sensing...
Abstract
Cited 5 times since 2024 (3 per year)
source: EuropePMC
Radiology. Cardiothoracic imaging,
Volume 6, Issue 2, 1 1 2024, Pages e220197
Impact of Smoking on Coronary Volume-to-Myocardial Mass Ratio: An ADVANCE Registry Substudy.
Holmes KR, Gulsin GS, Fairbairn TA, Hurwitz-Koweek L, Matsuo H, Nørgaard BL, Jensen JM, Sand NR, Nieman K, Bax JJ, Pontone G, Chinnaiyan KM, Rabbat MG, Amano T, Kawasaki T, Akasaka T, Kitabata H, Rogers C, Patel MR, Payne GW, Leipsic JA, Sellers SL
Purpose To examine the relationship between smoking status and coronary volume-to-myocardial mass ratio (V/M) among individuals with coronary artery disease (CAD) undergoing CT fractional flow reserve (CT-FFR) analysis. Materials and Methods In this secondary analysis, participants from the ADVANCE registry evaluated for suspected CAD from July 15, 2015, to October 20, 2017, who were found to have coronary stenosis of 30% or greater at coronary CT angiography (CCTA) were included if they had kno...
Abstract
Cited 3 times since 2024 (1.8 per year)
source: EuropePMC
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases,
Volume 30, Issue 7, 28 4 2024, Pages 930-936
Intradermal delivery of the third dose of the mRNA-1273 SARS-CoV-2 vaccine: safety and immunogenicity of a fractional booster dose.
Roozen GVT, Prins MLM, Prins C, Janse JJ, de Gruyter HLM, Pothast CR, Huisman W, Koopman JPR, Lamers OAC, Kuijer M, Myeni SK, van Binnendijk RS, Hartog GD, Heemskerk MHM, Jochems SP, Feltkamp MCW, Kikkert M, Rosendaal FR, Roestenberg M, Visser LG, Roukens AHE
Objectives: The aim of this study was to assess the safety and immunogenicity of a dose-sparing fractional intradermal (ID) booster strategy with the mRNA-1273 COVID-19 vaccine. Methods: COVID-19 naive adults aged 18-30 years were recruited from a previous study on primary vaccination regimens that compared 20 μg ID vaccinations with 100 μg intramuscular (IM) vaccinations with mRNA-1273 as the primary vaccination series. Participants previously immunized with ID regimens were randomly assigned (...
Abstract
