Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6128 results
Journal of cardiovascular electrophysiology, Volume 19, Issue 2, 20 3 2007, Pages 133-135 The role of positron emission tomography in evaluation of alterations in cardiac efficiency after cardiac resynchronization therapy. Ypenburg C, Bax JJ
Cited 230 times since 2007 (13.3 per year) source: EuropePMC
Circulation research, Volume 102, Issue 2, 15 3 2007, Pages 257-264 Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction. Timmers L, Sluijter JP, van Keulen JK, Hoefer IE, Nederhoff MG, Goumans MJ, Doevendans PA, van Echteld CJ, Joles JA, Quax PH, Piek JJ, Pasterkamp G, de Kleijn DP
Left ventricular (LV) remodeling leads to congestive heart failure and is a main determinant of morbidity and mortality following myocardial infarction. Therapeutic options to prevent LV remodeling are limited, which necessitates the exploration of alternative therapeutic targets. Toll-like receptors (TLRs) serve as pattern recognition receptors within the innate immune system. Activation of TLR4 results in an inflammatory response and is involved in extracellular matrix degradation, both key pr... Abstract
Cited 10 times since 2007 (0.6 per year) source: EuropePMC
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Volume 23, Issue 2, 14 2 2007, Pages 601-607 Prognostic significance of renal function in patients undergoing dobutamine stress echocardiography. Karagiannis SE, Feringa HH, Elhendy A, van Domburg R, Chonchol M, Vidakovic R, Bax JJ, Karatasakis G, Athanasopoulos G, Cokkinos DV, Poldermans D
Background: Dobutamine stress echocardiography (DSE) is used for risk stratification of patients with suspected coronary artery disease (CAD). However, the prognostic value of DSE among the entire strata of renal function has yet to be determined. We assessed the prognostic value of renal function relative to DSE findings. Methods: We studied 2292 patients, divided into 729 (32%) patients with normal renal function [creatinine clearance (CrCl) >90 ml/min] and 1563 (68%) with renal dysfunction... Abstract
Cited 87 times since 2007 (5 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 50, Issue 21, 7 1 2007, Pages 2071-2077 Acute effects of initiation and withdrawal of cardiac resynchronization therapy on papillary muscle dyssynchrony and mitral regurgitation. Ypenburg C, Lancellotti P, Tops LF, Bleeker GB, Holman ER, Piérard LA, Schalij MJ, Bax JJ
Objectives: The purpose of this study was to evaluate the relationship between dyssynchrony involving the mitral valve apparatus and the acute improvement in mitral regurgitation (MR) after cardiac resynchronization therapy (CRT). The effect of interruption of CRT at 6 months' follow-up on dyssynchrony and MR was also evaluated. Background: Mitral regurgitation may improve acutely after CRT, but the precise mechanism is not fully understood. Methods: Out of 63 consecutive patients with base... Abstract
Cited 19 times since 2007 (1.1 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 94, Issue 3, 5 1 2007, Pages e9 Triplane tissue Doppler imaging: a novel three-dimensional imaging modality that predicts reverse left ventricular remodelling after cardiac resynchronisation therapy. Van de Veire NR, Yu CM, Ajmone-Marsan N, Bleeker GB, Ypenburg C, De Sutter J, Zhang Q, Fung JW, Chan JY, Holman ER, van der Wall EE, Schalij MJ, Bax JJ
Background: Several two-dimensional (2-D) tissue Doppler imaging (TDI) echocardiographic techniques have proved useful to identify responders to cardiac resynchronisation therapy (CRT). Recently a 3-D probe allowing simultaneous acquisition of TDI data in three imaging planes became available. Objective: To evaluate the value of triplane TDI to predict reverse left ventricular (LV) remodelling after CRT. Methods: Sixty patients with heart failure, scheduled for CRT, underwent triplane echocardio... Abstract
Cited 10 times since 2007 (0.6 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 21, Issue 5, 1 1 2007, Pages 512.e5-7 Iatrogenic perforation of the posterior mitral valve leaflet: a rare complication of pacemaker lead placement. Konings TC, Koolbergen DR, Bouma BJ, Groenink M, Mulder BJ
An inadvertently placed pacing lead in the left ventricle (LV) is a rare and often underdiagnosed complication of pacemaker implantation. We present a case of a 73-year-old woman who was evaluated for dyspnea, 10 years after transvenous pacemaker implantation. Transthoracic and transesophageal echocardiography revealed a secundum atrial septal defect through which the ventricular pacing lead was placed into the LV. Whereas percutaneous extraction of the lead seemed too full of risk, the patient... Abstract
Cited 1 times since 2007 (0.1 per year) source: EuropePMC
Clinical nuclear medicine, Volume 32, Issue 11, 1 1 2007, Pages 835-838 Reliability of bone scintigraphy for suspected scaphoid fractures. Beeres FJ, Hogervorst M, Rhemrev SJ, Le Cessie S, Arndt JW, Stokkel MP, Bartlema KA, Hamming JF
Purpose: To examine the observer variation for bone scintigraphy in the detection of occult scaphoid fractures in daily practice, using only the early bone scanning images. Methods: One hundred bone scans of patients with a suspected scaphoid fracture but negative initial radiographs were prospectively included to calculate the inter- and intraobserver variation. Three nuclear medicine physicians independently evaluated all bone scans at 2 different points in time with a 3-month interval. The ob... Abstract
Cited 7 times since 2007 (0.4 per year) source: EuropePMC
Annals of vascular surgery, Volume 21, Issue 6, 1 1 2007, Pages 780-789 Glycemic control, lipid-lowering treatment, and prognosis in diabetic patients with peripheral atherosclerotic disease. Feringa HH, Karagiannis SE, Vidakovic R, Elhendy A, Schouten O, Boersma E, Bax JJ, Poldermans D
Glycemic control may be an underestimated risk factor in diabetic patients with peripheral arterial disease (PAD). Chronic statin therapy may improve glycemic control and outcome in these patients. In an observational cohort study of 425 consecutive diabetic patients with PAD, chronic statin therapy was noted, the ankle-brachial index was measured, and serial glycemic hemoglobin (HbA(1c)) measurements were obtained. During follow-up (median 7 years), all-cause mortality and cardiac death occurre... Abstract
Cited 14 times since 2007 (0.8 per year) source: EuropePMC
American heart journal, Volume 154, Issue 5, 1 1 2007, Pages 954-961 Statin therapy is associated with improved outcomes in vascular surgery patients with renal impairment. Welten GM, Chonchol M, Hoeks SE, Schouten O, Dunkelgrün M, van Gestel YR, Goei D, Bax JJ, van Domburg RT, Poldermans D
Background: Little is known about the association between baseline kidney function, statin therapy, and outcome after vascular surgery in patients with and without chronic kidney disease. Methods: A total of 2126 patients underwent elective major vascular surgery and were divided into 2 categories based on baseline creatinine clearance (CrCl), calculated using the Cockcroft-Gault equation: CrCl > or = 60 mL/min (n = 1358, reference) and CrCl < 60 mL/min (n = 768). Outcome measures were 30-... Abstract
Cited 19 times since 2007 (1.1 per year) source: EuropePMC
Coronary artery disease, Volume 18, Issue 7, 1 1 2007, Pages 571-576 The prevalence and prognosis of unrecognized myocardial infarction and silent myocardial ischemia in patients undergoing major vascular surgery. Feringa HH, Karagiannis SE, Vidakovic R, Elhendy A, ten Cate FJ, Noordzij PG, van Domburg RT, Bax JJ, Poldermans D
Objective: The aim of this study is to determine the prevalence and prognosis of unrecognized myocardial infarction (MI) and silent myocardial ischemia in vascular surgery patients. Methods: In a cohort of 1092 patients undergoing preoperative dobutamine stress echocardiography and noncardiac vascular surgery, unrecognized MI was determined by rest wall motion abnormalities in the absence of a history of MI. Silent myocardial ischemia was determined by stress-induced wall motion abnormalities in... Abstract
Cited 359 times since 2007 (20.7 per year) source: EuropePMC
Stem cell research, Volume 1, Issue 2, 1 1 2007, Pages 129-137 Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium. Timmers L, Lim SK, Arslan F, Armstrong JS, Hoefer IE, Doevendans PA, Piek JJ, El Oakley RM, Choo A, Lee CN, Pasterkamp G, de Kleijn DP
Although paracrine effects of mesenchymal stem cells (MSCs) have been suggested previously, cardioprotection by human MSC secretions has never been demonstrated. Human MSC-conditioned medium (CM) was collected by following a clinically compliant protocol. In a porcine model of ischemia and reperfusion injury, intravenous and intracoronary MSC-CM treatment significantly reduced myocardial nuclear oxidative stress as determined by immunostaining for 8-hydroxy-2'-deoxyguanosine. In addition, e... Abstract
Cited 83 times since 2007 (4.8 per year) source: EuropePMC
Journal of the American Geriatrics Society, Volume 55, Issue 11, 1 1 2007, Pages 1777-1785 Association between apolipoprotein E4 and cognitive decline in elderly adults. Packard CJ, Westendorp RG, Stott DJ, Caslake MJ, Murray HM, Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Cobbe SM, Ford I, Gaw A, Hyland M, Jukema JW, Kamper AM, Macfarlane PW, Jolles J, Perry IJ, Sweeney BJ, Twomey C, Prospective Study of Pravastatin in the Elderly at Risk Group
Objective: To determine the influence of apolipoprotein E on cognitive decline in a cohort of elderly men and women. Design: Prospective study. Setting: Scotland, Ireland, and the Netherlands. Participants: Five thousand eight hundred four subjects aged 70 to 82 from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Measurements: Subjects were assessed at baseline and over a mean 3.2-year (range 0.7-4.2) follow-up for memory (Picture-Word Recall), speed of information proces... Abstract
Cited 23 times since 2007 (1.3 per year) source: EuropePMC
International journal of cardiology, Volume 131, Issue 2, 1 1 2007, Pages 285-287 Effect of EPO administration on myocardial infarct size in patients with non-STE acute coronary syndromes; results from a pilot study. Liem A, van de Woestijne AP, Bruijns E, Roeters van Lennep HW, de Boo JA, van Halteren HK, van Es TP, Jukema JW, van der Laarse A, Zwinderman AH, van Veldhuisen DJ
A pilot study was performed to determine the effect of 40,000 IU Epo on myocardial damage in 51 patients with non-ST segment elevation acute coronary syndrome (non-STE ACS). No significant difference in myocardial damage was found, but an increased systolic blood pressure was noticed. Abstract
Cited 1 times since 2007 (0.1 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 151, Issue 46, 1 1 2007, Pages 2580-2585 [Percutaneous implantation of a pulmonary valve in 3 children with surgically corrected cardiac anomalies]. Bökenkamp R, Hazekamp MG, Schalij MJ, Clur SA, Ottenkamp J, Blom NA
An 11-year-old girl, a 15-year-old boy and a 12-year-old girl all underwent percutaneous implantation of a Melody pulmonary valve prosthesis to replace a stenotic and insufficient homograft in the pulmonary artery. Preoperatively, 2 of the children suffered from fatigue and dyspnoea on exertion The homografts had been implanted between the ages of 1-2, to establish surgical continuity between the right ventricle and the pulmonary artery. The anomalies were tetralogy of Fallot, pulmonary atresia... Abstract
Cited 53 times since 2007 (3.1 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 93, Issue 11, 1 1 2007, Pages 1461-1470 Multi-modality imaging to assess left atrial size, anatomy and function. Tops LF, van der Wall EE, Schalij MJ, Bax JJ
The left atrium (LA) anterior-posterior diameter was one of the first standardised echocardiographic parameters. However, the clinical importance of LA size assessment has been neglected for some time. Recent population-based studies have demonstrated the prognostic value of LA size for long-term outcome. Furthermore, with new dedicated techniques such as tissue Doppler imaging, it has become feasible to assess (regional) LA function. In addition, the introduction of catheter ablation procedures... Abstract
Cited 23 times since 2007 (1.3 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 93, Issue 11, 1 1 2007, Pages 1339-1350 Optimal use of echocardiography in cardiac resynchronisation therapy. Bleeker GB, Yu CM, Nihoyannopoulos P, de Sutter J, Van de Veire N, Holman ER, Schalij MJ, van der Wall EE, Bax JJ
Echocardiography has several roles in patients with cardiac resynchronisation therapy (CRT). First, it can optimise selection of CRT candidates by demonstration of left ventricular (LV) dyssynchrony. Second, it can be used to assess immediate response to CRT, including detection of acute LV resynchronisation. Echocardiography is also useful to evaluate long-term benefit from CRT. Finally, echocardiography is important in optimisation of pacemaker settings, including AV and VV optimisation. Abstract
Nederlands tijdschrift voor geneeskunde, Volume 151, Issue 47, 1 1 2007, Pages 2615-2619 [The endocannabinoid system, overweight, and the CB1-endocannabinoid-receptor antagonist rimonabant]. Boekholdt SM, Jukema JW, Peters RJ
--Obesity is an important healthcare issue. --Recent research has led to insights into the role of the endocannabinoid system in the regulation of body weight. --Rimonabant is a CB1-endocannabinoid-receptor antagonist. --Four trials were published recently on the efficacy and safety of rimonabant in the treatment of people with obesity. --When combined with a hypocaloric diet, rimonabant 20 mg/day was more effective than placebo in achieving and maintaining weight loss. In addition, treatment wi... Abstract
Cited 162 times since 2007 (9.3 per year) source: EuropePMC
Circulation, Volume 116, Issue 20, 29 5 2007, Pages 2241-2252 Catheter ablation of ventricular tachycardia after repair of congenital heart disease: electroanatomic identification of the critical right ventricular isthmus. Zeppenfeld K, Schalij MJ, Bartelings MM, Tedrow UB, Koplan BA, Soejima K, Stevenson WG
Background: Catheter ablation of ventricular tachycardia (VT) after repair of congenital heart disease can be difficult because of nonmappable VTs and complex anatomy. Insights into the relation between anatomic isthmuses identified by delineating unexcitable tissue using substrate mapping techniques and critical reentry circuit isthmuses might facilitate ablation. Methods and results: Sinus rhythm voltage mapping of the right ventricle was performed in 11 patients with sustained VT after repair... Abstract
Cited 25 times since 2007 (1.4 per year) source: EuropePMC
Pathology, research and practice, Volume 203, Issue 12, 29 5 2007, Pages 863-872 Activation of signaling molecules and matrix metalloproteinases in right ventricular myocardium of rats with pulmonary hypertension. Umar S, Hessel M, Steendijk P, Bax W, Schutte C, Schalij M, van der Wall E, Atsma D, van der Laarse A
Pulmonary hypertension induces right ventricular (RV) overload, which is transmitted to cardiomyocytes via integrins that activate intracellular messengers, including focal adhesion kinase (FAK) and neuronal nitric oxide synthase (NOS1). We investigated whether RV hypertrophy (RVH) and RV failure (RVF) were associated with activation of FAK, NOS1, and matrix metalloproteinases (MMPs). Rats were treated without (RVC) or with a low dose of monocrotaline (30mg/kg) to induce RVH, and with a high dos... Abstract
Cited 14 times since 2007 (0.8 per year) source: EuropePMC
The American journal of cardiology, Volume 100, Issue 12, 26 4 2007, Pages 1786-1791 Comparison with computed tomography of two ultrasound devices for diagnosis of abdominal aortic aneurysm. Vidakovic R, Feringa HH, Kuiper RJ, Karagiannis SE, Schouten O, Dunkelgrun M, Hoeks SE, Bom N, Bax JJ, Neskovic AN, Poldermans D
Screening for abdominal aortic aneurysms (AAAs) in patients at risk will become more cost effective if a simple, inexpensive, and reliable ultrasound device is available. The aim of this study was to compare a 2-dimensional, handheld ultrasound device and a newly developed ultrasound volume scanner (based on bladder scan technology) with computed tomography (CT) for diagnosing AAA. A total of 146 patients (mean age 69 +/- 10 years; 127 men) were screened for the presence of AAAs (diameter >3... Abstract