8684 results
Cited 21 times since 2020 (4.7 per year)
source: EuropePMC
Antimicrobial agents and chemotherapy,
Volume 65, Issue 1, 16 3 2020, Pages e01958-20
Evolution of Colistin Resistance in the Klebsiella pneumoniae Complex Follows Multiple Evolutionary Trajectories with Variable Effects on Fitness and Virulence Characteristics.
Janssen AB, Doorduijn DJ, Mills G, Rogers MRC, Bonten MJM, Rooijakkers SHM, Willems RJL, Bengoechea JA, van Schaik W
The increasing prevalence of multidrug-resistant Klebsiella pneumoniae has led to a resurgence in the use of colistin as a last-resort drug. Colistin is a cationic antibiotic that selectively acts on Gram-negative bacteria through electrostatic interactions with anionic phosphate groups of the lipid A moiety of lipopolysaccharides (LPSs). Colistin resistance in K. pneumoniae is mediated through loss of these phosphate groups, their modification by cationic groups, and by the hydroxylation of acy...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 29, Issue 1, 15 3 2020, Pages 1-3
Percutaneous coronary intervention for chronic total coronary occlusion: Do. Or do not. There is no try.
Knaapen P, Henriques JP, Nap A, Arslan F
Abstract
Cited 7 times since 2020 (1.6 per year)
source: EuropePMC
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases,
Volume 103, 14 2 2020, Pages 300-304
A high-throughput drug screening strategy against coronaviruses.
Liu J, Li K, Cheng L, Shao J, Yang S, Zhang W, Zhou G, de Vries AAF, Yu Z
The emergence and re-emergence of coronaviruses (CoV) continually cause circulating epidemics and pandemics worldwide, such as the on-going outbreak of the novel coronavirus SARS-CoV-2. The resultant disease, coronavirus disease 2019 (COVID-19), has rapidly developed into a worldwide pandemic, leading to severe health and economic burdens. Although the recently announced vaccines against COVID-19 has rekindled hope, there is still a major challenge to urgently meet the global need for rapid trea...
Abstract
EJVES vascular forum,
Volume 50, 13 2 2020, Pages 27
Mirror, Mirror on the Wall'?
van Schaik J, van Wissen RC
Abstract
Cited 6 times since 2020 (1.3 per year)
source: Scopus
International journal of medical informatics,
Volume 147, 13 2 2020, Pages 104364
A multi-stakeholder approach to eHealth development: Promoting sustained healthy living among cardiovascular patients.
Breeman LD, Keesman M, Atsma DE, Chavannes NH, Janssen V, van Gemert-Pijnen L, Kemps H, Kraaij W, Rauwers F, Reijnders T, Scholte Op Reimer W, Wentzel J, Kraaijenhagen RA, Evers AWM, BENEFIT consortium
Background: Healthy living is key in the prevention and rehabilitation of cardiovascular disease (CVD). Yet, supporting and maintaining a healthy lifestyle is exceptionally difficult and people differ in their needs regarding optimal support for healthy lifestyle interventions. Objective: The goals of this study were threefold: to uncover stakeholders' needs and preferences, to translate these to core values, and develop eHealth technology based on these core values. Our primary research qu...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Clinical neurophysiology practice,
Volume 6, 11 2 2020, Pages 16-21
Measuring CMAPs in addition to MEPs can distinguish peripheral ischemia from spinal cord ischemia during endovascular aortic repair.
Kerkhof FI, van Schaik J, Massaad RA, van Rijswijk CSP, Tannemaat MR
Objective: Spinal cord injury is a devastating complication after endovascular thoracic and thoracoabdominal aneurysm repair (EVAR). Motor evoked potentials (MEPs) can be monitored to detect spinal cord injury, but may also be affected by peripheral ischemia caused by femoral artery sheaths. We aimed to determine the incidence of peripheral ischemia during EVAR, and whether central and peripheral ischemia can be distinguished using compound muscle action potentials (CMAPs). Methods: We retrospec...
Abstract
Cited 4 times since 2020 (0.9 per year)
source: EuropePMC
Journal of dairy science,
Volume 104, Issue 2, 11 2 2020, Pages 2074-2086
The effect of bovine viral diarrhea virus introduction on milk production of Dutch dairy herds.
Yue X, Steeneveld W, van der Voort M, van Schaik G, Vernooij JCM, van Duijn L, Veldhuis AMB, Hogeveen H
Dairy cows are negatively affected by the introduction of bovine viral diarrhea virus (BVDV), and consequently, produce less milk. Existing literature on potential milk production losses is based on relatively outdated data and hardly evaluates milk production loss in relation to a new BVDV infection in a surveillance system. This study determined the annual and quarterly loss in milk production of BVDV introduction in 3,126 dairy herds participating in the Dutch BVDV-free program between 2007 a...
Abstract
Trauma case reports,
Volume 31, 11 2 2020, Pages 100379
A 'Final Destination injury': Penetrating trauma of the neck and a pneumomediastinum by a metal part shot from a lawnmower.
Quax MLJ, Eefting D, Jansen JC, Blok JJ
Introduction: Outside of war regions, penetrating neck injury is rare. Penetrating neck injury due to a lawnmower has never been described, despite the annual 74.000 injuries caused by lawnmowers in the United States. In this report, the case of a 65-year old women, admitted after a penetrating neck injury due to a metal piece shot from a lawnmower, is described. Report: A 65-year old women, with no relevant medical history, presented at the Emergency Department after she was hit in the neck by...
Abstract
Cited 83 times since 2020 (18.5 per year)
source: EuropePMC
Critical care (London, England),
Volume 24, Issue 1, 10 2 2020, Pages 688
Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study.
Kooistra EJ, Waalders NJB, Grondman I, Janssen NAF, de Nooijer AH, Netea MG, van de Veerdonk FL, Ewalds E, van der Hoeven JG, Kox M, Pickkers P, RCI-COVID-19 Study Group
Background: A subset of critically ill COVID-19 patients develop a hyperinflammatory state. Anakinra, a recombinant interleukin-1 receptor antagonist, is known to be effective in several hyperinflammatory diseases. We investigated the effects of anakinra on inflammatory parameters and clinical outcomes in critically ill, mechanically ventilated COVID-19 patients with clinical features of hyperinflammation. Methods: In this prospective cohort study, 21 critically ill COVID-19 patients treated wit...
Abstract
Cited 65 times since 2020 (14.5 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 14, Issue 1, 9 2 2020, Pages e008509
Sudden Cardiac Death Prediction in Arrhythmogenic Right Ventricular Cardiomyopathy: A Multinational Collaboration.
Cadrin-Tourigny J, Bosman LP, Wang W, Tadros R, Bhonsale A, Bourfiss M, Lie ØH, Saguner AM, Svensson A, Andorin A, Tichnell C, Murray B, Zeppenfeld K, van den Berg MP, Asselbergs FW, Wilde AAM, Krahn AD, Talajic M, Rivard L, Chelko S, Zimmerman SL, Kamel IR, Crosson JE, Judge DP, Yap SC, Van der Heijden JF, Tandri H, Jongbloed JDH, van Tintelen JP, Platonov PG, Duru F, Haugaa KH, Khairy P, Hauer RNW, Calkins H, Te Riele ASJM, James CA
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with ventricular arrhythmias (VA) and sudden cardiac death (SCD). A model was recently developed to predict incident sustained VA in patients with ARVC. However, since this outcome may overestimate the risk for SCD, we aimed to specifically predict life-threatening VA (LTVA) as a closer surrogate for SCD. Methods: We assembled a retrospective cohort of definite ARVC cases from 15 centers in North America and Europe....
Abstract
Cited 116 times since 2020 (25.8 per year)
source: EuropePMC
Nature communications,
Volume 11, Issue 1, 8 2 2020, Pages 6285
Cerebral small vessel disease genomics and its implications across the lifespan.
Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Akker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL, Beaudet G, Petit L, Tsuchida A, Zago L, Schilling S, Sigurdsson S, Gottesman RF, Lewis CE, Aggarwal NT, Lopez OL, Smith JA, Valdés Hernández MC, van der Grond J, Wright MJ, Knol MJ, Dörr M, Thomson RJ, Bordes C, Le Grand Q, Duperron MG, Smith AV, Knopman DS, Schreiner PJ, Evans DA, Rotter JI, Beiser AS, Maniega SM, Beekman M, Trollor J, Stott DJ, Vernooij MW, Wittfeld K, Niessen WJ, Soumaré A, Boerwinkle E, Sidney S, Turner ST, Davies G, Thalamuthu A, Völker U, van Buchem MA, Bryan RN, Dupuis J, Bastin ME, Ames D, Teumer A, Amouyel P, Kwok JB, Bülow R, Deary IJ, Schofield PR, Brodaty H, Jiang J, Tabara Y, Setoh K, Miyamoto S, Yoshida K, Nagata M, Kamatani Y, Matsuda F, Psaty BM, Bennett DA, De Jager PL, Mosley TH, Sachdev PS, Schmidt R, Warren HR, Evangelou E
White matter hyperintensities (WMH) are the most common brain-imaging feature of cerebral small vessel disease (SVD), hypertension being the main known risk factor. Here, we identify 27 genome-wide loci for WMH-volume in a cohort of 50,970 older individuals, accounting for modification/confounding by hypertension. Aggregated WMH risk variants were associated with altered white matter integrity (p = 2.5×10-7) in brain images from 1,738 young healthy adults, providing insight into the lifetime imp...
Abstract
Cited 14 times since 2020 (3.1 per year)
source: EuropePMC
Cancer treatment and research communications,
Volume 25, 8 2 2020, Pages 100266
Utilization of systemic treatment for metastatic bladder cancer in everyday practice: Results of a nation-wide population-based cohort study.
Richters A, Mehra N, Meijer RP, Boormans JL, van der Heijden AG, Smilde TJ, van der Heijden MS, Kiemeney LA, Aben KK
Background: With the introduction of new therapeutic options, the landscape of metastatic bladder cancer (mBC) management is shifting. We describe current clinical practice and outcomes of mBC patients as a benchmark for translation of developments into clinical practice in the near future. Patients and methods: Nation-wide population-based cohort study including all patients diagnosed with synchronous metastatic bladder cancer in the Netherlands in 2016-2017, identified through the Netherlands...
Abstract
ATS scholar,
Volume 2, Issue 2, 7 1 2020, Pages 168-171
Gender Representation in Medical Emergency Training Videos. Perpetuating Bias.
Ju M, Andler C, Robinson M, van Schaik SM
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
European heart journal. Case reports,
Volume 4, Issue 6, 7 1 2020, Pages 1-5
To treat or not to treat: left ventricular thrombus in a patient with cerebral amyloid angiopathy: a case report.
Hilt AD, Rasing I, Schalij MJ, Wermer MJH
Background: Cerebral amyloid angiopathy (CAA) is an important cause of cognitive impairment and spontaneous lobar intracerebral haemorrhage in older individuals. When necessary, anticoagulant treatment in these patients comes with two dilemmas; significant intracerebral bleeding risk with treatment vs. high risk of embolic stroke with no treatment. Case summary: A 66-year-old female patient presented to the emergency clinic with a ST-elevation myocardial infarction. Her past medical history reve...
Abstract
American journal of physiology. Heart and circulatory physiology,
Volume 320, Issue 1, 4 1 2020, Pages H245-H247
A shock-free approach for ambulatory cardioversion in atrial fibrillation.
De Coster T
Atrial fibrillation (AF), the most common persistent arrhythmia, is terminated most effectively by electrical cardioversion. This therapy requires in-hospital sedation to relieve the pain caused by electric shocks. Recently, our research group showed how the heart itself could be enabled to detect and terminate arrhythmias, including AF, thereby revealing the discovery of fully biological, shock-free cardioversion. Because of its biological nature, neither electric shocks nor hardware/software i...
Abstract
Cited 6 times since 2020 (1.3 per year)
source: EuropePMC
CVIR endovascular,
Volume 3, Issue 1, 4 1 2020, Pages 91
Embolization of the false lumen using IMPEDE-FX embolization plugs as part of treatment of an infrarenal post-dissection aneurysm: a case report.
Jansen AS, van Schaik PM, Martens JM, Reijnen MMPJ
Background: This case report demonstrates the value of IMPEDE-FX plugs in an embolization procedure of a false lumen of an infrarenal post-dissection aneurysm. Case presentation: A 69-year-old patient was treated with mitral valve replacement, complicated by a Stanford type-A dissection. After 9 years he presented with an enlarging infrarenal post-dissection aneurysm. The false lumen was embolized using multiple IMPEDE-FX plugs as part of the treatment in addition to embolization of the inferior...
Abstract
Cited 13 times since 2020 (2.9 per year)
source: EuropePMC
Cancer treatment and research communications,
Volume 25, 4 1 2020, Pages 100264
Survival after radical cystectomy: Progressive versus De novo muscle invasive bladder cancer.
Vlaming M, Kiemeney LALM, van der Heijden AG
Background: Despite treatment with radical cystectomy, patients with muscle invasive bladder cancer (MIBC) have a poor survival. It has been reported that survival is worse in NMIBC patients who progressed to MIBC in comparison to patients with de novo MIBC. The objective of this study was to compare survival of progressive versus de novo MIBC. Secondary objective was to explain this difference in survival by clinicopathological factors. Methods: 431 patients with MIBC who underwent radical cyst...
Abstract
Cited 7 times since 2020 (1.6 per year)
source: EuropePMC
Veterinary journal (London, England : 1997),
Volume 268, 3 1 2020, Pages 105576
Emergence of fatal Mannheimia haemolytica infections in cattle in the Netherlands.
Biesheuvel MM, van Schaik G, Meertens NM, Peperkamp NH, van Engelen E, van Garderen E
In the Dutch national surveillance system, outbreaks of fatal infections by Mannheimia haemolytica (M. haemolytica) in dairy cows and veal calves have become apparent in recent years. These observations prompted an in-depth analysis of available pathology data over the period 2004-2018 to investigate changes in the occurrence and/or expression of M. haemolytica-associated cattle disease. With multilevel logistic regression models, time trends were identified and corrected for farm, season, patho...
Abstract
Cited 5 times since 2020 (1.1 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 21, Issue 23, 3 1 2020, Pages E9244
Assessment of Microvessel Permeability in Murine Atherosclerotic Vein Grafts Using Two-Photon Intravital Microscopy.
Baganha F, Ritsma L, Quax PHA, de Vries MR
Plaque angiogenesis and plaque hemorrhage are major players in the destabilization and rupture of atherosclerotic lesions. As these are dynamic processes, imaging of plaque angiogenesis, especially the integrity or leakiness of angiogenic vessels, can be an extremely useful tool in the studies on atherosclerosis pathophysiology. Visualizing plaque microvessels in 3D would enable us to study the architecture and permeability of adventitial and intimal plaque microvessels in advanced atherosclerot...
Abstract
Cited 16 times since 2020 (3.5 per year)
source: EuropePMC
European journal of pediatrics,
Volume 180, Issue 2, 2 1 2020, Pages 617-625
Predictive factors for surgical treatment in preterm neonates with necrotizing enterocolitis: a multicenter case-control study.
El Manouni El Hassani S, Niemarkt HJ, Derikx JPM, Berkhout DJC, Ballón AE, de Graaf M, de Boode WP, Cossey V, Hulzebos CV, van Kaam AH, Kramer BW, van Lingen RA, Vijlbrief DC, van Weissenbruch MM, Benninga MA, de Boer NKH, de Meij TGJ
Necrotizing enterocolitis (NEC) is one of the most common and lethal gastrointestinal diseases in preterm infants. Early recognition of infants in need for surgical intervention might enable early intervention. In this multicenter case-control study, performed in nine neonatal intensive care units, preterm born infants (< 30 weeks of gestation) diagnosed with NEC (stage ≥ IIA) between October 2014 and August 2017 were divided into two groups: (1) medical (conservative treatment) and (2) surgi...
Abstract
